MATERIAL
SAFETY
DATA SHEET
AGA GAS, INC. (216) 642-6600
Linde Gas LLC (216) 642-6600
Linde Gas LLC
6055 Box 94737 WOODS BLVD
P.O. Box 94737
P.O. ROCKSIDE No. 030
Cleveland, Ohio 44101
Cleveland, Ohio
P.O. BOX 94737 44101
www.us.lindegas.com
CLEVELAND, OH 44101-4737
www.us.lindegas.com June 3, 1994
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PENNGAS®- 2
(Ethylene Oxide Sterilant Mixture)
Pennsylvania Engineering Co.
1107-21 N. Howard Street
Philadelphia, PA 19123
Emergency Phone: 1-800-424-9300 (CHEMTREC)
(24 hours, toll free)
Phone Number for Additional Information:
(215) 627-3636
(Monday-Friday 9:00 a.m. - 5 00 p. m. EST)
Date: 6/1/94
2. COMPOSITION INFORMATION ON INGREDIENTS
(% CHEMICAL COMPONENTS BY WEIGHT)
Ingredient / CAS Number Concentration
Ethylene Oxicle 10%
(75-21 -8)
Hydrochlorofluorocarbons (Trade Secret) 90%
(See Section 8 for Exposure Guidelines)
Information contained in this material safety data sheet is offered without charge for use by technically qualified personnel at their discretion and
risk. All statements, technical information and recommendations contained herein are based on tests and data which we believe to be reliable, but
the accuracy or completeness thereof is not guaranteed and no warranty of any kind is made with respect thereto. This information is not intended
as a license to operate under or a recommendation to practice or infringe any patent of this Company or others covering any process, composition
of matter or use.
Since the Company shall have no control of the use of the product described herein, the Company assumes no liability for loss or damage incurred
from the proper or improper use of such product.
Penngas® - 2
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Sweet smelling clear compressed gas. High concentrations in immecliate area can
reduce oxygen and result in dizziness, unconsciousness,. and death due to asphyxiation.
Acute effects from inhalation of ethylene oxide vapors include respiratory irritation and
lung injury, headache, nausea, vomiting, diarrhea. shortness of breath, and cyanosis
(blue or purple coloring of skin). Exposure to ethylene oxidie is also suspected to be
associated with the occurrence of cancer, reproductive effects, neurotoxicity, and
sensitization. Eye exposure to liquid can cause eye irritation and injury to the cornea, and
frostbite. Skin contact can result in frostbite, severe irritation, and blistering of the skin
upon prolonged or continued contact. Can decompose at high temperatures yielding
toxic gases.
POTENTIAL HEALTH EFFECTS:
EYE: Mixture can cause eye irritation ancl injury to the cornea.
SKIN: Although exposure in liquid from is unlilkely to its low boiling point, exposure in liquicl from can cause frostbite ancl
sever irritation and blistering of the skin upon prolonged or continuccl contact.
INGESTION: Ingestion is an unlikely route of exposure clue to its low boiling point. See section 1 1, toxicological
information, for additional information.
INHALATION: Hydrochlorofluorocarbons are low in inhalation toxicity in concentrations as high as 4% (40,000 ppm).
Acute effects from inhalation of ethylene oxicle vapors inclucle respiratory irritation and lung injury, headache, nausea,
vomiting, diarrhea, shortness of breath, and cyanosis (blue or purple coloring of skin). Exposure to ethylene oxide is
suspectecl to be associated with the occurrence of cancer, reproductive effects, neurotoxicity, ancl sensitization.
SIGNS AND SYMPTOMS OF EXPOSURE: The early effects of acute overexposure to ethylene oxide are nausea ancl
vomiting, heaclache, ancl irritation of the eyes ancl respiratory
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Penngas® - 2
passages. The patient may notice a “peculiar taste� in the mouth. Delayed effects can include pulmonary edema,
drowsiness, weakness, and incoordinarion. When oxygen levels in air are reduced, symptoms of asphyxiation will occur:
loss of coordination, increased pulse rate, and deeper respiration. Studies suggest that blood cell changes and increase
in chromosomal aberrations, and spontaneous abortion may also be casually related to acute overexposure to ethylene
oxide. Skin contact with liquid or gaseous ethylene oxide causes characteristic burns and possibly even all allergic-type
sensitization. Contact with the mixture may cause frostbite because of rapid evaporation. Mixture can cause eye irritation
and injury to the cornea. Animal studies suggest that high hydrochlorofluorocarbon concentrations may reduce heart
efficiency and may cause cardiac sensitization to epinephrine.
