SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 16/FEB/2005
Date Updated: 12/MAR/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name BUTYRYL CHLORIDE, 99+%
Product Number 236349
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
BUTYRYL CHLORIDE 141-75-3 205-498-5 607-136-00-5
Formula C4H7ClO
Molecular Weight 106.55 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Causes burns.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER EYE CONTACT
Assure adequate flushing of the eyes by separating the eyelids
with fingers.
5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Water hydrolyzes material liberating acidic gas which in contact
with metal surfaces can generate flammable and/or explosive
hydrogen gas.
EXTINGUISHING MEDIA
Suitable: Carbon dioxide.
Unsuitable: Do not use water.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Vapor may travel
considerable distance to source of ignition and flash back.
Emits toxic fumes under fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame. Store in a cool dry place.
Incompatible Materials: Do not allow contact with water
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Remove and wash contaminated
clothing promptly.
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
Appearance Color: Colorless
Form: Clear liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 98 - 102 掳C
MP/MP Range -89 掳C
Flash Point 18 掳C Method: closed cup
Flammability N/A
Autoignition Temp 280 掳C
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Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.5 %
Upper: 7.3 %
Vapor Pressure 39 mmHg 20 掳C
SG/Density 1.018 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 3.7 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Other Solvents: MISCIBLE WITH ETHER
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Alcohols, Oxidizing agents, Strong bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
11 - Toxicological Information
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Multiple Routes: Harmful if swallowed, inhaled, or absorbed
through skin. Causes burns.
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
Test Type: LC50 Fish
Species: Brachydanio rerio
Time: 96 h
Value: 215 - 464 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
The material should be ignited in the presence of sodium carbonate
and slaked lime (calcium hydroxide). The substance should be mixed
with vermiculite and then with the dry caustics, wrapped in paper
and burned in a chemical incinerator equipped with an afterburner
and scrubber. Observe all federal, state, and local environmental
ALDRICH - 236349 www.sigma-aldrich.com Page 3
regulations.
14 - Transport Information
RID/ADR
UN#: 2353
Class: 3
PG: II
Proper Shipping Name: Butyryl chloride
IMDG
UN#: 2353
Class: 3
PG: II
Subrisk: 8
Proper Shipping Name: Butyryl chloride
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2353
Class: 3
PG: II
Subrisk: 8
Proper Shipping Name: Butyryl chloride
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 607-136-00-5
INDICATION OF DANGER: F C
Highly Flammable. Corrosive.
R-PHRASES: 11 34
Highly flammable. Causes burns.
S-PHRASES: 16 23 26 36 45
Keep away from sources of ignition - no smoking. Do not breathe
vapor. In case of contact with eyes, rinse immediately with
plenty of water and seek medical advice. Wear suitable
protective clothing. In case of accident or if you feel unwell,
seek medical advice immediately (show the label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 3
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
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Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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