MATERIAL SAFETY DATA SHEET (MSDS)
MATERIAL SAFETY DATA SHEET
EM SCIENCE
|1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Manufacturer.............: Preparation Date.: 8/6/99
EM SCIENCE
A Division of EM Industries Information Phone Number.: 856-423-6300
P.O. Box 70 Hours: Mon. to Fri. 8:30-5
480 Democrat Road Chemtrec Emergency Number: 800-424-9300
Gibbstown, N.J. 08027 Hours: 24 hrs a day
Catalog Number(s):
TX0277 TX0278 TX0279 TX0279AP TX0280 TX0280AG TX0280GS
TX0280P TX0280T TX0281 TX0282 TX0282AG TX0282P TX0284
Product Name:
Tetrahydrofuran
Synonyms:
THF; Diethylene oxide; Tetramethylene oxide
Chemical Family:
Cyclic Ether
Formula:
C4H8O
Molecular Weight.:
72.11
2. COMPOSITION / INFORMATION ON INGREDIENTS
Component CAS # Appr %
____________________________________________________________
Tetrahydrofuran
109-99-9 100%
3. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
EXTREMELY FLAMMABLE LIQUID AND VAPOR.
TENDS TO FORM EXPLOSIVE PEROXIDES ESPECIALLY WHEN ANHYDROUS.
CAUSES IRRITATION OF EYES, NOSE AND THROAT.
MAY CAUSE EYE INJURY.
May Cause Damage To Nervous and Respiratory Systems, Kidneys and Liver.
Appearance:
Colorless liquid; ethereal odor
POTENTIAL HEALTH EFFECTS (ACUTE AND CHRONIC)
Symptoms of Exposure:
Irritating to eyes (causing blurred vision), skin, respiratory tract (anesthetic effect, headache) May cause damage to nervous
and respiratory systems, kidneys and liver. May cause eye burns.
Medical Cond. Aggravated by Exposure:
Pre-existing skin disorders or eye
problems or impaired liver or kidney functions.
Routes of Entry:
Inhalation, ingestion
Carcinogenicity:
The material is not listed (IARC, NTP, OSHA) as cancer causing
agent.
4. FIRST AID MEASURES
Emergency First Aid:
GET MEDICAL ASSISTANCE FOR ALL CASES OF OVEREXPOSURE.
Skin: Immediately flush thoroughly with large amounts of water.
Eyes: Immediately flush thoroughly with water for at least 15
minutes.
Inhalation: Remove to fresh air; give artificial respiration if
breathing has stopped.
Ingestion: Do not induce vomiting; if conscious, give water
freely and get medical attention.
5. FIRE FIGHTING MEASURES
Flash Point (F): 6F (tcc)
Flammable Limits LEL (%): 2
Flammable Limits UEL (%): 11.8
Extinguishing Media:
Use carbon dioxide or dry chemical. Use water to cool fire-exposed
containers and disperse vapors.
Fire Fighting Procedures:
Wear self-contained breathing apparatus and protective clothing.
Fire & Explosion Hazards:
Dangerous fire and explosive hazard. Explosive peroxides may form after long storage or exposure to air and light. THF can
form heat sensitive peroxide which may explode on concentration by distillation or drying. Do not distill or allow THF, or
solutions containing THF, to dry if tests show more than 0.05% THF peroxide present. To avoid a possible explosion, THF
should never be distilled to dryness. Vapor can travel distances to ignition source and flash back.
6. ACCIDENTAL RELEASE MEASURES
Spill Response:
Evacuate the area of all unnecessary personnel. Wear suitable protective equipment listed under Exposure / Personal
Protection. Eliminate any ignition sources until the area is determined to be free from explosion or fire hazards. Contain the
release and eliminate its source, if this can be done without risk. Take up and containerize for proper disposal as described
under Disposal. Comply with Federal, State, and local regulations on reporting releases. Refer to Regulatory Information for
reportable quantity and other regulatory data.
EM SCIENCE recommends Spill-X absorbent agents for various types of spills. Additional information on the Spill-X
products can be provided through the EM SCIENCE Technical Service Department (609) 423-6300. The following EM
SCIENCE Spill-X absorbent is recommended for this product:
SX0863 Solvent Spill Treatment Kit
7. HANDLING AND STORAGE
Handling & Storage:
Keep container closed. Store in a cool area away from ignition sources and oxidizers. Check peroxide content before heating
material. Do not get in eyes, on skin, or on clothing. Do not breathe vapor.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
ENGINEERING CONTROLS AND PERSONAL PROTECTIVE EQUIPMENT:
Ventilation, Respiratory Protection, Protective Clothing, Eye Protection:
Respiratory Protection: If workplace exposure limit(s) of product or any component is exceeded (see TLV/PEL), a
NIOSH/MSHA approved air supplied respirator is advised in absence of proper environmental control. OSHA regulations
also permit other NIOSH/MSHA respirators (negative pressure type) under specified conditions (see your safety equipment
supplier). Engineering and/or administrative controls should be implemented to reduce exposure. Material should be handled
or transferred in an approved fume hood or with adequate ventilation. Protective gloves (PVA or equivalent) should be worn
to prevent skin contact. Coverall chemical splash goggles must be worn at all times.
