EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
1.) Identification of the substance/preparation and company
Product details
Trade name
Isobutyric anhydride
Use
chemical intermediates (including monomers)
Identification of the manufacturer / supplier
Address
Celanese Chemicals Europe GmbH
Frankfurter Stra遝 111
D-61476 Kronberg/Ts.
Information provided by / telephone
EHSA Europe FAX-Nr.: +49 (0) 208 693 2053
Emergency telephone +49 (0) 69-305 6418
number
2.) Composition / information on ingredients
Chemical characterization
2-Methylpropionic acid anhydride
Substance / product identification
CAS no. 97-72-3 Index no.
EINECS no. 202-603-6 ELINCS number :
Hazardous ingredients
Isobutyric acid
CAS no. 79-31-2
EINECS no. 201-195-7
Concentration <= 2 %-b.w. %-b.w.
Classification Xn;R21/22
Isobutyric anhydride
CAS no. 97-72-3
EINECS no. 202-603-6
Concentration >= 98 %-b.w. %-b.w.
Classification Xn;R21/22
C;R34
3.) Hazards possibilities
Hazard symbols
C Corrosive
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page: 1(7)
EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
R phrases
21/22 Harmful in contact with skin and if swallowed.
34 Causes burns.
4.) First aid measures
General Information
Remove contaminated, soaked clothing immediately and dispose of safely.
After inhalation
Ensure supply of fresh air. By continuous complaints consult a physician.
After skin contact
When in contact with the skin, clean with soap and water. If skin problems persist, seek medical advice.
After eye contact
In case of contact with eyes rinse thoroughly with plenty of water and seek medical advice.
After ingestion
When swallowed accidentally, do not induce vomiting, get medical help.
Advice to doctor
Hazards
Danger of irritation of the lungs
Treatment
In case of lung irritation, treat first with Auxiloson i.e. Pulmicort - Dosing aerosol (Auxiloson and Pulmicort
are registered Trade Marks). Treat symptomatically
5.) Fire-fighting measures
Suitable extinguishing media
Foam; Dry powder; Carbon dioxide; Water spray jet
Extinguishing media that must not be used for safety reasons
strong water jet
Special exposure hazards arising from the substance or preparation itself, its combustion products or
from resulting gases
In case of fires, hazardous combustion gases are formed: Carbon monoxide (CO). Carbon dioxide (CO2);
Combustion gases of organic materials must in principle be graded as inhalation poisons.
Special protective equipment for firefighting
Use self-contained breathing apparatus.
Other information (chapter 5.)
Cool endangered environment with water spray jet.
6.) Accidental release measures
Personal precautions
Avoid contact with eyes and skin.
Environmental precautions
Prevent spread over a wide area (e.g. by containment or oil barriers). Do not discharge into the
drains/surface waters/groundwater.
Methods for cleaning up/taking up
Pick up with absorbent material (eg sand, kieselgur, acid binder, universal binder, sawdust). Dispose of
contaminated material as prescribed
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page: 2(7)
EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
7.) Handling and storage
Handling
Advice on safe handling
Provide good ventilation of working area (local exhaust ventilation if necessary).
Advice on protection against fire and explosion
Keep away from sources of ignition - refrain from smoking. Take precautionary measures against static
charges. Emergency cooling must be provided for the eventuality of a fire in the vicinity.
Temperature class
T2
Use
Agrochemicals; Paints and Coatings; Pharmaceuticals; Perfumes & Flavors
Storage
Hints on storage assembly
Keep in cool, well ventilated place away from alkalies; Keep away from water.
Further information on storage conditions
Keep container tightly closed and dry.
8.) Exposure controls / personal protection
Ingredients with occupational exposure limits to be monitored
None
Personal protective equipment
Hand protection
Chemical resistant gloves
Appropriate Material PVC / Nitrile
Type Multiplus (Company COMASEC) or comparable article; or refer to glove
producer recommendation.
evaluation according to EN 374: level 6
Material thickness appr. 0,9 mm
Time for permeation > 480 min
Chemical resistant gloves
Appropriate Material Butyl rubber
Type Butylplus (Company COMASEC) or comparable article; or refer to glove
producer recommendation.
evaluation according to EN 374: level 6
Material thickness appr. 0,3 mm
Time for permeation > 480 min
Eye protection
Safety glasses
Skin protection
protective clothing
General protective and hygiene measures
Avoid contact with eyes and skin. Do not inhale vapours. Hold emergency shower available.
