CG2 Page 1 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME: 3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V
SYNONYMS
"alcoholic hand rub"
PROPER SHIPPING NAME
ETHANOL (ETHYL ALCOHOL) ETHANOL SOLUTION (ETHYL ALCOHOL SOLUTION) ETHANOL (ETHYL ALCOHOL) or ETHANOL
SOLUTION (ETHYL ALCOHOL SOLUTION)
PRODUCT USE
Alcoholic hand rub.
SUPPLIER
Company: 3M Australia Pty Ltd Company: 3M Australia Pty Ltd
Address: Address:
PO Box 144 2-74 Dunheved Circuit
St Marys St Marys
NSW, 2761 NSW, 2760
AUS AUS
Telephone: +61 2 9677 5333
Telephone: 136 136
Emergency Tel: +61 2 9 677 5333 (24hr)
Fax: +61 2 9677 5170
HAZARD RATINGS
Min Max
Flammability: 3
Toxicity: 2
Body Contact: 2 Min/Nil=0
Low=1
Reactivity: 0 Moderate=2
High=3
Chronic: 2
Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC, and the ADG Code.
POISONS SCHEDULE
None
RISK SAFETY
Highly flammable. Keep away from sources of ignition. No smoking.
Irritating to eyes. Do not breathe gas/fumes/vapour/spray.
Inhalation and/or ingestion may produce health damage*. Wear eye/face protection.
Cumulative effects may result following exposure*. Use only in well ventilated areas.
May produce discomfort of the respiratory system and Keep container in a well ventilated place.
skin*.
Possible skin sensitiser*. Do not empty into drains.
Vapours potentially cause drowsiness and dizziness*. To clean the floor and all objects contaminated by this
material, use water.
* (limited evidence). Keep container tightly closed.
Take off immediately all contaminated clothing.
In case of contact with eyes, rinse with plenty of water and
contact Doctor or Poisons Information Centre.
If swallowed, IMMEDIATELY contact Doctor or Poisons
Information Centre. (show this container or label).
This material and its container must be disposed of as
hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
ethanol 64-17-5 40-70
glycerol 56-81-5 0.5-1.5
chlorhexidine gluconate 18472-51-0 0.1-1
fragrance 0.1-1
polypropylene glycol 15-stearyl ether 25231-21-4 0.1-1
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CG2 Page 2 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
C.I. Acid Red 33 3567-66-6 0-0.01
water 7732-18-5 40-70
Section 4 - FIRST AID MEASURES
SWALLOWED
For advice, contact a Poisons Information Centre or a doctor at once.
Urgent hospital treatment is likely to be needed.
If swallowed do NOT induce vomiting.
If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent
aspiration.
Observe the patient carefully.
Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious.
Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink.
Transport to hospital or doctor without delay.
EYE
If this product comes in contact with the eyes:
Wash out immediately with fresh running water.
Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the
upper and lower lids.
If pain persists or recurs seek medical attention.
Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.
SKIN
If skin contact occurs:
Immediately remove all contaminated clothing, including footwear
Flush skin and hair with running water (and soap if available).
Seek medical attention in event of irritation.
INHALED
If fumes or combustion products are inhaled remove from contaminated area.
Lay patient down. Keep warm and rested.
Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures.
Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as
trained. Perform CPR if necessary.
Transport to hospital, or doctor.
NOTES TO PHYSICIAN
Treat symptomatically.
Suggested treatment regime for biguanide intoxication:
Establish airway and assist ventilation with positive end expiratory pressure, if required, after endotracheal intubation. Circulatory
competence must be maintained - monitor blood pressure carefully.
Induction of emesis with Ipecac may be contraindicated as a result of biguanide-induced gastric mucosal irritation.
Gastric lavage, following endotracheal intubation may be preferred. Activated charcoal and cathartics placed through the lavage
tube may be useful.
Forcing fluids may be counterproductive and result in fluid overload.
Haemodialysis may be useful as, in addition to facilitating the removal of biguanide and excess lactate, it permits the administration
of adequate amounts of sodium bicarbonate without the risk of fluid overload or hypernatraemia.
Hypoglycaemia can be treated immediately with 50 ml of 50% glucose intravenously in adults or 0.5 g/kg per dose in children.
