Material Safety Data Sheet
1. Chemical product and company identification
Product name ACRYLONITRILE
MSDS # 0000000892
Code 0000000892 (NAP)
Product use Industrial applications
Supplier INEOS USA LLC
2600 South Shore Blvd.
League City, Texas 77573
EMERGENCY SPILL 1 (800) 424-9300
Outside the US: +1 703-527-3887 (CHEMTREC)
INFORMATION:
OTHER PRODUCT 1 (866) 363-2454
http://techservice.innovene.com
INFORMATION
2. Composition/information on ingredients
Ingredient name CAS # % by weight
Acrylonitrile 107-13-1 >99.4
Water 7732-18-5 <0.6
3. Hazards identification
Physical state Liquid. (Colorless.)
Color Colorless.
Emergency overview DANGER! CORROSIVE.
EXTREMELY FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
CAUSES SKIN BURNS.
Toxic if swallowed.
TOXIC IF ABSORBED THROUGH SKIN.
TOXIC IF INHALED.
CAUSES EYE IRRITATION.
MAY CAUSE ALLERGIC SKIN REACTION.
CANCER HAZARD
CONTAINS MATERIAL WHICH CAN CAUSE CANCER
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: BLOOD, LIVER, CARDIOVASCULAR
SYSTEM, CENTRAL NERVOUS SYSTEM
Do not ingest. Do not get in eyes, on skin or on clothing. Do not breathe vapor or mist. Keep
away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation.
Wash thoroughly after handling. Risk of cancer depends on duration and level of exposure.
Routes of entry Dermal contact. Eye contact. Inhalation. Ingestion.
Potential health effects
Eyes Causes severe eye irritation. Liquid will cause conjunctival irritation and corneal damage. Vapour
may cause conjunctival irritation.
Skin Toxic if absorbed through skin. Corrosive. Causes skin burns May cause allergic skin reaction.
Liquid or vapor may be absorbed in toxicologically significant amounts. Skin absorption may be a
significant route for exposure. Absorption will be rapid. Effects will be similar to those resulting
from ingestion. Contains material which can cause cancer.
Inhalation Toxic if inhaled. Irritating to respiratory system. May cause headache, weakness, dizziness,
shortness of breath, cyanosis, rapid heart beat, unconsciousness, and possible death. Odor does
not provide reliable warning of exposure. Contains material which can cause cancer.
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Ingestion Toxic if swallowed. Causes severe irritation or burns of the mouth, throat, and esophagus. May
cause headache, weakness, dizziness, shortness of breath, cyanosis, rapid heart beat,
unconsciousness, and possible death. Ingestion may irritate the gastrointestinal tract and may
cause nausea and vomiting. Contains material which can cause cancer
See toxicological information (section 11)
4. First aid measures
Eye contact Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. If
symptomatic, treat as described under inhalation. Get medical attention immediately.
Skin contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Wash contaminated clothing before reusing. Do not
use protective clothing made of leather, natural or nitrile rubber. If such clothing is contaminated
with acrylonitrile, it should be destroyed by burning. Note that contaminated clothing may be a fire
hazard. Get medical attention immediately.
Inhalation If inhaled, remove to fresh air. Get medical attention immediately.
Cyanide first aid treatment (containing amyl nitrite capsules) must be available at site. Authorized
personnel, acting under standing instructions, may break a capsule of amyl nitrite in a handkerchief
and hold it about one inch from the patient's mouth and nostrils for 30 seconds every minute. If not
breathing, if irregular breathing, or respiratory arrest occurs provide artificial respiration or oxygen
by trained personnel. WARNING: It may be hazardous to the person providing aid to give mouth-
to-mouth resuscitation when the inhaled material is toxic, infectious or corrosive.
Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Get medical attention immediately. Do not wait for symptoms to
develop.
Notes to physician Notes to Physician: The onset of symptoms is typically delayed for up to several hours after oral
ingestion, inhalation or dermal contact. The prolonged duration of symptoms, regardless of route
of exposure, may require repeat doses of cyanide antidotes. Treat as in cyanide poisoning.
Toxicity may be delayed due to metabolic release of cyanide. Support respiratory and
cardiovascular function.
