Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 1/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
1. Substance/preparation and company identification
Company 24 Hour Emergency Response Information
BASF Construction Chemicals CHEMTREC: 1-800-424-9300
100 Campus Drive BASF HOTLINE: 1-800-832-HELP
Florham Park, NJ 07932
2. Composition/information on ingredients
CAS Number Content (W/W) Chemical name
101-68-8 30.0 - 60.0 % Diphenylmethane-4,4'-diisocyanate (MDI)
9016-87-9 15.0 - 40.0 % P-MDI
7.0 - 13.0 % MDI Mixed Isomers
3. Hazard identification
Emergency overview
CAUTION: CONTAINS DIPHENYLMETHANE DIISOCYANATE (CAS No. 101-68-8). INHALATION OF MDI
MISTS OR VAPORS MAY CAUSE RESPIRATORY IRRITATION, BREATHLESSNESS, CHEST
DISCOMFORT AND REDUCED PULMONARY FUNCTION. OVEREXPOSURE WELL ABOVE THE PEL
MAY RESULT IN BRONCHITIS, BRONCHIAL SPASMS AND PULMONARY EDEMA. LONG-TERM
EXPOSURE TO ISOCYANATES HAS BEEN HAS BEEN REPORTED TO CAUSE LUNG DAMAGE,
INCLUDING REDUCED LUNG FUNCTION WHICH MAY BE PERMANENT. ACUTE OR CHRONIC
OVEREXPOSURE TO ISOCYANATES MAY CAUSE SENSITIZATION IN SOME INDIVIDUALS,
RESULTING IN ALLERGIC RESPIRATORY REACTIONS INCLUDING WHEEZING, SHORTNESS OF
BREATH AND DIFFICULTY BREATHING.
Potential health effects
Primary routes of exposure
Routes of entry for solids and liquids include eye and skin contact, ingestion and inhalation. Routes of entry for
gases include inhalation and eye contact. Skin contact may be a route of entry for liquified gases.
Acute toxicity:
Of moderate toxicity after short-term inhalation. Virtually nontoxic after a single ingestion. Virtually nontoxic
after a single skin contact.
Information on: MDI
Of moderate toxicity after short-term inhalation.
Virtually nontoxic after a single ingestion.
Virtually nontoxic after a single skin contact.
Irritation:
Eye contact causes irritation. Skin contact causes irritation.
Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 2/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
Information on: MDI
Irritating to eyes, respiratory system and skin.
Sensitization:
Sensitization after skin contact possible. The substance may cause sensitization of the respiratory tract.
Information on: MDI
The substance may cause sensitization of the respiratory tract.
Sensitization after skin contact possible.
Studies in animals suggest that dermal exposure may lead to pulmonary sensitization.
However, the relevance of this result for humans is unclear.
Repeated dose toxicity:
Information on: MDI
No other known chronic effects.
Medical conditions aggravated by overexposure:
The isocyanate component is a respiratory sensitizer. It may cause allergic reaction leading to asthma-like
spasms of the bronchial tubes and difficulty in breathing.
Persons with history of respiratory disease or hypersensitivity should not be exposed to this product.
An animal study indicated that MDI may induce respiratory hypersensitivity following dermal exposure.
Medical supervision of all employees who handle or come into contact with isocyanates is recommended.
Preemployment and periodic medical examinations with respiratory function tests (FEV, FVC as a minimum)
are suggested.
Persons with asthmatic conditions, chronic bronchitis, other chronic respiratory diseases, recurrent eczema or
pulmonary sensitization should be excluded from working with isocyanates. Once a person is diagnosed as
having pulmonary sensitization (allergic asthma) to isocyanates, further exposure is not recommended.
Contact may aggravate pulmonary disorders.
Potential environmental effects
Aquatic toxicity:
There is a high probability that the product is not acutely harmful to aquatic organisms.
4. First-Aid Measures
General advice:
Remove contaminated clothing.
If inhaled:
Remove the affected individual into fresh air and keep the person calm. Assist in breathing if necessary.
Immediate medical attention required.
If on skin:
Wash affected areas thoroughly with soap and water. If irritation develops, seek medical attention.
If in eyes:
In case of contact with the eyes, rinse immediately for at least 15 minutes with plenty of water. Immediate
medical attention required.
If swallowed:
Rinse mouth and then drink plenty of water. Do not induce vomiting. Never induce vomiting or give anything by
mouth if the victim is unconscious or having convulsions. Immediate medical attention required.
