SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 09/AUG/2005
Date Updated: 13/MAR/2004
Version 1.1
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name HYDRAZINE MONOHYDROCHLORIDE, 97%
Product Number 216194
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
HYDRAZINE MONOHYDROCHLORIDE 2644-70-4 220-154-4 None
Formula H2NNH2.HCl
Molecular Weight 68.51 AMU
Synonyms Hydrazine monochloride * Hydrazinium chloride *
Hydrazinium monochloride
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Causes burns. Toxic if swallowed. May cause sensitization by skin
contact. Limited evidence of a carcinogenic effect.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Under fire conditions, material may decompose to form flammable
and/or explosive mixtures in air.
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
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MP/MP Range 89 藲C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Materials to Avoid: Oxidizing agents, Bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nitrogen oxides, Hydrogen
chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: MV4625000
ACUTE TOXICITY
LD50
Oral
Rat
128 mg/kg
Remarks: Behavioral:Convulsions or effect on seizure threshold.
LD50
Intraperitoneal
Rat
126 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
LD50
Intravenous
Rat
118 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
LD50
Oral
Mouse
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126 mg/kg
Remarks: Behavioral:Convulsions or effect on seizure threshold.
LD50
Intraperitoneal
Mouse
133 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
LD50
Intravenous
Mouse
122 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
LD50
Intravenous
Dog
53 MG/KG
Remarks: Behavioral:Convulsions or effect on seizure threshold.
SENSITIZATION
Sensitization: May cause allergic reaction.
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. Can cause CNS depression. May cause convulsions.
Exposure can cause: Damage to the liver. Damage to the kidneys.
Damage to the lungs.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be toxic in contact with skin.
Eye Contact: Causes burns.
Inhalation: May be toxic by inhalation. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Damage to the liver. Damage to the kidneys. Damage to the lungs.
Nerves. Blood.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be possibly carcinogenic based on its IARC, ACGIH,
NTP, or EPA classification.
CHRONIC EXPOSURE - MUTAGEN
Mouse
200 MG/KG
Intraperitoneal
96H
Micronucleus test
Mouse
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80 MG/KG
Intraperitoneal
specific locus test
Hamster
500 UMOL/L
Cell Type: lung
Sister chromatid exchange
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2923
Class: 8
PG: II
Proper Shipping Name: Corrosive solid, toxic, n.o.s.
IMDG
UN#: 2923
Class: 8
PG: II
Subrisk: 6.1
Proper Shipping Name: Corrosive solid, toxic, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 2923
Class: 8
PG: II
Subrisk: 6.1
Proper Shipping Name: Corrosive solid, toxic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: T
Toxic.
R-PHRASES: 34 25 43 40
Causes burns. Toxic if swallowed. May cause sensitization by
skin contact. Limited evidence of a carcinogenic effect.
S-PHRASES: 45 26 28 27 36
In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible). In case of contact
with eyes, rinse immediately with plenty of water and seek
medical advice. After contact with skin, wash immediately with
ALDRICH - 216194 www.sigma-aldrich.com Page 5
plenty of water. Take off immediately all contaminated
clothing. Wear suitable protective clothing.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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