Hygenic measures
Do not eat, drink or smoke during work time. Remove soiled or soaked clothing immediately. Wash hands
before breaks and after work. Clean skin thoroughly after work; apply skin cream.
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page: 3(7)
EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
before breaks and after work. Clean skin thoroughly after work; apply skin cream.
9.) Physical and chemical properties
Appearance
Form Liquid
Colour colourless
Odour pungent
Safety data
Changes in physical state
type Melting point
Value -69 癈
Changes in physical state
type Boiling point
Value 183 - 187 癈
Flash point
Value 66 癈
Method DIN 51758
Ignition temperature
Value 375 癈
Density
Value 0,95 - 0,954 g/cm?br>
Reference temperature 20 癈
Solubility in water
Remarks Hydrolysed
Octanol/water partition coefficient (log Pow)
Value 1,2
Method calculated
10.) Stability and reactivity
Hazardous decomposition None
products
Hazardous reactions Reactions with water. Reactions with alkalies. Reactions with alcohols.
Thermal decomposition
Remarks No decomposition if used as prescribed.
11.) Toxicological information
Acute toxicity
Acute oral toxicity
LD50 265 mg/kg
Species rat
Remarks Details based on the acids.
Acute dermal toxicity
LD50 474 mg/kg
Species rabbit
Remarks The test was conducted with the corresponding organic acid.
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page: 4(7)
EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
Irritant/corrosive effects
Irritant effect on skin
evaluation corrosive
Irritant effect on eyes
evaluation corrosive
Other information
The substance has no mutagenic activity (Ames Test).
12.) Ecological information
Data on elimination ( persistence and degradability)
Biodegradability
Value 95
Duration of test 5 day(s)
Ecotoxic effects
Fish toxicity
LC50 100 - 1000 mg/l
Species goldfish
Daphnia toxicity
EC0 200 - 250 mg/l
Bacteria toxicity
EC0 500 mg/l
Duration of exposure 24 h
Method fermentation tube test
General information / ecology
Remarks The ecological data measured is for the hydrolysed product.
13.) Disposal considerations
Product
Disposal required in compliance with all waste management related local regulations.
The choice of the appropriate method of disposal depends on the product composition by the time of
disposal as well as the local statutes and possibilities for disposal.
Uncleaned packaging
Contaminated packaging should be emptied as far as possible and after appropriate cleansing may be
taken for reuse.
14.) Transport information
Land transport ADR/RID
UN number 2739
Technical name Butyric anhydride
Class 8
Packaging group III
Hazard no. 80
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page: 5(7)
EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
Inland waterways transport ADNR
Regulatory information ADNR: Container-Ship
UN number 2739
Technical name Butyric anhydride
Class 8
Packaging group III
Regulatory information ADNR: Tanker
Releasing Not permitted
Marine transport IMDG
UN number 2739
Propper shipping name Butyric anhydride
Class 8
Packaging group III
EmS 8-05 (Amdt 30-00)
F-A, S-B (Amdt 31-02)
Air transport ICAO/IATA
UN number 2739
Propper shipping name Butyric anhydride
Class 8
Packaging group III
Dispatch by post
Not permitted
15.) Regulatory information
Hazardous component(s) to be indicated on label
Isobutyric anhydride
Labelling in accordance with EC directives
The product is classified and labelled in accordance with EC Directive 67/548/EC.
Hazard symbols
C Corrosive
R phrases
21/22 Harmful in contact with skin and if swallowed.
34 Causes burns.
S phrases
26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
36/39 Wear suitable protective clothing and eye/face protection.
45 In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
Water Hazard Class (Ger.)
Class 1
Source Classification according to VwVwS, Annex 3
16.) Other information
Other information
Observe national and local legal requirements
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page: 6(7)
EC safety data sheet
Status: 12.02.2003
Trade name: Isobutyric anhydride
Date of printing : 19. 02.2003
subst.code: 6453 Version : 5 / Def
Product no.: ILIS005
R phrases
Isobutyric acid
21/22 Harmful in contact with skin and if swallowed.
Isobutyric anhydride
21/22 Harmful in contact with skin and if swallowed.
34 Causes burns.
This information is based on our present state of knowledge. It shall describe our products regarding safety
requirements and shall not be construed as a guarantee or statement of condition and/or quality.
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