Acidosis may be treated with IV sodium bicarbonate (1-2 mEq/kg); doses of 44-50 mEq every 15 minutes may be required. Ensure
that arterial blood gases, serum sodium chloride, potassium and ECG are monitored. The patient may require 200-400 mEq of
sodium bicarbonate.
Dehydration and hypovolaemia may require placement of a central venous line.
Hypotension may be treated by placing the patient in Trendelenburg's position and the cautious use of IV fluids. Pressor amines
should be used cautiously, with blood lactate monitoring, as they may increase lactic acid production.
ELLENHORN and BARCELOUX: Medical Toxicology; Diagnosis and Treatment of Human Poisoning. 1988.
For acute or short term repeated exposures to ethanol:
Acute ingestion in non-tolerant patients usually responds to supportive care with special attention to prevention of aspiration,
replacement of fluid and correction of nutritional deficiencies (magnesium, thiamine pyrodoxine, Vitamins C K)
Give 50% dextrose (50-100 ml) IV to obtunded patients following blood draw for glucose determination.
Comatose patients should be treated with initial attention to airway, breathing, circulation and drugs of immediate importance
(glucose, thiamine)
Decontamination is probably unnecessary more than 1 hour after a single observed ingestion. Cathartics and charcoal may be
given but are probably not effective in single ingestions.
Fructose administration is contra-indicated due to side effects.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
The product contains a substantial proportion of water, therefore there are no restrictions on the type of extinguishing media which
may be used. Choice of extinguishing media should take into account surrounding areas.
Though the material is non-combustible, evaporation of water from the mixture, caused by the heat of nearby fire, may produce floating
layers of combustible substances.
In such an event consider:
foam
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Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
dry chemical powder
carbon dioxide
FIRE FIGHTING
Alert Fire Brigade and tell them location and nature of hazard.
May be violently or explosively reactive.
Wear breathing apparatus plus protective gloves.
Prevent, by any means available, spillage from entering drains or water course.
Consider evacuation (or protect in place).
Fight fire from a safe distance, with adequate cover.
If safe, switch off electrical equipment until vapour fire hazard removed.
Use water delivered as a fine spray to control the fire and cool adjacent area.
Avoid spraying water onto liquid pools.
Do not approach containers suspected to be hot.
Cool fire exposed containers with water spray from a protected location.
If safe to do so, remove containers from path of fire.
FIRE/EXPLOSION HAZARD
Liquid and vapour are highly flammable.
Severe fire hazard when exposed to heat, flame and/or oxidisers.
Vapour may travel a considerable distance to source of ignition.
Heating may cause expansion or decomposition leading to violent rupture of containers.
On combustion, may emit toxic fumes of carbon monoxide (CO).
Combustion products include:
carbon dioxide (CO2).
hydrogen chloride.
phosgene.
other pyrolysis products typical of burning organic material.
FIRE INCOMPATIBILITY
None known.
HAZCHEM
2[Y]E
Personal Protective Equipment
Breathing apparatus.
Gas tight chemical resistant suit.
Limit exposure duration to 1 BA set30 mins.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
Remove all ignition sources.
Clean up all spills immediately.
Avoid breathing vapours and contact with skin and eyes.
Control personal contact by using protective equipment.
Contain and absorb small quantities with vermiculite or other absorbent material.
Wipe up.
Collect residues in a flammable waste container.
MAJOR SPILLS
Clear area of personnel and move upwind.
Alert Fire Brigade and tell them location and nature of hazard.
May be violently or explosively reactive.
Wear breathing apparatus plus protective gloves.
Prevent, by any means available, spillage from entering drains or water course.
Consider evacuation (or protect in place).
No smoking, naked lights or ignition sources.
Increase ventilation.
Stop leak if safe to do so.
Water spray or fog may be used to disperse /absorb vapour.
Contain spill with sand, earth or vermiculite.
Use only spark-free shovels and explosion proof equipment.
Collect recoverable product into labelled containers for recycling.
Absorb remaining product with sand, earth or vermiculite.
Collect solid residues and seal in labelled drums for disposal.
Wash area and prevent runoff into drains.
If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
From IERG (Canada/Australia)
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CG2 Page 4 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
Isolation Distance 25 metres
Downwind Protection Distance 300 metres
IERG Number 14
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk of harmful exposure. This zone assumes that random changes in wind direction
confines the vapour plume to an area within 30 degrees on either side of the predominant wind direction, resulting in a crosswind protective action distance equal to the
downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with those closest to the spill and working away from the site in the downwind direction.
