Inco 庐
Jinco Nonferrous Metals Co. Ltd. China
INCOMOND Nickel Sulphate
Hazardous Ingredients
Inco PEL1鈥搈g/m3 TLV1,2 鈥搈g/m3
Hazardous Ingredients C.A.S. No
Nickel Chloride Hexahydrate
10101-97-0 0.1 as NI 0.1* as Ni
(NiSO4 鈥? 6H2O)
Material *as inhalable fraction
Physical and Chemical Data
Blue/white crystals.
Safety Specific m.p.掳C / Sol. In H20
Ingredient Mol. Wt. pH 40% sol鈥檔
Gravity b.p.掳C g/100ml
>60 鈥? cold
NiSO4 鈥? 6H2O 262.86 2.07 n.av. >3
Data >340 鈥? hot
Other: decomposes on heating.
Physical Hazards
Sheet
None.
Health Hazards
Nickel Sulphate, Hexahydrate
LD50 ORAL RAT: 300 mg/kg
The International Agency for Research on Cancer (IARC) [4] in 1990 and
Inhalation:
the U.S. Tenth Report on Carcinogens [5] in 2002 concluded there was
sufficient evidence that nickel compounds are carcinogenic to humans.
Toxicology Excellence for Risk Assessment (TERA) finds that
carcinogenic risk from soluble nickel compounds via inhalation cannot
be determined (Class D) because the existing evidence is composed of
conflicting data [6].
Epidemiological studies of Norwegian nickel refinery workers showed
than an increased risk of respiratory cancer was present in electrolysis
plant workers. These workers had mixed exposure to aerosols of nickel
sulphate and nickel chloride and to insoluble forms of nickel. Electrolysis
plant workers in an Ontario refinery similarly exposed to nickel sulphate
and nickel chloride aerosols, but not the dust from matte roasting
operations, did not show any increased incidence of respiratory cancer.
Exposure to aerosols of nickel sulphate can cause asthma and
irritation of the upper respiratory tract. Repeated intraperitoneal
injections (50 x 1 mg Ni) of nickel sulphate in rats produced abdominal
tumours.
Skin Contact: Exposure to aerosols and solutions of nickel sulphate can cause skin
irritation, nickel sensitivity and allergic skin rashes.
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Eye Contact: May cause irritation.
Wounds: Neither single nor repeated intramuscular injections of nickel sulphate
have resulted in the development of tumours in rodents.
Ingestion: The U.S. National Institute for Occupational Safety and Health
(NIOSH) concluded there is no evidence that nickel and its inorganic
compounds are carcinogenic when ingested.
Preexisting Conditions: Skin contact can cause an allergic skin rash and/or asthma in previously
Inco sensitized individuals.
Reproductive Toxicity: Animal experiments indicate that soluble nickel ingestion causes
adverse effects on fetal development at a threshold oral exposure of 2.2
Material mg/ Ni/kg/day by pregnant rats. Data are insufficient to determine if this
effect occurs in humans and no regulatory agency has classified soluble
forms of nickel as reproductive risks for humans.
Safety Precautions for Safe Storage, Handling and Use
Do not inhale dust or mist containing nickel sulphate. Keep container closed when not in use. Ventilation
is normally required when handling or using this product to keep exposure to airborne nickel below the
Data exposure limit. If ventilation alone cannot so control exposure, use NIOSH-approved respirators selected
according to local regulatory standards. Maintain airborne nickel levels as low as possible.
Avoid skin contact. Wear suitable eye protection and gloves. Wash skin thoroughly after handling, and
Sheet before eating, drinking or smoking. Launder clothing and gloves as needed.
Spill, Leak and Disposal Procedure
Collect spill of dry nickel sulphate crystals by sweeping with sweeping compound or by vacuuming with
the vacuum exhaust passing through a high efficiency particulate arresting (HEPA) filter if the exhaust is
discharged into the workplace. Leaked or spilled solutions should be treated with lime and the solids
recovered.
Wear appropriate NIOSH-approved respirators if collection and disposal of spills is likely to cause the
concentration of airborne nickel to exceed the PEL.
Nickel-containing waste is normally collected to recover nickel values. Should waste disposal be deemed
necessary, follow local regulations.
Emergency and First Aid Procedures
In case of contact with eyes, immediately flush eyeballs with plenty of water for 15 minutes. Seek medical
attention immediately.
In case of accidental ingestion of amounts less than about 1 gram, drink large quantities of water. For
larger amounts, seek medical attention immediately.
For skin rashes, seek medical attention.
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Notes and Bibliography
Inco believes that the information in this Material Safety Data Sheet is accurate. However, Inco makes
no express or implied warranty as to the accuracy of such information and expressly disclaims any
liability resulting from reliance on such information.
Manufactured by:
Jinco Nonferrous Metals Co., Ltd.,
No. 159 Qing Yang South Road
Kunshan Economic & Technical Development Zone
Inco Kunshan City 215300
Jiangshu, P.R. China.
Emergency Telephone No., 0086 {0}512 57712666 Ext., 806.
Under licence from, INCO Limited.
Material Footnotes:
庐 Trademark of the Inco family of companies.
Safety 1 OSHA Permissible Exposure Limit
2 Threshold Limit Value of the American Conference of Governmental Industrial Hygienists.
Data 3 Describes possible health hazards of the product supplied. If user operations change it to other
chemical forms, whether as end products, intermediates or fugitive emissions, the possible health
hazards of such forms must be determined by the user.
4 IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 49, World Health
Sheet Organization, 1990
U.S. National Toxicology Program (NTP), 鈥?10th Report on Carcinogens, December 2002
5
6 Toxicology Excellence for Risk Assessment (TERA), 鈥淭oxicological Review of Soluble Nickel
Salts鈥?. Report prepared for US EPA, Health Canada and the Metal Finishing Association of
Southern California, March 1999.
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