Page 1 of 7
MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Lithium tri-tert-butoxyaluminum hydride in THF
PRODUCT NAME:
alkali metal hydride
CHEMICAL FAMILY:
Li AlH(OC4H9)3
MOLECULAR FORMULA:
Industrial Manufacturing
GENERAL USE:
MANUFACTURER Emergency Telephone Numbers:
FMC CORPORATION CHEMTREC (800) 424-9300
Lithium Division Emergency Phone (704) 629-5361 (Plant) Call
P.O. Box 795 Collect 24 Hr/Day
Bessemer City, NC 28016-0795 Emergency Phone (303) 595-9048 (Medical)
General Information: (704) 868-5300 Call Collect
2. HAZARDS IDENTIFICATION
Substances and mixtures, which on contact with water, emit flammable
CLASSIFICATION:
gases; Category 1
Flammable liquid; Category 2
Corrosive to skin; Category 1
Specific target organ systemic toxicity ?Single exposure; Category 3
LABELING:
Flame, corrosion, exclamation mark
SYMBOLS:
Danger
SIGNAL WORD:
In contact with water releases flammable gases, which may ignite
HAZARD STATEMENTS:
spontaneously
Highly flammable liquid and vapour
Causes severe skin burns and eye damage
May cause respiratory irritation
PRECAUTIONARY STATEMENTS: Prevention:
Keep from any possible contact with water, because of violent reaction
and possible flash fire.
Handle under inert gas, protect from moisture.
Wear chemical splash goggles with a face shield, rubber gloves and
rubber clothing.
Keep away from heat/sparks/open flame -- No smoking.
Keep container tightly closed.
Ground/Bond container and receiving equipment.
Use explosion-proof electrical, ventilation and lighting equipment.
Use only non-sparking tools.
Take precautionary measures against static discharge.
Do not breathe dust or mist.
Wash thoroughly after handling.
Avoid breathing vapours.
Use only outdoors or in well-ventilated area.
Response
In case of fire, use dry chemical for extinction. DO NOT USE WATER
OR CARBON DIOXIDE.
First Aid
See Section 4 of the MSDS.
Storage
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MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
See Section 7 of the MSDS.
Disposal
See Section 13 of the MSDS.
3. COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Name CAS # EC No Wt. Classification, Hazard Statement Codes
%
lithium tri-tert- 17476- 241-490-8 23- Water-react. Cat. 1 H260
butoxyaluminum 04-9 32 Skin Corr. Cat 1A H314
hydride
tetrahydrofuran 109-99- 203-726-8 58- Flam. liq. Cat. 2 H225
9 77 Eye Irrit. Cat. 2 H319
STOT SE Cat. 3 H335
lithium di-tert- 24315- none 0-5 Water-react. Cat. 1 H260
butoxyaluminum 46-6 Skin Corr. Cat 1A H314
hydride
lithium tetra-tert- 69537- none 0-5 Water-react. Cat. 1 H260
butoxyaluminum 16-2 Skin Corr. Cat 1A H314
tert-Butyl alcohol 75-65-0 200-889-7 0-2 Flam. liq. Cat. 2 H225
Acute Tox. Cat. 4 H332
4. FIRST AID MEASURES
Immediately flush with water for at least 15 minutes, lifting the
EYES:
upper and lower eyelids intermittently. See a medical doctor or
ophthalmologist immediately.
Quickly wipe off as much as possible, then immediately flush with
SKIN:
plenty of water while removing contaminated clothing and/or
shoes. Thoroughly wash with soap and water. Obtain immediate
medical attention. Contact a medical doctor if necessary.
Quickly wipe material from the mouth and rinse mouth with water.
INGESTION:
Do not induce vomiting. Never give anything by mouth to an
unconscious person. See a medical doctor immediately.
Remove to fresh air. If breathing discomfort occurs and persists,
INHALATION:
see a medical doctor. If breathing has stopped, give artificial
respiration and see a medical doctor immediately.