Within the protective action zone a level of vapour concentration may exist resulting in nearly all unprotected persons becoming incapacitated and unable to take
protective action and/or incurring serious or irreversible health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the incident, within which a high probability of localised wind reversal may expose nearly all
persons without appropriate protection to life-threatening concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less, such as a drum (jerrican or box with inner containers). Larger packages leaking less
than 200 litres and compressed gas leaking from a small cylinder are also considered "small spills". LARGE SPILLS involve many small leaking packages or a leaking
package of greater than 200 litres, such as a cargo tank, portable tank or a "one-tonne" compressed gas cylinder.
5 Guide 127 is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed for up to one hour
WITHOUT experiencing or developing
life-threatening health effects is:
ethanol 3300 ppm
water 500 mg/m?br>
irreversible or other serious effects or symptoms which could impair an individual's ability to take protective action is:
ethanol 3300 ppm
water 500 mg/m?br>
other than mild, transient adverse effects without perceiving a clearly defined odour is:
ethanol 3000 ppm
water 500 mg/m?br>
The threshold concentration below which most people. will experience no appreciable risk of health effects:
ethanol 1000 ppm
water 500 mg/m?br>
American Industrial Hygiene Association (AIHA)
Ingredients considered according exceed the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Toxic (T) >= 3.0%
R51 >= 2.5% Corrosive (C) >= 5.0%
else >= 10%
where percentage is percentage of ingredient found in the mixture
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X X X X +
X: Must not be stored together
O: May be stored together with specific preventions
+: May be stored together
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
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CG2 Page 5 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
PROCEDURE FOR HANDLING
Avoid all personal contact, including inhalation.
Wear protective clothing when risk of exposure occurs.
Use in a well-ventilated area.
Prevent concentration in hollows and sumps.
DO NOT enter confined spaces until atmosphere has been checked.
Avoid smoking, naked lights, heat or ignition sources.
When handling, DO NOT eat, drink or smoke.
Vapour may ignite on pumping or pouring due to static electricity.
DO NOT use plastic buckets.
Earth and secure metal containers when dispensing or pouring product.
Use spark-free tools when handling.
Avoid contact with incompatible materials.
Keep containers securely sealed.
Avoid physical damage to containers.
Always wash hands with soap and water after handling.
Work clothes should be laundered separately.
Use good occupational work practice.
Observe manufacturer's storing and handling recommendations.
Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions.
DO NOT allow clothing wet with material to stay in contact with skin.
SUITABLE CONTAINER
Packing as supplied by manufacturer. Plastic containers may only be used if approved for flammable liquid. Check that containers are
clearly labelled and free from leaks.
For low viscosity materials (i) : Drums and jerry cans must be of the non-removable head type. (ii) : Where a can is to be used as
an inner package, the can must have a screwed enclosure.
For materials with a viscosity of at least 2680 cSt. (23 deg. C)
For manufactured product having a viscosity of at least 250 cSt. (23 deg. C)
Manufactured product that requires stirring before use and having a viscosity of at least 20 cSt (25 deg. C)
(i) : Removable head packaging;
(ii) : Cans with friction closures and
(iii) : low pressure tubes and cartridges may be used.
Where combination packages are used, and the inner packages are of glass, there must be sufficient inert cushioning material in
contact with inner and outer packages
In addition, where inner packagings are glass and contain liquids of packing group I there must be sufficient inert absorbent to
absorb any spillage, unless the outer packaging is a close fitting moulded plastic box and the substances are not incompatible with
the plastic.
STORAGE INCOMPATIBILITY
Incompatible with aluminium. DO NOT heat above 49 deg. C. in aluminium equipment.
Avoid strong bases.
Avoid strong acids. Avoid contamination / mixing with oxidising agents as ignition may result.
STORAGE REQUIREMENTS
Store in original containers in approved flame-proof area.
No smoking, naked lights, heat or ignition sources.
DO NOT store in pits, depressions, basements or areas where vapours may be trapped.
Keep containers securely sealed.
Store away from incompatible materials in a cool, dry well ventilated area.
Protect containers against physical damage and check regularly for leaks.
