SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 20/FEB/2005
Date Updated: 16/MAR/2004
Version 1.1
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name CADMIUM SULFATE, 99.999%
Product Number 481882
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CADMIUM SULFATE ANHYDROUS 10124-36-4 233-331-6 048-009-00-9
Formula CdSO4
Molecular Weight 208.46 AMU
Synonyms Cadmium sulphate * Sulphuric acid, cadmium salt
(1:1)
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause cancer by inhalation. Also harmful if swallowed. Also
toxic: danger of serious damage to health by prolonged exposure
through inhalation and if swallowed. Very toxic to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
Carc. Cat.2
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use extinguishing media appropriate to
surrounding fire conditions.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Explosion Hazards: Container explosion may occur under fire
conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves. Wear disposable coveralls and discard them after
use.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store in a cool dry
place.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.01 mg/m3
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 0.03 mg/m3
Remarks: E M K
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.025MG(CD)/M3
Remarks: Carcinogen.
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
Appearance N/A
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Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 4.69 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Cadmium/cadmium oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: EV2700000
ACUTE TOXICITY
LD50
Oral
Rat
280 mg/kg
LD50
Oral
Mouse
88 mg/kg
LD50
Intraperitoneal
Mouse
6879 UG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Damage to the lungs. Damage to the kidneys. Symptoms of exposure
may include burning sensation, coughing, wheezing, laryngitis,
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shortness of breath, headache, nausea, and vomiting.
ROUTE OF EXPOSURE
Skin Absorption: May be harmful if absorbed through the skin.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: Harmful if swallowed.
Multiple Routes: Causes eye and skin irritation.
TARGET ORGAN INFORMATION
Damage to the lungs. Damage to the kidneys. Lungs. Kidneys.
Prostate. Blood.
CHRONIC EXPOSURE - CARCINOGEN
Result: This is or contains a component that has been reported
to be carcinogenic based on its IARC, OSHA, ACGIH, NTP, or EPA
classification.
IARC CARCINOGEN LIST
Rating: Group 1
CHRONIC EXPOSURE - MUTAGEN
Human
500 UMOL/L
Cell Type: lymphocyte
DNA damage
Rat
30 UMOL/L
Cell Type: liver
DNA damage
Mouse
4300 UG/KG
Intraperitoneal
Micronucleus test
Mouse
150 UG/L
Cell Type: lymphocyte
Mutation in mammalian somatic cells.
Hamster
1 UMOL/L
Cell Type: ovary
Other mutation test systems
Hamster
1 UMOL/L
Cell Type: ovary
Cytogenetic analysis
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 35230 MG/KG
Route of Application: Oral
Exposure Time: (1-19D PREG)
Result: Specific Developmental Abnormalities: Cardiovascular
(circulatory) system. Effects on Newborn: Weaning or lactation
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index (e.g., # alive at weaning per # alive at day 4). Effects
on Newborn: Growth statistics (e.g., reduced weight gain).
Species: Mouse
Dose: 5150 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Effects on Embryo or Fetus: Other effects to embryo.
Species: Mouse
Dose: 3 MG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system.
Species: Mouse
Dose: 1030 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
Species: Mouse
Dose: 2570 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system.
Species: Mouse
Dose: 28 UG/KG
Route of Application: Parenteral
Exposure Time: (12D PREG)
Result: Effects on Embryo or Fetus: Fetal death. Specific
Developmental Abnormalities: Craniofacial (including nose and
tongue). Specific Developmental Abnormalities: Musculoskeletal
system.
Species: Hamster
Dose: 2800 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Other
developmental abnormalities.
Species: Hamster
Dose: 2 MG/KG
Route of Application: Intravenous
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system. Specific Developmental Abnormalities: Homeostasis
Specific Developmental Abnormalities: Craniofacial (including
nose and tongue).
Species: Hamster
Dose: 2 MG/KG
Route of Application: Intravenous
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system. Specific Developmental Abnormalities: Craniofacial
(including nose and tongue). Specific Developmental
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Abnormalities: Eye, ear.
Species: Hamster
Dose: 2 MG/KG
Route of Application: Intravenous
Exposure Time: (8D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Homeostasis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 35230 MG/KG
Route of Application: Oral
Exposure Time: (1-19D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Fertility:
Post-implantation mortality (e.g., dead and/or resorbed implants
per total number of implants). Effects on Embryo or Fetus:
Maternal-fetal exchange.
Species: Mouse
Dose: 5150 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (9D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Species: Hamster
Dose: 2 MG/KG
Route of Application: Intravenous
Exposure Time: (8D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Specific Developmental Abnormalities: Eye, ear. Specific
Developmental Abnormalities: Central nervous system.
CMR CAT.: Carc. Cat.2
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2570
Class: 6.1
PG: III
Proper Shipping Name: Cadmium compound
IMDG
UN#: 2570
Class: 6.1
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PG: III
Proper Shipping Name: Cadmium compound
Marine Pollutant: No
Severe Marine Pollutant: Yes
IATA
UN#: 2570
Class: 6.1
PG: III
Proper Shipping Name: Cadmium compound
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 048-009-00-9
NOTA: E
INDICATION OF DANGER: T N
Toxic. Dangerous for the environment.
R-PHRASES: 49 22 48/23/25 50/53
May cause cancer by inhalation. Also harmful if swallowed. Also
toxic: danger of serious damage to health by prolonged exposure
through inhalation and if swallowed. Very toxic to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
S-PHRASES: 53 60 45 61
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. This material and its
container must be disposed of as hazardous waste. In case of
accident or if you feel unwell, seek medical advice immediately
(show the label where possible). Avoid release to the
environment. Refer to special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 1
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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