Administer 100% oxygen and monitor blood gases. If symptomatic administer amyl nitrite until
intravenous access is established, then inject sodium nitrite (10ml of a 3% solution over 5 minutes)
. Monitor blood pressure closely as sodium nitrite is a potent vasodilator. Follow the sodium nitrite
directly with intravenous sodium thiosulfate (25% solution), 1.65ml(412mg)/kg of body weight for
those under 25kg and 12.5gm (50ml) for those over 25kg. Give at a rate of 2.5-5.0ml/minute. If
signs of poisoning persist or reappear, repeat nitrite and thiosulfate injections 30 minutes to an
hour later at half the original dose. Monitor blood methemoglobin levels. They should not be
allowed to exceed 30-40%. Even when the patient seems perfectly well, the medication may be
given for prophylactic purposes 2 hours after the first injections. Whenever the cyanide antidote kit
is used the patient should be admitted to an intensive care unit. Monitor arterial gases. Treat
lactic acidosis and metabolic acidosis with sodium bicarbonate. Treat seizures with diazepam,
phenytoin, or phenobarbital. Hyperbaric oxygen and hemodialysis may be helpful in severe cases
not responsive to supportive and antidotal therapy. Hypotension secondary to nitrites should be
treated with intravenous fluids and the Trendelenburg position. If pulmonary edema develops,
maintain ventilation and oxygenation with close arterial gas monitoring. PEEP or CPAP may be
necessary if pO2 remains below 50mm Hg. Avoid net positive fluid balance. Blood cyanide and
serum thiosulfate levels will be helpful for documentation although they might not be available for
several days. Do not induce emesis in cases of ingestion. Gastric lavage may be performed with
a large bore tube after endotrachael intubation. Administer activated charcoal slurry to prevent
absorption. Administer one dose of a saline cathartic or sorbitol mixed with charcoal or given
separately. Patients should be observed a minimum of 24-48 hours.
5. Fire-fighting measures
Flammability of the product Flammable.
Auto-ignition temperature 481 癈
Flash point -1 癈 (Closed cup) Pensky-Martens.
Explosion limits Lower: 3 %
Upper: 17 %
Products of combustion These products are carbon oxides (CO, CO2) (carbon monoxide, carbon dioxide), nitrogen oxides
(NO, NO2...), Hydrogen Cyanide (HCN). Evolves toxic fumes when heated to the decomposition
state. When heated to decomposition it emits acrid smoke and irritating fumes.
Unusual fire/explosion Extremely flammable liquid and vapor. Vapor may cause flash fire. Vapors may accumulate in low
or confined areas, travel considerable distance to source of ignition and flash back. Runoff to
hazards
sewer may create fire or explosion hazard.
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Explosive in presence of open flames, sparks and static discharge
Vapors may accumulate in low or confined areas, travel considerable distance to source of ignition
and flash back.
Runoff to sewer may create fire or explosion hazard.
May re-ignite itself after fire is extinguished.
Fire-fighting media and In case of fire, use water fog, foam, dry chemicals, or carbon dioxide. Water may be ineffective.
Do not use water jet. DO NOT FIGHT FIRE WHEN IT REACHES MATERIAL. Withdraw from fire
instructions
and let it burn. Promptly isolate the scene by removing all persons from the vicinity of the incident
if there is a fire. First move people out of line-of-sight of the scene and away from windows. Cool
containing vessels with flooding quantities of water until well after fire is out.
Protective clothing (fire) Fire-fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full
turnout gear. Wear butyl rubber boots and full chemical protective suit if high vapor concentration
or significant liquid splash potential exists.
6. Accidental release measures
Personal precautions Immediately contact emergency personnel. Eliminate all ignition sources. Keep unnecessary
personnel away. Use suitable protective equipment (See Section: "Exposure controls/personal
protection"). Follow all fire fighting procedures (See Section: "Fire-fighting measures"). Do not
touch or walk through spilled material.
