SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 20/FEB/2005
Date Updated: 13/MAR/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name CADMIUM OXIDE, 99.99+%
Product Number 202894
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CADMIUM OXIDE BROWN 1306-19-0 215-146-2 048-002-00-0
Formula CdO
Molecular Weight 128.4 AMU
Synonyms Cadmium monoxide * Cadmium oxide (ACGIH) * Kadmu
tlenek (Polish) * NCI-C02551
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer by inhalation. Also harmful if swallowed. Also
toxic: danger of serious damage to health by prolonged exposure
through inhalation and if swallowed.
Carc. Cat.2
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
5 - Fire Fighting Measures
EXPLOSION DATA
Dust Potential: This material, like most materials in powder
form, is capable of creating a dust explosion.
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use extinguishing media appropriate to
surrounding fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves. Wear disposable coveralls and discard them after
use.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store in a cool dry
place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.01 mg/m3
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 0.02 mg/m3
Remarks: KT
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 0.002 mg/m3
Remarks: A M K
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 0.025 mg/m3
OEL STEL 0.05 mg/m3
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
Appearance Form: Powder
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Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 8.15 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.
11 - Toxicological Information
RTECS NUMBER: EV1925000
ACUTE TOXICITY
LD50
Oral
Rat
72 mg/kg
LD50
Intraperitoneal
Rat
12 MG/KG
LD50
Intravenous
Rat
25 MG/KG
LD50
Oral
Mouse
72 mg/kg
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LC50
Inhalation
Mouse
250 mg/m3
2H
LD50
Subcutaneous
Mouse
94 MG/KG
LC50
Inhalation
Dog
4,000 mg/m3
10M
LC50
Inhalation
Monkey
1,500 mg/m3
10M
LC50
Inhalation
Rabbit
2,500 mg/m3
10M
LC50
Inhalation
Guinea pig
3,500 mg/m3
10M
LD50
Oral
Mammal
72 mg/kg
SIGNS AND SYMPTOMS OF EXPOSURE
Damage to the kidneys. Damage to the lungs. Exposure can cause:
ROUTE OF EXPOSURE
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract.
Multiple Routes: May be fatal if inhaled, swallowed, or absorbed
through skin. Causes eye and skin irritation.
TARGET ORGAN INFORMATION
Damage to the kidneys. Damage to the lungs. Kidneys. Lungs.
CHRONIC EXPOSURE - CARCINOGEN
Result: Carcinogen.
Rat
Route of Application: Subcutaneous
Result: Tumorigenic:Neoplastic by RTECS criteria.
Tumorigenic:Tumors at site or application.
IARC CARCINOGEN LIST
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Rating: Group 1
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 21640 UG/KG
Route of Application: Oral
Exposure Time: (1-19D PREG)
Result: Effects on Embryo or Fetus: Maternal-fetal exchange.
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus). Effects on Embryo or Fetus: Fetal death.
Species: Rat
Dose: 21640 UG/KG
Route of Application: Oral
Exposure Time: (1-19D PREG)
Result: Specific Developmental Abnormalities: Cardiovascular
(circulatory) system. Effects on Newborn: Weaning or lactation
index (e.g., # alive at weaning per # alive at day 4). Effects
on Newborn: Growth statistics (e.g., reduced weight gain).
Species: Rat
Dose: 91 UG/M3
Route of Application: Inhalation
Exposure Time: (1-19D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
Species: Rat
Dose: 2 MG/M3/6H
Route of Application: Inhalation
Exposure Time: (4-19D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Musculoskeletal system.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 183 UG/M3/5H
Route of Application: Inhalation
Exposure Time: (21W PRE/1-20D PREG)
Result: Effects on Newborn: Viability index (e.g., # alive at
day 4 per # born alive). Effects on Newborn: Growth statistics
(e.g., reduced weight gain).
Species: Rat
Dose: 23 UG/M3/5H
Route of Application: Inhalation
Exposure Time: (21W PRE/1-20D PREG)
Result: Effects on Newborn: Behavioral.
Species: Rat
Dose: 16 UG/M3/24H
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Mouse
Dose: 2 MG/M3/6H
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Route of Application: Inhalation
Exposure Time: (4-17D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus). Specific Developmental Abnormalities:
Musculoskeletal system.
Species: Mouse
Dose: 500 UG/M3/6H
Route of Application: Inhalation
Exposure Time: (4-17D PREG)
Result: Effects on Fertility: Mating performance (e.g., # sperm
positive females per # females mated; # copulations per # estrus
cycles). Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
CMR CAT.: Carc. Cat.2
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2570
Class: 6.1
PG: III
Proper Shipping Name: Cadmium compound
IMDG
UN#: 2570
Class: 6.1
PG: III
Proper Shipping Name: Cadmium compound
Marine Pollutant: No
Severe Marine Pollutant: Yes
IATA
UN#: 2570
Class: 6.1
PG: III
Proper Shipping Name: Cadmium compound
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 048-002-00-0
NOTA: E
INDICATION OF DANGER: T
Toxic.
R-PHRASES: 49 22 48/23/25
May cause cancer by inhalation. Also harmful if swallowed. Also
toxic: danger of serious damage to health by prolonged exposure
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through inhalation and if swallowed.
S-PHRASES: 53 45
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible).
SWITZERLAND
SWISS POISON CLASS: 1
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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