Right to Know
Hazardous Substance Fact Sheet
DIMETHYLCARBAMOYL CHLORIDE
Common Name:
Synonyms: DMCC; Chloroformic Acid Dimethylamide CAS Number: 79-44-7
Chemical Name: Carbamic Chloride, Dimethyl- RTK Substance Number: 0746
Date: December 1998 Revision: July 2008 DOT Number: UN 2262
Description and Use EMERGENCY RESPONDERS >>>> SEE PAGE 6
Hazard Summary
Dimethylcarbamoyl Chloride is a clear, colorless liquid with
an unpleasant odor. It is used as a chemical intermediate in Hazard Rating NJDHSS NFPA
making pesticides, pharmaceuticals and dyes. HEALTH 3 -
FLAMMABILITY 2 -
REACTIVITY 1 -
CARCINOGEN AND CORROSIVE
COMBUSTIBLE
POISONOUS GASES ARE PRODUCED IN FIRE
CONTAINERS MAY EXPLODE IN FIRE
DO NOT USE WATER
Reasons for Citation
Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; 3=serious;
Dimethylcarbamoyl Chloride is on the Right to Know
4=severe
Hazardous Substance List because it is cited by ACGIH,
DOT, NIOSH, NTP, DEP, IARC and EPA.
Dimethylcarbamoyl Chloride can affect you when inhaled
This chemical is on the Special Health Hazard Substance
and may be absorbed through the skin.
List.
Dimethylcarbamoyl Chloride should be handled as a
CARCINOGEN and MUTAGEN--WITH EXTREME
CAUTION.
Contact can irritate and burn the skin and eyes.
Inhaling Dimethylcarbamoyl Chloride can irritate the nose,
throat and lungs causing coughing, wheezing and/or
SEE GLOSSARY ON PAGE 5. shortness of breath.
Exposure to Dimethylcarbamoyl Chloride can cause
FIRST AID headache, nausea and vomiting.
Dimethylcarbamoyl Chloride may affect the liver.
Eye Contact
Immediately flush with large amounts of water for at least 30
minutes, lifting upper and lower lids. Remove contact
Workplace Exposure Limits
lenses, if worn, while flushing. Seek medical attention
immediately.
NIOSH: Recommends that exposure to occupational
Skin Contact carcinogens be limited to the lowest feasible
Quickly remove contaminated clothing. Immediately wash concentration.
contaminated skin with large amounts of soap and water.
Seek medical attention.
ACGIH: The threshold limit value (TLV) is 0.005 ppm
Inhalation averaged over an 8-hour workshift.
Remove the person from exposure.
Begin rescue breathing (using universal precautions) if
Dimethylcarbamoyl Chloride is a PROBABLE
breathing has stopped and CPR if heart action has stopped.
CARCINOGEN in humans. There may be no safe level of
Transfer promptly to a medical facility.
exposure to a carcinogen, so all contact should be reduced
to the lowest possible level.
The above exposure limits are for air levels only. When skin
EMERGENCY NUMBERS contact also occurs, you may be overexposed, even though
Poison Control: 1-800-222-1222 air levels are less than the limits listed above.
CHEMTREC: 1-800-424-9300
NJDEP Hotline: 1-877-927-6337
National Response Center: 1-800-424-8802
Page 2 of 6
DIMETHYLCARBAMOYL CHLORIDE
Determining Your Exposure Reproductive Hazard
According to the information presently available to the New
Read the product manufacturer's Material Safety Data Jersey Department of Health and Senior Services,
Sheet (MSDS) and the label to determine product Dimethylcarbamoyl Chloride has not been tested for its
ability to affect reproduction.
ingredients and important safety and health information
about the product mixture.
Other Effects
For each individual hazardous ingredient, read the New
Dimethylcarbamoyl Chloride can irritate the lungs.
Jersey Department of Health and Senior Services Repeated exposure may cause bronchitis to develop with
Hazardous Substance Fact Sheet, available on the RTK coughing, phlegm, and/or shortness of breath.
Program website (www.nj.gov/health/eoh/rtkweb) or in Dimethylcarbamoyl Chloride may affect the liver.
your facility's RTK Central File or Hazard Communication
Standard file.
