#9903 MSDS Material Safety Data Sheet (MSDS) for
U0126 (MEK1/2 Inhibitor) 166B Cummings Center I Beverly, MA 01915
Orders I 877-616-CELL (2355) Support I 877-678-TECH (8324) Web I www.cellsignal.com
orders@cellsignal.com info@cellsignal.com
Swallowing: May be harmful if swallowed.
I. Identification
Skin absorption: May be harmful if absorbed through the skin.
Product name: U0126 (MEK1/2 Inhibitor)
Inhalation: May be harmful if inhaled. Material may be irritating to
Chemical name: 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio) mucous membranes and upper respiratory tract.
butadiene
Skin contact: May be harmful.
CAS number: 109511-58-2
Eye contact: May cause eye irritation.
Empirical formula: C18 H16 N6 S2
Chronic effects of overexposure: May be harmful.
Molecular weight: 380.50
Emergency and First Aid Procedures
Chemical family: Aromatic aminothiol Swallowing鈥擶ash out mouth with water, provided person is conscious.
Call a physician.
II. Physical Data Skin鈥擨n case of contact, immediately wash skin with soap and copious
amounts of water.
Boiling point: N/A (solid compound)
Inhalation鈥擨f inhaled, remove to fresh air. If breathing becomes difficult,
Melting point: 172鈥?173掳C call a physician.
Specific gravity: N/A (solid compound) Eyes鈥擨n case of contact with eyes, flush with copious amounts of water
for at least 15 minutes. Assure adequate flushing by separating eyelids with
Vapor density: N/A (solid compound)
fingers. Consult a physician.
Percent volatile by volume: N/A (solid compound)
Freezing point: Solid at working temperatures.
VI. Reactivity Data
Vapor pressure at 20掳C: N/A (solid compound)
Stability/Conditions to avoid: Not reactive as far as is known.
Solubility in water: Not readily soluble.
Incompatibility/Materials to avoid: Strong oxidizing agents; sensitive
to light.
Appearance: White to off-white solid.
Combustion/Decomposition products: Carbon monoxide, carbon
dioxide, nitrogen oxides, sulfur oxides.
III. Ingredients
Hazardous polymerization: Not susceptible to polymerization.
Material: Supplied as pure compound.
VII. Spill or Leak Procedures
IV. Fire and Explosion Hazard Data
Steps to be taken if material is spilled or released: Wear self-con-
Flash point: N/A (solid compound)
tained breathing apparatus, rubber boots and rubber gloves. Sweep up,
Extinguishing media: Fire extinguishing media should match other place in bag and dispose of properly. Wash spill site after sweeping up.
materials in fire.
Waste disposal method: Dissolve the material in a combustible solvent
Special fire fighting procedures: If involved in fire, don NIOSH/MSHA- and burn in an EPA-licensed chemical incinerator equipped with an after-
approved self-contained breathing apparatus, flame/chemical resistant. burner and scrubber.
Unusual fire and explosion hazards: Emits toxic fumes under fire
conditions. VIII. Special Protection Information
Respiratory protection: Avoid inhalation. Use NIOSH/MSHA-approved
V. Health Hazard Data respirator.
Threshold Limit Value (TLV) and source: Data not available. Ventilation: Use mechanical exhaust.
漏 2001 Cell Signaling Technology, Inc.
Acute effects of overexposure: May cause skin irritation. To the best of Protective equipment: Wear suitable protective clothing, chemical
our knowledge, the chemical, physical and toxicological properties have resistant gloves and lab safety glasses.
not been thoroughly investigated.
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#9903 MSDS
166B Cummings Center I Beverly, MA 01915
Orders I 877-616-CELL (2355) Support I 877-678-TECH (8324) Web I www.cellsignal.com
orders@cellsignal.com info@cellsignal.com
IX. Special Precautions
Precautions to be taken in handling and storage: This compound is
sold only for research use by personnel familiar with the toxicology of
organic chemicals and who are well trained in good laboratory habits, such
as avoiding spills, keeping hands clean at all times and not rubbing eyes
with hands while working in the laboratory.
This compound is sold only in milligram quantities for use in dilute solu-
tions in biological research. No other use is intended, and any other use
may involve substantial hazards.
This compound is to be stored as tightly stoppered solutions kept under
nitrogen or argon, or kept as supplied in a sealed glass ampule.
The above information is believed to be correct but does not purport to be
all inclusive and shall be used only as a guide for experienced personnel.
Cell Signaling Technology, Inc., shall not be held liable for any damage
resulting from the handling of or from contact with the above product. The
burden of safe use of this material rests entirely with the user.
Revised: July 2001
漏 2001 Cell Signaling Technology, Inc.
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