SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 12/MAY/2005
Date Updated: 12/MAR/2004
Version 1.5
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name PROPIONIC ACID, 99.5%
Product Number 537047
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
PROPIONIC ACID 79-09-4 201-176-3 607-089-00-0
Formula C3H6O2
Molecular Weight 74.08 AMU
Synonyms Acide propionique (French) * Carboxyethane *
Ethanecarboxylic acid * Ethylformic acid *
Kyselina propionova (Czech) * Luprosil *
Metacetonic acid * Methyl acetic acid *
Propanoic acid * Propionic acid (ACGIH) *
Propionic acid grain preserver * Prozoin *
Pseudoacetic acid * Sentry grain preserver *
Tenox P grain preservative
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Causes burns.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician. Do not induce vomiting.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Combustible liquid. Emits toxic fumes under
fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed
container, and hold for waste disposal. Ventilate area and wash
spill site after material pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame. Store in a cool dry place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 30 mg/m3
Poland NDSCh 45 mg/m3
Poland NDSP
EXPOSURE LIMITS - EUROPEAN UNION
Source Type Value
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OEL OEL 31 mg/m3
10 ppm
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 30 mg/m3
10 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 31 mg/m3
Remarks: =1=
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 30 mg/m3
10 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level30 mg/m3
10 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 30 mg/m3
10 ppm
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 31 mg/m3
10 ppm
OEL STEL 46 mg/m3
15 ppm
Remarks: Indicative limit value
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
Special Protective Measures: Faceshield (8-inch minimum).
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH 2.5 20 掳C Concentration: 100
g/l
BP/BP Range 141 - 142 掳C
MP/MP Range -24 - -23 掳C
Flash Point 54 掳C Method: closed cup
Flammability N/A
Autoignition Temp 513 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.9 %
Upper: 12.1 %
Vapor Pressure 2.4 mmHg 20 掳C
SG/Density 0.992 g/cm3
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Partition Coefficient Log Kow: 0.25
Viscosity 10 Pas 25 掳C
Vapor Density 2.55 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension 27.21 mN/m 15 掳C
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: ALCOHOL, ETHER, CHLOROFORM
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: UE5950000
ACUTE TOXICITY
LD50
Oral
Rat
*
LD50
Skin
Rabbit
500 mg/kg
LC50
Inhalation
Rat
>4.9 MG/L
4 HR
LD50
Oral
Rat
2600 mg/kg
LD50
Parenteral
Rat
3500 MG/KG
LD50
Intravenous
Mouse
625 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
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LD50
Skin
Rabbit
500 UL/KG
LD50
Oral
Mammal
1640 mg/kg
IRRITATION DATA
Skin
Rabbit
Remarks: Severe irritation effect
Skin
Rabbit
495 mg
Remarks: Open irritation test
Eyes
Rabbit
0.99 mg
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. May cause an asthmatic-like bronchitis. Nausea,
dizziness, and headache. Blood effects.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: Harmful if absorbed through skin. Readily
absorbed through skin.
Eye Contact: Causes burns.
Inhalation: May be harmful if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Central nervous system. Blood. Liver. Kidneys.
CHRONIC EXPOSURE - MUTAGEN
Human
2500 UMOL/L
Cell Type: lymphocyte
Sister chromatid exchange
12 - Ecological Information
ELIMINATION
Elimination: > 70 %
ECOTOXICOLOGICAL EFFECTS
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Test Type: EC50 Algae
Time: 72 h
Value: 45.8 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 21 - 24.6 mg/l
Test Type: LC50 Fish
Species: Lepomis macrochirus (Bluegill)
Time: 96 h
Value: 73 - 115 mg/l
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: 51 - 73.2 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations. This combustible material may be burned
in a chemical incinerator equipped with an afterburner and
scrubber.
14 - Transport Information
RID/ADR
UN#: 1848
Class: 8
PG: III
Proper Shipping Name: Propionic acid
IMDG
UN#: 1848
Class: 8
PG: III
Subrisk: 3
Proper Shipping Name: Propionic acid
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1848
Class: 8
PG: III
Proper Shipping Name: Propionic acid
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 607-089-00-0
NOTA: B
INDICATION OF DANGER: C
Corrosive.
R-PHRASES: 34
Causes burns.
S-PHRASES: 36/37/39 26 45
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Wear suitable protective clothing, gloves, and eye/face
protection. In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice. In case of
accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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