Medical
You have a right to this information under the New Jersey
Worker and Community Right to Know Act, the Public Medical Testing
Employees Occupational Safety and Health (PEOSH) Act If symptoms develop or overexposure is suspected, the
if you are a public worker in New Jersey, and under the following are recommended:
federal Occupational Safety and Health Act (OSHA) if you
Lung function tests
are a private worker.
Liver function tests
The New Jersey Right to Know Act requires most
employers to label chemicals in the workplace and Any evaluation should include a careful history of past and
present symptoms with an exam. Medical tests that look for
requires public employers to provide their employees with
damage already done are not a substitute for controlling
information concerning chemical hazards and controls.
exposure.
The federal OSHA Hazard Communication Standard (29
CFR 1910.1200) and the PEOSH Hazard Communication
Request copies of your medical testing. You have a legal right
Standard (N.J.A.C. 12:100-7) require employers to provide to this information under the OSHA Access to Employee
similar information and training to their employees. Exposure and Medical Records Standard (29 CFR 1910.1020).
This Fact Sheet is a summary of available information Mixed Exposures
regarding the health hazards that may result from exposure. Smoking can cause heart disease, lung cancer,
Duration of exposure, concentration of the substance and other emphysema, and other respiratory problems. It may worsen
factors will affect your susceptibility to any of the potential respiratory conditions caused by chemical exposure. Even if
effects described below. you have smoked for a long time, stopping now will reduce
your risk of developing health problems.
More than light alcohol consumption can cause liver
Health Hazard Information damage. Drinking alcohol may increase the liver damage
caused by Dimethylcarbamoyl Chloride.
Acute Health Effects
The following acute (short-term) health effects may occur
immediately or shortly after exposure to Dimethylcarbamoyl
Chloride:
Contact can irritate and burn the skin and eyes.
Inhaling Dimethylcarbamoyl Chloride can irritate the nose,
throat and lungs causing coughing, wheezing and/or
shortness of breath.
Exposure to Dimethylcarbamoyl Chloride can cause
headache, nausea and vomiting.
Chronic Health Effects
The following chronic (long-term) health effects can occur at
some time after exposure to Dimethylcarbamoyl Chloride
and can last for months or years:
Cancer Hazard
Dimethylcarbamoyl Chloride is a PROBABLE
CARCINOGEN in humans since it has been shown to cause
nose and skin cancer in animals.
Many scientists believe there is no safe level of exposure to
a carcinogen. Such substance may also have the potential
for causing reproductive damage in humans.
Page 3 of 6
DIMETHYLCARBAMOYL CHLORIDE
Workplace Controls and Practices Eye Protection
Wear indirect-vent, impact and splash resistant goggles
Very toxic chemicals, or those that are reproductive hazards or
when working with liquids.
sensitizers, require expert advice on control measures if a less
Wear a face shield along with goggles when working with
toxic chemical cannot be substituted. Control measures
corrosive, highly irritating or toxic substances.
include: (1) enclosing chemical processes for severely
Do not wear contact lenses when working with this
irritating and corrosive chemicals, (2) using local exhaust
substance.
ventilation for chemicals that may be harmful with a single
exposure, and (3) using general ventilation to control
Respiratory Protection
exposures to skin and eye irritants. For further information on
Improper use of respirators is dangerous. Respirators
workplace controls, consult the NIOSH document on Control
Banding at www.cdc.gov/niosh/topics/ctrlbanding/. should only be used if the employer has implemented a written
program that takes into account workplace conditions,
The following work practices are also recommended: requirements for worker training, respirator fit testing, and
medical exams, as described in the OSHA Respiratory
Label process containers.
Protection Standard (29 CFR 1910.134).
Provide employees with hazard information and training.
Monitor airborne chemical concentrations.
Where the potential exists for exposure over 0.005 ppm, use
Use engineering controls if concentrations exceed
a NIOSH approved supplied-air respirator with a full
recommended exposure levels.
facepiece operated in a pressure-demand or other positive-
Provide eye wash fountains and emergency showers.
pressure mode. For increased protection use in combination
Wash or shower if skin comes in contact with a hazardous
with an auxiliary self-contained breathing apparatus
material.
operated in a pressure-demand or other positive-pressure
Always wash at the end of the workshift.
mode.
