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CAS

4733-39-5 7758-98-7 69-93-2 60-00-4

File Name: 4733-39-5_7758-98-7_69-93-2_60-00-4.asp

                                         OXIS International, Inc.
MATERIAL SAFETY DATA SHEET

SECTION I CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

BIOXYTECH?AOP-490TM Assay
Common Name/Trade Name:

Catalog Number(s): 21052

Date 22 Oct 2002

Manufacturer's Name: OXIS International, Inc.
6040 N. Cutter Circle, Suite 317
Portland, OR 97217-3935

Telephone Number: In Oregon (503) 283-3911
Toll Free (800) 547-3686
Facsimile (503) 283-4058


SECTION II 璈AZARDOUS COMPONENTS IDENTITY

Hazards identified with this product are associated with the following Assay Kit components:

Component: Hazardous Content:


R1 Name: Bathocuproine
Synonym: 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline
CAS# 4733-39-5
MF: C26H20N2

R2 Name: Cupric Sulfate
Synonym: Copper(II) Sulfate
CAS# 7758-98-7
MF: CuO4S

Uric Acid Standard Name: Uric Acid
Synonym: 8-hydroxyxanthine
CAS# 69-93-2
MF: C5H4N4O3

Stop Solution Name: Ethylenediaminetetraacetic Acid
Synonyms: EDTA; Edetic Acid
CAS# 60-00-4
MF: C10H16N2O8




MSDS21052 REV 12/02
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SECTION III - PHYSICAL AND CHEMICAL CHARACTERISTICS

R1:
Boiling point: Unknown Flash point: Unknown
Specific gravity: Unknown Flammable limits: Unknown
Vapor pressure: Unknown Extinguisher media: Unknown
Vapor density: Unknown Percent volatile: Unknown
Evaporation rate: Unknown Auto-ignition temperature: Unknown
Water solubility: Soluble
Reactivity in water N/A
Appearance: Liquid
Odor: Negligible odor

R2:
Boiling point: Unknown Flash point: Unknown
Specific gravity: Unknown Flammable limits: Unknown
Vapor pressure: Unknown Extinguisher media: Unknown
Vapor density: Unknown Percent volatile: Unknown
Evaporation rate: Unknown Auto-ignition temperature: Unknown
Water solubility: Soluble
Reactivity in water N/A
Appearance: Liquid
Odor: Negligible odor

Uric Acid Standard:
o
Melting point: >300 C Flash point: Unknown
Specific gravity: 1.89 (H2O = 1) Flammable limits: Unknown
Vapor pressure: Unknown Extinguisher media: Unknown
Vapor density: 5.8 Percent volatile: Unknown
Evaporation rate: Unknown Auto-ignition temperature: Unknown
Water solubility: Negligible
Reactivity in water N/A
Appearance: Solid, white crystals
Odor: Odorless

Stop Solution:
Boiling point: Unknown Flash point: Unknown
Specific gravity: Unknown Flammable limits: Unknown
Vapor pressure: Unknown Extinguisher media: Unknown
Vapor density: Unknown Percent volatile: Unknown
Evaporation rate: Unknown Auto-ignition temperature: Unknown
Water solubility: Soluble
Reactivity in water N/A
Appearance: Liquid
Odor: Negligible odor




MSDS21052 REV 12/02
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SECTION IV - REACTIVITY DATA AND STORAGE CONDITIONS

R1:
Stability: Stable
Conditions to avoid:
Storage conditions: Store reagents tightly capped in the dark at refrigerator
temperatures (2-8癈).
Hazardous decomposition products: Unknown
Hazardous polymerization: Will not occur

R2:
Stability: Stable
Conditions to avoid: On evaporation, may react violently with hydroxylamine,
magnesium.
Storage conditions: Store reagents tightly capped in the dark at refrigerator
temperatures (2-8癈).
Hazardous decomposition products: Oxides of copper and sulfur
Hazardous polymerization: Will not occur

Uric Acid Standard:
Stability: Stable
Conditions to avoid: None identified
Storage conditions: Store reagents tightly capped in the dark at refrigerator
temperatures (2-8癈).
Hazardous decomposition products: Hydrogen cyanide, nitrogen oxides, carbon monoxide,
carbon dioxide
Hazardous polymerization: Will not occur

Stop Solution:
Stability: Stable
Conditions to avoid:
Storage conditions: Store reagents tightly capped in the dark at refrigerator
temperatures (2-8癈).
Hazardous decomposition products: Nitrogen oxides, carbon monoxide, carbon dioxide
Hazardous polymerization: Will not occur


SECTION V - HEALTH HAZARD

R1:
Threshold limit value: None established
Toxicity data: Toxic. The toxicological properties of this material have not
been thoroughly investigated. Exercise due caution.

