SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 21/FEB/2005
Date Updated: 13/MAR/2004
Version 1.6
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name CARBON DISULFIDE, ANHYDROUS, >=99%
Product Number 335266
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
CARBON DISULFIDE 75-15-0 200-843-6 006-003-00-3
Formula CS2
Molecular Weight 76.14 AMU
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Irritating to eyes and skin. Toxic: danger of
serious damage to health by prolonged exposure through inhalation.
Possible risk of impaired fertility. Possible risk of harm to the
unborn child.
Repr. Cat.3
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions. Forms explosive mixtures in air. May
explode when heated.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep container closed. Keep away from
heat, sparks, and open flame.
Incompatible Materials: Caution: contact with azides or active
metals such as sodium, potassium, zinc, etc., May cause fires
and explosions.
SPECIAL REQUIREMENTS: May develop pressure. Refrigerate before
opening.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
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EXPOSURE LIMITS
Country Source Type Value
Poland NDS 18 MG/M3
Poland NDSCh 30 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 15 mg/m3
5 ppm
Remarks: H
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 30 mg/m3
10 ppm
Remarks: 4
Remarks: H
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 15 mg/m3
5 ppm
Remarks: H
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level16 mg/m3
5 ppm
Remarks: H, R
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 15mg/m3* 5ppm*
Remarks: H B M
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 32 mg/m3
10 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Color: Colorless
Odor: Stench.
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 46 掳C
MP/MP Range -112 - -111 掳C
Flash Point -30 掳C Method: closed cup
Flammability N/A
Autoignition Temp 100 掳C
Oxidizing Properties N/A
Explosive Properties N/A
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Explosion Limits Lower: 1.3 %
Upper: 50 %
Vapor Pressure 296.241 mmHg 20 掳C
SG/Density 1.26 g/cm3
Partition Coefficient Log Kow: 2.16
Viscosity N/A
Vapor Density 2.67 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Alkali metals, Zinc, Amines, Azides, Oxidizing
agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Sulfur oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
ACUTE TOXICITY
LCLO
Inhalation
Human
4,000 ppm
30M
LCLO
Inhalation
Human
2,000 ppm
5M
LD50
Oral
Rat
1200 mg/kg
LC50
Inhalation
Rat
25,000 mg/m3
2H
LD50
Oral
Mouse
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2780 mg/kg
LC50
Inhalation
Mouse
10,000 mg/m3
2H
LD50
Oral
Rabbit
2550 mg/kg
LD50
Oral
Guinea pig
2125 mg/kg
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Damage to the kidneys. Damage to the liver.
Damage to the heart. May cause convulsions.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Readily absorbed through skin. May be harmful
if absorbed through the skin. May be harmful if absorbed through
the skin.
Eye Contact: Causes eye irritation.
Inhalation: Toxic if inhaled. Material may be irritating to
mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Eyes. Nerves. Liver. Kidneys. Heart. Cardiovascular system. Male
reproductive system. Female reproductive system.
CONDITIONS AGGRAVATED BY EXPOSURE
May cause nervous system disturbances.
CHRONIC EXPOSURE - MUTAGEN
Result: Laboratory experiments have shown mutagenic effects.
Human
8 MG/L
Cell Type: lymphocyte
Sister chromatid exchange
Human
10200 UG/L
Cell Type: lymphocyte
Sister chromatid exchange
CHRONIC EXPOSURE - TERATOGEN
Result: Possible risk of congenital malformation in the fetus.
Species: Rat
Dose: 2 GM/KG
Route of Application: Oral
Exposure Time: (6-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
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Species: Rat
Dose: 10 MG/M3/8H
Route of Application: Inhalation
Exposure Time: (1-22D PREG)
Result: Specific Developmental Abnormalities: Eye, ear. Effects
on Newborn: Viability index (e.g., # alive at day 4 per # born
alive).
Species: Rat
Dose: 100 MG/M3/8H
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Effects on Embryo or Fetus: Fetal death. Specific
Developmental Abnormalities: Craniofacial (including nose and
tongue). Specific Developmental Abnormalities: Homeostasis
Species: Rabbit
Dose: 2100 MG/KG
Route of Application: Oral
Exposure Time: (6-19D PREG)
Result: Specific Developmental Abnormalities: Other
developmental abnormalities.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: May cause reproductive disorders.
Species: Man
Dose: 40 MG/M3
Route of Application: Inhalation
Exposure Time: (91W MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Rat
Dose: 200 MG/M3/24H
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea).
Species: Rat
Dose: 100 MG/M3/8H
Route of Application: Inhalation
Exposure Time: (1-22D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
Species: Rat
Dose: 30 UG/M3/8H
Route of Application: Inhalation
Exposure Time: (1-22D PREG)
Result: Effects on Newborn: Behavioral.
Species: Rat
Dose: 600 PPM/6H
Route of Application: Inhalation
Exposure Time: (50D MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count). Paternal
Effects: Prostate, seminal vessicle, Cowper's gland, accessory
glands.
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Species: Mouse
Dose: 2000 MG/M3/2H
Route of Application: Inhalation
Exposure Time: (1-21D PREG)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Fertility: Litter size
(e.g.; # fetuses per litter; measured before birth).
Species: Rabbit
Dose: 350 MG/KG
Route of Application: Oral
Exposure Time: (6-19D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
12 - Ecological Information
No data available.
ECOTOXICOLOGICAL EFFECTS
Test Type: LC50 Fish
Species: other fish
Time: 96 h
Value: 162 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1131
Class: 3
PG: I
Proper Shipping Name: Carbon disulphide
IMDG
UN#: 1131
Class: 3
PG: I
Subrisk: 6.1
Proper Shipping Name: Carbon disulphide
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1131
Class: 3
PG: I
Subrisk: 6.1
Proper Shipping Name: Carbon disulphide
Inhalation Packing Group I: No
15 - Regulatory Information
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CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 006-003-00-3
INDICATION OF DANGER: F T
Highly Flammable. Toxic.
R-PHRASES: 11 36/38 48/23 62 63
Highly flammable. Irritating to eyes and skin. Toxic: danger of
serious damage to health by prolonged exposure through
inhalation. Possible risk of impaired fertility. Possible risk
of harm to the unborn child.
S-PHRASES: 16 33 36/37 45
Keep away from sources of ignition - no smoking. Take
precautionary measures against static discharges. Wear suitable
protective clothing and gloves. In case of accident or if you
feel unwell, seek medical advice immediately (show the label
where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 1
NORWAY
Labelling for organic solvents where the package is 1liter or
more.
YL-tall m3/l: 168000
YL-group: 5
Safety phrases: 38 42 210
In case of insufficient ventilation, wear suitable respiratory
equipment. During fumigation/spraying wear suitable respiratory
equipment. Use compressed air- or fresh air line breathing
apparatus in confined spaces.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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