ETHYL ACETATE 09/06/2005 05:19 PM
MSDS Number: E2850 * * * * * Effective Date: 08/10/04 * * * * * Supercedes: 11/12/01
ETHYL ACETATE
1. Product Identification
Synonyms: Acetic acid ethyl ester; Acetic ether; Acetoxyethane; Ethyl Acetic Ester; Ethyl ethanoate
CAS No.: 141-78-6
Molecular Weight: 88
Chemical Formula: CH3COOC2H5
Product Codes:
J.T. Baker: 5541, 9260, 9276, 9278, 9279, 9280, 9282, 9284
Mallinckrodt: 3427, 3432, 3442, 4988, 4992, 4996, H078, V553
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------
Ethyl Acetate 141-78-6 99 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED OR INHALED. AFFECTS CENTRAL NERVOUS SYSTEM.
CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
SAF-T-DATA (tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate (Life)
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation can cause severe irritation of mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis,
shortness of breath, headache, nausea and vomiting. High concentrations may cause lung damage. An irritant to the nose, throat, and upper respiratory tract.
Exposure to high concentrations have a narcotic effect and may cause liver and kidney damage.
Ingestion:
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain. Repeated or prolonged contact with the skin has a defatting effect and may cause dryness,
cracking, and possibly dermatitis.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
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ETHYL ACETATE 09/06/2005 05:19 PM
Chronic overexposure may cause anemia with leukocytosis (transient increase in the white blood cell count) and damage to the liver and kidneys.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney or respiratory function may be more susceptible to the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing
before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: -4C (25F) CC
Autoignition temperature: 426C (799F)
Flammable limits in air % by volume:
lel: 2.0; uel: 11.5
Flammable Liquid and Vapor! Contact with strong oxidizers may cause fire.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Sealed containers may rupture when heated. Sensitive to static
discharge.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide. Water may be ineffective. Water spray may be used to keep fire exposed containers cool.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand
or other positive pressure mode. Water may be used to flush spills away from exposures and to dilute spills to non-flammable mixtures. Vapors can flow along
surfaces to distant ignition source and flash back.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep
unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an
appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible
materials, such as saw dust. Do not flush to sewer! US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable
quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802. If a leak or spill has not ignited, use water spray to disperse
the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures.
J. T. Baker SOLUSORB庐 solvent adsorbent is recommended for spills of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage
is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No
Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous when empty since
they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL): 400 ppm (TWA)
-ACGIH Threshold Limit Value (TLV): 400 ppm (TWA), A4 - Not classifiable as a human carcinogen.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally
preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a full facepiece respirator with organic vapor cartridge may be worn up to 50 times the
exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or
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ETHYL ACETATE 09/06/2005 05:19 PM
instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear liquid.
Odor:
Fruity odor.
Solubility:
1 ml/10ml water @ 25C
Specific Gravity:
0.902 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
77C (171F)
Melting Point:
-83C (-117F)
Vapor Density (Air=1):
3.0
Vapor Pressure (mm Hg):
76 @ 20C (68F)
Evaporation Rate (BuAc=1):
6
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Heat will contribute to instability. Slowly decomposed by moisture.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Avoid heat, flame and other sources of ignition. Contact with nitrates, strong oxidizers, strong alkalis, or strong acids may cause fire and explosions. Will attack
some forms of plastic, rubber, and coatings.
Conditions to Avoid:
No information found.
11. Toxicological Information
Inhalation rat LC50: 200 gm/m3; oral rat LD50: 5620 mg/kg; Skin rabbit LD50: > 20 ml/kg. Investigated as a mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Ethyl Acetate (141-78-6) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this material may leach into groundwater. When released into the soil, this material may evaporate to a moderate extent. When
released into water, this material may biodegrade to a moderate extent. When released to water, this material is expected to quickly evaporate. When released into
the water, this material is expected to have a half-life of less than 1 day. This material has a log octanol-water partition coefficient of less than 3.0. This material
is not expected to significantly bioaccumulate. When released into the air, this material is expected to be readily degraded by reaction with photochemically
produced hydroxyl radicals. When released into the air, this material may be moderately degraded by photolysis. When released into the air, this material is
expected to have a half-life between 1 and 10 days.
Environmental Toxicity:
This material is not expected to be toxic to aquatic life.
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ETHYL ACETATE 09/06/2005 05:19 PM
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved waste facility. Processing, use or
contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ETHYL ACETATE
Hazard Class: 3
UN/NA: UN1173
Packing Group: II
Information reported for product/size: 400LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ETHYL ACETATE
Hazard Class: 3
UN/NA: UN1173
Packing Group: II
Information reported for product/size: 400LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Ethyl Acetate (141-78-6) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Ethyl Acetate (141-78-6) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Ethyl Acetate (141-78-6) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Ethyl Acetate (141-78-6) 5000 U112 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 3[Y]E
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information
required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 3 Reactivity: 0
Label Hazard Warning:
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED OR INHALED. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES
IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Label Precautions:
Keep away from heat, sparks and flame.
Avoid breathing vapor.
Keep container closed.
Use only with adequate ventilation.
Avoid contact with eyes, skin and clothing.
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ETHYL ACETATE 09/06/2005 05:19 PM
Wash thoroughly after handling.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before
reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, give large amounts of water to
drink. Never give anything by mouth to an unconscious person. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy.
This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING
WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT
BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
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