SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 31/JUL/2005
Date Updated: 14/MAR/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name DIMETHYLAMINE, ANHYDROUS, 99+%
Product Number 295280
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
DIMETHYLAMINE 124-40-3 204-697-4 612-001-00-9
Formula C2H7N
Molecular Weight 45.09 AMU
Synonyms Dimethylamine (ACGIH:OSHA) * Methanamine,
N-methyl- (9CI) * N-Methylmethanamine * RCRA
waste number U092
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Extremely flammable. Harmful by inhalation. Irritating to
respiratory system and skin. Risk of serious damage to eyes.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
Contamination of the eyes should be treated by immediate and
prolonged irrigation with copious amounts of water. Assure
adequate flushing of the eyes by separating the eyelids with
fingers.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Use water spray or fog nozzle to keep cylinder cool.
Move cylinder away from fire if there is no risk.
SPECIAL RISKS
Specific Hazard(s): Extremely flammable. Vapor may travel
considerable distance to source of ignition and flash back.
Emits toxic fumes under fire conditions.
Explosion Hazards: May form explosive mixtures with air Vapor
may travel considerable distance to source of ignition and flash
back. Container explosion may occur under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
SPECIFIC METHOD(S) OF FIRE FIGHTING
Do not extinguish burning gas if flow cannot be shut off
immediately. Use water spray or fog nozzle to keep cylinder
cool. Move cylinder away from fire if there is no risk.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area and keep personnel upwind. Shut off all sources of
ignition. Shut off leak if there is no risk.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe gas. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame. Use with equipment rated for cylinder
pressure, and of compatible materials of construction. Close
valve when not in use and when empty. Make sure cylinder is
properly secured when in use or stored Cylinder temperature
should not exceed 125掳F (52掳C).
Unsuitable: Store away from heat and direct sunlight
SPECIAL REQUIREMENTS: Contents under pressure.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Warning: suck-back into cylinder may cause rupture. Use
back-flow-preventive device in piping.
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WORK PRACTICES
Store and use with adequate ventilation.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 9 MG/M3
Poland NDSCh 18 MG/M3
Poland NDSP -
EXPOSURE LIMITS - EUROPEAN UNION
Source Type Value
OEL OEL 3.8 mg/m3
2 ppm
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 3.7 mg/m3
2 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 4 mg/m3
2 ppm
Remarks: =1=
Remarks: 20
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 4 mg/m3
2 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level3.5 mg/m3
2 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 4 mg/m3
2 ppm
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 3.8 mg/m3
2 ppm
OEL STEL 11 mg/m3
6 ppm
Remarks: Indicative limit value
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator in
nonventilated areas and/or for exposure above the TLV or PEL.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Compressed gas
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Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 7 掳C 760 mmHg
MP/MP Range -93 掳C
Flash Point -6.7 掳C Method: closed cup
Flammability N/A
Autoignition Temp 401 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.8 %
Upper: 14.4 %
Vapor Pressure 1277 mmHg 20 掳C
SG/Density 0.824 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 1.55 g/l 15 掳C
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides.
11 - Toxicological Information
RTECS NUMBER: IP8750000
ACUTE TOXICITY
LD50
Oral
Rat
698 mg/kg
Remarks: Behavioral:Excitement. Behavioral:Muscle weakness.
Gastrointestinal:Ulceration or bleeding from stomach.
LC50
Inhalation
Rat
4,540 ppm
6H
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Olfaction:Other changes. Sense Organs and Special Senses
(Nose, Eye, Ear, and Taste):Eye:Other. Lungs, Thorax, or
Respiration:Dyspnea.
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LD50
Oral
Mouse
316 mg/kg
Remarks: Behavioral:Excitement. Behavioral:Muscle weakness.
Gastrointestinal:Ulceration or bleeding from stomach.
LC50
Inhalation
Mouse
4,725 ppm
2H
LD50
Intraperitoneal
Mouse
736 MG/KG
LD50
Oral
Rabbit
240 mg/kg
Remarks: Behavioral:Excitement. Behavioral:Muscle weakness.
Gastrointestinal:Ulceration or bleeding from stomach.
LD50
Oral
Guinea pig
240 mg/kg
Remarks: Behavioral:Excitement. Behavioral:Muscle weakness.
Gastrointestinal:Ulceration or bleeding from stomach.
LC50
Inhalation
Mammal
3,700 mg/m3
IRRITATION DATA
Eyes
Rabbit
50 mg
5M
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure of the eyes to high concentrations may result in
ulceration of the conjunctiva and cornea with possible
destruction of all ocular tissues. Inhalation may result in
spasm, inflammation and edema of the larynxand bronchi, chemical
pneumonitis, and pulmonary edema. Symptoms of exposure may
include burning sensation, coughing, wheezing, laryngitis,
shortness of breath, headache, nausea, and vomiting.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: Harmful if absorbed through skin. Readily
absorbed through skin.
Eye Contact: Causes burns. Lachrymator.
Inhalation: Harmful if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract. Can cause rapid suffocation.
Ingestion: Harmful if swallowed.
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TARGET ORGAN INFORMATION
Liver.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that is not
classifiable as to its carcinogenicity based on its IARC, ACGIH,
NTP, or EPA classification.
CHRONIC EXPOSURE - MUTAGEN
Rat
50 UG/M3
Inhalation
Cytogenetic analysis
Hamster
10 MMOL/L
Cell Type: ovary
Cytogenetic analysis
Hamster
500 UMOL/L
Cell Type: ovary
Sister chromatid exchange
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
CONTAMINATED CONTAINER DISPOSAL
Caution: no-return cylinder. Do not reuse. Empty cylinder will
contain hazardous residue. Follow proper disposal techniques.
14 - Transport Information
RID/ADR
UN#: 1032
Class: 2
Proper Shipping Name: Dimethylamine, anhydrous
IMDG
UN#: 1032
Class: 2.1
Proper Shipping Name: Dimethylamine, anhydrous
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1032
Class: 2.1
Proper Shipping Name: Dimethylamine, anhydrous
Inhalation Packing Group I: No
15 - Regulatory Information
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CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 612-001-00-9
NOTA: 5
INDICATION OF DANGER: F+ Xn
Extremely Flammable. Harmful.
R-PHRASES: 12 20 37/38 41
Extremely flammable. Harmful by inhalation. Irritating to
respiratory system and skin. Risk of serious damage to eyes.
S-PHRASES: 16 26 29
Keep away from sources of ignition - no smoking. In case of
contact with eyes, rinse immediately with plenty of water and
seek medical advice. Do not empty into drains.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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