CHRONIC EFFECTS / CARCINOGENICITY: Ethylene oxide is listed by IARC as a known human carcinogen (Group 1).
Exposure to ethylene oxide is also suspected to be associated with the occurrence of reproductive effects, neuroroxicity.
and sensitization.
FOR A COMPLETE DISCUSSION OF TllE TOXICITY OF THIS PRODUCT, PLEASE REFER TO SECTION 11.
4. FIRST AID MEASURES
EYE: Wash eyes immediately with large amounts of water, lifting the lower and upper eyelids. Get medical attention
immediately. Contact lenses should not be worn when woking with this chemical.
SKIN: Wash the contaminated slcin with water. If the mixture soaks through clothing, especially shoes, remove the
clothing and shoes immediately and wash the skin with water using an emergency deluge shower. Get medical attention
immediately. Thoroughly wash contaminated clothing before reusing. Immediately bathe (do not rub) any frostbite with
lukewarm (not hot) water. In the absence of water, cover with soft wool or other suitable material. Contact a physician for
any low temperature burns from liquid contact.
INGESTION: Although unlikely to be ingested due to its low boiling point, if ingested. give the person, if conscious, large
quantities of water immediately. Do not malce an unconscious person vomit. Get medical attention immediately.
INHALATION: If overcome, move the exposed person to fresh air at once. If breathing has stopped, perform
cardiopulmonary resuscitation. Keep the affected person warm and at rest. Get medical attention immediately.
NOTE TO PHYSICIAN: Do not give epinephrine (adrenaline).
*Various Government Agencies (i.e. Department of Transportation, Occupational Safety and Health Administration, Food and Drug Administration
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and others) may have specific regulations concerning the transportation, handling, storage or use of this product which will not be reflected in this
data sheet. The customer should review these regulations to ensure that he is in full compliance.
Penngas® - 2
5. FIRE FIGHTING MEASURES
FLAMMABLE PROPERTIES: Penngas® - 2 is approved by the U.S. Dept. of Transportation as a sreen label,
non-flammable, non-explosive. non-poisonous formula.
FLASH POINT: Not applicable.
FLASH POINT METHOD: Not applicable.
AUTOIGNITION TEMPERATURE: Not applicable.
UPPER FLAME LIMIT (Volume % in air): 23.5% (E-681 Spark Ignition)
22.0% (E-681 Fused Wire Ignition)
LOWER FLAME LIMIT (Volume % in air): 22.7% (E-681 Spark Ignition)
20/5% (E-681 Fused Wire Ignition)
FLAME PROPAGATION RATE (Solids): Not applicable.
OSHA FLAMMABILITY CLASS: Not flammable.
EXTINGUISHING MEDIA: Use media appropriate for surrounding fire.
UNUSUAL FIRE AND EXPLOSION HAZARDS: Container may rupture clue to heat of fire. No part of a container should
be subjected to a temperature higher than 52ÂşC (approximately 125ÂşF). Containers are designed to vent contents when
they are exposed to elevated temperatures. Avoid exposing stored Penngas® -2T. Sterilant Mixture to heat or sources of
ignition.
SPECIAL FlREFIGHTING PRECAUTIONS / INSTRUCTIONS: Evacuate all personnel from danger area. Immediately
cool containers with water spray from maximum distance until cool. Use self-contained breathing apparatus operated in
the pressure demand mocle and appropriate protective clothing. Stop flow of gas if without risk, while continuing cooling
water spray. Remove all containers from area of fire without risK.
6. ACCIDENTAL RELEASE MEASURES
Product is a compressed gas. The area should be evacuated at once and re-entered only after the area has been
thoroughly ventilated. Persons not wearing appropriate protective equipment should be restricted from areas of spills or
leaks until thoroughly ventilated.
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Penngas® - 2
7. HANDLING AND STORAGE
Store cylinders in a cool, well-ventilated area. away from heat. Do not store over 1 40ÂşF (Longer shelf life if stored under
1 00ÂşF). Store cylinclers upnght in a raclc or wall to prevent tipping. Cylinclers should not be subjected to rough handling
or mechanical shock such as dripping, bumping, dragging, or sliding. Do not use rope slings. hooks tongs, similar
devices to unload cylinders. Transport cylinders using hand truc, fork truck, or other devices to which the cylinder can be
firmly secured.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
RESPIRATORYPROTECTION: Respirators should be selectecl in conformance with 29 C.F.R ~ 1910.1047 (g). If
air-purifying respirators are worn. they must be approved by the National Institute for Occupational Safety and Health
(NIOSH) for use with ethylene oxide. For effective protection, respirators must fit the face and heacl snugly. Respirators
should not be loosened for removed in woric situations where their use is required. Ethylene oxide does not have a
detectable odor except at levels well above the permissible exposure limit; above approximately 700 ppm If ethylene
oxicie can be smelled while wearing a respirator, proceed immediately to fresh air If breathing becomes difficult while
wearing a respirator, inform your employer.
