The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
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Vertrel(R) CCA
6169FR Revised 22-MAY-2001
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
Formula : CF3CHFCHFCF2CF3, CF3CH2CF2CH3,
CClH=CClH(TRANS)
Tradenames and Synonyms
"VERTREL"
KCD-9583
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont Fluoroproducts
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
138495-42-8
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (HFC-43- 32-34
10mee)
406-58-6
1,1,1,3,3-PENTAFLUOROBUTANE (HFC-365mfc) 27-29
TRANS, 1,2-DICHLOROETHYLENE (t-DCE) 156-60-5 38-40
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HAZARDS IDENTIFICATION
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Potential Health Effects
Gross overexposure by inhalation to HFC-43-10mee may cause
suffocation if air is displaced by vapors and central
nervous system stimulation with increased activity or
sleeplessness, tremors or convulsions. These effects may be
followed by central nervous system depression with
6169FR DuPont Page 2
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
dizziness, confusion, incoordination, drowsiness or
unconsciousness. Based on data from other fluorocarbons,
gross overexposure to HFC-43-10mee may cause irregular heart
beat with a strange sensation in the chest, "heart thumping"
apprehension, lightheadedness, feeling of fainting,
dizziness, weakness, sometimes progressing to loss of
consciousness and death. Intentional misuse or deliberate
inhalation may cause death without warning. Vapor reduces
oxygen available for breathing and is heavier than air.
Immediate effects of overexposure to HFC-43-10mee by skin
contact may include slight irritation with itching, redness
or swelling. Repeated and/or prolonged exposure may cause
defatting of the skin with itching, redness or rash. Based
on animal data, significant skin permeation, and systemic
toxicity after skin contact, appears unlikely. Immediate
effects of overexposure to HFC-43-10mee by eye contact may
include eye irritation with tearing, pain or blurred vision.
The major ingestion hazard of HFC-43-10mee is aspiration
(liquid entering the lungs during ingestion or vomiting)
which may result in "chemical pneumonia." Symptoms include
coughing, gasping, choking, shortness of breath, bluish
discoloration of the skin, rapid breathing and heart rate,
and fever. Pulmonary edema or bleeding, drowsiness,
confusion, coma and seizures may occur in more serious
cases. Symptoms may develop immediately or as late as 24
hours after exposure, depending on how much chemical entered
the lungs. Increased susceptibility to the effects of
HFC-43-10mee may be observed in persons with pre-existing
disease of the central nervous system or the cardiovascular
system.
Based on animal data, HFC-365mfc may cause eye irritation
with tearing, pain or blurred vision. Repeated skin contact
may cause drying and cracking. Inhalation of HFC-365mfc may
cause central nervous system depression with dizziness,
confusion, incoordination, drowsiness or unconsciousness.
Gross overexposure by inhalation may cause irregular heart
beat with a strange sensation in the chest, "heart
thumping", apprehension, lightheadedness, feeling of
fainting, dizziness, weakness, sometimes progressing to loss
of consciousness and death.
Inhalation of t-DCE may cause central nervous system
depression with dizziness, confusion, incoordination,
drowsiness or unconsciousness; or tremors, nausea, vomiting,
weakness, and abdominal cramps. Other effects may include
irregular heart beat with a strange sensation in the chest,
"heart thumping",apprehension, lightheadedness, feeling of
fainting, dizziness, or weakness. Skin contact with t-DCE
may cause severe irritation with burning, redness, swelling,
pain or rash. Eye contact with t-DCE may cause severe eye
irritation with tearing, pain or blurred vision. Ingestion
of t-DCE may cause pulmonary edema (body fluid in the lungs)
with cough, wheezing, abnormal lung sounds, possibly
6169FR DuPont Page 3
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
progressing to severe shortness of breath and bluish
discoloration of the skin: symptoms may be delayed.
Ingestion may also cause pathological changes in the liver,
central nervous system depression with dizziness, confusion,
incoordination, drowsiness or unconsciousness, and
structural (pathological) changes in heart muscle tissue.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
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FIRST AID MEASURES
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First Aid
INHALATION
If inhaled, immediately remove to fresh air. Keep person calm.
If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Call a physician.