NOTES TO MEDICAL DOCTOR:
This product is corrosive to eyes, skin, and mucous membranes. Consideration should be given to careful
endoscopy as stomach or esophageal burns, perforations or strictures may occur. Careful gastric lavage with an
endotracheal tube in place should be considered. Observation may be warranted. Treatment is controlled removal of
exposure followed by symptomatic and supportive care.
5. FIRE FIGHTING MEASURES
Upper: Not available Lower: Not available.
FLAMMABLE LIMITS:
Flammable liquid. Reacts violently with water to give off flammable
GENERAL HAZARD:
fumes and corrosive dust.
DO NOT USE WATER OR CARBON DIOXIDE. Use dry chemical.
EXTINGUISHING MEDIA:
Lithium hydroxide, carbon dioxide, carbon monoxide.
HAZARDOUS COMBUSTION PRODUCTS:
Wear full protective clothing and self-contained breathing apparatus
FIRE FIGHTING PROCEDURES:
(SCBA) approved for fire fighting. This is necessary to protect against
the hazards of heat, products of combustion and oxygen deficiency.
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MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
Do not breathe smoke, gases or vapors generated.
Not applicable
AUTOIGNITION TEMPERATURE:
Water reactivity and volatility of solvents.
PROPERTIES CONTRIBUTING TO
FLAMMABILITY:
-17 C (tetrahydrofuran)
FLASH POINT:
Yes
SENSITIVITY TO STATIC DISCHARGE:
None
SENSITIVITY TO IMPACT:
COMMENTS:
(See Section 10, Stability and Reactivity)
6. ACCIDENTAL RELEASE MEASURES
Remove all sources of ignition. Do not use water in the initial phases
RELEASE NOTES:
of clean up. Hydrogen gas is produced on contact with moisture or
humidity. Take precautions to prevent explosion of hydrogen gas.
Contain spill with absorbent. Transfer to approved transport container
and clean up spillage with an absorbent. Dispose of waste according
to local and Federal laws and regulations.
Before cleanup measures begin, review the entire MSDS with
particular attention to Section 3, Emergency Overview and Potential
Health Effects; and Section 8, Recommended Personal Protective
Equipment.
7. HANDLING AND STORAGE
Use in a closed system under argon or nitrogen. Do not get in eyes,
HANDLING:
on skin or clothing. Do not breathe vapors or mist.
Store in a cool place. Keep container closed. Keep away from
STORAGE:
sources of ignition, water, air, acids and oxidizing agents.
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MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE LIMITS
Chemical Name TWA STEL/Ceiling PEL STEL/Ceiling
(ACGIH) (ACGIH) (OSHA) (OSHA)
tetrahydrofuran 200 ppm 250 ppm 200 ppm
tert-Butyl alcohol 100 ppm 100 ppm
ENGINEERING CONTROLS:
Use in closed system under argon or nitrogen. If personal contact can occur, use local exhaust ventilation
(explosion-proof), to keep airborne concentrations below exposure limits.
PERSONAL PROTECTIVE EQUIPMENT
Chemical splash goggles with a face shield.
Eyes And Face:
When engineering controls are not adequate, wear a NIOSH/MSHA
Respiratory:
respirator approved for protection against organic vapors and mists.
Rubber gloves and rubber clothing.
Protective Clothing:
Quick-drench eyewash and safety shower.
Work Hygienic Practices:
9. PHYSICAL AND CHEMICAL PROPERTIES
That of tetrahydrofuran
ODOR:
Clear to slightly turbid solution, colorless to grey.
APPEARANCE:
Not applicable
pH:
58-77%
PERCENT VOLATILE:
Not available
VAPOR PRESSURE:
(Air = 1): 2
VAPOR DENSITY:
65-67篊 (THF)
BOILING POINT:
Not applicable
MELTING POINT:
Exothermic reaction to form basic lithium hydroxide and hydrogen
SOLUBILITY IN WATER:
gas
Not available
EVAPORATION RATE(Butyl Acetate = 1):
0.904 g/cc (28 wt% in THF)
SPECIFIC GRAVITY:
254.26
MOLECULAR WEIGHT:
Not applicable
COEFF. OIL/WATER:
Not applicable
ODOR THRESHOLD:
Upper: Not available Lower: Not available.
