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HYCOR BIOMEDICAL INC.
MATERIAL SAFETY DATA SHEET
Date updated: 30 May, 2006
Version: 02.03
SECTION 1. PRODUCT AND COMPANY IDENTIFICATION
Commercial Product: KOVA Stain
Name: KOVA Stain
List Number(s): 87116, 87116E
Product Classification: Component of in vitro diagnostic device
Manufacture Company:
Hycor Biomedical Inc. Hycor Biomedical GmbH Hycor Biomedical, Ltd.
7272 Chapman Ave. Otto-Hahn Stra脽e 16 Pentland Science Park
Garden Grove, CA 92841(USA) 34123 Kassel, Germany Bush Loan, Penicuik EH26 OPL
United Kingdom
Emergency Telephone No.:
USA (714) 933-3000 Attention: Randy Wilson
Germany: 49 561 959 46
United Kingdom: 44 131 445 7111
SECTION 2. CHEMICAL CHARACTERIZATION/INFORMATION ON INGREDIENTS
Character: Bottles contain <1% Reagent Alcohol, <0.3% Glycerol, < 0.1% Ammonium Oxalate, <0.3% Safranin O, and
<0.1% Crystal Violet.
Hazardous substances: Safranin O, Crystal violet, ammonium oxalate.
See EEC directive 67/548 and amendments
Substance %w/w Health Class CAS No. EINECS No. ANNEX 1
Safranin O Solution
(alcohol methylique) <0.3% Xn R:10-20/21/22- 477-73-6 207-518-8
40/20/21/22
S:16-36/37-45
Ammonium Oxalate <0.1% C R: 21/22
S: 24/25 6009-70-7 238-135-4 607-007-00-3
Crystal Violet <0.1% R: 22-40-41-50/53
S: 22-26-36/37/39-61 548-62-9 208-953-6
See section 16 for spelling of R and S phrases.
SECTION 3. HAZARDS IDENTIFICATION
Classification: Harmful if swallowed, risk of serious damage to eyes, corrosive, flammable.
Warnings: May cause irritation to respiratory system and skin.
Contact with eyes: Vapor may cause severe irritation and eye damage.
Inhalation: Vapor or mist cause irritation to the respiratory tract. Do not breathe fumes.
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Commercial Product: KOVA Stain
SECTION 4. FIRST AID MEASURES
Eye Contact: Promptly wash eyes with copious water for at least 15 minutes. Assure flushing by separating the eyelids
with fingers. Call physician.
Skin Contact: Wash area with copious amount of water for at least 15 minutes. Remove contaminated clothing and
shoes. Call a physician.
Ingestion: Wash out mouth with water provided person is conscious. Consult physician or poison control center.
Inhalation: Remove to fresh air. If not breathing gives artificial respiration. If breathing is difficult give oxygen, call a
physician.
SECTION 5. FIRE-FIGHTING MEASURES
Extinguishing Media: Dry chemical powder, carbon dioxide, or water spray.
Special Fire Fighting Procedures: Wear self-contained breathing apparatus and protective clothing to prevent contact
with skin and eyes.
Unusual Fire Fighting Procedures: Keep away from heat, sparks and flames.
Thermal Decomposition: Emits toxic fumes under fire conditions.
SECTION 6. ACCIDENTAL RELEASE MEASURES
Steps To Be Taken After Spillage: Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves as
specified in Section 8. Absorb liquid spills with a dry absorbent and place in a waste container for disposal. Wash area with
dilute bleach or soap. Ventilate area of leak or spill.
Absorbent Material: Vermiculite, dry sand, earth or similar material
Waste Disposal Method: Consult a specialist for disposal of spilled substance.
SECTION 7. HANDLING AND STORAGE
Handling: Keep in its original container, tightly closed. Protect from physical damage. Open and handle container carefully.
Use in a chemical fume hood. Wear heavy rubber gloves, safety goggles and protective clothing. Do not swallow.
Do not breathe vapor. Avoid contact with eyes and skin.
Storage: Room temperature.
Other Precautions: Store away from any area where the fire hazard may be acute.
SECTION 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Product TLV: Not known.
Respiratory Protection: NIOSH/MSHA-approved respirator.
Eye Protection: Chemical safety goggles.
Hand Protection: Wear compatible chemical-resistant gloves. Wash hands before breaks and at end of the work.
Other Protective Equipment: Keep container closed. Keep away from heat, sparks, and open flame. Use nonsparking tools.
Wear lab coat, apron or coveralls to prevent skin contact.
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Commercial Product: KOVA Stain
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid Ignition Temperature: N/A
Color: Dark purple liquid Explosion limits: N/A
Odor: Slight alcohol odor. Vapor Pressure: N/A
pH Value: 5 to 7 Solubility In Water: Soluble
In Alcohol: Yes
Viscosity: N/A
SECTION 10. STABILITY AND REACTIVITY
Stability: Stable under ordinary conditions of use and storage.
Condition to avoid: Do not refrigerate or freeze.
Incompatibilities: Oxidizing agents, peroxides, acids, alkali metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide and nitrogen oxide.
Hazardous Polymerization: Will not occur.
SECTION 11. TOXICOLOGICAL INFORMATION
Refer to the product: Referred to Safranin O solution (in pure form)
LD50 Oral (rat): 5628 mg/kg
LD50 Oral: Not known
LD50 Skin (rabbit): 15800mg/kg
LC50 Inhalation (rat): 64000 ppm/4 hr.
LD50 Skin: Not known
Irritation, skin (rabbit): 20 mg /24h mod.
Irritation, eyes (rabbit): 100 mg/24h mod.
LD50 Inhalation: Not known
IARC category: 3 (not classified as a human carcinogen)
Irritation, skin: Not known
Referred to Crystal violet (in pure form)
Irritation, eyes: Not known
LD50 Oral (rat): 420 mg/kg
LD50 Skin (rabbit): not known
LC50 Inhalation (rat): not known
Irritation, skin (human): 2 mg /2 days mld.
Toxicological Information: Product is harmful if swallowed, inhalation, or skin absorption. Causes eye irritation.
SECTION 12. ECOLOGICAL INFORMATION
Use product according with good laboratory practices and avoid releasing to the environment.
Data not yet available. Other adverse effects: None
SECTION 13. DISPOSAL CONSIDERATIONS
Observe all Federal, State and Local laws concerning Health and Pollution.
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Commercial: KOVA Stain
SECTION 14. TRANSPORT INFORMATION
Transport in accordance with national and international regulations.
It is not subject to current regulations for transportation of hazardous goods (GGUS/A DR, GGVE/RID, IMDG, IATA/ICAD)
Do not compromise container integrity.
SECTION 15. REGULATORY INFORMATION
Label information:
Hazard Symbol: none
Indication of danger: none
Risk phrases: none
Safety phrases: none
SECTION16. OTHER INFORMATION
The information herein is believed to be correct as of the date hereof but is provided without warranty of any kind. The
recipient of our products is responsible for observing any laws and guidelines applicable.
Legend:
R phrases:
R 10: Flammable
R 20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R 40/20/21/22: Harmful: Possible risk of irreversible effects through inhalation, in contact with skin and if swallowed.
R 40: Risk of evidence of carcinogenic effect.
R 41: Risk of serious damage to eyes
R 50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
S phrases:
S 16: Keep away from sources of ignition-no smoking.
S 36/37: Wear suitable protecting clothing and gloves.
S 22: Do not breathe dust.
S 24/25: Avoid contact with skin and eyes.
S 26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S 36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S 61: Avoid release to the environment. Refer to special instructions/safety data sheets
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