Note to physician
Hazards: Symptoms can appear later.
Antidote: Specific antidotes or neutralizers to isocyanates do not exist.
Treatment: Treatment should be supportive and based on the judgement of the physician in
response to the reaction of the patient.
5. Fire-Fighting Measures
Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 3/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
Flash point: 204.44 癈
Self-ignition temperature: not self-igniting
Suitable extinguishing media:
water, dry extinguishing media, carbon dioxide, foam
Hazards during fire-fighting:
nitrous gases, fumes/smoke, isocyanate, vapour
Protective equipment for fire-fighting:
Firefighters should be equipped with self-contained breathing apparatus and turn-out gear.
6. Accidental release measures
Personal precautions:
Clear area. Ensure adequate ventilation. Wear suitable personal protective clothing and equipment.
Environmental precautions:
Do not discharge into drains/surface waters/groundwater.
Cleanup:
Dike spillage.
For small amounts: Absorb isocyanate with suitable absorbent material (see ?40 CFR, sections 260, 264 and
265 for further information). Shovel into open container. Do not make container pressure tight. Move container
to a well-ventilated area (outside). Spill area can be decontaminated with the following recommended
decontamination solution: Mixture of 90 % water, 8 % concentrated ammonia, 2 % detergent. Add at a 10 to 1
ratio. Allow to stand for at least 48 hours to allow escape of evolved carbon dioxide.
For large amounts: If temporary control of isocyanate vapor is required, a blanket of protein foam or other
suitable foam (available from most fire departments) may be placed over the spill. Transfer as much liquid as
possible via pump or vacuum device into closed but not sealed containers for disposal.
For residues: The following measures should be taken for final cleanup: Wash down spill area with
decontamination solution. Allow solution to stand for at least 10 minutes.
7. Handling and Storage
Handling
General advice:
Mix thoroughly before use. If bulging of drum occurs, transfer to well ventilated area, puncture to relieve
pressure, open vent and let stand for 48 hours before resealing.
Protection against fire and explosion:
No explosion proofing necessary.
Storage
General advice:
Formation of CO2 and build up of pressure possible. Keep container tightly closed and in a well-ventilated
place. Outage of containers should be filled with dry inert gas at atmospheric pressure to avoid reaction with
moisture.
Storage incompatibility:
General: Segregate from bases.
Storage stability:
Storage temperature: 60 - 80 癋
Protect against moisture.
Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 4/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
8. Exposure controls and personal protection
Components with workplace control parameters
Diphenylmethane-4,4'-diisocya OSHA CLV 0.02 ppm 0.2 mg/m3 ;
nate (MDI) ACGIH TWA value 0.005 ppm ;
Advice on system design:
Provide local exhaust ventilation to maintain recommended P.E.L.
Personal protective equipment
Respiratory protection:
When workers are facing concentrations above the occupational exposure limits they must use appropriate
certified respirators. When atmospheric levels may exceed the occupational exposure limit (PEL or TLV)
NIOSH-certified air-purifying respirators equipped with an organic vapor sorbent and particulate filter can be
used as long as appropriate precautions and change out schedules are in place. Wear a NIOSH-certified (or
equivalent) TC19C positive pressure air supplied respirator. For emergency or non-routine, high exposure
situations, including confined space entry, use a NIOSH-certified full facepiece pressure demand
self-contained breathing apparatus (SCBA) or a full facepiece pressure demand supplied-air respirator (SAR)
with escape provisions.
Hand protection:
Chemical resistant protective gloves, Suitable materials, chloroprene rubber (Neoprene), nitrile rubber (Buna
N), chlorinated polyethylene, polyvinylchloride (Pylox), butyl rubber, fluoroelastomer (Viton)
Eye protection:
Tightly fitting safety goggles (chemical goggles). Wear face shield if splashing hazard exists.
Body protection:
Suitable materials, saran-coated material
General safety and hygiene measures:
Wear protective clothing as necessary to prevent contact. Eye wash fountains and safety showers must be
easily accessible. Observe the appropriate PEL value. Wash soiled clothing immediately. Contaminated
equipment or clothing should be cleaned after each use or disposed of.
9. Physical and Chemical Properties
Form: liquid
Odour: earthy, musty
Colour: colourless to slightly yellow
pH value: not applicable
Freezing point: Unspecified
Boiling point: 200 癈 ( 5 mmHg)
Vapour pressure: 0.00001 mmHg ( 20 癈)
Relative density: 1.2365
Bulk density: 10.1 lb/USg ( 25 癈)
Vapour density: Heavier than air.