Work/Hygenic Practices:
Wash thoroughly after handling. Do not take internally. Eye wash and safety equipment should be readily available.
EXPOSURE GUIDELINES
OSHA - PEL:
TWA STEL CL
Component PPM MG/M3 PPM MG/M3 PPM MG/M3 Skin
____________________________________________________________
Tetrahydrofuran
200 590 250 735
ACGIH - TLV:
TWA STEL CL
Component PPM MG/M3 PPM MG/M3 PPM MG/M3 Skin
____________________________________________________________
Tetrahydrofuran
200 590 250 737
If there are no exposure limit numbers listed in the Exposure Guidelines chart, this indicates that no OSHA or ACGIH
exposure limts have been established.
9. PHYSICAL AND CHEMCIAL PROPERTIES
Boiling Point (C 760 mmHg) : 65C
Melting Point (C) : -108.5C
Specific Gravity (H2 0 = 1) : 0.888
Vapor Pressure (mm Hg) : 114 15C
Percent Volatile by vol (%): 100%
Vapor Density (Air = 1) : 2.5
Evaporation Rate (BuAc = 1): 8.0
Solubility in Water (%) : Soluble
Appearance :
Colorless liquid; ethereal odor
10. STABILITY AND REACTIVITY
Stability: Yes
Hazardous Polymerization:
Does not occur
Hazardous Decomposition:
COx
Conditions to Avoid:
Heat; contact with ignition sources; evaporation to dryness or near dryness
Materials To Avoid:
( ) Water
( ) Acids
( ) Bases
( ) Corrosives
( ) Oxidizers
(X) Other: Strong oxidizers, sodium aluminum hydride,
excess of strong caustic, lithium aluminum hydride
11. TOXICOLOGICAL INFORMATION
Toxicity Data
ihl-hmn TCLo: 25000 ppm
orl-rat LD50: 1650 mg/kg
ihl-rat LD50: 21000 ppm/3H
Toxicological Findings:
Test on laboratory animals indicate material may produce adverse
mutagenic and reproductive effects.
Cited in Registry of Toxic Effects of Chemical Substances (RTECS)
12. DISPOSAL CONSIDERATIONS
EPA Waste Numbers: U213 D001
Treatment:
Incineration, fuels blending or recycle. Contact your local permitted waste disposal site (TSD) for permissible treatment sites.
ALWAYS CONTACT A PERMITTED WASTE DISPOSER (TSD) TO ASSURE COMPLIANCE WITH ALL
CURRENT LOCAL, STATE AND FEDERAL REGULATIONS.
13. TRANSPORT INFORMATION
DOT Proper Shipping Name:
Tetrahydrofuran
DOT ID Number :
UN2056
14. REGULATORY INFORMATION
TSCA Statement:
The CAS number of this product is listed on the TSCA Inventory.
SARA SARA CERCLA
Component EHS EHS TPQ RQ
(302) (lbs) (lbs)
____________________________________________________________
Tetrahydrofuran
1000
OSHA SARA
DeMinimis
Component Floor List 313
for SARA 313
(%)
____________________________________________________________
Tetrahydrofuran
Y
If there is no information listed on the regulatory information chart, this indicates that the chemical is not covered by the
specific regulation listed.
15. OTHER INFORMATION
Comments:
none
NFPA Hazard Ratings:
Health :2
Flammability :3
Reactivity :1
Special Hazards :
Revision History: 8/1/81 4/15/86 6/8/87 10/27/89
1/30/91 3/1/91 7/26/94 4/5/95 7/7/95 8/28/95 2/15/96
2/11/97
| = Revised Section
N/A = Not Available
N/E = None Establised
The statements contained herein are offered for informational purposes only and are based upon technical data that EM
Science believes to be accurate. It is intended for use only by persons having the necessary technical skill and at their own
discretion and risk. Since conditions and manner of use are outside our control, we make NO WARRANTY, EXPRESS OR
IMPLIED, OR MERCHANTABILITY, FITNESS OR OTHERWISE.
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