Observe manufacturer's storing and handling recommendations.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
TWA TWA STEL STEL Peak Peak TWA
Source Material
ppm mg/m? ppm mg/m? ppm mg/m? F/CC
Australia Exposure
ethanol (Ethyl alcohol) 1,000 1,880
Standards
Australia Exposure
glycerol (Glycerin mist (a)) 10
Standards
Australia Exposure C.I. Acid Red 33 (Inspirable dust (Not
10
Standards specified))
The following materials had no OELs on our record under the following CAS or Chemwatch
(CW) numbers
?3M Avagard 9250 Antiseptic Hand Rub With CHG 0.5% w/v: No data available for CW:4990
-44
?chlorhexidine gluconate: No data available for CAS:18472-51-0
?polypropylene glycol 15-stearyl ether: No data available for CAS:25231-21-4
?C.I. Acid Red 33: No data available for CAS:3567-66-6
?water: No data available for CAS:7732-18-5
EMERGENCY EXPOSURE LIMITS
Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
ethanol 3,300 [LEL]
NOTES
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Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
Values marked LEL indicate that the IDLH was based on 10% of the lower explosive limit
for safety considerations even though the relevant toxicological data indicated that
irreversible health effects or impairment of escape existed only at higher
concentrations.
ODOUR SAFETY FACTOR (OSF)
OSF=6 (ETHANOL)
Exposed individuals are NOT reasonably expected to be warned, by smell, that the Exposure Standard is being exceeded.
Odour Safety Factor (OSF) is determined to fall into either Class C, D or E.
The Odour Safety Factor (OSF) is defined as:
OSF= Exposure Standard (TWA) ppm/ Odour Threshold Value (OTV) ppm
Classification into classes follows:
Class OSF Description
Over 90% of exposed individuals are aware
by smell that the Exposure Standard (TLV-
A 550
TWA for example) is being reached, even
when distracted by working activities
As "A" for 50-90% of persons being
B 26-550
distracted
As "A" for less than 50% of persons being
C 1-26
distracted
10-50% of persons aware of being tested
D 0.18-1 perceive by smell that the Exposure
Standard is being reached
As "D" for less than 10% of persons aware
E <0.18
of being tested
.
EXPOSURE STANDARDS FOR MIXTURE
"Worst Case" computer-aided prediction of vapour components/concentrations:
"Worst Case" computer-aided prediction of vapour components/concentrations:
Composite Exposure Standard for Mixture (TWA) (mg/m?: 7.0737 mg/m?br>
If the breathing zone concentration of ANY of the components listed below is exceeded, "Worst Case" considerations deem the
individual to be overexposed.
Component Breathing Zone ppm Breathing Zone mg/m?Mixture Conc: (%).
Component Breathing zone Breathing Zone Mixture Conc
(ppm) (mg/m? (%)
chlorhexidine gluconate 0.00 0.0996 1.0
ethanol 3.71 6.9740 70.0
Operations which produce a spray/mist or fume/dust, introduce particulates to the breathing zone.
If the breathing zone concentration of ANY of the components listed below is exceeded, "Worst Case" considerations deem the
individual to be overexposed.
At the "Composite Exposure Standard for Mixture" (TWA) (mg/m?: 71 mg/m?br>
Component Breathing Zone Concentration
(mg/m? (%)
glycerol 0.1494 1.5
C.I. Acid Red 33 0.0000 0.0
REPRODUCTIVE HEALTH GUIDELINES
Established occupational exposure limits frequently do not take into consideration reproductive end points that are clearly below the
thresholds for other toxic effects. Occupational reproductive guidelines (ORGs) have been suggested as an additional standard. These
have been established after a literature search for the reproductive no-observed-adverse effect-level (NOAEL) and the lowest-
observed-adverse-effect-level (LOAEL). In addition the US EPA's procedures for risk assessment for hazard identification and dose-
response assessment as applied by NIOSH were used in the creation of such limits. Uncertainty factors (UFs) have also been
incorporated.
Ingredient ORG UF Endpoint CR TLV Adeq
ethanol 1880 mg/m? NA NA NA Yes
These exposure guidelines have been derived from a screening level of risk assessment and should not be construed as
unequivocally safe limits. ORGS represent an 8-hour time-weighted average unless specified otherwise.
