Part of Thermo Fisher Scientific
Pentafluoropropionic Acid Anhydride
2. Hazards identification
Material Safety Data Sheet May cause target organ damage, based on animal data.
Chronic effects :
No known significant effects or critical hazards.
Carcinogenicity :
1. Product and company identification No known significant effects or critical hazards.
Mutagenicity :
No known significant effects or critical hazards.
Teratogenicity :
Pentafluoropropionic Acid Anhydride
Product name :
No known significant effects or critical hazards.
Developmental effects :
Pentafluoropropionic Acid Anhydride
Synonym :
No known significant effects or critical hazards.
Fertility effects :
(C3F5O)2O
Chemical formula :
May cause damage to the following organs: mucous membranes, upper respiratory tract,
Target organs :
Thermo Fisher Scientific : Thermo Fisher Scientific
Supplier : Manufacturer
skin, eyes.
Pierce Biotechnology Pierce Biotechnology
P.O. Box 117 P.O. Box 117 Over-exposure signs/symptoms
Rockford, IL 61105 Rockford, IL 61105
: Adverse symptoms may include the following:
Inhalation
United States United States
respiratory tract irritation
815.968.0747 or 815.968.0747
coughing
800.874.3723 800.874.3723
: Adverse symptoms may include the following:
Ingestion
0065191 0065192 0065193
Product No. : stomach pains
554
MSDS # : : Adverse symptoms may include the following:
Skin
Validation date : 10/2/2008. pain or irritation
redness
10/2/2008.
Print date :
blistering may occur
Responsible name : MSDS Specialist
: Adverse symptoms may include the following:
Eyes
CHEMTREC: Use of : Refer to the instruction booklet for
In case of emergency :
pain
800.424.9300 Substance/Preparation proper and intended use.
watering
OUTSIDE US: Otherwise, contact supplier for
redness
202.483.7616 specific applications.
: Pre-existing disorders involving any target organs mentioned in this MSDS as being at
Medical conditions
risk may be aggravated by over-exposure to this product.
aggravated by over-
exposure
2. Hazards identification
: Liquid.
Physical state The substance is not classified as dangerous according to Directive 67/548/EEC and its amendments.
: Stench.
Odor : Not classified.
Classification
: This material is considered hazardous by the OSHA Hazard Communication Standard
OSHA/HCS status See toxicological information (section 11)
(29 CFR 1910.1200).
3. Composition/information on ingredients
: DANGER !
Emergency overview
WATER-REACTIVE SUBSTANCE. REACTS WITH WATER TO RELEASE TOXIC United States
GAS. MAY BE FATAL IF INHALED. CAUSES RESPIRATORY TRACT, EYE AND
Name CAS number %
SKIN BURNS. MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA.
Pentafluoropropionic Acid Anhydride 356-42-3 98 - 100
Contact with water liberates toxic gas. Corrosive to the eyes, skin and respiratory
system. Causes burns. Keep away from water. Do not breathe gas. Do not breathe
: Substance
Substance/preparation
vapor or mist. Do not get in eyes or on skin or clothing. May cause target organ
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
damage, based on animal data. Use only with adequate ventilation. Keep container
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
tightly closed and sealed until ready for use. Wash thoroughly after handling.
reporting in this section.
: Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of entry
Potential acute health effects
: Corrosive to the respiratory system.
Inhalation
: May cause burns to mouth, throat and stomach.
Ingestion
: Corrosive to the skin. Causes burns.
Skin
: Corrosive to eyes. Causes burns.
Eyes
Potential chronic health effects
1/8 2/8
10/2/2008. 10/2/2008.
Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce
Pierce PO Box 117 61105 (815) 968-7316 Fax Pierce PO Box 117 61105 (815) 968-7316 Fax
Pentafluoropropionic Acid Anhydride Pentafluoropropionic Acid Anhydride
4. First aid measures 6. Accidental release measures
: No action shall be taken involving any personal risk or without suitable training.
: Get medical attention immediately. Move exposed person to fresh air. If it is suspected Personal precautions
Inhalation
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
that fumes are still present, the rescuer should wear an appropriate mask or self-
entering. Do not touch or walk through spilled material. Keep away from water. Avoid
contained breathing apparatus. Keep person warm and at rest. If not breathing, if
breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator
breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen
when ventilation is inadequate. Put on appropriate personal protective equipment (see
by trained personnel. It may be dangerous to the person providing aid to give mouth-to-
section 8).
mouth resuscitation. If unconscious, place in recovery position and get medical attention
immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
Environmental precautions
waistband. and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
: Get medical attention immediately. Wash out mouth with water. Remove dentures if
Ingestion
any. Move exposed person to fresh air. Keep person warm and at rest. If material has : Stop leak if without risk. Move containers from spill area. Approach release from
Large spill
been swallowed and the exposed person is conscious, give small quantities of water to upwind. Prevent entry into sewers, water courses, basements or confined areas. Avoid
drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not allowing the spilled material to get wet or using water to clean up spillages or residues,
induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the unless the quantity remaining is very small. Contain and collect spillage with non-
head should be kept low so that vomit does not enter the lungs. Chemical burns must combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and
be treated promptly by a physician. Never give anything by mouth to an unconscious place in container for disposal according to local regulations (see section 13). Dispose
person. If unconscious, place in recovery position and get medical attention of via a licensed waste disposal contractor. Contaminated absorbent material may pose
immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or the same hazard as the spilled product. Note: see section 1 for emergency contact
waistband. information and section 13 for waste disposal.
