Conforms to 93/112/EC and ISO 11014-1
SAFETY DATA SHEET
Order Customer
Number
Number
Identification of the substance/preparation and of the company/undertaking
1.
5-Bromo-2'-deoxyuridine : 203806
Product name : Catalog #
: Manufactured by EMD Biosciences, Inc.
Supplier
10394 Pacific Center Court
Chemical formula N/A
:
San Diego, CA 92121
(858)450-5558/(800)854-3417
FAX: (858)453-3552
5-BrdU
:
Synonym
Emergency : Call Chemtrec庐
telephone number (800)424-9300 (within U.S.A.)
(703)527-3887 (outside U.S.A.)
Composition / information on ingredients
2.
: Substance
Substance/Preparation
Chemical name* CAS No. EC Number Symbol R-Phrases
1) 5-Bromo-2'-deoxyuridine 59-14-3 Not available. T R20/21/22, R46, R61
Hazards identification
3.
: Not applicable.
Physical/chemical hazards
: WARNING!
Human health hazards
MAY BE HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
MAY CAUSE BIRTH DEFECTS BASED ON ANIMAL DATA.
MAY CAUSE HERITABLE GENETIC EFFECTS BASED ON IN VITRO DATA.
First-aid measures
4.
First-Aid measures
: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Inhalation
Get medical attention.
: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
tight clothing such as a collar, tie, belt or waistband.
: In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Cold
Skin Contact
water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
Eye Contact
least 15 minutes. Cold water may be used. Get medical attention.
Effects and symptoms
Inhalation : Hazardous in case of inhalation.
: Hazardous in case of ingestion.
Ingestion
: Hazardous in case of skin contact (permeator).
Skin Contact
: Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in
Aggravating conditions
one or many human organs.
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203806
Catalog #
5. Fire-fighting measures
: May be combustible at high temperature.
Flammability of the Product
Extinguishing Media
: SMALL FIRE: Use DRY chemical powder.
Suitable
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Hazardous thermal (de)composition : These products are nitrogen oxides (NO, NO2...).
products
: Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.
Special fire-fighting procedures
: Be sure to use an approved/certified respirator or equivalent.
Protection of fire-fighters
Accidental release measures
6.
: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be
Personal precautions
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
Small Spill and Leak
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
Large Spill and Leak
water on the contaminated surface and allow to evacuate through the sanitary system
Handling and storage
7.
: Keep locked up. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,
Handling
evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not
breathe dust. Avoid contact with skin. Wear suitable protective clothing. In case of insufficient ventilation, wear
suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the
label. Keep away from incompatibles such as oxidizing agents.
: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 20掳C (68掳F).
Storage
Packaging materials
: Use original container.
Recommended use
Exposure controls/personal protection
8.
: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
Engineering measures
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure
to airborne contaminants below the exposure limit.
: Wash hands, forearms, and face thoroughly after handling compounds and before eating, smoking, using
Hygiene measures
lavatory, and at the end of day.
Ingredient Name Occupational Exposure Limits
1) 5-Bromo-2'-deoxyuridine Not available.
Personal protective equipment
: Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator
Respiratory system
when ventilation is inadequate.
: Lab coat.
Skin and body
: Gloves.
Hands
: Safety glasses.
Eyes
:
Protective Clothing
(Pictograms)
Physical and chemical properties
9.
: Solid. (Solid powder.)
Physical state
Color : White.
: 307.1 g/mole
Molecular Weight
: 191 to 194掳C (375.8 to 381.2掳F)
Melting Point
: Easily soluble in cold water.
Solubility
Flash point : Not available.
: Risks of explosion of the product in presence of mechanical impact: Not available.
Explosive properties
Risks of explosion of the product in presence of static discharge: Not available.
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Catalog #
10. Stability and reactivity
: The product is stable.
Stability
: Not available.
Conditions to avoid
: Reactive with oxidizing agents.
Materials to avoid
: These products are nitrogen oxides (NO, NO2...).
Hazardous Decomposition Products
11. Toxicological information
:
RTECS # YU7350000
Local effects
Skin irritation : Not available.
: Acute oral toxicity (LD50): 8400 mg/kg [Rat].
Acute toxicity
: Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in
Chronic toxicity
one or many human organs.
: Not available.
Other Toxic Effects on
Humans Hazardous in case of skin contact (permeator), of ingestion, of inhalation.
In vitro studies in mammal cells have shown mutagenic action. May cause congenital malformations in the
foetus.
Not available.
Specific effects
Carcinogenic effects : Not available.
Classified POSSIBLE for human. Mutagenic for mammalian germ and somatic cells based on in vitro studies.
Mutagenic effects :
Reproduction toxicity : Not available.
Classified POSSIBLE for human.
Teratogenic effects :
12. Ecological information
: Not available.
Ecotoxicity
: The products of degradation are less toxic than the product itself.
Toxicity of the Products of
Biodegradation
13. Disposal considerations
: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Methods of disposal; Waste of
residues; Contaminated packaging
14. Transport information
International transport regulations
Land - Road/Railway
: Not controlled under ADR (Europe).
ADR/RID Class
Sea
: Not controlled under IMDG.
IMDG Class
Air
: Not controlled under IATA.
IATA-DGR Class
Not applicable.
Special Provisions for
Transport
15. Regulatory information
EU Regulations
Hazard symbol(s) :
: Toxic
Classification
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203806
Catalog #
: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.
Risk Phrases
R46- May cause heritable genetic damage.
R61- May cause harm to the unborn child.
: S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
Safety Phrases
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
: - 5-Bromo-2'-deoxyuridine
Contains
: TSCA: No products were found.
U.S. Federal Regulations
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
: CLASS: Toxic.
HCS Classification
:
State Regulations
: CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
WHMIS (Canada)
No products were found.
16. Other information
Hazardous Material * 3 National Fire
Health
Fire Hazard
1
Information System 1 Protection
Fire Hazard
(U.S.A.) Association (U.S.A.) 3 0
Health Reactivity
0
Reactivity
Specific Hazard
E
Personal Protection
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its
subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be
used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Date of issue
Page: 4/4
3/12/2003.
203806
Catalog #
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