Environmental If emergency personnel are unavailable, contain spilled material. For small spills add absorbent
(soil may be used in the absence of other suitable materials) scoop up material and place in a
precautions and clean-up
sealed, liquid-proof container for disposal. For large spills dike spilled material or otherwise
methods
contain material to ensure runoff does not reach a waterway. Place spilled material in an
appropriate container for disposal. Avoid contact of spilled material with soil and prevent runoff
entering surface waterways. See Section 13 for Waste Disposal Information.
Personal protection in Butyl rubber is the protective material of choice. Protective clothing must be made from
materials specifically recommended for protection against acrylonitrile penetration. Consult your
case of a large spill
local safety specialist for a list of recommended materials. Wear butyl rubber boots and full
chemical protective suit if high vapor concentration or significant liquid splash potential exists.
Wear full face respirator for eye protection if high vapor concentration or significant liquid splash
potential exists. A self-contained breathing apparatus should be used to avoid inhalation of the
product.
7. Handling and storage
Handling Use suitable protective equipment (See Section: "Exposure controls/personal protection"). Do not
ingest. Do not get in eyes, on skin or on clothing. Use only with adequate ventilation. Do not
breathe vapor or mist. Cyanide first aid treatment (containing amyl nitrite capsules) must be
available at site. Keep away from heat, sparks and flame. To avoid fire or explosion, dissipate
static electricity during transfer by grounding and bonding containers and equipment before
transferring material. Use explosion-proof electrical (ventilating, lighting and material handling)
equipment. Wash thoroughly after handling.
Storage Store in a segregated and approved area. Store in a cool, well-ventilated area away from
incompatible materials and ignition sources. Suitable storage materials are mild steel. stainless
steel. Do not store in copper and its alloys. Keep container tightly closed and sealed until ready
for use. Inhibit with: p-Methoxyphenol (MEHQ). To maintain inhibitor activity, oxygen must not be
eliminated from the atmosphere above the product. If the explosion risk posed by storing under air
is unacceptable, use oxygen depleted air (5% oxygen minimum). Check inhibitor level periodically.
8. Exposure controls/personal protection
Occupational exposure
limits
Ingredient name Occupational exposure limits
ACGIH TLV (United States, 1/2004). Skin
Acrylonitrile
TWA: 4.3 mg/m3 8 hour(s).
TWA: 2 ppm 8 hour(s).
OSHA Final Rule (United States, 1989). Skin
CEIL: 10 ppm 15 minute(s).
OSHA PEL (United States, 8/1997). Skin
CEIL: 10 ppm
TWA: 2 ppm 8 hour(s).
Water None assigned.
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Handle only in totally enclosed systems. Provide exhaust ventilation or other engineering
Control Measures
controls to keep the relevant airborne concentrations below their respective occupational
exposure limits. Ensure that eyewash stations and safety showers are close to the work-station
location.
Hygiene measures Wash hands after handling compounds and before eating, smoking, using lavatory, and at the
end of day.
Personal protection
Eyes Chemical splash goggles. Wear full face respirator for eye protection if high vapor concentration
or significant liquid splash potential exists. A respirator is not needed under normal and intended
conditions of product use.
Skin and body Do not get on skin or clothing. Butyl rubber is the protective material of choice. Protective clothing
must be made from materials specifically recommended for protection against acrylonitrile
penetration. Consult your local safety specialist for a list of recommended materials. Wear butyl
rubber boots and full chemical protective suit if high vapor concentration or significant liquid splash
potential exists. Do not use protective clothing made of leather, natural or nitrile rubber. If such
clothing is contaminated with acrylonitrile, it should be destroyed by burning. Note that
contaminated clothing may be a fire hazard. Wash thoroughly after handling.
Respiratory Use only with adequate ventilation. Do not breathe vapor or mist. Wear full face respirator.
Hands Wear gloves that cannot be penetrated by chemicals or oil. (Butyl rubber gloves.)
The correct choice of protective gloves depends upon the chemicals being handled, the conditions
of work and use, and the condition of the gloves (even the best chemically resistant glove will
break down after repeated chemical exposures). Most gloves provide only a short time of
protection before they must be discarded and replaced. Because specific work environments and
material handling practices vary, safety procedures should be developed for each intended
application. Gloves should therefore be chosen in consultation with the supplier/manufacturer and
with a full assessment of the working conditions.