CR = Cancer Risk/10000; UF = Uncertainty factor:
TLV believed to be adequate to protect reproductive health:
LOD: Limit of detection
Toxic endpoints have also been identified as:
D = Developmental; R = Reproductive; TC = Transplacental carcinogen
Jankovic J., Drake F.: A Screening Method for Occupational Reproductive
American Industrial Hygiene Association Journal 57: 641-649 (1996).
INGREDIENT DATA
ETHANOL:
Odour Threshold Value: 49-716 ppm (detection), 101 ppm (recognition) Eye and respiratory tract irritation do not appear to occur at
exposure levels of less than 5000 ppm and the TLV-TWA is thought to provide an adequate margin of safety against such effects.
Experiments in man show that inhalation of 1000 ppm caused slight symptoms of poisoning and 5000 ppm caused strong stupor and
morbid sleepiness. Subjects exposed to 5000 ppm to 10000 ppm experienced smarting of the eyes and nose and coughing.
Symptoms disappeared within minutes. Inhalation also causes local irritating effects to the eyes and upper respiratory tract,
headaches, sensation of heat intraocular tension, stupor, fatigue and a need to sleep. At 15000 ppm there was continuous
lachrymation and coughing.
GLYCEROL:
The mist is considered to be a nuisance particulate which appears to have little adverse effect on the lung and does produce
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Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
significant organic disease or toxic effects. OSHA concluded that this limit would protect the worker form kidney damage and perhaps,
testicular effects.
CHLORHEXIDINE GLUCONATE:
CEL TWA: 0.0027 ppm; 0.1 mg/m? *[AstraZeneca]
For each of the following
POLYPROPYLENE GLYCOL 15-STEARYL ETHER:
WATER:
No exposure limits set by NOHSC or ACGIH.
C.I. ACID RED 33:
These "dusts" have little adverse effect on the lungs and do not produce toxic effects or organic disease. Although there is no dust
which does not evoke some cellular response at sufficiently high concentrations, the cellular response caused by P.N.O.C.s has the
following characteristics:
the architecture of the air spaces remain intact,
scar tissue (collagen) is not synthesised to any degree,
tissue reaction is potentially reversible.
Extensive concentrations of P.N.O.C.s may:
seriously reduce visibility,
cause unpleasant deposits in the eyes, ears and nasal passages,
contribute to skin or mucous membrane injury by chemical or mechanical action, per se, or by the rigorous skin cleansing
procedures necessary for their removal. [ACGIH]
This limit does not apply:
to brief exposures to higher concentrations
nor does it apply to those substances that may cause physiological impairment at lower concentrations but for which a TLV has as
yet to be determined.
This exposure standard applies to particles which
are insoluble or poorly soluble* in water or, preferably, in aqueous lung fluid (if data is available) and
have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise chemically reactive with lung tissue, and do not emit ionizing
radiation, cause immune sensitization, or cause toxic effects other than by inflammation or by a mechanism of lung overload)
PERSONAL PROTECTION
EYE
Safety glasses with side shields.
Chemical goggles.
Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document,
describing the wearing of lens or restrictions on use, should be created for each workplace or task. This should include a review of
lens absorption and adsorption for the class of chemicals in use and an account of injury experience. Medical and first-aid
personnel should be trained in their removal and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens should be removed at the first signs of eye
redness or irritation - lens should be removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59]
HANDS/FEET
Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber.
NOTE: The material may produce skin sensitisation in predisposed individuals. Care must be taken, when removing gloves and other
protective equipment, to avoid all possible skin contact.
OTHER
Overalls.
PVC Apron.
PVC protective suit may be required if exposure severe.
Eyewash unit.
Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
"Forsberg Clothing Performance Index".
The effect(s) of the following substance(s) are taken into account in the computer-generated selection: ethanol, water, glycerol
Protective Material CPI *.
NATURAL RUBBER C
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove, a final selection must be based on detailed
observation. -
* Where the glove is to be used on a short term, casual or infrequent basis, factors such as "feel" or convenience (e.g. disposability),
may dictate a choice of gloves which might otherwise be unsuitable following long-term or frequent use. A qualified practitioner should
be consulted.
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Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
The local concentration of material, quantity and conditions of use determine the type of personal protective equipment required.
For further information consult site specific CHEMWATCH data (if available), or your Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
For flammable liquids and flammable gases, local exhaust ventilation or a process enclosure ventilation system may be required.
Ventilation equipment should be explosion-resistant.
