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MSDS Material Safety Data Sheet
CAS

461-72-3

File Name: 461-72-3.asp

                              SIGMA-ALDRICH

Material Safety Data Sheet

Date Printed: 09/AUG/2005
Date Updated: 13/MAR/2004
Version 1.1
According to 91/155/EEC


1 - Product and Company Information

Product Name HYDANTOIN, 99%
Product Number 156361

Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)

2 - Composition/Information on Ingredients

Product Name CAS # EC no Annex I
Index Number
HYDANTOIN 461-72-3 207-313-3 None

Formula C3H4N2O2
Molecular Weight 100.08 AMU
Synonyms Glycolylurea * 2,4-Imidazolidinedione (9CI) *
2-Imidazolin-4(or 5)-one, 2-hydroxy-

3 - Hazards Identification



4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

5 - Fire Fighting Measures

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear protective equipment.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.

7 - Handling and Storage


8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Mechanical exhaust.

PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.

9 - Physical and Chemical Properties

Appearance Color: Faintly yellow
Form: Powder

Property Value At Temperature or Pressure

pH N/A
BP/BP Range N/A
MP/MP Range 220 藲C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A


ALDRICH - 156361 www.sigma-aldrich.com Page 2
10 - Stability and Reactivity

STABILITY
Stable: Stable.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

RTECS NUMBER: MT8210000

ROUTE OF EXPOSURE
Multiple Routes: May be harmful by inhalation, ingestion, or
skin absorption. May cause irritation.

CONDITIONS AGGRAVATED BY EXPOSURE
The toxicological properties have not been thoroughly
investigated.

CHRONIC EXPOSURE - TERATOGEN

Species: Woman
Dose: 4140 MG/KG
Route of Application: Oral
Exposure Time: (1-39W PREG)
Result: Specific Developmental Abnormalities: Urogenital system.

Species: Mouse
Dose: 12 GM/KG
Route of Application: Intraperitoneal
Exposure Time: (11-13D PREG)
Result: Effects on Embryo or Fetus: Fetal death. Specific
Developmental Abnormalities: Craniofacial (including nose and
tongue). Specific Developmental Abnormalities: Cardiovascular
(circulatory) system.

Species: Mouse
Dose: 9 GM/KG
Route of Application: Intraperitoneal
Exposure Time: (8-10D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system. Specific Developmental Abnormalities: Musculoskeletal
system.

Species: Mouse
Dose: 12 GM/KG
Route of Application: Intraperitoneal
Exposure Time: (8-10D PREG)
Result: Specific Developmental Abnormalities: Eye, ear.

Species: Mouse
Dose: 6 GM/KG
Route of Application: Intraperitoneal
Exposure Time: (8-10D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).


ALDRICH - 156361 www.sigma-aldrich.com Page 3
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD

Species: Rat
Dose: 14400 MG/KG
Route of Application: Oral
Exposure Time: (7-18D PREG)
Result: Effects on Newborn: Live birth index (# fetuses per
litter; measured after birth). Effects on Newborn: Other
neonatal measures or effects.

12 - Ecological Information

No data available.

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.

14 - Transport Information

RID/ADR
Non-hazardous for road transport.

IMDG
Non-hazardous for sea transport.

IATA
Non-hazardous for air transport.

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
S-PHRASES: 22 24/25
Do not breathe dust. Avoid contact with skin and eyes.

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.

DISCLAIMER
For R&D use only. Not for drug, household or other uses.




ALDRICH - 156361 www.sigma-aldrich.com Page 4

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