SKIN PROTECTION: Impermeable clothing, gloves, a face shield or other appropriate protecffve clothing should be
worn to prevent skin contact. Clean garments should be provided as necessary to assure that the clothing provides
adequate protection. Replace or repair protective clothing that has become torn or otherwisedlamaged. Liquid mixture
should never be allowed to remain on the skin. Clothing and shoes which are not impermeable to the mixture should not
be allowed to become contaminatdl. If contamination occurs, clothing should be promptly removed and decontaminated.
Contaminated leather shoes should be discarded. Once the mixture penetrates shoes or other leather articles, they
should not be worn again.
EYE PROTECTION: Safety goggles must be worn in areas where mixture may contact eyes. In addition, contact lenses
should not be worn in areas where eye contact with mixture can occur.
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Penngas® - 2
EXPOSURE GUIDELINE(S):
Ingredient / CAS Number Exposure Limits Concentration
Ethylene Oxide
(75-2 1 -8) OSHA: PEL I ppm (v/v)
(8-hour TWA)
Excursion
Limit: 5 ppm (v/v)
(I 5 minute)
ACGIH: TLV: I ppm (v/v)
(8-hour TWA)
Hydrochlorofluorocarbons 90%
(Trade Secret)
OSHA: N.E
ACGIH: N.E
N.E. = not established for the hydrochlorofluorocarbon mixture. Both of the hydrochlorofluorocarbons has an OSHA PEL
and an ACGIH, or a PAFT TLV of 1,000 ppm.
ENGINEERING CONTROLS: General and local ventilation systems should be used to maintain airborne levels of
ethylene oxide below applicable exposure limits. Eyewash stations, emergency deluge showers and washing facilities
should be available in all areas where ethylene oxide is used or handled. Do not eat, drink, or smoke in any work area.
See 29 C.F.R § 1910.1047 for additional information concerning the use of ethylene oxide in hospitals and health care
facilities.
9. PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE: Colorless compressec! ~gas
ODOR Slight ethereal
BOILING POINT: -15.9ÂşF
VAPOR PRESSURE: 61 psig at 70ÂşF
VAPOR DENSITY: (air = I ) 3.5
SOLUBILITY IN WATER: Ethylene Oxide: Complete.
Hydroclorofluorocarbons: Slight
SPECIFIC GRAVITY: 1.28
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Penngas® - 2
FREEZING POINT: N/A
pH: no pH
% VOLATILE: 100 %
10. STABILITY AND REACTIVITY
STABILITY: (CONDITIONS TO AVOID) Ethylene oxide will polymerize violently if contaminated with aqueous alkalies,
amines, mineral acids. metal chlorides. or metal oxides. Ethylene oxide will violently clecompose at temperatures above
800ÂşF. Hydrochlorofluorocarbons may decompose at very high temperatures yielding toxic gases.
INCOMPATIBILITY: (SPECIFIC MATERIALS TO AVOID) Ethylene oxicle reacts with active catalysts which can promote
explosive, exothermic polymerization. Such substances include potassium; anhydrous chlorides of tin, aluminum and iron;
alcohols; mercaptans; copper; pure oxides of iron or aluminum; magnesium perchlorate; ancl acids and bases such as
sodium and potassium hydroxide. Hydrochloroflourocarbons are incompatible with strong oxidants, and chemically active
metals such as alkali metals, alkaline earth metals, powered aluminum, magnesium and zinc (may cause exothermic
reaction).
HAZARDOUS DECOMPOSITION PRODUCTS: Ethylene oidle: Carbon monoxide and carbon dioxide.
Hydrochlorofluorocarbons: Halogens, halogen acids. carbon dioxide, carbon monoxide, and possibly carbonyl halides
such as phosgene.
HAZARDOUS POLYMERIZATION: May occur.
11. TOXICOLOGICAL INFORMATION:
INGESTION: Ingestion is an unlikely route of exposure due to its low boiling point. Should ingestion occur, discomfort in
the gastrointenstinal tract would result from the rapid evaporation of the liquid. Frostbite could also occur Ingestion of
ethylene oxide can cause anemia, gastrointestinal irritation, and liver. kidney, and adrenal gland effects.