Change into clean clothing if clothing becomes
contaminated.
Do not take contaminated clothing home.
Get special training to wash contaminated clothing.
Fire Hazards
Do not eat, smoke, or drink in areas where chemicals are
If employees are expected to fight fires, they must be trained
being handled, processed or stored.
Wash hands carefully before eating, smoking, drinking, and equipped as stated in the OSHA Fire Brigades Standard
applying cosmetics or using the toilet. (29 CFR 1910.156).
Dimethylcarbamoyl Chloride is a COMBUSTIBLE LIQUID.
Personal Protective Equipment Use dry chemical, CO2, alcohol-resistant foam or other foam
extinguishing agents.
The OSHA Personal Protective Equipment Standard (29 CFR DO NOT USE WATER.
1910.132) requires employers to determine the appropriate POISONOUS GASES ARE PRODUCED IN FIRE, including
Hydrogen Chloride and Nitrogen Oxides.
personal protective equipment for each hazard and to train
CONTAINERS MAY EXPLODE IN FIRE.
employees on how and when to use protective equipment.
Use water spray only to keep fire-exposed containers cool
as water will decompose Dimethylcarbamoyl Chloride to
The following recommendations are only guidelines and may form toxic Hydrogen Chloride and Dimethylamine.
not apply to every situation.
Gloves and Clothing
Avoid skin contact with Dimethylcarbamoyl Chloride.
Wear personal protective equipment made from material that
can not be permeated or degraded by this substance.
Safety equipment suppliers and manufacturers can provide
recommendations on the most protective glove and clothing
material for your operation.
Safety equipment manufacturers recommend Silver
Shield?4H?for gloves and DuPont Tychem?CSM,
Responder? and TK, or the equivalent, as protective
materials for known carcinogens.
All protective clothing (suits, gloves, footwear, headgear)
should be clean, available each day, and put on before work.
Page 4 of 6
DIMETHYLCARBAMOYL CHLORIDE
Spills and Emergencies Occupational Health Information
If employees are required to clean-up spills, they must be
Resources
properly trained and equipped. The OSHA Hazardous Waste
The New Jersey Department of Health and Senior Services,
Operations and Emergency Response Standard (29 CFR
Occupational Health Service, offers multiple services in
1910.120) may apply.
occupational health. These services include providing
informational resources, educational materials, public
If Dimethylcarbamoyl Chloride is spilled or leaked, take the
presentations, and industrial hygiene and medical
following steps:
investigations and evaluations.
Evacuate personnel and secure and control entrance to the
area.
Eliminate all ignition sources.
For more information, please contact:
Absorb liquids in vermiculite, dry sand, earth, or a similar
material and deposit in sealed containers.
New Jersey Department of Health & Senior Services
DO NOT USE WATER OR WET METHOD.
Right to Know Program
Ventilate area after clean-up is complete.
DO NOT wash into sewer. PO Box 368
It may be necessary to contain and dispose of Trenton, NJ 08625-0368
Dimethylcarbamoyl Chloride as a HAZARDOUS WASTE. Phone: 609-984-2202
Contact your state Department of Environmental Protection
Fax: 609-984-7407
(DEP) or your regional office of the federal Environmental
E-mail: rtk@doh.state.nj.us
Protection Agency (EPA) for specific recommendations.
Web address: http://www.nj.gov/health/eoh/rtkweb
Handling and Storage The Right to Know Hazardous Substance Fact Sheets
are not intended to be copied and sold
Prior to working with Dimethylcarbamoyl Chloride you should
for commercial purposes.
be trained on its proper handling and storage.
Dimethylcarbamoyl Chloride will react with WATER,
STEAM and MOISTURE to produce toxic Hydrogen Chloride
and Dimethylamine.
Dimethylcarbamoyl Chloride reacts vigorously or
explosively if mixed with DIISOPROPYL ETHER or other
ETHERS in the presence of small amounts of METAL
SALTS.
Dimethylcarbamoyl Chloride is not compatible with
OXIDIZING AGENTS (such as PERCHLORATES,
PEROXIDES, PERMANGANATES, CHLORATES,
NITRATES, CHLORINE, BROMINE and FLUORINE);
ALCOHOLS; STRONG BASES (such as SODIUM
HYDROXIDE and POTASSIUM HYDROXIDE); and
AMINES.