Air contaminants generated in the workplace possess varying "escape" velocities which, in turn, determine the "capture velocities" of
fresh circulating air required to effectively remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating from tank (in still
0.25-0.5 m/s (50-100 f/min.)
air).
aerosols, fumes from pouring operations, intermittent container
filling, low speed conveyer transfers, welding, spray drift, plating
0.5-1 m/s (100-200 f/min.)
acid fumes, pickling (released at low velocity into zone of active
generation)
direct spray, spray painting in shallow booths, drum filling,
conveyer loading, crusher dusts, gas discharge (active generation 1-2.5 m/s (200-500 f/min.)
into zone of rapid air motion)
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to capture 1: Disturbing room air currents
2: Contaminants of low toxicity or of nuisance value only. 2: Contaminants of high toxicity
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood-local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. Velocity generally
decreases with the square of distance from the extraction point (in simple cases). Therefore the air speed at the extraction point should
be adjusted, accordingly, after reference to distance from the contaminating source. The air velocity at the extraction fan, for example,
should be a minimum of 1-2 m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from the extraction
point. Other mechanical considerations, producing performance deficits within the extraction apparatus, make it essential that
theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Pale pink highly flammable liquid with a light fragrant odour; mixes with water.
PHYSICAL PROPERTIES
Liquid.
Mixes with water.
Molecular Weight: Not Applicable Boiling Range (癈): 78
Melting Range (癈): Not Available Specific Gravity (water=1): 0.85-0.9
Solubility in water (g/L): Miscible pH (as supplied): 7-9
pH (1% solution): Not Available Vapour Pressure (kPa): Not Available
Volatile Component (%vol): 59 Evaporation Rate: Not Available
Relative Vapour Density (air=1): Not Available Flash Point (癈): 22
Lower Explosive Limit (%): 3.5 Upper Explosive Limit (%): 19
Autoignition Temp (癈): Not Available Decomposition Temp (癈): Not Available
State: Liquid Viscosity: Not Available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
Segregate from.
strong oxidisers.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Considered an unlikely route of entry in commercial/industrial environments.
Ingestion may result in nausea, abdominal irritation, pain and vomiting.
Accidental ingestion of the material may be damaging to the health of the individual.
Ingestion of ethanol (ethyl alcohol, "alcohol") may produce nausea, vomiting, bleeding from the digestive tract, abdominal pain, and
diarrhoea. Effects on the body:
Blood concentration Effects
Mild: impaired vision, co-ordination and reaction time; emotional
<1.5 g/L
instability
Moderate: Slurred speech, confusion, inco-ordination, emotional
instability, disturbances in perception and senses, possible
blackouts, and impaired objective performance in standardized
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CG2 Page 9 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
tests. Possible double vision, flushing, fast heart rate, sweating
and incontinence. Slow breathing may occur rarely and fast
1.5-3.0 g/L breathing may develop in cases of metabolic acidosis, low blood
sugar and low blood potassium. Central nervous system
depression may progress to coma.
Severe: cold clammy skin, low body temperature and low blood
pressure. Atrial fibrillation and heart block have been reported.
Depression of breathing may occur, respiratory failure may follow
3-5 g/L
serious poisoning, choking on vomit may result in lung
inflammation and swelling. Convulsions due to severe low blood
sugar may also occur. Acute liver inflammation may develop.
.
EYE
There is evidence that material may produce eye irritation in some persons and produce eye damage 24 hours or more after
instillation. Severe inflammation may be expected with pain. There may be damage to the cornea. Unless treatment is prompt and
adequate there may be permanent loss of vision. Conjunctivitis can occur following repeated exposure.
Direct contact of the eye with ethanol may cause immediate stinging and burning with reflex closure of the lid and tearing, transient
injury of the corneal epithelium and hyperaemia of the conjunctiva. Foreign-body type discomfort may persist for up to 2 days but
healing is usually spontaneous and complete.
The material may produce severe irritation to the eye causing pronounced inflammation. Repeated or prolonged exposure to irritants
may produce conjunctivitis.
SKIN
There is some evidence to suggest that the material may cause moderate inflammation of the skin either following direct contact or
after a delay of some time. Repeated exposure can cause contact dermatitis which is characterised by redness, swelling and
blistering.
The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the
production of vesicles, scaling and thickening of the skin.
INHALED
Inhalation of vapours or aerosols (mists, fumes), generated by the material during the course of normal handling, may be damaging to
the health of the individual.