Consult your supervisor or S.O.P. for special handling directions
Consult local authorities for acceptable exposure limits.
9. Physical and chemical properties
Physical state Liquid. (Colorless.)
pH 6 to 7.5 at 5%
Odor Pungent. (Slight.)
Color Colorless.
Boiling point / Range 77.3 癈
Melting point / Range -83.5 癈
806 kg/m3 (0.806 g/cm3) at 20癈
Density
Vapor pressure 11.07 kPa at 20癈
Vapor Density (Air = 1) 1.83
Solubility 7.35 at 20癈
Dispersibility properties See solubility in water.
LogKow The product is more soluble in water; log(octanol/water) =0.92
Viscosity Dynamic: 0 Pa穝 (0.34 cP) at 25癈
10. Stability and reactivity
Stability and reactivity Must be inhibited to prevent hazardous polymerization. Stable under recommended storage and
handling conditions (See Section: "Handling and storage").
Conditions to avoid Keep away from heat and direct sunlight. Avoid all possible sources of ignition (spark or flame).
Incompatibility with various Highly reactive with oxidizing agents, reducing agents, acids, alkalis. This product may polymerize
with explosive violence. May polymerize on exposure to sunlight., absence of oxygen., peroxides,
substances
alkalis, strong acids, Ammonia., Bromine., Copper.
Hazardous decomposition These products are: carbon oxides (CO, CO2) (carbon monoxide, carbon dioxide) nitrogen oxides
(NO, NO2...). When heated to decomposition it emits acrid smoke and irritating fumes. Evolves
products
toxic fumes when heated to the decomposition state.
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Hazardous polymerization Yes. Product stabilized but may polymerize readily. Avoid depletion of inhibitor. Inhibit with:
p-Methoxyphenol (MEHQ). To maintain inhibitor activity, oxygen must not be eliminated from the
atmosphere above the product. If the explosion risk posed by storing under air is unacceptable,
use oxygen depleted air (5% oxygen minimum). Check inhibitor level periodically.
11. Toxicological information
Ingredient name Test Result Route Species
Acrylonitrile LD50 81 mg/kg Oral Rat
LD50 226 to 250 mg/kg Dermal Rabbit
LC50 557 ppm (4 hour Inhalation Rat
(s))
LCLo >1008 ppm (1 Inhalation Rat
hour(s))
Chronic toxicity
CANCER HAZARD
Carcinogenic
CONTAINS MATERIAL WHICH CAN CAUSE CANCER
effects
Risk of cancer depends on duration and level of exposure.
Classified 2B (Possible for human.) by IARC: [Acrylonitrile]
Classified 2 (Reasonably Anticipated To Be Human Carcinogens.) by NTP: [Acrylonitrile]
Classified + (Proven) by OSHA: [Acrylonitrile]
Acrylonitrile has been shown to be weekly mutagenic in in-vitro systems: these findings have not
Mutagenic
been reflected in in-vivo studies.
effects
Adverse effects on the developing fetus or on reproduction have been reported in experimental
Reproductive
animal studies at doses that were toxic to the mother.
effects
Embryotoxic and teratogenic effects have been observed in the offspring of experimental animals
Teratogenic
exposed to maternally toxic doses of acrylonitrile.
effects
Other information Substance has been reported to have skin sensitisation potential when tested by the following
procedures:- Magnusson and Kligman.
Studies conducted in China have reported higher than expected rates of reproductive effects
and abnormal fetal development among acrylonitrile workers. INNOVENE has not made a
determination about the reliability of these studies because important questions remain to be
answered about the data collection methodology, chemical exposures, social and lifestyle
influences and inconsistencies with other information.
While hydrogen cyanide alone is not known to affect hearing, simultaneous exposure to high
levels of noise and concentrations of hydrogen cyanide at levels above the occupational
exposure limit resulted in significant hearing loss in experimental animals. The significance of
this finding to humans is not known.
12. Ecological information
Ecotoxicity 10.1 mg/l [LC50], 96 hour(s) [Fish (Minnows)].
10.95 mg/l [IC50], 72 hour(s) [Algae].