Store in tightly closed containers in a cool, well-ventilated
area away from METALS (such as STEEL and
GALVANIZED STEEL/ZINC) as flammable and explosive
Hydrogen gas may form.
Sources of ignition, such as smoking and open flames, are
prohibited where Dimethylcarbamoyl Chloride is used,
handled, or stored in a manner that could create a potential
fire or explosion hazard.
Use only non-sparking tools and equipment, especially when
opening and closing containers of Dimethylcarbamoyl
Chloride.
Page 5 of 6
DIMETHYLCARBAMOYL CHLORIDE
GLOSSARY
ACGIH is the American Conference of Governmental Industrial LEL or Lower Explosive Limit, is the lowest concentration of
Hygienists. They publish guidelines called Threshold Limit a combustible substance (gas or vapor) in the air capable of
Values (TLVs) for exposure to workplace chemicals. continuing an explosion.
Acute Exposure Guideline Levels (AEGLs) are established mg/m3 means milligrams of a chemical in a cubic meter of air.
by the EPA. They describe the risk to humans resulting from It is a measure of concentration (weight/volume).
once-in-a lifetime, or rare, exposure to airborne chemicals.
A mutagen is a substance that causes mutations. A mutation
Boiling point is the temperature at which a substance can is a change in the genetic material in a body cell. Mutations
change its physical state from a liquid to a gas. can lead to birth defects, miscarriages, or cancer.
A carcinogen is a substance that causes cancer. NFPA is the National Fire Protection Association. It classifies
substances according to their fire and explosion hazard.
The CAS number is unique, identifying number, assigned by
the Chemical Abstracts Service, to a specific chemical. NIOSH is the National Institute for Occupational Safety and
Health. It tests equipment, evaluates and approves
CFR is the Code of Federal Regulations, which are the respirators, conducts studies of workplace hazards, and
regulations of the United States government. proposes standards to OSHA.
A combustible substance is a solid, liquid or gas that will burn. NTP is the National Toxicology Program which tests chemicals
and reviews evidence for cancer.
A corrosive substance is a gas, liquid or solid that causes
destruction of human skin or severe corrosion of containers. OSHA is the federal Occupational Safety and Health
Administration, which adopts and enforces health and safety
DEP is the New Jersey Department of Environmental standards.
Protection.
PEOSHA is the New Jersey Public Employees Occupational
DOT is the Department of Transportation, the federal agency Safety and Health Act, which adopts and enforces health and
that regulates the transportation of chemicals. safety standards in public workplaces.
EPA is the Environmental Protection Agency, the federal Permeated is the movement of chemicals through protective
agency responsible for regulating environmental hazards. materials.
ERG is the Emergency Response Guidebook. It is a guide for PIH is a DOT designation for chemicals which are Poison
emergency responders for transportation emergencies Inhalation Hazards.
involving hazardous substances.
ppm means parts of a substance per million parts of air. It is a
Emergency Response Planning Guideline (ERPG) values measure of concentration by volume in air.
are intended to provide estimates of concentration ranges
where one reasonably might anticipate observing adverse A reactive substance is a solid, liquid or gas that releases
effects. energy under certain conditions.
A fetus is an unborn human or animal. STEL is a Short Term Exposure Limit which is usually a 15-
minute exposure that should not be exceeded at any time
A flammable substance is a solid, liquid, vapor or gas that will during a work day.
ignite easily and burn rapidly.
A teratogen is a substance that causes birth defects by
The flash point is the temperature at which a liquid or solid damaging the fetus.
gives off vapor that can form a flammable mixture with air.
UEL or Upper Explosive Limit is the highest concentration in
IARC is the International Agency for Research on Cancer, a air above which there is too much fuel (gas or vapor) to begin a
scientific group. reaction or explosion.
Ionization Potential is the amount of energy needed to Vapor Density is the ratio of the weight of a given volume of
remove an electron from an atom or molecule. It is measured one gas to the weight of another (usually Hydrogen), at the
in electron volts. same temperature and pressure.
