SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 04/01/2008
Date Updated: 02/01/2006
Version 1.8
Section 1 - Product and Company Information
Product Name 2-HYDROXYETHYL METHACRYLATE, 97%
Product Number 128635
Brand ALDRICH
Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
2-HYDROXYETHYL METHACRYLATE 868-77-9 No
Ingredient Name CAS # Percent SARA 313
Stabilized with: None
DIETHYLENE GLYCOL MONOMETHACRYLATE 2351-43-1 3 No
METHACRYLIC ACID 79-41-4 <= 1.5 No
OTHER ESTER ADDUCTS None 0.7 No
ETHYLENE GLYCOL 107-21-1 0.25 Yes
4-METHOXYPHENOL 150-76-5 0.035 No
ETHYLENE OXIDE 75-21-8 0.001 Yes
Formula C6H10O3
Synonyms Ethylene glycol methacrylate * Ethylene glycol,
monomethacrylate * Glycol methacrylate * Glycol
monomethacrylate * Hydroxyethyl methacrylate *
beta-Hydroxyethyl methacrylate * 2-Hydroxyethyl
methacrylate * Mhoromer * Monomer MG-1 *
Monomethacrylic ether of ethylene glycol
RTECS Number: OZ4725000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Corrosive.
Harmful in contact with skin and if swallowed. Causes severe
burns. May cause sensitization by skin contact.
Readily absorbed through skin. Target organ(s): Kidneys. Liver.
HMIS RATING
HEALTH: 3*
FLAMMABILITY: 1
REACTIVITY: 1
NFPA RATING
HEALTH: 3
FLAMMABILITY: 1
REACTIVITY: 1
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
EXPLOSION HAZARDS
May explode when heated. Closed containers may rupture and
explode during runaway polymerization.
FLASH POINT
214 癋 101 癈 Method: closed cup
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Specific Method(s) of Fire Fighting: Use water spray to cool
fire-exposed containers.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Shut off all sources of ignition. Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
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disposal. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Avoid contact with eyes, skin, and clothing.
Avoid prolonged or repeated exposure. Do not breathe vapor.
STORAGE
Suitable: Keep tightly closed.
Store at 2-8癈
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Use respirators and components tested and approved
under appropriate government standards such as NIOSH (US) or CEN
(EU). Where risk assessment shows air-purifying respirators are
appropriate use a full-face respirator with multi-purpose
combination (US) or type ABEK (EN 14387) respirator cartridges as
a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator.
Other: Wear appropriate government approved respirator,
chemical-resistant gloves, safety goggles, other protective
clothing.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
Molecular Weight 130.14 AMU
pH N/A
BP/BP Range 67 癈 3.5 mmHg
MP/MP Range 46.0 - 50.0 癈
Freezing Point N/A
Vapor Pressure 0.01 mmHg 25 癈
Vapor Density 5 g/l
Saturated Vapor Conc. N/A
SG/Density 1.071 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point 214 癋 101 癈 Method: closed cup
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Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index 1.453
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Conditions to Avoid: Light. Heat. Moisture.
Materials to Avoid: Oxidizing agents, Free radical initiators,
Steel, Peroxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: May occur
Hazardous Polymerization Reactions: Loss of inhibitor
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: May be harmful if inhaled. Material is irritating to
mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
SENSITIZATION
Skin: May cause allergic skin reaction.
TARGET ORGAN(S) OR SYSTEM(S)
Heart. Liver. Kidneys.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
Oral
Rat
5050 mg/kg
LD50
Remarks: Behavioral:Coma.
Intraperitoneal
Rat
1250 MG/KG
LD50
Oral
Mouse
3275 mg/kg
LD50
Remarks: Behavioral:Coma.
Intraperitoneal
Mouse
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497 MG/KG
LD50
Oral
Guinea pig
4680 mg/kg
LD50
Remarks: Behavioral:Coma.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat Rat
Dose: 3062 MG/KG 3062 MG/KG
Route of Application: Oral Oral
Exposure Time: (35W PRE) (35W PRE)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetal death. Effects on Embryo or
Fetus: Fetal death. Effects on Fertility: Post-implantation
mortality (e.g., dead and/or resorbed implants per total number
of implants).
Species: Rat Rat
Dose: 3062 MG/KG 3062 MG/KG
Route of Application: Oral Oral
Exposure Time: (35W MALE) (35W MALE)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Effects on Fertility: Pre-implantation
mortality (e.g., reduction in number of implants per female;
total number of implants per corpora lutea). Effects on Embryo
or Fetus: Fetal death. Effects on Fertility: Pre-implantation
mortality (e.g., reduction in number of implants per female;
total number of implants per corpora lutea). Effects on Embryo
or Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Effects on Embryo or Fetus: Fetal death.
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
Non-Hazardous for Air Transport: Non-hazardous for air
transport.
Section 15 - Regulatory Information
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EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 36/37/38-43
Risk Statements: Irritating to eyes, respiratory system and
skin. May cause sensitization by skin contact.
S: 26-36/37
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing and gloves.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Corrosive.
Risk Statements: Harmful in contact with skin and if swallowed.
Causes severe burns. May cause sensitization by skin contact.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing, gloves, and eye/face protection.
In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
US Statements: Readily absorbed through skin. Target organ(s):
Kidneys. Liver.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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