Persistence/degradability This product is not expected to bioaccumulate through food chains in the environment. Readily
biodegradable
Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Soil/water partition 0.92
coefficient (KOC)
13. Disposal considerations
Waste information Dispose of in accordance with all applicable local and national regulations. Avoid contact of spilled
material and runoff with soil and surface waterways. Consult an environmental professional to
determine if local, regional or national regulations would classify spilled or contaminated materials
as hazardous waste. Use only approved transporters, recyclers, treatment, storage or disposal
facilities. Comply with all local, regional, and national laws pertaining to waste management.
Consult your local or regional authorities.
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14. Transport information
International transport regulations
Regulatory UN Packing group Label
Proper shipping Class Additional
information number name information
DOT Acrylonitrile, 3 (6.1) I Reportable
UN1093
stabilised
Classification quantity
100 lbs. (45.36 kg)
TDG UN1093 Acrylonitrile, 3 (6.1) I -----
stabilized
Classification
IMDG Acrylonitrile, 3 (6.1) I
UN1093 -----
stabilized
Classification
IATA Quantity limitation
UN1093 Acrylonitrile, 3 (6.1) I
stabilized
Classification - Passenger
Aircraft
Forbidden
Quantity limitation
- Cargo Aircraft
30 L
Remarks
FORBIDDEN ON
PASSENGER
AIRCRAFT
15. Regulatory information
U.S. Federal regulations US INVENTORY (TSCA): Listed on inventory.
SARA Title III Section 302 Extremely Hazardous Substances (40 CFR Part 355): Acrylonitrile
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: ACRYLONITRILE :
Fire hazard, reactive, Immediate (Acute) Health Hazard, Delayed (Chronic) Health Hazard
SARA 313
Product name CAS number Concentration
Form R - Reporting ACRYLONITRILE 100
requirements
Supplier notification ACRYLONITRILE 100
CERCLA Sections 102a/103 Hazardous Substances (40 CFR Part 302.4):: ACRYLONITRILE :
100 lbs. (45.36 kg)
State regulations Massachusetts RTK:Acrylonitrile
New Jersey:Acrylonitrile
Pennsylvania RTK:Acrylonitrile (special hazard, environmental hazard, generic environmental
hazard)
WARNING: This product contains a chemical known to the State of California to cause cancer.
ACRYLONITRILE ; Acrylonitrile
Inventories AUSTRALIAN INVENTORY (AICS): Listed on inventory.
CANADA INVENTORY (DSL): Listed on inventory.
CHINA INVENTORY (IECS): Listed on inventory.
EC INVENTORY (EINECS/ELINCS): Listed on inventory.
JAPAN INVENTORY (ENCS): Listed on inventory.
KOREA INVENTORY (ECL): Listed on inventory.
PHILIPPINE INVENTORY (PICCS): Listed on inventory.
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16. Other information
Label requirements DANGER! CORROSIVE.
EXTREMELY FLAMMABLE LIQUID AND VAPOR.
VAPOR MAY CAUSE FLASH FIRE.
CAUSES SKIN BURNS.
Toxic if swallowed.
TOXIC IF ABSORBED THROUGH SKIN.
TOXIC IF INHALED.
CAUSES EYE IRRITATION.
MAY CAUSE ALLERGIC SKIN REACTION.
CANCER HAZARD
CONTAINS MATERIAL WHICH CAN CAUSE CANCER
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: BLOOD, LIVER, CARDIOVASCULAR
SYSTEM, CENTRAL NERVOUS SYSTEM
Health 4 *
HMIS?Rating : National Fire
3 Fire hazard
Flammability 3 Protection
4 2
Health Instability
Physical 2 Association Specific hazard
Hazard (U.S.A.)
Personal X
protection
History
Date of issue 06/28/2006.
Date of previous issue 01/18/2006.
Prepared by Product Stewardship
Notice to reader
NOTICE : This Material Safety Data Sheet is based upon data considered to be accurate at the time of its preparation. Despite
our efforts, it may not be up to date or applicable to the circumstances of any particular case. We are not responsible for any
damage or injury resulting from abnormal use, from any failure to follow appropriate practices or from hazards inherent in the
nature of the product.
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