SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 12/MAY/2005
Date Updated: 25/JUN/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 1-PROPANOL, 99+%
Product Number W292818
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
1-PROPANOL, FOR MANUFACTURING 71-23-8 200-746-9 603-003-00-0
Formula C3H8O
Molecular Weight 60.1 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Risk of serious damage to eyes. Vapors may cause
drowsiness and dizziness.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid breathing vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep container closed. Keep away from
heat, sparks, and open flame.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Mechanical
exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 500 mg/m3
200 ppm
Remarks: H
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 245 mg/m3
100 ppm
Remarks: H
ALDRICH - W292818 www.sigma-aldrich.com Page 2
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 500 mg/m3
200 ppm
Remarks: H
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 500 mg/m3
200 ppm
OEL STEL 625 mg/m3
250 ppm
Remarks: Skin
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 97 掳C 760 mmHg
MP/MP Range -127 掳C
Flash Point 15 掳C Method: closed cup
Flammability N/A
Autoignition Temp 371 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.1 %
Upper: 13.7 %
Vapor Pressure 14.9 mmHg 20 掳C
SG/Density 0.8 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 2.1 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
ALDRICH - W292818 www.sigma-aldrich.com Page 3
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: UH8225000
IRRITATION DATA
Skin
Rabbit
500 mg
Remarks: Open irritation test
Eyes
Rabbit
20 mg
24H
Remarks: Moderate irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Can cause CNS depression. Prolonged exposure can cause: Narcotic
effect. Drying, cracking, or irritation of the skin.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes severe eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Nerves. Liver.
CHRONIC EXPOSURE - CARCINOGEN
Rat
Route of Application: Oral
Exposure Time: 81W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Liver:Tumors. Blood:Leukemia
Rat
Route of Application: Subcutaneous
Exposure Time: 95W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Liver:Tumors. Blood:Leukemia
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 7000 PPM/7H
Route of Application: Inhalation
Exposure Time: (1-19D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 7000 PPM/7H
Route of Application: Inhalation
ALDRICH - W292818 www.sigma-aldrich.com Page 4
Exposure Time: (6W MALE)
Result: Effects on Fertility: Male fertility index (e.g., #
males impregnating females per # males exposed to fertile
nonpregnant females).
Species: Rat
Dose: 10000 PPM/7H
Route of Application: Inhalation
Exposure Time: (1-19D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death. Specific Developmental
Abnormalities: Musculoskeletal system.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1274
Class: 3
PG: II
Proper Shipping Name: n-Propanol
IMDG
UN#: 1274
Class: 3
PG: II
Proper Shipping Name: n-Propanol
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1274
Class: 3
PG: II
Proper Shipping Name: n-Propanol
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 603-003-00-0
NOTA: C
INDICATION OF DANGER: F Xi
Highly Flammable. Irritant.
R-PHRASES: 11 41 67
Highly flammable. Risk of serious damage to eyes. Vapors may
cause drowsiness and dizziness.
S-PHRASES: 7 16 24 26 39
Keep container tightly closed. Keep away from sources of
ALDRICH - W292818 www.sigma-aldrich.com Page 5
ignition - no smoking. Avoid contact with skin. In case of
contact with eyes, rinse immediately with plenty of water and
seek medical advice. Wear eye/face protection.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
NORWAY
Labelling for organic solvents where the package is 1liter or
more.
YL-tall m3/l: 3265
YL-group: 5
Risk phrases: 20
Harmful by inhalation.
Safety phrases: 38 42 210
In case of insufficient ventilation, wear suitable respiratory
equipment. During fumigation/spraying wear suitable respiratory
equipment. Use compressed air- or fresh air line breathing
apparatus in confined spaces.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
ALDRICH - W292818 www.sigma-aldrich.com Page 6
|