SKIN AND EYE: Mixture can cause eye irritation ancl injury to the cornea. frostbite, sever irritation, ancl blistering of the
skin upon prolonged or confinecl contact.
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Penngas® - 2
CHRONIC EFFECTS / CARCINOGENICITY: Ethylene oxicie has been shown to cause cancer in laboratory animals and
has been associated with higher incidences of cancer in humans. Adverse reproductive effects and chromosome clamage
may also occur from ethylene oxide exposure. Exposure to ethylene oxide in studies is associated with an increased
incidence of cancer in laboratory animals (leukemia, stomach, brain), mutation in offspring in animals, and resorptions
and spontaneous abortions in animals and human populations, respectively. Findings in humans and experimental
animals exposed to airborne concentrations of ethylene oxide also indicate damage to the genetic material (DNA). These
include hemoglobin alkylation, unscheduled DNA synthesis. sister chromatid exchange chromosomal aberration, and
functional sperm abnormalities.
Ethylene oxide is listed as a cancer/reproductive hazard uncler OSHA; a suspectecl human carcinogen by ACGIH.; an
anticipated human carcinogen by NTP and a known human carcinogen (Group 1 ) by IARC.
Hydrocholorfluorocarbons are low in inhalation toxicity in animals at concentrations of up to 4% (40,000 ppm); however,
when oxygen levels in air are reduced to 12- 1 4% by displacement, symptoms of asphyxiation, loss of coordination.
increased pulse rate and deeper respiration will occur. At high levels, cardiac arrhythmia may occur. Many
chlorofluorocarbon and hydrochlorofluorocarbon gases have been demonstrated to induce cardiac sensitization to
epinephrine. A two-year inhalation study of one of the hydrochlorofluorocarbons indicated a slight increase in salivary
gland tumors (rat) at the highest level of exposure tested (50,000 ppm). There was no observable results in rats at
exposure levels of 1000 ppm and 10,000 ppm, and none in mice at any dose level
12. ECOLOGICAL INFORMATION
ECOTOXICOLOGICAL INFORMATION: N/A
DISTRIBUTION: N/A
CHEMICAL FATE INFORMATION: No appreciable bioconcentration is expected in the envirornment.
13. DISPOSAL CONSIDERATIONS
Do not contaminate water, food or feed by storage or disposal.
Pesticide Disposal: Waste should not be discarded or released to the environment, but returned in cylinders with valves
closed and plugs inserrecl.
Container Disposal: Return empty cylinders for reuse wirh valves closed and plugs inserted
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Penngas® - 2
Pesticide wastes are toxic. Improper disposal of excess pesticicle, spray mixture, or rinsate is a violation of Federal law. If
these wastes cannot be clisposedl of by use according to label instructions, contact your State Pesticide or Environmental
Control Agency or The Hazardous Waste representatives of the nearest EPA Regional Office for guidance.
14. TRANSPORT INFORMATI0N
Either of the following shipping descriptions may be usedl:
Liquefied gases, n.o.s. (ethylene oxide, chlorofluorohydrocarbon gases)
2.2 UN 1956
Liquefid gases, n.o.s. (ethylene oxide, chlorofluorohydrocarbon gases).
2.2 UN 3163
15. REGULATORY INFORMATION
OSHA: OSHA CHEMICAL SPECIFIC STANDARD FOR ETHYLENE OXIDE.
29 C.F.R § 1910.1047.
Ethylene oxide is a highly hazardous chemical for the purposes of process safety
management under 29 C.F.R § 1910.1 1 9.
CERCLA, SUPERFUND, 40 C.F.R. §§ 117, 302: Releases of ethylene oxide are reportable under Section 103 of
CERCLA. 40 C R F. § 302. The reportable qluantity (RQ is 10 pounds (4.54 kg). The threshold planning quantity is 1,000
pounds. 40 C.F.R. § 355.
SARA § 311/312 HAZARD CATEGORY:
1 ) Sudden release of pressure.
2) Toxicity: Immediate (Acute)
Delayed (Chronic)
SARA § 313 INFORMATION: Ethylene oxide is subject to the requirements of Section 313 of Title 111 of the Superfund
Amendments and Reauthorization Act of 1986 ancl 40 C. F. R Part 372.
TOXIC SUBSTANCES CONTROL ACT (TSCA): The ingredients of this procluct are all included on the TSCA Inventory.
CALIFORNIA PREPOSITION 65: Ethylene oxide is a chemical known to cause cancer and female reproductive toxicity
for the purposes of California Proposition 65.-N
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