SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 05/11/2006
Date Updated: 02/05/2006
Version 1.3
Section 1 - Product and Company Information
Product Name TETRAMETHYLENE SULFONE, 99%
Product Number T22209
Brand ALDRICH
Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
SULFOLANE 126-33-0 No
Formula C4H8O2S
Synonyms Bondelane A * Bondolane A * Cyclic tetramethylene
sulfone * Cyclotetramethylene sulfone *
Dihydrobutadiene sulphone *
1,1-Dioxidetetrahydrothiofuran *
1,1-Dioxidetetrahydrothiophene * 1,1-Dioxothiolan
* Dioxothiolan * Sulfalone * Sulfolan * Sulfolane
* Sulpholane * Sulphoxaline *
Tetrahydrothiofen-1,1-dioxid (Czech) *
Tetrahydrothiophene dioxide * Tetrahydrothiophene
1,1-dioxide *
2,3,4,5-Tetrahydrothiophene-1,1-dioxide *
Tetramethylene sulfone * Thiacyclopentane dioxide
* Thiocyclopentane-1,1-dioxide *
Thiolane-1,1-dioxide * Thiophane dioxide *
Thiophan sulfone
RTECS Number: XN0700000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Harmful.
Harmful if swallowed. Irritating to eyes, respiratory system and
skin.
Target organ(s): Blood.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
Section 5 - Fire Fighting Measures
FLASH POINT
350.6 癋 177 癈 Method: closed cup
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe vapor. Avoid contact with eyes,
skin, and clothing.
STORAGE
Suitable: Keep tightly closed. Store in a cool dry place.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath.
PERSONAL PROTECTIVE EQUIPMENT
Other: Wear appropriate government approved respirator,
chemical-resistant gloves, safety goggles, other protective
clothing.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse.
Section 9 - Physical/Chemical Properties
ALDRICH - T22209 www.sigma-aldrich.com Page 2
Appearance Color: Colorless
Form: Crystals
Property Value At Temperature or Pressure
Molecular Weight 120.17 AMU
pH N/A
BP/BP Range 104 癈 0.2 mmHg
MP/MP Range 25 癈
Freezing Point N/A
Vapor Pressure N/A
Vapor Density 4.2 g/l
Saturated Vapor Conc. N/A
SG/Density 1.27 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content <2%
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point 350.6 癋 177 癈 Method: closed cup
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index 1.485
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Inhalation: May be harmful if inhaled.
Ingestion: Harmful if swallowed.
Multiple Routes: Vapor or mist is irritating to the eyes, mucous
membranes, and upper respiratory tract.
TARGET ORGAN(S) OR SYSTEM(S)
Blood.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
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Oral
Rat
1540 UL/KG
LD50
Skin
Rat
> 3800 mg/kg
LD50
Intraperitoneal
Rat
1600 MG/KG
LD50
Subcutaneous
Rat
1620 UL/KG
LD50
Oral
Mouse
1900 mg/kg
LD50
Intraperitoneal
Mouse
1250 MG/KG
LD50
Remarks: Biochemical:Metabolism (intermediary): Effect on
inflammation or mediation of inflammation.
Intravenous
Mouse
1080 MG/KG
LD50
Remarks: Behavioral:Convulsions or effect on seizure threshold.
Behavioral:Excitement.
Skin
Rabbit
3180 UL/KG
LD50
Remarks: Liver:Other changes. Kidney, Ureter, Bladder:Other
changes. Skin and Appendages:Skin: After systemic exposure:
Dermatitis, other
IRRITATION DATA
Eyes
Rabbit
253 mg
Remarks: Mild irritation effect
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
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Observe all federal, state, and local environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
Non-Hazardous for Air Transport: Non-hazardous for air
transport.
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: Xn
Indication of Danger: Harmful.
R: 22
Risk Statements: Harmful if swallowed.
S: 25-23
Safety Statements: Avoid contact with eyes. Do not breathe fumes.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Harmful.
Risk Statements: Harmful if swallowed. Irritating to eyes,
respiratory system and skin.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
US Statements: Target organ(s): Blood.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2006 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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