SKIN CONTACT
Flush skin with water after contact. Wash contaminated clothing
before reuse.
EYE CONTACT
In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Call a physician.
INGESTION
If swallowed, do not induce vomiting. Immediately give 2 glasses
of water. Never give anything by mouth to an unconscious person.
Call a physician.
Notes to Physicians
Activated charcoal mixture may be beneficial. Suspend 50 g
activated charcoal in 400 mL water and mix well. Administer 5
mL/kg, or 350 mL for an average adult.
THIS MATERIAL MAY MAKE THE HEART MORE SUSCEPTIBLE TO ARRHYTHMIAS.
Catecholamines such as adrenaline, and other compounds having
similar effects, should be reserved for emergencies and then used
only with special caution.
6169FR DuPont Page 4
Material Safety Data Sheet
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FIRE FIGHTING MEASURES
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Flammable Properties
Flammable limits in Air, % by Volume
LEL : 7.5 %
UEL :9%
Flash Point : None
Method : Pensky Marten Closed Cup (ASTM D 93)
Fire and Explosion Hazards:
Use water spray or fog to cool containers. Drums may
rupture under fire conditions. Decomposition may occur.
Extinguishing Media
Use media appropriate for surrounding material.
Fire Fighting Instructions
Evacuate personnel to a safe area. Wear self-contained breathing
apparatus (SCBA) and full protective equipment.
Self-contained breathing apparatus (SCBA) is required if
drums rupture and contents are spilled under fire
conditions.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Initial Containment
Dike spill. Prevent material from entering sewers, waterways, or
low areas.
Spill Clean Up
Immediately evacuate the area and provide maximum
ventilation, especially in low places where heavy vapors
might collect. Unprotected personnel should move upwind of
spill. Only personnel equipped with proper respiratory and
skin/eye protection should be permitted in area. Soak up
with sawdust, sand, oil dry or other absorbent material.
After all visible traces, including ignitable vapors, have
been removed, thoroughly wet vacuum the area. Do not flush
to sewer. If area of spill is porous, remove as much
contaminated earth and gravel, etc. as necessary and place
6169FR DuPont Page 5
Material Safety Data Sheet
(ACCIDENTAL RELEASE MEASURES - Continued)
in closed containers for disposal.
In spill or leak situations, the composition of vapors above
the liquid may fall within the LEL/UEL and, therefore,
become flammable. Provide ventilation and assure no
ignition sources are present.
Accidental Release Measures
Ventilate area, especially low places where heavy vapors
might collect. In spill or leak situations, the composition
of vapors above the liquid may fall within the LEL/UEL and
therefore become flammable. Provide ventilation and assure
no ignition sources are present.
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HANDLING AND STORAGE
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Handling (Personnel)
Avoid breathing vapors or mist. Avoid contact with eyes, skin, or
clothing. Wash thoroughly after handling.
The use of gloves is recommended when working with the
material containers. Material should not be dispensed from
its container by pouring, except for small sample containers
where fume hoods or where other ventilation is used to
manage the exposure limits. The use of a drum pump is
recommended for dispensing from shipping containers.
Storage
Store in a clean, dry area. Do not allow stored product to
exceed 52 C (125 F) to prevent leakage or potential rupture
of container from pressure and expansion. Protect from
freezing temperatures. If solvent is stored below -10 C (14
F), mix prior to use.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls
Use only with adequate ventilation. Keep containers tightly
closed. Vapors are heavier than air posing a hazard of
asphyxia if they are trapped in enclosed or low places.
Mechanical ventilation should be used in low or enclosed
places.
Personal Protective Equipment
EYE/FACE PROTECTION
Wear safety glasses or coverall chemical splash goggles.
6169FR DuPont Page 6
Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
RESPIRATORS
Where there is potential for airborne exposures in excess of
applicable limits, wear NIOSH approved respiratory protection.
PROTECTIVE CLOTHING
Where there is potential for skin contact have available and wear
as appropriate impervious gloves, apron, pants and jacket.
Protective gloves and chemical splash goggles should be used
when handling liquid.