FLAMMABLE LIMITS:
-17 C (tetrahydrofuran)
FLASH POINT:
Not available.
AUTOIGNITION TEMPERATURE:
Not available
VISCOSITY:
Water reactive material in flammable liquid solvent
FLAMMABILITY:
Not available
DECOMPOSITION TEMPERATURE:
Not applicable.
EXPLOSIVE PROPERTIES:
Not applicable.
OXIDIZING PROPERTIES:
10. STABILITY AND REACTIVITY
Contact with water, air
CONDITIONS TO AVOID:
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MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
Stable at room temperature.
STABILITY:
Does not polymerize
POLYMERIZATION:
Lithium hydroxide, aluminum oxides, hydrogen gas. Contact with
HAZARDOUS DECOMPOSITION
moisture or humidity can cause the release of flammable hydrogen
PRODUCTS:
gas and lead to pressure build-up in container.
Acids, alcohols, oxidizers, oxygen, heat, sparks, water and open
INCOMPATIBLE MATERIALS:
flame.
11. TOXICOLOGICAL INFORMATION
No data available for the product.
Eye Contact:
Lithium tri-tert-butoxyaluminum hydride: Corrosive
No data available for the product.
Skin Contact:
Lithium tri-tert-butoxyaluminum hydride: Corrosive
No data available for the product.
Skin Absorption:
t-butanol: LD50: >2 mg/kg (rabbit) [RTECS]
No data available for the product.
Ingestion:
THF: LD50 = 1650 mg/kg (rat) [RTECS]
t-butanol: LD50: = 2743 mg/kg (rat) [RTECS]
No data available for the product.
Inhalation:
THF: LC50 = 21,000 ppm , 3 hr., (rat) [RTECS]
t-butanol: LC50: >10000 ppm (4 hr. rat) [RTECS]
Acute Effects From Overexposure:
No data available for the product. This product is corrosive to skin, eyes (may cause blindness), mucous membranes
and upper respiratory tract. Inhalation of vapors may cause dizziness, nausea, anesthesia, numbness, motor
weakness in fingers and toes, incoordination, and headache.
Chronic Effects From Overexposure:
No data available for the product.
Tetrahydrofuran: Repeated or prolonged exposure may cause signs of central nervous system depression and
respiratory irritation. THF gave negative results in bacterial mutagenicity tests with and without metabolic activation.
One animal study suggests that THF does not cause reproductive effects at doses which are not maternally toxic.
THF is listed by NPT as a substance reasonably anticipated to be a carcinogen. ACGIH lists THF as Category 3, a
confirmed animal carcinogen with unknown relevance to humans.
t-Butanol: Some evidence of carcinogenicity has been observed in male rats and female mice following the
administration of high oral doses for 2 years. The carcinogenic effects were observed in the presence of severe
toxicity in the animals and are of questionable relevance to humans.
No data available for the product.
Sensitization:
EH40: Not listed.
Carcinogenicity:
IARC: Not listed.
NTP: Tetrahydrofuran is listed as a substance that is reasonably
anticipated to be a carcinogen.
OSHA: Not considered a carcinogen under OSHA
OTHER: ACGIH: Tetrahydrofuran is listed as Category A3, a
confirmed animal carcinogen with unknown relevance to humans. t-
Butanol is listed as Category A4, not classifiable as a human
carcinogen.
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MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
No data available for the product.
Mutagenicity:
THF: THF gave negative results in bacterial mutagenicity tests with
and without metabolic activation.
t-Butanol: Studies using live animals suggest that tert-butanol is not
mutagenic.
No data available for the product.
Reproductive Toxicity:
THF: One animal study suggests that THF does not cause
reproductive effects at doses which are not maternally toxic.
12. ECOLOGICAL INFORMATION
Ecotoxicological Information:
Environmental toxicity testing of the product has not been carried out.
