CHLOROBENZENE http://www.jtbaker.com/msds/C2475.htm
CHLOROBENZENE
MSDS Number: C2475 --- Effective Date: 04/04/00
1. Product Identification
Synonyms: Monochlorobenzene; Chlorobenzol; Phenyl chloride; Benzene chloride
CAS No.: 108-90-7
Molecular Weight: 112.56
Chemical Formula: C6H5Cl
Product Codes:
J.T. Baker: 9179
Mallinckrodt: 4419, 4426
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Chlorobenzene 108-90-7 99 - 100% Yes
3. Hazards Identification
Emergency Overview
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WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED OR
INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
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AFFECTS CENTRAL NERVOUS SYSTEM AND LIVER.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER.
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath.
Affects central nervous system causing dizziness, incoordination and unconsciousness.
Ingestion:
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.
Toxic! May cause systemic poisoning with symptoms paralleling those of inhalation.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain. May be slowly absorbed
through the skin with possible systemic effects.
Eye Contact:
Vapors cause eye irritation. Splashes cause severe irritation, possible corneal burns and eye
damage.
Chronic Exposure:
Prolonged or repeated skin exposure may cause dermatitis or skin burns. Prolonged or repeated
exposure may cause liver, kidney, or lung damage.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin, eye or central nervous system disorders, or impaired liver, kidney,
or pulmonary function may be more susceptible to the effects of this substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get
medical attention.
Skin Contact:
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Immediately flush skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly
clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: 28C (82F) CC
Autoignition temperature: 593C (1099F)
Flammable limits in air % by volume:
lel: 1.3; uel: 9.6
Flammable Liquid
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Reactions
with incompatibles may pose an explosion hazard. Vapors can flow along surfaces to distant ignition
source and flash back. Sealed containers may rupture when heated. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposed containers
cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse
vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing
apparatus with full facepiece operated in the pressure demand or other positive pressure mode. This
highly flammable liquid must be kept from sparks, open flame, hot surfaces, and all sources of heat
and ignition. Combustion by-products include phosgene and hydrogen chloride gases.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective
equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected
personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g.,
vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible
materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray
to disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from
exposures. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in
excess of reportable quantities. The toll free number for the US Coast Guard National Response
Center is (800) 424-8802.
J. T. Baker SOLUSORB(R) solvent adsorbent is recommended for spills of this product.
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7. Handling and Storage
Protect against physical damage. Outside or detached storage is preferred. Inside storage should be
in a standard flammable liquids storage room or cabinet. Separate from oxidizing materials. Storage
and use areas should be No Smoking areas. Containers should be bonded and grounded for
transfers to avoid static sparks. Containers of this material may be hazardous when empty since
they retain product residues (vapors, liquid); observe all warnings and precautions listed for the
product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
75 ppm (TWA)
-ACGIH Threshold Limit Value (TLV):
10 ppm (TWA)
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the
Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended
Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face organic vapor respirator may be worn for up to ten
times the exposure limit or the maximum use concentration specified by the appropriate regulatory
agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may
be worn up to 50 times the exposure limit or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or
instances where the exposure levels are not known, use a full-face piece positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in
oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash
fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
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Appearance:
Clear, colorless liquid.
Odor:
Faint, almond like odor.
Solubility:
Insoluble in water.
Specific Gravity:
1.11 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
132C (270F)
Melting Point:
-45C (-49F)
Vapor Density (Air=1):
3.9
Vapor Pressure (mm Hg):
11.8 @ 25C (77F)
Evaporation Rate (BuAc=1):
1.1
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
May produce carbon monoxide, carbon dioxide, hydrogen chloride and phosgene when heated to
decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Oxidizing agents, dimethyl sulfoxide, silver perchlorate, silver chromate.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
For Chlorobenzene: Oral rat LD50: 1110 mg/kg; Inhalation rat LC50: 2965 ppm. Investigated as a
tumorigen, mutagen, reproductive effector.
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--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Chlorobenzene (108-90-7) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this material may evaporate to a moderate extent. When released into
the soil, this material is not expected to biodegrade. When released into the soil, this material may
leach into groundwater. When released to water, this material is expected to quickly evaporate.
When released into the water, this material is expected to have a half-life of less than 1 day. When
released into water, this material is not expected to biodegrade. This material is not expected to
significantly bioaccumulate. When released into the air, this material may be moderately degraded
by reaction with photochemically produced hydroxyl radicals. When released into the air, this
material is expected to have a half-life between 1 and 10 days.
Environmental Toxicity:
The LC50/96-hour values for fish are between 10 and 100 mg/l. This material is expected to be
slightly toxic to aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and
sent to a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing,
use or contamination of this product may change the waste management options. State and local
disposal regulations may differ from federal disposal regulations. Dispose of container and unused
contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: RQ, CHLOROBENZENE
Hazard Class: 3
UN/NA: UN1134
Packing Group: III
Information reported for product/size: 52L
International (Water, I.M.O.)
-----------------------------
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Proper Shipping Name: CHLOROBENZENE
Hazard Class: 3
UN/NA: UN1134
Packing Group: III
Information reported for product/size: 52L
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: CHLOROBENZENE
Hazard Class: 3
UN/NA: UN1134
Packing Group: III
Information reported for product/size: 52L
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Chlorobenzene (108-90-7) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Chlorobenzene (108-90-7) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Chlorobenzene (108-90-7) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Chlorobenzene (108-90-7) 100 U037 Yes
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2Y
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products
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Regulations (CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning:
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED OR
INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
AFFECTS CENTRAL NERVOUS SYSTEM AND LIVER.
Label Precautions:
Keep away from heat, sparks and flame.
Avoid breathing vapor.
Keep container closed.
Wash thoroughly after handling.
Avoid contact with eyes, skin and clothing.
Use only with adequate ventilation.
Label First Aid:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. If swallowed, give large amounts of water to drink. Never give anything by mouth to an
unconscious person. In case of contact, immediately flush eyes or skin with plenty of water for at
least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. In all
cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 4, 11, 14, 16.
Disclaimer:
*****************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but
makes no representation as to its comprehensiveness or accuracy. This document is
intended only as a guide to the appropriate precautionary handling of the material by a
properly trained person using this product. Individuals receiving the information must
exercise their independent judgment in determining its appropriateness for a particular
purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR
WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT
LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH
HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE
FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
*****************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
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