Inco 庐
Jinco Nonferrous Metals Co. Ltd. China
INCOMOND Nickel Chloride
Hazardous Ingredients
Inco PEL1鈥搈g/m3 TLV1,2 鈥搈g/m3
Hazardous Ingredients C.A.S. No
Nickel Chloride Hexahydrate
7791-20-0 1 as NI 0.1* as Ni
(NiCl2 鈥? 6H2O)
Material Physical and Chemical Data
Yellow or light green deliquescent Crystals
Safety Specific
Ingredient Mol. Wt. m.p.掳C b.p.掳C Sol. In H20 g/100ml
Gravity
NiCl2 鈥? 6H2O 237.7 n.av. n.av. n.av. >250 in cold water
Data Physical Hazards
Stable under normal ambient conditions. Prevent contact with skin and eyes. Do not ingest or inhale
Sheet (dust). Solutions of the product are acidic. Substance will pick up moisture from the air and become
soluble if exposed to humid air. Substance can become liquid at >40潞C. At high temperatures, >400潞C,
toxic gases containing chlorine may be evolved.
Health Hazards
Nickel Chloride, Hexahydrate
LD50 ORAL RAT : 200 mg/kg
The International Agency for Research on Cancer (IARC) [4] in 1990 and
Inhalation:
the U.S.Tenth Report on Carcinogens [5] in 2002 concluded there was
sufficient evidence that nickel compounds are carcinogenic to humans.
In 1999 Toxicology Excellence for Risk Assessment (TERA) found that
carcinogenic risk from soluble nickel compounds via inhalation cannot
be determined (Class D) because the existing evidence is composed of
conflicting data.(6)
Epidemiological studies of Norwegian nickel refinery workers showed
that an increased risk of respiratory cancer was present in electrolysis
plant workers. These workers had mixed exposure to aerosols of nickel
sulfate and nickel chloride and to insoluble forms of nickel. Electrolysis
plant workers in an Ontario refinery similarly exposed to nickel sulfate
and nickel chloride aerosols, but not the dust from matte roasting
operations did not show any increased incidence of respiratory cancer.
There is no evidence from animal studies that soluble nickel compounds
are carcinogenic by relevant routes of exposure. Exposure to aerosols of
nickel chloride causes irritation of the upper respiratory tract and
maycause asthma.
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Skin Contact: Repeated contact with aerosols and solutions of nickel chloride can
cause skin irritation, nickel sensitivity and allergic skin rashes.
Eye Contact: May cause irritation
Ingestion: Ingestion of relatively large doses of solutions of nickel chloride may
cause nausea, vomiting and diarrhea. The U.S. Food and Drug
Administration has affirmed that nickel is generally recognized as safe
(GRAS) as a direct human food ingredient. The U.S. National Institute
for Occupational Safety and Health concluded that there is no evidence
that nickel and its inorganic compounds are carcinogenic by route of
Inco ingestion.
Pre-existing Conditions: Skin contact can cause an allergic rash and/or asthma in previously
Material sensitized individuals.
Reproductive Toxicity: Animal experiments indicate that soluble nickel ingestion causes
adverse effects on fetal development at a threshold oral exposure of 2.2
Safety mg/ Ni/kg/day by pregnant rats. Data are insufficient to determine if this
effect occurs in humans and no regulatory agency has classified soluble
forms of nickel as reproductive risks for humans.
Precautions for Safe Storage, Handling and Use
Data
Do not inhale dust or mist containing nickel chloride. Keep container closed when not in use. Ventilation is
normally required when handling or using this product to keep exposures below the PEL. If ventilation
Sheet alone cannot so control exposure, use NIOSH-approved respirators selected according to local regulatory
standards. Maintain airborne nickel levels as low as possible.
Avoid skin or eye contact. Wear suitable eye protection and gloves. Wash skin thoroughly after handling,
and before eating, drinking or smoking. Launder clothing and gloves as needed.
Do not store near chemical bases or oxidizing materials. Protect container against physical damage.
Store in cool, well-ventilated space.
Spill, Leak and Disposal Procedure
Do not allow spills to enter water courses. Collect spill of dry nickel chloride crystals by sweeping with
sweeping compound or by vacuuming with the vacuum exhaust passing through a high efficiency
particulate arresting (HEPA) filter if the vacuum exhaust is discharged into the workplace. Leaked or
spilled solutions should be treated with lime and the solids recovered.
Wear appropriate NIOSH-approved respirators if collection and disposal of spills is likely to cause the
concentration of airborne nickel to exceed the PEL.
Nickel-containing material is normally collected to recover nickel values. Should disposal be deemed
necessary, follow local regulations.
Emergency and First Aid Procedures
In case of contact with eyes, immediately flush eyeballs with plenty of water for 15 minutes. Seek
medical attention immediately. In case of accidental ingestion, drink large quantities of water. Seek
medical attention.
In case of skin contact, wash skin thoroughly with water. For rashes, seek medical advice. Cleanse
wounds thoroughly to remove any nickel chloride particles.
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Notes and Bibliography
Inco believes that the information in this Material Safety Data Sheet is accurate. However, Inco
makes no express or implied warranty as to the accuracy of such information and expressly disclaims
any liability resulting from reliance on such information.
Manufactured by:
Jinco Nonferrous Metals Co., Ltd.,
No. 159 Qing Yang South Road
Inco Kunshan Economic & Technical Development Zone
Kunshan City 215300
Jiangshu, P.R. China.
Emergency Telephone No., 0086 {0}512 57712666 Ext., 806.
Material Under licence from, INCO Limited
Footnotes :
庐 Trademark of the Inco family of companies.
Safety 1 OSHA Permissible Exposure Limit
2 Threshold Limit Value of the American Conference of Governmental Industrial Hygienists.
Data 3 Describes possible health hazards of the product supplied. If user operations change it to other
chemical forms, whether as end products, intermediates or fugitive emissions, the possible health
hazards of such forms must be determined by the user.
Sheet 4 IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 49, World Health
Organization, 1990
U.S. National Toxicology Program (NTP), 鈥?10th Report on Carcinogens, December 2002
5
6 Toxicology Excellence for Risk Assessment (TERA), 鈥淭oxicological Review of Soluble Nickel
Salts鈥?. Report prepared for US EPA, Health Canada and the Metal Finishing Association of
Southern California, March 1999.
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