Tetrahydrofuran:
48 hr. LC50 = 2820; 2930 mg/l (orfe) [Handbook Env. Data on Org. Chem., 4th Ed]
96 hr. LC50 = 2160 mg/L (fathead minnow) [Handbook Env. Data on Org. Chem., 4th Ed]
t-butanol:
24-48 hr. EC50 = 5,504 mg/L (daphnia magna) [Handbook Env. Data on Org. Chem. 4th Ed.]
96 hr. LC50 = 6,410 mg/L (Leuciscus idus - orfe) [Handbook Env. Data on Org. Chem. 4th Ed.]
Chemical Fate Information:
No data available for the product. Lithium tri-tert-butoxyaluminum hydride reacts violently with water to form
hydrogen, lithium hydroxide and aluminum oxides.
Tetrahydrofuran: THF is expected to volatilize from both water and soil and leach into groundwater. It will not
photodegrade or adsorb to sediment. Limited evidence suggests it may biodegrade. Based on a relatively low Kow
(0.47), it is not expected to bioconcentrate.
t-Butanol: t-Butanol is expected to readily volatize from both water and soil. It is not expected to adsorb to sediment
or bioconcentrate in aquatic organisms. t-Butanol is expected to be very mobile in soil (estimated Koc of 36.9), and
may leach to groundwater. It is expected to biodegrade in both soil and groundwater. An estimated bioconcentration
factor (BCF) of 1.08 indicates a very low tendency to bioaccumulate. It is not expected to bioaccumulate (BCF 1.08).
13. DISPOSAL CONSIDERATIONS
Dispose of waste according to local and Federal laws and
DISPOSAL METHOD:
regulations.
14. TRANSPORT INFORMATION
UN3399
UN NUMBER:
Organometallic substance, liquid, water-reactive, flammable (Tri-tert-
PROPER SHIPPING NAME:
butoxyaluminum lithium hydride solution in tetrahydrofuran)
Dangerous when wet, 4.3 (3, Flammable liquid)
CLASSIFICATION:
Dangerous when wet, Flammable
LABELS:
I
PACKING GROUP:
-17 C (tetrahydrofuran)
FLASH POINT:
2931.00.9160
CUSTOM TARIFF NO:
No
MARINE POLLUTANT:
Not designated Poison Inhalation Hazard by US DOT.
PIH:
15. REGULATORY INFORMATION
Page 7 of 7
MSDS Ref. No: QS-MSD-221
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 2
UNITED STATES
SECTION 311 HAZARD CATEGORY (40 CFR 370): Fire hazard, immediate (acute) health hazard, reactive
This product contains t-butanol, which is a substance
SECTION 313 REPORTABLE INGREDIENTS (40
subject to the reporting requirements of Section 313 of the
CFR 372):
Emergency Planning and Community Right-to-Know act of
1986 and 40 CFR 372.
This information must be included in all MSDS's that are
copied and distributed for this material.
SECTION 302 EXTREMELY HAZARDOUS
SUBSTANCES (40 CFR 355): Not listed
CERCLA HAZARDOUS SUBSTANCE (40 CFR Tetrahydrofuran is listed. The reportable quantity is 1000
302.4): lbs.
TSCA SEC 12B EXPORT NOTIFICATION: This product is subject to TSCA 12(b) Export Notification
requirements due to the presence of tetrahydrofuran.
TSCA INVENTORY STATUS (40 CFR 710): Listed
Product Identification No.: 3399
CANADA
Hazard Classification: Class B, Division 2 (Flammable
WHMIS:
liquid)
Class B, Division 6 (Reactive Flammable Materials)
Class E, (Corrosive)
Ingredient Disclosure List: Tetrahydrofuran and t-butanol are
listed (1%)
16. OTHER INFORMATION
REVISION SUMMARY: Revision #2: Sections 2, 3, 9, 11, 14 & 16 revised. Regular review completed.
NFPA RATING HEALTH: 3
FLAMMABILITY: 4
REACTIVITY: 2
SPECIAL: W
This MSDS has been prepared to meet U. S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and
Canada's Workplace Hazardous Materials Information System (WHMIS) requirements.
type 2d
Copyright 2009. FMC Corporation, Lithium Division. All Rights Reserved. FMC Lithium and the FMC Lithium logo
are trademarks of FMC Corporation.
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