One Lambda, Inc.
21001 Kittridge Street, Canoga Park, CA 91303-2801 USA Tel: +1 (818) 702-0042 Fax: +1 (818) 702-6904 WEB:www.onelambda.com
MATERIAL SAFETY DATA SHEET
FluoroQuenchTM Stain/Quench Reagents
Material Safety Data Sheet (MSDS) produced in compliance with 29 CFR 1910.1200 and EC Directive 91/155/EEC
1. Identification of the Substance/Preparation and the Company:
FluoroQuenchTM Stain/Quench Reagent
Product Name:
Company: One Lambda, Inc. 21001 Kittridge Street
Canoga Park, CA 91303-2801 USA
Regional Representation: One Lambda Europe
Emergency Telephone No.: +1 818.702.0042
Synonyms: None.
EUROPEAN
Medical Device Safety Service GmbH Schiffgraben 41 D-30175 Hannover Germany
AUTHORIZED REPRESENTATIVE:
2. Hazards Identification:
May cause eye and skin irritation. May cause skin sensitization.
May alter genetic material. No explosive or fire hazards.
EU Preparation Classification (1999/45/EC): Harmful (Xn) R43, R68
OSHA Hazard Classification (29CFR1910.1200): Irritant, Sensitizer
3. Composition/Information on Ingredients:
Chemical CAS / EINECS Number Amount EU Classification (67/548/EEC)
(gm%)
Disodium 6381-92-6 1-5% Xi R36/37/38
Ethylenediaminetetraacetate
dihydrate
Glyoxal (FQ-AO/EB Plus) 107-22-2 / 203-474-9 1-2% Xn R20,R68,R43,R36/38
Sodium Azide 26628-22-8 / 232-731-8 <0.1% N, T+, R28, R32, R50/53
See Section 16 for further information on EU Classification
All other components non-hazardous as defined by the US OSHA Hazard Communication Regulation (29 CFR 1910.1200),
Canada鈥檚 WHMIS regulations and the EU Directives on the classification and labelling of dangerous substances and preparation.
This product does contain animal source material and should be handled following routine biosafety precautions.
4. First-Aid Measures:
In case of eye contact: Immediately flush eyes with large amounts of water. Seek medical attention.
In case of skin contact: Immediately wash skin with soap and large amounts of water. Seek medical attention if irritation or other
symptoms develop. Launder contaminated clothing before re-use.
In case of ingestion: If the person is conscious, immediately flush mouth with water. Then, have person drink one or two glasses of
water. Get immediate medical attention.
In case of inhalation: Remove person to fresh air. If person is not breathing, give artificial respiration. If person鈥檚 breathing is
difficult, give oxygen. Seek medical attention.
5. Fire-Fighting Measures:
Extinguishing media: Use any media that is appropriate for the surrounding fire.
Extinguishing media NOT to use: None known.
Special fire-fighting equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and
eyes.
Unusual Fire and Explosion Hazards: None
Hazardous Combustion Products: Emits toxic fumes and dense black smoke under fire conditions.
Rev. 6: 2007/09 Page 1 of 4
FQECMSDS_EN.doc
One Lambda, Inc.
21001 Kittridge Street, Canoga Park, CA 91303-2801 USA Tel: +1 (818) 702-0042 Fax: +1 (818) 702-6904 WEB:www.onelambda.com
MATERIAL SAFETY DATA SHEET
6. Accidental Release Measure:
Personal precautions: Wear protective equipment including rubber boots and heavy rubber gloves.
Environmental precautions: Do not wash down drains. If this occurs, flush drains with large amount of water.
Cleaning method: Absorb with inert absorbent material. Collect and place in an appropriate waste disposal container. Wash
residual traces with a mild detergent solution, followed by a disinfectant. Keep in a closed container.
7. Handling and Storage:
Handling: Wear laboratory coat, safety glasses and chemically resistant gloves. Use good laboratory practices. Avoid contact with
eyes, skin and clothing. Wash hands thoroughly after handling.
Storage: Keep tightly closed. Store in a cool dry place.
8. Exposure Controls/Personal Protection:
Chemical Occupational Exposure Limits/Source
Disodium None Established
Ethylenediaminetetraacetate
dihydrate
Glyoxal 0.1 mg/m3 TWA (inhalable fraction and vapor) ACGIH TLV
Sodium Azide 0.29 mg/m3 Ceiling / ACGIH TLV
0.2 mg/m3 / DFG MAK
0.1mg/m3 TWA skin / UK WEL
0.3 mg/m3 / UK STEL
Engineering Controls: General laboratory ventilation should be adequate for normal use.
Respiratory protection: None are normally needed.
Hand protection: Wear chemically resistant gloves.
Eye protection: Laboratory safety goggles are recommended.
Skin protection: Wear laboratory coat.
Other Controls: Safety shower and eye bath are recommended.
9. Physical and Chemical Properties:
Form: Liquid. Appearance: Opaque
Color: Deep brown Odor: Odorless.
Solubility: Soluble in water.
To the best of our knowledge, the chemical and physical properties have not been thoroughly investigated.
10. Stability and Reactivity:
Conditions to avoid: Heat.
