SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 31/JUL/2005
Date Updated: 12/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name DIMETHYL-D6 SULFATE, 99+ ATOM % D
Product Number 164526
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
DIMETHYL SULFATE-D6 MIN 99 ATOM % 15199-43-6 239-257-0 016-023-00-4
D
Formula C2D6O4S
Molecular Weight 126.12 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer. Also toxic if swallowed. Also very toxic by
inhalation. Causes burns. May cause sensitization by skin contact.
Also possible risks of irreversible effects.
Carc. Cat.2 Muta. Cat.3
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician. Do not induce vomiting.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Combustible liquid.
Explosion Hazards: Container explosion may occur under fire
conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area and keep personnel upwind.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed
container, and hold for waste disposal. Ventilate area and wash
spill site after material pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame. Store in a cool dry place.
SPECIAL REQUIREMENTS: Moisture sensitive.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 0.5 MG/M3
Poland NDSCh 1 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
ALDRICH - 164526 www.sigma-aldrich.com Page 2
OEL TWA 0.05 mg/m3
0.01 ppm
Remarks: HK
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 0.1 mg/m3
0.02 ppm
Remarks: 4
Remarks: H,TRK,TRGS 901-4
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 0.1 mg/m3
0.02 ppm
Remarks: H K
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 0.26 mg/m3
0.05 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
Special Protective Measures: Faceshield (8-inch minimum).
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 188 掳C 760 mmHg
MP/MP Range -32 掳C
Flash Point 83 掳C Method: closed cup
Flammability N/A
Autoignition Temp 495 掳C 495 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1.386 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solvent: 0.26 g/ml EtOH clear, colorless
10 - Stability and Reactivity
ALDRICH - 164526 www.sigma-aldrich.com Page 3
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Strong oxidizing agents, Strong bases,
Ammonia, Material generates methanol on contact with water or
moisture.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Methanol, Sulfuric acid.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
SENSITIZATION
Skin: May cause allergic skin reaction.
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Fever, headache, and malaise. Symptoms may be delayed. To the
best of our knowledge, the chemical, physical, and toxicological
properties have not been thoroughly investigated. Symptoms of
exposure may include burning sensation, coughing, wheezing,
laryngitis, shortness of breath, headache, nausea, and vomiting.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be harmful if absorbed through the skin.
Readily absorbed through skin.
Eye Contact: Causes burns. Lachrymator.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be fatal
if inhaled.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Heart. Lungs. Liver. Kidneys. Eyes. Brain.
CHRONIC EXPOSURE - CARCINOGEN
Result: This is or contains a component that has been reported
to be carcinogenic based on its IARC, OSHA, ACGIH, NTP, or EPA
classification.
SWEDISH OE CARCINOGEN: Substances which according to 23搂, AFS
2000:3, is allowed to use only after authorization from The
Swedish Work Environment Authority.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
ALDRICH - 164526 www.sigma-aldrich.com Page 4
14 - Transport Information
RID/ADR
UN#: 1595
Class: 6.1
PG: I
Proper Shipping Name: Dimethyl sulphate
IMDG
UN#: 1595
Class: 6.1
PG: I
Subrisk: 8
Proper Shipping Name: Dimethyl sulphate
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1595
Class: 6.1
PG: I
Subrisk: 8
Proper Shipping Name: Dimethyl sulphate
Inhalation Packing Group I: Yes
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 016-023-00-4
NOTA: E
INDICATION OF DANGER: T+
Very toxic.
R-PHRASES: 45 25 26 34 43 68
May cause cancer. Also toxic if swallowed. Also very toxic by
inhalation. Causes burns. May cause sensitization by skin
contact. Also possible risks of irreversible effects.
S-PHRASES: 53 45
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 1*
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
ALDRICH - 164526 www.sigma-aldrich.com Page 5
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
ALDRICH - 164526 www.sigma-aldrich.com Page 6
|