Material Safety Data Sheet
Date Printed: 20/NOV/2005
Date Updated: 13/MAR/2004
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
1 - Product and Company Information
Product Name CALCIUM IONOPHORE A23187 FREE ACID
Product Number C7522
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
CALCIMYCIN A23187 FREE ACID* 52665-69-7 258-084-1 None
Molecular Weight 523.6 AMU
Synonyms A 23187 * Antibiotic A23187 * Calcimycin *
Calcium ionophore A 23187 * Ionophore A23187
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Irritating to eyes, respiratory system and skin.
4 - First Aid Measures
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: White
Form: Fine crystals
Property Value At Temperature or Pressure
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
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Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
Partition Coefficient N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Miscellaneous Data N/A
10 - Stability and Reactivity
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: DM4676000
9200 UG/KG 9200 UG/KG
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Behavioral:Muscle weakness. Sense Organs and Special Senses
(Nose, Eye, Ear, and Taste):Eye:Etosis. Sense Organs and Special
Senses (Nose, Eye, Ear, and Taste):Eye:Etosis. Behavioral:Muscle
weakness. Lungs, Thorax, or Respiration:Dyspnea.
10 MG/KG 10 MG/KG
4500 UG/KG 4500 UG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Depending on the intensity and duration of exposure, effects may
vary from mild irritation to severe destruction of tissue.
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ROUTE OF EXPOSURE
Skin Contact: Causes severe skin irritation.
Eye Contact: Causes severe eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
Multiple Routes: Harmful if swallowed, inhaled, or absorbed
CONDITIONS AGGRAVATED BY EXPOSURE
The toxicological properties have not been thoroughly
12 - Ecological Information
No data available.
13 - Disposal Considerations
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
14 - Transport Information
Non-hazardous for road transport.
Non-hazardous for sea transport.
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xi
Irritating to eyes, respiratory system and skin.
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
16 - Other Information
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
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paper copies for internal use only.
For R&D use only. Not for drug, household or other uses.
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