Materials to avoid: Avoid contact with strong oxidizers, metals, acids, and acid chlorides.
Hazardous decomposition products: Nitrogen oxides, hydrogen bromide, carbon oxides and hydrocarbons. Sodium azide can
react with heavy metals to form explosive azides. Reaction with acids may generate toxic gas.
11. Toxicological Information:
Acute Effects of Overexposure:
Inhalation: Inhalation of mists may cause respiratory irritation.
Ingestion: May cause irritation of the intestinal tract and other adverse effects. Contains <0.1% sodium azide. Ingestion of sodium
azide has been reported to cause shortness of breath, nausea, vomiting, restlessness, diarrhea, lowering of blood pressure
(hypotension), and collapse.
Skin Contact: May cause irritation. Prolonged and extensive skin contact may result in absorption with systemic symptoms similar
to ingestion. Repeated skin contact may cause allergic skin reaction (sensitization).
Eye Contact: May cause irritation.
Chronic Effects of Overexposure: Sodium azide and glyoxal are suspected of altering genetic material.
Carcinogen or Suspected Carcinogen: None of the components are listed as a carcinogen or suspected carcinogen.
Medical Conditions Aggravated by Exposure: Pre-existing skin conditions.
Rev. 6: 2007/09 Page 2 of 4
FQECMSDS_EN.doc
One Lambda, Inc.
21001 Kittridge Street, Canoga Park, CA 91303-2801 USA Tel: +1 (818) 702-0042 Fax: +1 (818) 702-6904 WEB:www.onelambda.com
MATERIAL SAFETY DATA SHEET
Acute Toxicity Values:
Disodium Ethylenediaminetetraacetate dihydrate: LD50 oral rat: 2000 mg/kg
Glyoxal: LD50 oral rat: 1400 mg/kg; LD50 dermal rabbit: 10 g/kg; LC50 inhalation rat 2410-2470 mg/m3/4 hr
Sodium Azide: LD50 oral rat: 27 mg/kg; LD50 dermal rabbit: 20 mg/kg
To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
12. Ecological Information:
Sodium Azide: LC50/96 hr daphnia pulex 4.2 mg/L; LC50/96 hr rainbow trout 0.8-1.6 mg/L
13. Disposal Considerations:
Dispose of with biohazardous waste.
Dispose of in accordance with all federal, state, and local environmental regulations.
14. Transport Information:
Not regulated for transport in accordance with US DOT, ICAO, IMDG, Canadian TDG or ADR.
15. Regulatory Information:
U.S. TSCA Inventory: Medical devices are not subject to TSCA.
U.S. SARA Title III:
鈥? Section 311/312 Hazard Categories: Acute Health, Chronic Health
鈥? Section 313 (40 CFR 372): Not listed.
California Proposition 65: This product does not contain any chemicals currently on the California list of known carcinogens and
reproductive toxins.
Canada WHMIS: Medical devices are not subject to WHMIS.
Canadian Environmental Protection Act: Medical devices are not subject to CEPA.
European Inventory of Existing Commercial Chemical Substances: Medical devices are not subject to notification.
EU Labeling (for FQ-AO/EB Plus):
Contains glyoxal
R43 May cause sensitization by skin contact.
R68 Possible risk of irreversible effects.
S36/37 Wear suitable protective clothing and
gloves.
Harmful
Australia: Medical devices are not subject to notification.
Japan: Medical devices are not subject to notification.
Korea: Medical devices are not subject to notification.
Philippines: Medical devices are not subject to notification.
China: Medical devices are not subject to notification.
16. Other Information:
NFPA Rating: Fire: 0 Health: 2 Reactivity: 0
EU Classes and Risk Phrases for Reference (See Sections 2 and 3):
N - Dangerous for the environment
T+ - Very toxic
Xi 鈥? Irritant
Xn 鈥? Harmful
R20 鈥? Harmful by inhalation.
R28 - Very toxic if swallowed.
R32 - Contact with acids liberates very toxic gas.
R36/38 鈥? Irritating to eyes and skin.
R36/37/38 鈥? Irritating to eyes, respiratory system and skin.
R43 鈥? May cause sensitization by skin contact.
R50/53 - Very toxic to aquatic organisms, may cause long-term effects in the aquatic environment.
R68 鈥? Possible risk of irreversible effects.
Rev. 6: 2007/09 Page 3 of 4
FQECMSDS_EN.doc
One Lambda, Inc.
21001 Kittridge Street, Canoga Park, CA 91303-2801 USA Tel: +1 (818) 702-0042 Fax: +1 (818) 702-6904 WEB:www.onelambda.com
MATERIAL SAFETY DATA SHEET
Note: If substantial amounts of reagents containing Sodium Azide are disposed of in plumbing systems, Sodium Azide may build up
and form metal azides with copper or lead. This may produce a potential explosion hazard. See "Safety Management No. CDC-22
(United States Center for Disease Control) Decontamination of Laboratory Sink Drains to remove Azide Salts".
REVISION HISTORY
Revision Date Revision Description
6 2007/09 Format change 鈥? affects all sections.
Date of issue: 9/21/07
The above information is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. One Lambda
shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
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