# Exposure Guidelines
Applicable Exposure Limits
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (HFC-43-10mee)
PEL (OSHA) : None Established
TLV (ACGIH) : None Established
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA
400 ppm, Ceiling
1,1,1,3,3-PENTAFLUOROBUTANE (HFC-365mfc)
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA
TRANS, 1,2-DICHLOROETHYLENE (t-DCE)
PEL (OSHA) : 200 ppm, 790 mg/m3, 8 Hr. TWA
TLV (ACGIH) : 200 ppm, 8 Hr. TWA
AEL * (DuPont) : 200 ppm, 8 & 12 Hr. TWA
* AEL is DuPont's Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Boiling Point : 37 C (99 F)
Freezing Point : -35 C (-31 F)
Vapor Pressure : 488 mm Hg @ 25 C (77 F)
pH : 7.1
Odor : Ethereal.
Form : Liquid.
Color : Colorless.
Specific Gravity : 1.34
Density : 1.35 g/cm3 @ 25 C (77 F)
11.3 lb/gal
6169FR DuPont Page 7
Material Safety Data Sheet
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STABILITY AND REACTIVITY
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Chemical Stability
Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials
Incompatible with alkali or alkaline earth metals - powdered
Al, Zn, Be, Na, Mg, etc.
Incompatible with strong bases such as NaOH, KOH, etc.
Decomposition
Decomposes with heat. High temperatures can decompose
HFC-43-10mee and HFC-365mfc (open flames, glowing metal
surfaces, etc.) forming hydrofluoric acid and possibly
carbonyl fluoride.
HFC-43-10mee and HFC-365mfc are incompatible with strong
bases and can react to form salts of hydrofluoric acid and
unsaturated compounds of unknown toxicity.
1,2-Trans DCE is unstable at high temperatures and will form
hydrochloric acid and unsaturates as well as break down or
react in the presence of caustic to form salts of
hydrochloric acid.
Polymerization
Polymerization will not occur.
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TOXICOLOGICAL INFORMATION
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Animal Data
HFC-43-10mee:
Oral LD50: > 5,000 mg/kg in rats
Dermal ALD: > 5,000 mg/kg in rabbits
Inhalation, 4 hour LC50: 11,100 ppm in rats
HFC-365mfc:
Inhalation LC50: > 100,000 ppm in rats
Oral LD50: > 2000 mg/kg in rats
t-DCE:
Oral LD50: 1275 mg/kg in rats
Dermal LD50: > 5000 mg/kg in rabbits
Inhalation LC50, 4 hr: 24,100 ppm in rats
6169FR DuPont Page 8
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
Animal testing indicates that HFC-43-10mee is a slight skin
irritant and a mild eye irritant, but is not a skin
sensitizer. Single exposure to 5,000 ppm HFC-43-10mee by
inhalation caused tremors. A different single exposure
study by inhalation in rats caused incoordination,
hyperactivity and prostration; pathological examination of
rats from this study revealed kidney and lung changes, and
external hair loss. Repeated exposures to 1,900 - 3,500 ppm
caused tremors or convulsions, behavioral effects, and
altered clinical chemistry. These effects were temporary.
In a different repeated exposure test the
No-Observed-Adverse-Effect-Level (NOAEL) for convulsions was
1000 ppm. Results indicate convulsions is an acute effect
of HFC-43-10mee. The 90-day No-Observed-Adverse-Effect-Level
(NOAEL) is 500 ppm. In animal testing HFC-43-10mee produced
developmental effects only at exposure levels producing
other toxic effects in the adult animal. No animal data are
available to define the carcinogenic or reproductive hazards
of HFC-43-10mee. Tests have shown that HFC-43-10mee does
not cause genetic damage in bacterial or mammalian cell
cultures. It has not produced genetic damage in tests on
animals.
HFC-365mfc is not a skin irritant or skin sensitizer, but is
a slight eye irritant in tests on animals. A 28-day repeated
inhalation exposure to 9685, 24,747 and 50,486 ppm caused
decreased body weight gain at the high dose and increased
urinary fluoride output in the medium and high dose groups.