There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such
irritation can cause further lung damage.
Inhalation of vapours may cause drowsiness and dizziness. This may be accompanied by sleepiness, reduced alertness, loss of
reflexes, lack of co-ordination, and vertigo.
The most common signs of inhalation overexposure to ethanol, in animals, include ataxia, incoordination and drowsiness for those
surviving narcosis. The narcotic dose for rats, after 2 hours of exposure, is 19260 ppm.
Inhalation of high concentrations of gas/vapour causes lung irritation with coughing and nausea, central nervous depression with
headache and dizziness, slowing of reflexes, fatigue and inco-ordination.
CHRONIC HEALTH EFFECTS
Substance accumulation, in the human body, may occur and may cause some concern following repeated or long-term occupational
exposure.
There is limited evidence that, skin contact with this product is more likely to cause a sensitisation reaction in some persons compared
to the general population.
Sensitisation may result in allergic dermatitis responses including rash, itching, hives or swelling of extremities.
TOXICITY AND IRRITATION
Not available. Refer to individual constituents.
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances
TOXICITY IRRITATION
ETHANOL:
Oral (rat) LD50: 7060 mg/kg Skin (rabbit):20 mg/24hr- Moderate
Oral (human) LDLo: 1400 mg/kg Skin (rabbit):400 mg (open)- Mild
Oral (man) TDLo: 50 mg/kg Eye (rabbit):100mg/24hr- Moderate
Oral (man) TDLo: 1.40 mg/kg Eye (rabbit): 500 mg SEVERE
Oral (woman) TDLo: 256 mg/kg/12 wks
Inhalation (rat) LC50: 20, 000 ppm/10h
Inhalation (rat) LC50: 64000 ppm/4h
GLYCEROL:
Oral (Rat) LD50: 12600 mg/kg
The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or prolonged exposure to irritants
may produce conjunctivitis.
The material may cause skin irritation after prolonged or repeated exposure and may produce a contact dermatitis (nonallergic). This
form of dermatitis is often characterised by skin redness (erythema) and swelling epidermis. Histologically there may be intercellular
oedema of the spongy layer (spongiosis) and intracellular oedema of the epidermis.
CHLORHEXIDINE GLUCONATE:
Oral (rat) LD50: 2000 mg/kg Nil Reported
Subcutaneous (rat) LD50: 3320 mg/kg
Intravenous (rat) LD50: 24.2 mg/kg
POLYPROPYLENE GLYCOL 15-STEARYL ETHER:
Oral (rat) LD50: >5000 mg/kg Skin: Minimally Irritant
Eyes: Minimally Irritant [ICI]
C.I. ACID RED 33:
Not available.
Bacterial cell mutagen
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CG2 Page 10 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
WARNING: Limited animal studies have indicated that some azo dyes may be
potential carcinogens and therefore extensive care should be exercised in
their handling.
WATER:
No significant acute toxicological data identified in literature search.
MATERIAL CARCINOGEN REPROTOXIN SENSITISER SKIN
ethanol ILOM
REPROTOXIN
ILOM: ILO Agents toxic to the male reproductive system: ethanol
Section 12 - ECOLOGICAL INFORMATION
DO NOT discharge into sewer or waterways.
Refer to data for ingredients, which follows:
ETHANOL:
Fish LC50 (96hr.) (mg/l): 13480
Algae IC50 (72hr.) (mg/l): 1450
log Kow (Sangster 1997): - 0.3
BOD5: 63%
ThOD: 2.1
Half- life Soil - High (hours): 24
Half- life Soil - Low (hours): 2.6
Half- life Air - High (hours): 122
Half- life Air - Low (hours): 12.2
Half- life Surface water - High (hours): 26
Half- life Surface water - Low (hours): 6.5
Half- life Ground water - High (hours): 52
Half- life Ground water - Low (hours): 13
Aqueous biodegradation - Aerobic - High (hours): 26
Aqueous biodegradation - Aerobic - Low (hours): 6.5
Aqueous biodegradation - Anaerobic - High (hours): 104
Aqueous biodegradation - Anaerobic - Low (hours): 26
Aqueous biodegradation - Removal secondary treatment - High (hours): 67%
Photooxidation half- life water - High (hours): 3.20E+05
Photooxidation half- life water - Low (hours): 8020
Photooxidation half- life air - High (hours): 122
Photooxidation half- life air - Low (hours): 12.2
DO NOT discharge into sewer or waterways.
log Kow: -0.31- -0.32
Half-life (hr) air: 144
Half-life (hr) H2O surface water: 144
Henry's atm m?/mol: 6.29E-06
BOD 5 if unstated: 0.93-1.67,63%
COD: 1.99-2.11,97%
ThOD: 2.1
When ethanol is released into the soil it readily and quickly biodegrades
but may leach into ground water; most is lost by evaporation. When
released into water the material readily evaporates and is biodegradable.
