SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 16/FEB/2005
Date Updated: 25/MAY/2004
Version 1.2
According to 91/155/EEC
1 - Product and Company Information
Product Name CADMIUM, SHOT, CA. 3MM, 99.999%
Product Number 202886
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CADMIUM 7440-43-9 231-152-8 None
Formula Cd
Molecular Weight 112.4 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Not hazardous according to Directive 67/548/EC.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Exercise appropriate precautions to minimize direct contact with
skin or eyes and prevent inhalation of dust.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 0.01
Poland NDSCh -
Poland NDSP -
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Wear dust mask.
Hand Protection: Protective gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 765 掳C
MP/MP Range 320.9 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
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Explosion Limits N/A
Vapor Pressure N/A
SG/Density 8.65 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Oxidizing agents, Acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Cadmium/cadmium oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
ACUTE TOXICITY
LCLO
Inhalation
Human
39 mg/m3
20M
Remarks: Cardiac:Other changes. Vascular:Thrombosis distant from
injection site. Lungs, Thorax, or Respiration:Respiratory
depression.
LD50
Oral
Rat
2330 mg/kg
LC50
Inhalation
Rat
25 mg/m3
30M
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
LD50
Oral
Mouse
890 mg/kg
LD50
Intraperitoneal
Mouse
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5700 UG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Acute inhalation exposure to cadmium fumes may cause "metal fume
fever" with flu-like symptoms of weakness, fever, headache,
chills, nausea, vomiting, dizziness, sweating, muscular pain,
cough and difficulty breathing. Acute pulmonary edema may
develop within 24 hours and reaches a maximum by three days.The
first chronic effect of exposure to cadmium is generally kidney
damage, manifested by excretion of excessive protein in the
urine, followed by anemia, teeth discoloration and loss of
smell. Cadmium also is believed to cause pulmonary emphysema and
bone disease.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Woman
Route of Application: Inhalation
Exposure Time: 20Y-
Result: Tumorigenic:Carcinogenic by RTECS criteria. Lungs,
Thorax, or Respiration:Tumors.
Rat
Route of Application: Subcutaneous
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Tumorigenic:Tumors at site or application.
Rat
Route of Application: Intramuscular
Exposure Time: 4W
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Musculoskeletal:Tumors. Tumorigenic:Tumors at site or
application.
Rat
Route of Application: Unreported
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Tumorigenic Effects: Testicular tumors.
Tumorigenic:Tumors at site or application.
Rat
Route of Application: Intramuscular
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Blood:Lymphomas including Hodgkin's disease.
Tumorigenic:Tumors at site or application.
Rat
Route of Application: Intramuscular
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Blood:Lymphomas including Hodgkin's disease.
Tumorigenic:Tumors at site or application.
Rat
Route of Application: Intramuscular
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Exposure Time: 4W
Result: Tumorigenic:Neoplastic by RTECS criteria.
Musculoskeletal:Tumors. Tumorigenic:Tumors at site or
application.
IARC CARCINOGEN LIST
Rating: Group 1
CHRONIC EXPOSURE - MUTAGEN
Mouse
6 UMOL/L
Cell Type: Embryo
Micronucleus test
Hamster
1 UMOL/L
Cell Type: ovary
Cytogenetic analysis
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 220 MG/KG
Route of Application: Oral
Exposure Time: (1-22D PREG)
Result: Effects on Embryo or Fetus: Other effects to embryo.
Species: Rat
Dose: 23 MG/KG
Route of Application: Oral
Exposure Time: (1-22D PREG)
Result: Specific Developmental Abnormalities: Blood and
lymphatic system (including spleen and marrow).
Species: Rat
Dose: 1250 UG/KG
Route of Application: Intravenous
Exposure Time: (14D PREG)
Result: Specific Developmental Abnormalities: Body wall.
Specific Developmental Abnormalities: Urogenital system.
Species: Rat
Dose: 1250 UG/KG
Route of Application: Intravenous
Exposure Time: (9D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system. Specific Developmental Abnormalities: Eye, ear.
Species: Rat
Dose: 8 MG/KG
Route of Application: Intravenous
Exposure Time: (8-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
Species: Mouse
Dose: 448 MG/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATIONS)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
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e.g., stunted fetus). Effects on Embryo or Fetus: Fetal death.
Species: Mouse
Dose: 1686 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (7D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system.
Species: Hamster
Dose: 2 MG/KG
Route of Application: Parenteral
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Craniofacial
(including nose and tongue).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 155 MG/KG
Route of Application: Oral
Exposure Time: (13W MALE/13W PRE-3W PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Behavioral.
Species: Rat
Dose: 21500 UG/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATIONS)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Newborn: Germ cell
effects (in offspring).
Species: Rat
Dose: 1124 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (1D MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Rat
Dose: 250 UG/KG
Route of Application: Subcutaneous
Exposure Time: (19D PREG)
Result: Effects on Newborn: Biochemical and metabolic.
Species: Mouse
Dose: 1700 MG/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
Result: Effects on Newborn: Viability index (e.g., # alive at
day 4 per # born alive). Effects on Newborn: Growth statistics
(e.g., reduced weight gain).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
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Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
Not hazardous according to Directive 67/548/EC.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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