Material Safety Data Sheet
Date Printed: 19/OCT/2004
Date Updated: 12/MAR/2004
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
1 - Product and Company Information
Product Name ACETYLCHOLINE CHLORIDE, 98%
Product Number 135356
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
ACETYLCHOLINE CHLORIDE 60-31-1 200-468-8 None
Formula C7 H16 N O2 . Cl
Molecular Weight 181.66 AMU
Synonyms Acecholin * Acecoline *
2-Acetoxyethyltrimethylammonium chloride *
Acetylcholine chloride * O-Acetylcholine
chloride * Acetylcholine hydrochloride *
Acetylcholinium chloride *
chlorid * ACH chloride * Ammonium,
(2-hydroxyethyl)trimethyl-, chloride, acetate *
Arterocoline * Choline, chloride acetate *
chloride * (2-Hydroxyethyl)trimethylammonium
chloride acetat * Miochol * Ovisot * TL 1505
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Irritating to eyes, respiratory system and skin.
4 - First Aid Measures
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
Conditions of Storage: Keep tightly closed. Store in a cool dry
place. Store under nitrogen.
SPECIAL REQUIREMENTS: Very hygroscopic. Store under inert gas.
8 - Exposure Controls / Personal Protection
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
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Form: Fine crystals
Property Value At Temperature or Pressure
BP/BP Range N/A
MP/MP Range 148 掳C
Flash Point N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
Partition Coefficient N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Miscellaneous Data N/A
Solubility Solvent: 0.1 g/ml H2O clear, colorless
10 - Stability and Reactivity
Conditions to Avoid: Protect from moisture.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Hydrogen chloride gas.
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: FZ9800000
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Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Convulsions or effect on seizure threshold. Lungs,
Thorax, or Respiration:Other changes.
Remarks: Peripheral Nerve and Sensation:Spastic paralysis with
or without sensory change.
SIGNS AND SYMPTOMS OF EXPOSURE
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Vascular system. Heart. Central nervous system. Smooth muscle.
Skeletal muscle. Adrenal medulla.
12 - Ecological Information
No data available.
13 - Disposal Considerations
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
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14 - Transport Information
Non-hazardous for road transport.
Non-hazardous for sea transport.
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xi
Irritating to eyes, respiratory system and skin.
S-PHRASES: 26 36/37
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing and gloves.
16 - Other Information
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
For R&D use only. Not for drug, household or other uses.
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