Page 1 of 6
MSDS Ref. No: QS-MSD-224
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 0
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Trimethylphosphine in toluene
PRODUCT NAME:
Organophosphine
CHEMICAL FAMILY:
C3 H9 P
MOLECULAR FORMULA:
For research and development use only.
GENERAL USE:
MANUFACTURER Emergency Telephone Numbers:
FMC CORPORATION CHEMTREC (800) 424-9300
Lithium Division Emergency Phone (704) 629-5361 (Plant) Call
P.O. Box 795 Collect 24 Hr/Day
Bessemer City, NC 28016-0795 Emergency Phone (303) 595-9048 (Medical)
General Information: (704) 868-5300 Call Collect
2. HAZARDS IDENTIFICATION
Flammable liquid; Category 2
CLASSIFICATION:
Skin irritant; Category 2
Toxic to reproduction; Category 2
Aspiration hazard; Category 1
Specific target organ systemic toxicity ?Single exposure; Category
3Specific target organ systemic toxicity ?Repeat exposure; Category 2
LABELING:
Flame, health hazard, exclamation mark
SYMBOLS:
Danger
SIGNAL WORD:
Highly flammable liquid and vapour
HAZARD STATEMENTS:
Causes skin irritation
Suspected of damaging the unborn child
May be fatal if swallowed and enters airways
May cause drowsiness or dizziness
May cause damage to organs through prolonged or repeated exposure
PRECAUTIONARY STATEMENTS: Prevention:
Keep away from heat/sparks/open flame- No smoking.
Keep container tightly closed.
Ground/Bond container and receiving equipment.
Use explosion-proof electrical, ventilation and lighting equipment.
Use only non-sparking tools.
Take precautionary measures against static discharge.
Wear chemical splash goggles with a face shield, chemical resistant
gloves (Viton) and clothing.
Wash thoroughly after handling.
Obtain special instructions before use.
Do not handle until all safety precautions have been read and
understood.
Use personal protective equipment as required.
Use only outdoors or in well-ventilated area.
Do not breathe vapours.
Response
In case of fire, use dry chemical for extinction. DO NOT USE WATER
OR CARBON DIOXIDE.
First Aid
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MSDS Ref. No: QS-MSD-224
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 0
See Section 4 of the MSDS.
Storage
See Section 7 of the MSDS.
Disposal
See Section 13 of the MSDS.
3. COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Name CAS # EC No Wt.% Classification, Hazard Statement
Codes
trimethylphosphine 594-09-2 209-823-1 5-10 Flam. liq. Cat. 2 H225
Skin Irrit. Cat. 2 H315
Toluene 108-88-3 203-625-9 85-95 Flam. liq. Cat. 2 H225
Repr. Cat 2 H361d
Asp. Tox. Cat. 1 H304
STOT RE Cat 2 H373
Skin Irrit. Cat 2 H315
STOT SE Cat. 3 H336
tetrahydrofuran 109-99-9 203-726-8 0-3 Flam. liq. Cat. 2 H225
Eye Irrit. Cat. 2 H319
STOT SE Cat. 3 H335
4. FIRST AID MEASURES
Immediately flush with water for at least 15 minutes, lifting the
EYES:
upper and lower eyelids intermittently. See a medical doctor or
ophthalmologist immediately
Quickly wipe off as much as possible, then immediately flush with
SKIN:
plenty of water while removing contaminated clothing and/or
shoes. Thoroughly wash with soap and water. Obtain immediate
medical attention. Contact a medical doctor if necessary.
Quickly wipe material from the mouth and rinse mouth with water.
INGESTION:
Do not induce vomiting. Never give anything by mouth to an
unconscious person. See a medical doctor immediately.
Remove to fresh air. If breathing discomfort occurs and persists,
INHALATION:
see a medical doctor. If breathing has stopped, give artificial
respiration and see a medical doctor immediately.
NOTES TO MEDICAL DOCTOR:
This product may be very irritating to the eyes, skin, respiratory and gastrointestinal tracts. Consideration should be
given to careful endoscopy as stomach or esophageal burns, perforations or strictures may occur. Careful gastric
lavage with an endotracheal tube in place should be considered. Observation may be warranted. Treatment is
controlled removal of exposure followed by symptomatic and supportive care.
5. FIRE FIGHTING MEASURES
Upper: 7.1% Lower: 1.1% (toluene)
FLAMMABLE LIMITS:
Flammable liquid. Air and oxygen sensitive.
GENERAL HAZARD:
Water spray, carbon dioxide, dry chemical powder or alcohol foam.
EXTINGUISHING MEDIA:
carbon dioxide, carbon monoxide, phosphorous oxides
HAZARDOUS COMBUSTION PRODUCTS:
Wear full protective clothing and self-contained breathing apparatus
FIRE FIGHTING PROCEDURES:
(SCBA) approved for fire fighting. This is necessary to protect against
the hazards of heat, products of combustion and oxygen deficiency.