: Get medical attention immediately. Flush contaminated skin with plenty of water.
Skin contact : Stop leak if without risk. Move containers from spill area. Avoid allowing the spilled
Small spill
Remove contaminated clothing and shoes. Wash contaminated clothing thoroughly with material to get wet or using water to clean up spillages or residues, unless the quantity
water before removing or wear gloves. Continue to rinse for at least 10 minutes. remaining is very small. Absorb with an inert material and place in an appropriate waste
Chemical burns must be treated promptly by a physician. Wash clothing before reuse. disposal container. Dispose of via a licensed waste disposal contractor.
Clean shoes thoroughly before reuse.
7. Handling and storage
: Get medical attention immediately. Immediately flush eyes with plenty of water for at
Eye contact
least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove
: Put on appropriate personal protective equipment (see section 8). Eating, drinking and
Handling
any contact lenses. Chemical burns must be treated promptly by a physician.
smoking should be prohibited in areas where this material is handled, stored and
: No action shall be taken involving any personal risk or without suitable training. If it is
Protection of first-aiders processed. Workers should wash hands and face before eating, drinking and smoking.
suspected that fumes are still present, the rescuer should wear an appropriate mask or Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest.
self-contained breathing apparatus. It may be dangerous to the person providing aid to Use only with adequate ventilation. Wear appropriate respirator when ventilation is
give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water inadequate. Keep in the original container or an approved alternative made from a
before removing or wear gloves. compatible material, kept tightly closed when not in use. Keep away from water. Empty
containers retain product residue and can be hazardous. Do not reuse container.
See section 11 for more detailed information on health effects and symptoms.
: Store in accordance with local regulations. Store in original container protected from
Storage
5. Fire-fighting measures direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep away from water. Keep container tightly
: Contact with water liberates toxic gas. In a fire or if heated, a pressure increase will
Flammability of the product
closed and sealed until ready for use. Containers that have been opened must be
occur and the container may burst.
carefully resealed and kept upright to prevent leakage. Do not store in unlabeled
Extinguishing media containers. Use appropriate containment to avoid environmental contamination.
: Use dry chemical or CO2.
Suitable
8. Exposure controls/personal protection
: Do not use water or foam.
Not suitable
: Promptly isolate the scene by removing all persons from the vicinity of the incident if
Special exposure hazards Europe
there is a fire. No action shall be taken involving any personal risk or without suitable
No exposure limit value known.
training.
Consult local authorities for acceptable exposure limits.
: Decomposition products may include the following materials:
Hazardous combustion
carbon oxides : If this product contains ingredients with exposure limits, personal, workplace atmosphere
products Recommended monitoring
halogenated compounds or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
: Fire-fighters should wear appropriate protective equipment and self-contained breathing
Special protective
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
equipment for fire-fighters
3/8 4/8
10/2/2008. 10/2/2008.
Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce
Pierce PO Box 117 61105 (815) 968-7316 Fax Pierce PO Box 117 61105 (815) 968-7316 Fax
Pentafluoropropionic Acid Anhydride Pentafluoropropionic Acid Anhydride
8. Exposure controls/personal protection 10 . Stability and reactivity
: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor : Will not occur.
Engineering measures Possibility of hazardous
or mist, use process enclosures, local exhaust ventilation or other engineering controls reactions
to keep worker exposure to airborne contaminants below any recommended or statutory
11 . Toxicological information
limits. Engineering controls may be required to control the primary or secondary risks
associated with this product.
United States
: Wash hands, forearms and face thoroughly after handling chemical products, before
Hygiene measures Acute toxicity
eating, smoking and using the lavatory and at the end of the working period. Appropriate
: To the best of our knowledge, the toxicological properties of this substance have not
Conclusion/Summary
techniques should be used to remove potentially contaminated clothing. Wash
been thoroughly investigated.
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location. Chronic toxicity
: Not available.
Conclusion/Summary
Personal protection
Carcinogenicity
: Use a properly fitted, air-purifying or air-fed respirator complying with an approved
Respiratory
: Not available.
standard if a risk assessment indicates this is necessary. Respirator selection must be Conclusion/Summary
based on known or anticipated exposure levels, the hazards of the product and the safe Mutagenicity
working limits of the selected respirator.
: Not available.
Conclusion/Summary
: Chemical-resistant, impervious gloves complying with an approved standard should be
Hands
Teratogenicity
worn at all times when handling chemical products if a risk assessment indicates this is
: Not available.
Conclusion/Summary
necessary.
Reproductive toxicity
: Safety eyewear complying with an approved standard should be used when a risk
Eyes
assessment indicates this is necessary to avoid exposure to liquid splashes, mists, : Not available.