Partitioning coefficient No data available.
n-octanol/water (log Pow):
Viscosity, dynamic: No data available.
% volatiles: primers and undercoaters
Solubility in other solvents: insoluble
10. Stability and Reactivity
Conditions to avoid:
Avoid moisture.
Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 5/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
Substances to avoid:
water, alcohols, strong bases, Substances/products that react with isocyanates.
Hazardous reactions:
The product is chemically stable.
Reacts with water, with formation of carbon dioxide. Risk of bursting. Reacts with alcohols. Reacts with acids.
Reacts with alkalies. Reacts with amines. Risk of exothermic reaction. Risk of violent reaction. Risk of
polymerization. Contact with certain rubbers and plastics can cause brittleness of the substance/product with
subsequent loss in strength.
Decomposition products:
Hazardous decomposition products: carbon monoxide, hydrogen cyanide, nitrogen oxides, aromatic
isocyanates, gases/vapours
Corrosion to metals:
No corrosive effect on metal.
Oxidizing properties:
Based on its structural properties the product is not classified as oxidizing.
11. Toxicological information
Carcinogenicity:
Information on: MDI
Indication of possible carcinogenic effect in animal tests.
However, the relevance of this result for humans is unclear.
----------------------------------
Developmental toxicity/teratogenicity:
Information on: MDI
The substance did not cause malformations in animal studies; however, toxicity to development was observed
at high doses that were toxic to the parental animals.
----------------------------------
12. Ecological Information
Information on: Diphenylmethane-4,4'-diisocyanate (MDI)
Acute and prolonged toxicity to fish:
OECD Guideline 203 static
zebra fish/LC0 (96 h): > 1,000 mg/l
----------------------------------
Information on: Diphenylmethane-4,4'-diisocyanate (MDI)
Acute toxicity to aquatic invertebrates:
OECD Guideline 202, part 1 static
Daphnia magna/EC50 (24 h): > 1,000 mg/l
----------------------------------
13. Disposal considerations
Waste disposal of substance:
Incinerate or dispose of in a licensed facility.
Do not discharge substance/product into sewer system.
Container disposal:
DRUMS:
Steel drums must be emptied and can be sent to a licensed drum reconditioner for reuse, a scrap metal dealer
or an approved landfill. Refer to 40 CFR ?261.7 (residues of hazardous waste in empty containers). Check
Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 6/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
with reconditioner to determine if decontamination is required. Decontaminate containers prior to disposal.
Recommend crushing, puncturing or other means to prevent unauthorized use of used containers.
14. Transport Information
Land transport
USDOT
Not classified as a dangerous good under transport regulations
Sea transport
IMDG
Not classified as a dangerous good under transport regulations
Air transport
IATA/ICAO
Not classified as a dangerous good under transport regulations
15. Regulatory Information
Federal Regulations
OSHA hazard category: Chronic target organ effects reported, ACGIH TLV established
SARA hazard categories (EPCRA 311/312): Acute, Chronic
SARA 313:
CAS Number Chemical name
101-68-8 Diphenylmethane-4,4'-diisocyanate (MDI)
9016-87-9 P-MDI
State regulations
State RTK
CAS Number Chemical name State RTK
101-68-8 Diphenylmethane-4,4'-diisocyanate (MDI) MA, NJ, PA
16. Other Information
HMIS III rating
Health: 2? Flammability: 1 Physical hazard: 1
HMIS uses a numbering scale ranging from 0 to 4 to indicate the degree of hazard. A value of zero means that the substance
possesses essentially no hazard; a rating of four indicates high hazard.
Local Contact Information
Safety data sheet
CONIPUR 78 PTB
Revision date : 2009/07/30 Page: 7/7
Version: 1.0 (30401027/SDS_GEN_US/EN)
BASF CORPORATION WILL NOT MAKE ITS PRODUCTS AVAILABLE TO CUSTOMERS FOR USE IN THE
MANUFACTURE OF MEDICAL DEVICES WHICH ARE INTENDED FOR PERMANENT IMPLANTATION IN
THE HUMAN BODY OR IN PERMANENT CONTACT WITH INTERNAL BODILY TISSUES OR FLUIDS.
END OF DATA SHEET
|