Do not breathe smoke, gases or vapors generated.
Not available
AUTOIGNITION TEMPERATURE:
Air reactivity and volatility of solvents.
PROPERTIES CONTRIBUTING TO
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MSDS Ref. No: QS-MSD-224
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 0
FLAMMABILITY:
-20 C?br>
FLASH POINT:
Yes
SENSITIVITY TO STATIC DISCHARGE:
None
SENSITIVITY TO IMPACT:
COMMENTS:
(See Section 10, Stability and Reactivity)
6. ACCIDENTAL RELEASE MEASURES
Remove all sources of ignition. Contain spill with absorbant. Transfer
RELEASE NOTES:
to approved transport container and clean up spillage with an
absorbant. Dispose of waste according to local and Federal laws and
regulations.
Before cleanup measures begin, review the entire MSDS with
particular attention to Section 3, Emergency Overview and Potential
Health Effects; and Section 8, Recommended Personal Protective
Equipment.
7. HANDLING AND STORAGE
Use in a closed system under argon or nitrogen. Do not get in eyes,
HANDLING:
on skin or clothing. Do not breathe vapors or mist.
Store in a cool place. Keep container closed. Keep away from
STORAGE:
sources of ignition, air, acids and oxidizing agents.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE LIMITS
Chemical Name TWA STEL/Ceiling PEL STEL/Ceiling
(ACGIH) (ACGIH) (OSHA) (OSHA)
toluene 50 ppm 200 ppm 300 ppm
tetrahydrofuran 200 ppm 250 ppm 200 ppm
ENGINEERING CONTROLS:
Use in closed system under argon or nitrogen. If personal contact can occur, use local exhaust ventilation
(explosion-proof), to keep airborne concentrations below exposure limits.
PERSONAL PROTECTIVE EQUIPMENT
Chemical splash goggles with a face shield.
Eyes And Face:
When engineering controls are not adequate, wear a NIOSH/MSHA
Respiratory:
respirator approved for protection against organic vapors and mists.
Chemical resistant gloves and clothing.
Protective Clothing:
Quick-drench eyewash and safety shower.
Work Hygienic Practices:
9. PHYSICAL AND CHEMICAL PROPERTIES
Stench, odor of toluene and garlic like odor
ODOR:
Clear to milky white.
APPEARANCE:
Not available
pH:
100%
PERCENT VOLATILE:
Not available
VAPOR PRESSURE:
Not available
VAPOR DENSITY:
Toluene: 110 C
BOILING POINT:
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MSDS Ref. No: QS-MSD-224
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 0
Not available
MELTING POINT:
Insoluble in water
SOLUBILITY IN WATER:
Not available
EVAPORATION RATE(Butyl Acetate = 1):
0.854 g/cc
SPECIFIC GRAVITY:
76.08
MOLECULAR WEIGHT:
Not available
COEFF. OIL/WATER:
Not available
ODOR THRESHOLD:
Upper: 7.1% Lower: 1.1% (toluene)
FLAMMABLE LIMITS:
-20 C?br>
FLASH POINT:
Not available
AUTOIGNITION TEMPERATURE:
Not available
VISCOSITY:
Flammable liquid solvent
FLAMMABILITY:
Not available
DECOMPOSITION TEMPERATURE:
Not explosive
EXPLOSIVE PROPERTIES:
Not an oxidizer
OXIDIZING PROPERTIES:
10. STABILITY AND REACTIVITY
Heat, exposure to air.
CONDITIONS TO AVOID:
Stable at room temperature.
STABILITY:
Does not polymerize
POLYMERIZATION:
Not available
HAZARDOUS DECOMPOSITION
PRODUCTS:
Heat, fire, air and oxidizing chemicals. Reacts violently with
INCOMPATIBLE MATERIALS:
halogenated hydrocarbons.
11. TOXICOLOGICAL INFORMATION
Product is expected to be extremely irritating or
Eye Contact:
corrosive.
Toluene: Irritant
No data available for the product.
Skin Contact:
Toluene: Irritant
No data available for the product.
Skin Absorption:
Toluene:
Dermal LD50 =14100 uL/kg (rabbit) [RTECS]
No data available for the formulation.
Ingestion:
Toluene: Oral LD50 = 636 mg/kg (rat) [RTECS]
No data available for the formulation.
Inhalation:
Toluene: LC50 = 49 gm/m3/4H (rat) [RTECS]
Acute Effects From Overexposure:
May be extremely irritating to eyes, skin and respiratory system. Stench. Inhalation of vapors may cause dizziness,
nausea, anesthesia, numbness, motor weakness in fingers and toes, incoordination, and headache. If ingested,
may produce a lung aspiration hazard.
