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MSDS Material Safety Data Sheet
CAS

333-20-0

File Name: 333-20-0.asp

                              SIGMA-ALDRICH

Material Safety Data Sheet

Date Printed: 12/MAY/2005
Date Updated: 16/NOV/2004
Version 1.12
According to 91/155/EEC

Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.

1 - Product and Company Information

Product Name POTASSIUM THIOCYANATE SIGMAULTRA
Product Number P2713

Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566

2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
POTASSIUM THIOCYANATE 333-20-0 206-370-1 615-004-00-3

Formula KSCN
Molecular Weight 97.18 AMU
Synonyms Arterocyn * Aterocyn * Kyonate * Potassium
isothiocyanate * Potassium rhodanate * Potassium
sulfocyanate * Potassium thiocyanide * Rhocya *
Rodanca * Thio-cara

3 - Hazards Identification

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful by inhalation, in contact with skin and if swallowed.
Contact with acids liberates very toxic gas. Harmful to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.


4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

5 - Fire Fighting Measures

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.

SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.

STORAGE
Conditions of Storage: Keep tightly closed.

SPECIAL REQUIREMENTS: Light and moisture sensitive.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.

GENERAL HYGIENE MEASURES
Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

9 - Physical and Chemical Properties

Appearance Physical State: Solid

Property Value At Temperature or Pressure


SIGMA - P2713 www.sigma-aldrich.com Page 2
pH 5.3 - 8.7
BP/BP Range N/A
MP/MP Range 173 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1.89 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:1 M in H2O, 20掳C
complete, colorless

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Conditions of Instability: May decompose on exposure to light.
Conditions to Avoid: Moisture.
Materials to Avoid: Acids, Strong bases.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides, Potassium, Hydrogen cyanide.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

RTECS NUMBER: XL1925000

ACUTE TOXICITY

LDLO
Oral
Human
80 mg/kg
Remarks: Behavioral:Hallucinations, distorted perceptions.
Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Muscle weakness.

LD50
Oral
Rat
854 mg/kg
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea.


SIGMA - P2713 www.sigma-aldrich.com Page 3
LD50
Oral
Mouse
594 mg/kg
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea.

LD50
Intraperitoneal
Mouse
600 MG/KG

LD50
Intravenous
Mouse
88200 UG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea.

SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Nausea, headache, and vomiting. To the best
of our knowledge, the chemical, physical, and toxicological
properties have not been thoroughly investigated.

ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: Harmful if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.

TARGET ORGAN INFORMATION
Central nervous system. Cardiovascular system. Thyroid.

CHRONIC EXPOSURE - MUTAGEN

ZINCL
Histidine reversion (Ames)

CHRONIC EXPOSURE - TERATOGEN

Species: Domestic Animals
Dose: 1779 MG/KG
Route of Application: Oral
Exposure Time: (1-20W PREG)
Result: Specific Developmental Abnormalities: Endocrine system.

12 - Ecological Information

ECOTOXICOLOGICAL EFFECTS

Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 11 mg/l

Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: > 100 mg/l


SIGMA - P2713 www.sigma-aldrich.com Page 4
13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

14 - Transport Information

RID/ADR
Non-hazardous for road transport.

IMDG
Non-hazardous for sea transport.

IATA
Non-hazardous for air transport.

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 615-004-00-3
NOTA: A
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 20/21/22 32 52/53
Harmful by inhalation, in contact with skin and if swallowed.
Contact with acids liberates very toxic gas. Harmful to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
S-PHRASES: 13 61
Keep away from food, drink, and animal feedingstuffs. Avoid
release to the environment. Refer to special
instructions/safety data sheets.

COUNTRY SPECIFIC INFORMATION

Germany
WGK: 1

SWITZERLAND
SWISS POISON CLASS: 3

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIMER


SIGMA - P2713 www.sigma-aldrich.com Page 5
For R&D use only. Not for drug, household or other uses.




SIGMA - P2713 www.sigma-aldrich.com Page 6

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