IRIS is the Integrated Risk Information System database The vapor pressure is a measure of how readily a liquid or a
maintained by federal EPA. The database contains solid mixes with air at its surface. A higher vapor pressure
information on human health effects that may result from indicates a higher concentration of the substance in air and
exposure to various chemicals in the environment. therefore increases the likelihood of breathing it in.
INFORMATION FOR EMERGENCY RESPONDERS Page 6 of 6
Common Name: DIMETHYLCARBAMOYL CHLORIDE
Synonyms: DMCC; Chloroformic Acid Dimethylamide
CAS No: 79-44-7
Molecular Formula: C3H6ClNO
RTK Substance No: 0746
Description: Clear, colorless liquid with an unpleasant odor
HAZARD DATA
Hazard Rating Firefighting Reactivity
Dimethylcarbamoyl Chloride is a COMBUSTIBLE Dimethylcarbamoyl Chloride will react with
3 - Health
LIQUID. WATER, STEAM and MOISTURE to produce toxic
2 - Fire Hydrogen Chloride and Dimethylamine.
Use dry chemical, CO2, alcohol-resistant foam or other
Dimethylcarbamoyl Chloride reacts vigorously or
foam extinguishing agents.
1 - Reactivity
explosively if mixed with DIISOPROPYL ETHER or
DO NOT USE WATER.
DOT#: UN 2262 other ETHERS in the presence of small amounts of
POISONOUS GASES ARE PRODUCED IN FIRE,
METAL SALTS.
ERG Guide #: 156 including Hydrogen Chloride and Nitrogen Oxides.
Dimethylcarbamoyl Chloride is not compatible with
CONTAINERS MAY EXPLODE IN FIRE.
Hazard Class: 8 OXIDIZING AGENTS (such as PERCHLORATES,
Use water spray only to keep fire-exposed containers
(Corrosive) PEROXIDES, PERMANGANATES, CHLORATES,
cool as water will decompose Dimethylcarbamoyl NITRATES, CHLORINE, BROMINE and
Chloride to form toxic Hydrogen Chloride and FLUORINE); ALCOHOLS; STRONG BASES (such
Dimethylamine. as SODIUM HYDROXIDE and POTASSIUM
HYDROXIDE); and AMINES.
SPILL/LEAKS PHYSICAL PROPERTIES
Odor Threshold: Unpleasant odor
Isolation Distance:
o o
Flash Point: 155 F (68 C)
Small Spill: 60 meters (200 feet)
Vapor Density: 3.7 (air = 1)
Large Spill: 270 meters (900 feet) o o
Vapor Pressure: 2.5 mm Hg at 77 F (25 C)
Fire: 800 meters (1/2 mile) Specific Gravity: 1.2 (water = 1)
Water Solubility: Reactive/Decomposes
Absorb liquids in vermiculite, dry sand, earth, or a
similar material and deposit in sealed containers. o o o o
Boiling Point: 329 to 333 F (165 to 167 C)
DO NOT USE WATER OR WET METHOD. o o
Melting Point: -27 F (-33 C)
DO NOT wash into sewer. Molecular Weight: 107.6
EXPOSURE LIMITS PROTECTIVE EQUIPMENT
Gloves: Silver Shield?4H?br>
OSHA: None
Coveralls: DuPont Tychem?CSM, Responder? and TK (for known
NIOSH: Lowest feasible concentration carcinogens)
ACGIH: 0.005 ppm, 8-hr TWA Respirator: >0.005 ppm - Supplied air
IDLH: None
HEALTH EFFECTS FIRST AID AND DECONTAMINATION
Eyes: Remove the person from exposure.
Irritation and burns
Flush eyes with large amounts of water for at least 30 minutes. Remove
Skin: Irritation and burns
contact lenses if worn. Seek medical attention immediately.
Inhalation: Nose, throat and lung irritation with
Quickly remove contaminated clothing and wash contaminated skin with
coughing, wheezing and shortness of
large amounts of soap and water. Seek medical attention.
breath
Begin artificial respiration if breathing has stopped and CPR if necessary.
Headache, nausea and vomiting
Transfer promptly to a medical facility.
Chronic: Cancer (nose and skin) in animals
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