Material Safety Data Sheet
Phenylhydrazium Chloride
ACC# 88685
Section 1 - Chemical Product and Company Identification
MSDS Name: Phenylhydrazium Chloride
Catalog Numbers: AC151550000, AC151550050, AC151551000, AC151555000
Synonyms: Hydrazine, phenyl-, hydrochloride; Hydrazine, phenyl-, monohydrochloride;
Phenylhydrazine monohydrochloride; Phenylhydrazin hydrochlorid; Phenylhydrazinium
chloride
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
CAS# Chemical Name Percent EINECS/ELINCS
59-88-1 Phenylhydrazium Chloride 100.0 200-444-7
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white to cream crystalline powder.
Warning! Contains material which may cause cancer based on animal data. Possible risks
of irreversible effects. Causes respiratory tract irritation. Harmful if swallowed, inhaled, or
absorbed through the skin. Causes eye and skin irritation. May cause allergic skin reaction.
May cause blood abnormalities. May cause liver and kidney damage. Light sensitive. Air
sensitive. Dangerous for the environment.
Target Organs: Blood, kidneys, liver, lungs, eyes, skin.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. Harmful if absorbed through the skin. May cause skin
sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Substance is rapidly absorbed through the skin. May cause eczematous dermatitis with
swelling and vesiculation.
Ingestion: Harmful if swallowed. May cause liver and kidney damage. Causes
gastrointestinal tract irritation. May cause systemic effects by ingestion: blood hemolysis
with or without anemia, methemoglobinemia-carboxyhemoglobinemia, and pulmonary
changes. May cause central nervous system stimulation.
Inhalation: Harmful if inhaled. Causes respiratory tract irritation. May cause effects similar
to those described for ingestion. Acute exposure to low concentrations of hydrazines may
cause and produce bronchial mucous destruction, pulmonary edema, cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood) and possible death.
Chronic: Possible cancer hazard based on tests with laboratory animals. Prolonged or
repeated skin contact may cause dermatitis. Prolonged or repeated eye contact may cause
conjunctivitis. May cause methemoglobinemia, which is characterized by chocolate-brown
colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due
to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death.
May cause fetal effects. May cause cancer according to animal studies. Laboratory
experiments have resulted in mutagenic effects. Chronic inhalation may cause liver damage.
Section 4 - First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least
15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless
directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood. Monitor arterial blood
gases, chest x-ray, pulmonary function tests if respiratory tract irritation or respiratory
depression is evident. Monitor methemoglobin and blood sugar levels.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a
fire, irritating and highly toxic gases may be generated by thermal decomposition or
combustion. Use water spray to keep fire-exposed containers cool. This material in sufficient
quantity and reduced particle size is capable of creating a dust explosion.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding fire.
Use carbon dioxide, dry chemical, or water fog.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 1
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Place under an inert atmosphere.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Minimize dust generation and accumulation. Do
not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or
inhale. Store protected from light. Handle under an inert atmosphere. Store protected from
air. Use only in a chemical fume hood.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away
from incompatible substances. Do not expose to air. Store protected from light. Store under
an inert atmosphere.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with
an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Phenylhydrazium
none listed none listed none listed
Chloride
OSHA Vacated PELs: Phenylhydrazium Chloride: No OSHA Vacated PELs are listed for this
chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and
ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever
workplace conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
Physical State: Crystalline powder
Appearance: white to cream
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:250 deg C
Decomposition Temperature:> 245 deg C
Solubility: Soluble.
Specific Gravity/Density:Not available.
Molecular Formula:C6H8N2.HCl
Molecular Weight:144.61
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. May violently
decompose at temperatures above 190癈.
Conditions to Avoid: Incompatible materials, light, dust generation, exposure to air,
temperatures above 90癈.
Incompatibilities with Other Materials: Strong oxidizing agents, bases, lead dioxide, air,
common metals (expect aluminum).
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon
monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 59-88-1: MV9000000
LD50/LC50:
CAS# 59-88-1:
Oral, mouse: LD50 = 2100 mg/kg;
.
CAS# 100-63-0: Oral, rat: LD50 = 188 mg/kg.; Inhalation, rat: LC50 = 2610 mg/m3. (The
toxicity of this product is partially based on the hazards associated with Phenylhydrazine
(CAS# 100-63-0).
Carcinogenicity:
CAS# 59-88-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information found
Teratogenicity: Intraperitoneal, rat: TDLo = 30 mg/kg (female 17-19 day(s) after
conception) Effects on Newborn - behavioral.
Reproductive Effects: No information found
Mutagenicity: Oral, mouse: TDLo = 8000 mg/kg/42W-I (Tumorigenic - neoplastic by
RTECS criteria--Lungs, Thorax, or Respiration - Tumors); Oral, mouse: TD = 10
gm/kg/58W-C (Tumorigenic - neoplastic by RTECS criteria--Vascular - Tumors and Blood -
Lymphoma, including Hodgkin's disease); Mutation in microorganisms: Salmonella
typhimurium = 800 ug/plate; DNA repair: Rat, liver = 10 umol/L.
Neurotoxicity: No information found
Other Studies:
Section 12 - Ecological Information
Ecotoxicity: No data available. No information available.
Environmental: The environmental hazards of phenylhydrazine may be seen in this
product.
Physical: No information available.
Other: No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local hazardous waste
regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOT Canada TDG
TOXIC SOLID ORGANIC NOS
Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
(PHENYLHYDRAZINE HYDROCHLORIDE)
Hazard Class: 6.1 6.1
UN Number: UN2811 UN2811
Packing Group: III III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 59-88-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
CAS# 59-88-1: 1000 lb TPQ (lower threshold); 10000 lb TPQ (upper thres hold)
SARA Codes
CAS # 59-88-1: immediate, delayed, reactive.
Section 313 No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the
CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 59-88-1 can be found on the following state right to know lists: New Jersey,
Pennsylvania, Massachusetts.
California Prop 65
California No Significant Risk Level: CAS# 59-88-1: 1.4 鎔/day NSRL
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
TN
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin and if
swallowed.
R 36/38 Irritating to eyes and skin.
R 43 May cause sensitization by skin contact.
R 45 May cause cancer.
R 50 Very toxic to aquatic organisms.
R 48/23/24/25 Toxic : danger of serious damage to health by
prolonged exposure through inhalation, contact with skin and if
swallowed.
Safety Phrases:
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 53 Avoid exposure - obtain special instructions before use.
S 61 Avoid release to the environment. Refer to special instructions
/safety data sheets.
WGK (Water Danger/Protection)
CAS# 59-88-1: 3
Canada - DSL/NDSL
CAS# 59-88-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2B, D2A.
This product has been classified in accordance with the hazard criteria of the Controlled
Products Regulations and the MSDS contains all of the information required by those
regulations.
Canadian Ingredient Disclosure List
Section 16 - Additional Information
MSDS Creation Date: 12/12/1997
Revision #5 Date: 2/15/2006
The information above is believed to be accurate and represents the best information currently available to us. However,
we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and
we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third
party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if
Fisher has been advised of the possibility of such damages.
|