Ethanol does not bioaccumulate to an appreciable extent.
The material is readily degraded by reaction with photochemically produced
hydroxy radicals; release into air will result in photodegradation and wet
deposition.
GLYCEROL:
Algae IC50 (72hr.) (mg/l): 2900- 10000
log Kow (Sangster 1997): - 1.76
log Pow (Verschueren 1983): 1.07692307
BOD5: 51%
COD: 95%
ThOD: 93%
DO NOT discharge into sewer or waterways.
log Kow: -2.66- -2.47
BOD 5 if unstated: 0.617-0.87,31-51%
COD: 1.16,82-95%
ThOD: 1.217-1.56
Completely biodegradable.
Fish LC50: >5000 mg/l
Algae IC50: >2900 mg/l
Bacteria EC50: .10000 mg/l (Pseudomonas putida)
CHLORHEXIDINE GLUCONATE:
Do NOT allow product to come in contact with surface waters or to intertidal areas below the mean high water mark. Do not
contaminate water when cleaning equipment or disposing of equipment wash-waters.
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CG2 Page 11 of 11
Hazard Alert Code:
3M AVAGARD 9250 ANTISEPTIC HAND RUB WITH CHG 0.5% W/V HIGH
Chemwatch Material Safety Data Sheet (REVIEW) Revision No: 2 Chemwatch 4990-44
Issue Date: 23-Jul-2004 CD 2006/3
Wastes resulting from use of the product must be disposed of on site or at approved waste sites.
DO NOT discharge into sewer or waterways.
Section 13 - DISPOSAL CONSIDERATIONS
Containers may still present a chemical hazard/ danger when empty.
Return to supplier for reuse/ recycling if possible.
Otherwise:
If container can not be cleaned sufficiently well to ensure that residuals do not remain or if the container cannot be used to store
the same product, then puncture containers, to prevent re-use, and bury at an authorised landfill
Where possible retain label warnings and MSDS and observe all notices pertaining to the product.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: FLAMMABLE LIQUID
HAZCHEM: 2[Y]E
UNDG:
Dangerous Goods Class: 3 Subrisk: None
UN Number: 1170 Packing Group: II
Shipping Name:ETHANOL (ETHYL ALCOHOL)
ETHANOL SOLUTION (ETHYL ALCOHOL SOLUTION)
ETHANOL (ETHYL ALCOHOL) or ETHANOL SOLUTION (ETHYL ALCOHOL SOLUTION)
Air Transport IATA:
ICAO/IATA Class: 3 ICAO/IATA Subrisk: None
UN/ID Number: 1170 Packing Group: II
ERG Code: 3L
Shipping Name: Ethanol
Maritime Transport IMDG:
IMDG Class: 3 IMDG Subrisk: None
UN Number: 1170 Packing Group: II
EMS Number: F-E,S-D
Shipping Name: ETHANOL SOLUTION (ETHYL ALCOHOL SOLUTION)
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE
None
REGULATIONS
ethanol (CAS No:64- 17- 5):
No regulations applicable
No data available for ethanol as CAS: 64- 17- 5.
No data available for glycerol as CAS: 56- 81- 5.
No data available for chlorhexidine gluconate as CAS: 18472- 51- 0.
No data available for polypropylene glycol 15- stearyl ether as CAS: 25231- 21-
4.
No data available for C.I. Acid Red 33 as CAS: 3567- 66- 6.
No data available for water as CAS: 7732- 18- 5.
Section 16 - OTHER INFORMATION
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or criticism, as permitted
under the Copyright Act, no part may be reproduced by any process without written permission from CHEMWATCH. TEL (+61 3) 9572
4700.
Issue Date: 23-Jul-2004
Print Date: 24-Aug-2006
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