SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 20/OCT/2004
Date Updated: 12/MAR/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name ACRYLAMIDE:N,N'-METHYLENEBISACRYLAM.19:1
SOL., 40% IN H2O
Product Number 01693
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
ACRYLAMIDE BIS-ACRYLAMIDE None None None
SOLUTION (28% - 40% ACRYLAMIDE)
Ingredient Name Percent CAS # EC no Annex I
Index Number
WATER 60 7732-18-5 231-791-2 None
ACRYLAMIDE >= 28.5 79-06-1 201-173-7 616-003-00-0
<= 40
Carc. Cat.2 Muta. Cat.2
Symbols: T
R-Phrases: 45 46 20/21 25 36/38 43 48/23/24/25 62
May cause cancer. May cause heritable genetic damage. Also harmful
by inhalation and in contact with skin. Also toxic if swallowed.
Irritating to eyes and skin. May cause sensitization by skin
contact. Also toxic: danger of serious damage to health by
prolonged exposure through inhalation, in contact with skin and if
swallowed. Possible risk of impaired fertility.
N,N'-METHYLENE >= 1 110-26-9 203-750-9 None
BIS(ACRYLAMIDE) <= 1.5
Symbols: Xn
R-Phrases: 20/22
Harmful by inhalation and if swallowed.
Formula C3H5NO
Molecular Weight 71.08 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer. May cause heritable genetic damage. Also harmful
by inhalation and in contact with skin. Also toxic if swallowed.
Irritating to eyes and skin. May cause sensitization by skin
contact. Also toxic: danger of serious damage to health by
prolonged exposure through inhalation, in contact with skin and if
swallowed. Possible risk of impaired fertility.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Explosion Hazards: Container explosion may occur under fire
conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
prolonged or repeated exposure. Do not get in eyes, on skin, on
clothing.
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STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Unstable.
Conditions to Avoid: Air sensitive.
Materials to Avoid: Avoid contact with acid., Bases, Oxidizing
agents, Reducing agents Iron and iron salts., Copper, Aluminum,
Brass, Free radical initiators
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Ammonia.
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HAZARDOUS POLYMERIZATION
Hazardous Polymerization: May occur
Hazardous Polymerization Reactions: May polymerize on exposure to
light.
11 - Toxicological Information
SENSITIZATION
Respiratory: May cause allergic respiratory reaction.
Skin: May cause allergic skin reaction.
SIGNS AND SYMPTOMS OF EXPOSURE
Acrylamide toxicity is manifested as a sensorimotor peripheral
neuropathy. Symptoms include: drowsiness, loss of balance,
confusion, memory loss, hallucinations, numbness, paresthesias
(ataxia, tremor, dysarthria), and incoordination.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: Toxic if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: Toxic if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Nerves. Kidneys.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be probably carcinogenic based on its IARC, OSHA,
ACGIH, NTP, or EPA classification.
CHRONIC EXPOSURE - TERATOGEN
Result: Possible risk of congenital malformation in the fetus.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: May cause reproductive disorders.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
IMDG
UN#: 2810
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Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: T
Toxic.
R-PHRASES: 45 46 20/21 25 36/38 43 48/23/24/25 62
May cause cancer. May cause heritable genetic damage. Also
harmful by inhalation and in contact with skin. Also toxic if
swallowed. Irritating to eyes and skin. May cause sensitization
by skin contact. Also toxic: danger of serious damage to health
by prolonged exposure through inhalation, in contact with skin
and if swallowed. Possible risk of impaired fertility.
S-PHRASES: 53 26 36/37 45
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of contact with
eyes, rinse immediately with plenty of water and seek medical
advice. Wear suitable protective clothing and gloves. In case
of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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