Chronic Effects From Overexposure:
No data available for the formulation.
Toluene: Possible reproductive hazard - may cause developmental toxicity, based on animal information. Toluene
was not carcinogenic in mice and rats exposed by inhalation to up to 1200 ppm for 24 months. Prolonged skin
exposure may result in dermatitis. Symptoms observed in laboratory animals following subchronic inhalation
exposure to toluene has caused narcosis, tremors and anesthesia in laboratory animals.
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MSDS Ref. No: QS-MSD-224
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 0
No data available for product.
Sensitization:
Toluene: Not expected to be sensitizing.
EH40: Not listed
Carcinogenicity:
IARC: Toluene is listed as Group 3, unclassifiable as to
carcinogenicity to humans.
NTP: Not listed
OSHA: Not considered a carcinogen under OSHA.
ACGIH: Toluene is listed as Category A4, not classifiable as a
human carcinogen.
No data available for product.
Mutagenicity:
No data available for product.
Reproductive Toxicity:
Toluene: Possible reproductive hazard - may cause developmental
toxicity, based on animal information.
12. ECOLOGICAL INFORMATION
Ecotoxicological Information:
No data available for product.
Toluene:
24-96 hour LC50 = 56-34 mg/L (fathead minnow) [Handbook of Env Data on Organic Chem, 4th Ed.]
24-96 hour LC50 = 24 mg/L (bluegill) [Handbook of Env Data on Organic Chem, 4th Ed.]
48 hr. EC50 = 15 mg/L (daphnia magna) [Handbook of Env Data on Organic Chem, 4th Ed.]
Chemical Fate Information:
No data available for product. Trimethylphosphine reacts with air to form phosphine oxides.
Toluene: Toluene biodegrades slowly and volatilizes rapidly from soil. It is not expected to bioconcentrate.
13. DISPOSAL CONSIDERATIONS
Dispose of waste according to local and Federal laws and
DISPOSAL METHOD:
regulations.
14. TRANSPORT INFORMATION
UN1993
UN NUMBER:
Flammable liquids, N. O. S. (trimethylphosphine in toluene)
PROPER SHIPPING NAME:
Flammable
CLASSIFICATION:
Flammable
LABELS:
II
PACKING GROUP:
-20 C?br>
FLASH POINT:
2942.00.0000
CUSTOM TARIFF NO:
No
MARINE POLLUTANT:
Not designated Poison Inhalation Hazard by US DOT.
PIH
15. REGULATORY INFORMATION
UNITED STATES Immediate (acute) health hazard, delayed (chronic) health
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MSDS Ref. No: QS-MSD-224
Version: US/Canada
Date Approved: 03/15/2009
Revision No: 0
hazard, fire hazard, reactive
SECTION 311 HAZARD CATEGORY (40 CFR 370):
This product contains toluene which is subject to the
SECTION 313 REPORTABLE INGREDIENTS (40
reporting requirements of Section 313 of the Emergency
CFR 372):
Planning and Community Right-To-Know Act of 1986.
This information must be included in all MSDS's that are
copied and distributed for this material.
SECTION 302 EXTREMELY HAZARDOUS
SUBSTANCES (40 CFR 355): Not listed
CERCLA HAZARDOUS SUBSTANCE (40 CFR Toluene and tetrahydrofuran are listed. The reportable
302.4): quantity is 1000 pounds.
TSCA SEC 12B EXPORT NOTIFICATION: This product is subject to TSCA 12(b) Export Notification
requirements due to the presence of tetrahydrofuran.
This product is for research and development purposes
TSCA INVENTORY STATUS (40 CFR 710):
only, and not for commercial use. Trimethylphosphine is not
listed on the TSCA Inventory. Toluene and tetrahydrofuran
are listed.
Product Identification No.: 1993
CANADA
Hazard Classification: Class B, Division 6 (Reactive
WHMIS:
Flammable Materials)
Class E, (Corrosive)
Class D2A, (Teratogenicity and embryotoxicity - very toxic -
other)
Ingredient Disclosure List: Toluene and tetrahydrofuran are
listed
16. OTHER INFORMATION
REVISION SUMMARY: Revision # 1: Sections 2, 3, 9, 11, 14 & 16 revised. Regular review completed.
NFPA RATING HEALTH: 3
FLAMMABILITY: 3
REACTIVITY: 2
SPECIAL: none
This MSDS has been prepared to meet U. S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and
Canada's Workplace Hazardous Materials Information System (WHMIS) requirements.
type 2g
Copyright 2009. FMC Corporation, Lithium Division. All Rights Reserved. FMC Lithium and the FMC Lithium logo
are trademarks of FMC Corporation.
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