Health hazards: May be harmful by inhalation, ingestion, or skin absorption.
Acute effects:
First aid procedures: If swallowed, wash out mouth with water provided person is
conscious; seek immediate medical advice. In case of
contact with eyes or skin, remove contaminated
clothing/shoes, flush with plenty of water and seek medical
advice. If inhaled, expose to fresh air and seek medical
advice.

R2:
Threshold limit value: None established
Toxicity data: Toxic. The toxicological properties of this material have not
been thoroughly investigated. Exercise due caution.

Cupric sulfate is very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environments, may
impair fertility, and may cause harm to the unborn child.
Possible sensitizer. Target organs: liver, kidneys.
Terotogen. Reproductive hazard. Do not breath dust if
evaporated down to solid.
Health hazards: May be harmful by inhalation, ingestion, or skin absorption.
Acute effects:
First aid procedures: If swallowed, wash out mouth with water provided person is
conscious; seek immediate medical advice. In case of
contact with eyes or skin, remove contaminated
clothing/shoes, flush with plenty of water and seek medical
advice. If inhaled, expose to fresh air and seek medical
advice.
Uric Acid Standard:
Threshold limit value: None established

MSDS21052 REV 12/02
Page 3 of 4
Toxicity data: The toxicological properties of this material have not been
thoroughly investigated. Exercise due caution.
Health hazards: May be harmful by inhalation, ingestion, or skin absorption.
Acute effects: Inhalation can cause tightness and pain in chest, coughing,
difficulty breathing. May cause irritation on contact with eyes
or skin.
First aid procedures: If swallowed, wash out mouth with water provided person is
conscious; seek immediate medical advice. In case of
contact with eyes or skin, remove contaminated
clothing/shoes, flush with plenty of water and seek medical
advice. If inhaled, expose to fresh air and seek medical
advice.

Stop Solution:
Threshold limit value: None established
Toxicity data: The toxicological properties of this material have not been
thoroughly investigated. Exercise due caution.

Health hazards: Harmful if swallowed.
Acute effects: Irritating to eyes, skin, respiratory system.
First aid procedures: If swallowed, wash out mouth with water provided person is
conscious; seek immediate medical advice. In case of
contact with eyes or skin, remove contaminated
clothing/shoes, flush with plenty of water and seek medical
advice. If inhaled, expose to fresh air and seek medical
advice.

SECTION VI - SPECIAL PROTECTION INFORMATION

Respiratory protection: Suggested
Ventilation: Suggested
Mechanical: As required
Local Exhaust: As required
Other protective clothing or equipment: Laboratory coats, gloves and eye protection recommended.

SECTION VII - SPECIAL PRECAUTIONS AND SPILL/LEAK PROCEDURES

R1, R2, Stop Solution:
Steps to be taken in case material is released or
spilled: Wear protective clothing (laboratory coats, gloves, respirator,
and eye protection), wipe up spill with absorbant material
and dispose in appropriate container.
Clean up of spill site: Wash the spill site with soap and water.
Waste disposal methods: Dispose of waste in accordance with all Federal, State and
local regulations.

Uric Acid Standard:
Steps to be taken in case material is released or
spilled: Wear protective clothing (laboratory coats, gloves, respirator,
and eye protection), carefully sweep up and dispose in
appropriate container.
Clean up of spill site: Wash the spill site with soap and water.
Waste disposal methods: Dispose of waste in accordance with all Federal, State and
local regulations.



The information contained in this MSDS is believed to be correct to the best of our knowledge. However, we make no warranty,
expressed or implied, with respect to such information. The user should make an independent determination of the suitability of the
information based on all sources available and adopt appropriate safety precautions.




MSDS21052 REV 12/02
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