Ameloblastic anemia in the teeth also occurred in the high
dose group. No effects were produced on clinical chemical
or hematological parameters. Other effects include cardiac
sensitization, a potentially fatal disturbance of heart
rhythm associated with a heightened sensitivity to the
action of epinephrine. The NOEL for this effect is 46,800
ppm in dogs. No animal data are available to define
carcinogenic, developmental or reproductive effects of
HFC-365mfc. Tests have shown that HFC-365mfc does not cause
genetic damage in bacterial cell cultures or in an in vivo
mouse micronucleus test.
t-DCE is a severe eye irritant, and a moderate to severe
skin irritant. Single and repeated exposure to t-DCE by
ingestion caused increased kidney weight, histopathological
changes of the lungs, liver effects, decreased motor
activity, pulmonary edema, cardiovascular system changes,
and mortality. Single and repeated exposure to t-DCE by
inhalation caused pathological changes of the liver and
lungs, inactivity or anaesthesia, altered white blood cell
count, cardiovascular system changes and weak cardiac
sensitization, a potentially fatal disturbance of the heart
rhythm caused by a heightened sensitivity to the action of
epinephrine. Long-term exposure caused altered liver and
lung function. A more recent inhalation study (Dec. 1998)
conducted with well-characterized t-DCE containing > 99.4%
6169FR DuPont Page 9
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
t-DCE, produced no adverse, compound-related effects. The
NOEL was 4000 ppm. Exposure of pregnant rats shows maternal
toxicity at 2000, 6000 and 12,000 ppm. Developmental
toxicity was seen only at 12,000 ppm. Tests have shown that
t-DCE does not cause genetic damage in bacterial or
mammalian cell cultures. No animal data are available to
define the carcinogenic or reproductive hazards of t-DCE.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity:
HFC-43-10mee:
96 hour LC50 in fathead minnows: 27.2 mg/L
96 hour LC50 in rainbow trout: 13.9 mg/L
48 hour LC50 in Daphnia magna: 11.7 mg/L
HFC-365mfc:
96 hour LC50 in Zebra fish: > 200 mg/L.
48 hour NOEC in Daphnia magna: >200 mg/L
72 hour NOEC in Algae (S. cppricornutum): 113 mg/L
t-DCE:
96 hour LC50 in bluegill sunfish: 1350 mg/L
48 hour LC50 in Daphnia magna: 220 mg/L
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DISPOSAL CONSIDERATIONS
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Waste Disposal
Treatment, storage, transportation, and disposal must be in
accordance with applicable Federal, State/Provincial, and Local
regulations.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO/IATA - Not regulated in containers with less than 25
lbs. If greater than 2500 lbs., use:
Proper Shipping Name: Environmentally Hazardous Substance,
Liquid, N.O.S.
(Trans-1,2-Dichloroethylene)
Hazard Class: 9
UN Number: 3082
6169FR DuPont Page 10
Material Safety Data Sheet
(TRANSPORTATION INFORMATION - Continued)
Packing Group: III
Reportable Quantity: 1000 lbs.(Trans-1,2-Dichloroethylene)
2500 lbs.("Vertrel" KCD-9583)
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REGULATORY INFORMATION
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U.S. Federal Regulations
TSCA Inventory Status : Listed.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No
1,1,1,2,2,3,4,5,5,5-DECAFLUOROPENTANE (CAS# 138495-42-8) is
controlled by TSCA Section 5, Significant New Use Rule
(SNUR; 40 CFR 721.5645) The approved uses are: precision and
general cleaning, carrier fluid, displacement drying,
printed circuit board cleaning, particulate removal and film
cleaning, process medium, heat transfer fluid (dielectric
and non-dielectric), and test fluid. Processors and users
of this substance must also comply with the applicable
general SNUR requirements set forth in 40 CFR 721 subpart A
and the applicable record keeping requirements set forth at
40 CFR 721.125.
LISTS:
SARA Extremely Hazardous Substance -No
CERCLA Hazardous Substance -Yes*
*1,2 Dichloroethylene Component Only
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NPCA-HMIS Rating
Health :1
Flammability :0
Reactivity :1
Personal Protection rating to be supplied by user depending on use
conditions.
6169FR DuPont Page 11
Material Safety Data Sheet
(Continued)
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The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : MSDS Coordinator
> : DuPont Fluoroproducts
Address : Wilmington, DE 19898
Telephone : (800) 441-7515
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
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