Conclusion/Summary
gases or dusts.
Europe
: Personal protective equipment for the body should be selected based on the task being
Skin
performed and the risks involved and should be approved by a specialist before handling No known significant effects or critical hazards.
Chronic effects :
this product.
No known significant effects or critical hazards.
Carcinogenicity :
: Emissions from ventilation or work process equipment should be checked to ensure they
Environmental exposure
No known significant effects or critical hazards.
Mutagenicity :
comply with the requirements of environmental protection legislation. In some cases,
controls
No known significant effects or critical hazards.
Teratogenicity :
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels. No known significant effects or critical hazards.
Developmental effects :
No known significant effects or critical hazards.
Fertility effects :
9. Physical and chemical properties
12 . Ecological information
Liquid.
Physical state :
Clear. Colorless to slightly yellow.
Color : : No known significant effects or critical hazards.
Environmental effects
Stench.
Odor : United States
310.05 g/mole
Molecular weight : Aquatic ecotoxicity
(C3F5O)2O
Molecular formula : : Not available.
Conclusion/Summary
69 to 72癈 (156.2 to 161.6癋)
Boiling/condensation point : : No known significant effects or critical hazards.
Other adverse effects
1.571
Relative density :
13 . Disposal considerations
10 . Stability and reactivity : The generation of waste should be avoided or minimized wherever possible. Dispose of
Waste disposal
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
: The product is stable. Under normal conditions of storage and use, hazardous
Chemical stability
of this product, solutions and any by-products should at all times comply with the
polymerization will not occur.
requirements of environmental protection and waste disposal legislation and any regional
: No specific data.
Conditions to avoid local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
: Reactive or incompatible with the following materials: water
Incompatible materials
: Contact with water liberates toxic gas.
Hazardous decomposition : Within the present knowledge of the supplier, this product is not regarded as
Hazardous waste
hazardous waste, as defined by EU Directive 91/689/EEC.
products
Disposal should be in accordance with applicable regional, national and local laws and regulations.
5/8 6/8
10/2/2008. 10/2/2008.
Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce
Pierce PO Box 117 61105 (815) 968-7316 Fax Pierce PO Box 117 61105 (815) 968-7316 Fax
Pentafluoropropionic Acid Anhydride Pentafluoropropionic Acid Anhydride
13 . Disposal considerations 15 . Regulatory information
: S26- In case of contact with eyes, rinse immediately with plenty of water and seek
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION Safety phrases
medical advice.
for additional handling information and protection of employees.
S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
14 . Transport information S45- In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
Regulatory UN number Proper shipping Classes PG*
information name International regulations
: Australia inventory (AICS): Not determined.
International lists
UN3265 Corrosive liquid, 8 II
DOT Classification
China inventory (IECSC): Not determined.
acidic, organic, n.o.s.
Korea inventory (KECI): Not determined.
UN3265 Corrosive liquid, 8 II
IATA-DGR Class Philippines inventory (PICCS): Not determined.
acidic, organic, n.o.s. Japan inventory (ENCS): Not determined.
PG* : Packing group
16 . Other information
15 . Regulatory information : WATER-REACTIVE SUBSTANCE. REACTS WITH WATER TO RELEASE TOXIC
Label requirements
GAS. MAY BE FATAL IF INHALED. CAUSES RESPIRATORY TRACT, EYE AND
United States
SKIN BURNS. MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA.
: Water-reactive material
HCS Classification
Hazardous Material :
Corrosive material
Target organ effects Information System (U.S.A.)
3
: United States inventory (TSCA 8b): This material is listed or exempted. Health
U.S. Federal regulations
0
SARA 302/304/311/312 extremely hazardous substances: No products were found. Flammability
SARA 302/304 emergency planning and notification: No products were found. 2
Physical hazards
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
The customer is responsible for determining the PPE code for this material.
Clean Water Act (CWA) 307: No products were found.
National Fire Protection :
Clean Water Act (CWA) 311: No products were found.
Association (U.S.A.)
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Flammability
0
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
3 2
Health Instability
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
Canada Special
: Class D-1B: Material causing immediate and serious toxic effects (Toxic).
WHMIS (Canada)
Date of printing : 10/2/2008.
Class E: Corrosive material
Class F: Dangerously reactive material. : 10/2/2008.
Date of issue
: CEPA Toxic substances: This material is not listed. Date of previous issue : 9/30/2008.
Canadian lists
Canadian ARET: This material is not listed. Version : 1.02
Canadian NPRI: This material is not listed.
Indicates information that has changed from previously issued version.
Alberta Designated Substances: This material is not listed.
Notice to reader
Ontario Designated Substances: This material is not listed.
Quebec Designated Substances: This material is not listed. To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
: Canada inventory: This material is not listed in DSL but is listed in NDSL.
Canada inventory
information contained herein.
EU regulations Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
: This product is not classified according to EU legislation.
Risk phrases
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
7/8 8/8
10/2/2008. 10/2/2008.
Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce
Pierce PO Box 117 61105 (815) 968-7316 Fax Pierce PO Box 117 61105 (815) 968-7316 Fax
|