SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 09/AUG/2005
Date Updated: 11/JUL/2005
Version 1.5
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name HYDROFLUORIC ACID 40 %
Product Number 01067
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
HYDROFLUORIC ACID, NOT MORE THAN 7664-39-3 231-634-8 009-003-00-1
60% PERCENT STRENGTH
Formula HF
Molecular Weight 20.01 AMU
Synonyms Acide fluorhydrique (French) * Acido fluoridrico
(Italian) * Fluorowodor (Polish) *
Fluorwasserstoff (German) * Fluorwaterstof
(Dutch) * Hydrofluoride * Hydrogen fluoride
(ACGIH:OSHA) * RCRA waste number U134 * Rubigine
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Very toxic by inhalation, in contact with skin and if swallowed.
Causes severe burns.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately. Do not induce vomiting.
GENERAL INFORMATION
Hydrofluoric (HF) acid burns require immediate and specialized
first aid and medical treatment. Symptoms may be delayed up to
24 hours depending on the concentration of HF. After
decontamination with water, further damage can occur due to
penetration/absorption of the fluoride ion. Treatment should be
directed toward binding the fluoride ion as well as the effects
of exposure. Skin exposures can be treated with a 2.5% calcium
gluconate gel repeated until burning ceases. More serious skin
exposures may require subcutaneous calcium gluconate except for
digital areas unless the physician is experienced in this
technique, due to the potential for tissue injury from increased
pressure. Absorption can readily occur through the subungual
areas and should be considered when undergoing decontamination.
Prevention of absorption of the fluoride ion in cases of
ingestion can be obtained by giving milk, chewable calcium
carbonate tablets or Milk of Magnesia to conscious victims.
Conditions such as hypocalcemia, hypomagnesemia and cardiac
arrhythmias should be monitored for, since they can occur after
exposure.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Dry chemical powder.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
Explosion Hazards: Container explosion may occur under fire
conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed
container, and hold for waste disposal. Ventilate area and wash
spill site after material pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store away from
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heat. Store in a cool dry place.
Unsuitable: Do not store in glass
Incompatible Materials: Glass
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 0.5 MG/M3
Poland NDSCh 2 MG/M3
Poland NDSP -
EXPOSURE LIMITS - EUROPEAN UNION
Source Type Value
OEL OEL 1.5 mg/m3
1.8 ppm
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 1.6 mg/m3
2 ppm
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 2.5 mg/m3
3 ppm
Remarks: =1=
Remarks: H
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 0.6 mg/m3
0.8 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
CLV (Ceili1.7 mg/m3
2 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 1.5 mg/m3
1.8 ppm
Remarks: M
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL STEL 2.5 mg/m3
3 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
Special Protective Measures: Faceshield (8-inch minimum).
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9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 25 mmHg 20 藲C
SG/Density 1.16 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 1.27 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Light.
Materials to Avoid: Avoid contact with metals., Alkali metals,
Strong bases, Glass
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Hydrogen fluoride.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: MW7875000
ACUTE TOXICITY
LCLO
Inhalation
Human
50 ppm
30M
LC50
Inhalation
Rat
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1,276 ppm
1H
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Lacrimation. Behavioral:Change in motor activity
(specific assay). Gastrointestinal:Changes in structure or
function of salivary glands.
LC50
Inhalation
Mouse
342 ppm
1H
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Corneal damage. Sense Organs and Special Senses
(Nose, Eye, Ear, and Taste):Eye:Other. Lungs, Thorax, or
Respiration:Dyspnea.
LC50
Inhalation
Monkey
1,774 ppm
1H
Remarks: Behavioral:Coma. Lungs, Thorax, or
Respiration:Cyanosis. Gastrointestinal:Other changes.
LC50
Inhalation
Guinea pig
4,327 ppm
15M
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Lacrimation. Lungs, Thorax, or
Respiration:Respiratory depression. Nutritional and Gross
Metabolic:Weight loss or decreased weight gain.
IRRITATION DATA
Eyes
Human
50 mg
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting.
ROUTE OF EXPOSURE
Skin Contact: Causes severe burns.
Skin Absorption: May be fatal if absorbed through skin.
Eye Contact: Material is extremely destructive to the tissue of
the eyes. Causes severe burns.
Inhalation: May be fatal if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract.
Ingestion: May be fatal if swallowed.
TARGET ORGAN INFORMATION
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Kidneys. Liver. Central nervous system.
CHRONIC EXPOSURE - MUTAGEN
Result: Laboratory experiments have shown mutagenic effects.
Rat
1 MG/M3/6H/24D-I
Inhalation
Cytogenetic analysis
CHRONIC EXPOSURE - TERATOGEN
Result: Laboratory experiments have shown teratogenic effects.
Species: Rat
Dose: 4980 UG/M3/4H
Route of Application: Inhalation
Exposure Time: (1-22D PREG)
Result: Effects on Embryo or Fetus: Fetal death.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 470 UG/M3/4H
Route of Application: Inhalation
Exposure Time: (1-22D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Fertility:
Post-implantation mortality (e.g., dead and/or resorbed implants
per total number of implants).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1790
Class: 8
PG: II
Proper Shipping Name: Hydrofluoric acid
IMDG
UN#: 1790
Class: 8
PG: II
Subrisk: 6.1
Proper Shipping Name: Hydrofluoric acid
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
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UN#: 1790
Class: 8
PG: II
Subrisk: 6.1
Proper Shipping Name: Hydrofluoric acid
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 009-003-00-1
NOTA: B
INDICATION OF DANGER: T+ C
Very toxic. Corrosive.
R-PHRASES: 26/27/28 35
Very toxic by inhalation, in contact with skin and if
swallowed. Causes severe burns.
S-PHRASES: 26 28 36/37/39 45
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. After contact with skin, wash
immediately with plenty of water. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 1
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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