MATERIAL SAFETY DATA SHEET Page 1 of 7
MATERIAL SAFETY DATA SHEET
N-Methylaniline, 98%
97343
**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: N-Methylaniline, 98%
N-Methyl Benzeneamine
Company Identification: Acros Organics N.V.
One Reagent Lane
Fairlawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 100-61-8 |N-Methylaniline | 98 | 202-870-9 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 23/24/25 33
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Appearance: clear yellow. Flash Point: 78 deg C.
Caution! Combustible liquid. Air sensitive. May cause
methemoglobinemia. May cause central nervous system effects. May
cause eye and skin irritation. May cause respiratory and digestive
tract irritation.
Target Organs: Blood, central nervous system.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Methemoglobinemia is characterized by dizziness,
drowsiness, headache, breath shortness, cyanosis with bluish skin,
rapid heart rate and chocolate-brown colored blood. Effects may be
delayed.
Inhalation:
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Effects may be delayed. May cause respiratory tract irritation. May
cause methemoglobinemia, cyanosis, convulsions, tachycardia,
dyspnea, and death.
Chronic:
May cause methemoglobinemia, which is characterized by
chocolate-brown colored blood, headache, weakness, dizziness, breath
shortness, cyanosis, rapid heart rate, unconsciousness and possible
death. Prolonged or repeated exposure may cause nausea, dizziness,
and headache. Effects may be delayed.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower lids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at
least 15 minutes while removing contaminated clothing and shoes. Wash
clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid. DO NOT use mouth-to-mouth respiration.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
blue depending on the methemoglobinemia concentration in the blood.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Combustible Liquid.
Vapors may be heavier than air. They can spread along the ground and
collect in low or confined areas. Contact with metals may evolve
flammable hydrogen gas. Containers may explode when heated.
Extinguishing Media:
Do NOT get water inside containers. For small fires, use dry
chemical, carbon dioxide, or water spray. For large fires, use dry
chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Cool containers with flooding quantities of water until well after
fire is out.
Autoignition Temperature: 500 deg C ( 932.00 deg F)
Flash Point: 78 deg C ( 172.40 deg F)
(estimated) Health: 1; Flammability: 2; Reactivity: 0
Explosion Limits, Lower: N/A
Upper: N/A
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material, (e.g., dry sand or earth), then
place into a chemical waste container. Avoid runoff into storm
sewers and ditches which lead to waterways. Clean up spills
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MATERIAL SAFETY DATA SHEET Page 3 of 7
immediately, observing precautions in the Protective Equipment
section. Remove all sources of ignition. Provide ventilation. Do not
get water inside containers.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use only in a well ventilated area.
Avoid contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Keep
container tightly closed. Avoid contact with heat, sparks and flame.
Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or
open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Keep container closed when not in use. Store in a tightly
closed container. Store in a cool, dry, well-ventilated area away
from incompatible substances. Store under an inert atmosphere.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
| Chemical Name | ACGIH | NIOSH |OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| N-Methylaniline |0.5 ppm ; 2.2 |0.5 ppm TWA; 2 |2 ppm TWA; 9 |
| |mg/m3; skin - | mg/m3 TWA 100 | mg/m3 TWA |
| |potential for |ppm IDLH | |
| |cutaneous | | |
| |absorption | | |
+--------------------+-------------------+-------------------+-----------------+
OSHA Vacated PELs:
N-Methylaniline:
0.5 ppm TWA; 2 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
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MATERIAL SAFETY DATA SHEET Page 4 of 7
Appearance: clear yellow
Odor: ammonia-like
pH: Not available.
Vapor Pressure: 0.4 mbar @ 20 C
Vapor Density: 3.7
Evaporation Rate: Not available.
Viscosity: Not available.
Boiling Point: 196 deg C @ 760.00mm Hg
Freezing/Melting Point: -57 deg C
Decomposition Temperature: Not available.
Solubility: slightly soluble
Specific Gravity/Density: .9890g/cm3
Molecular Formula: C7H9N
Molecular Weight: 107.15
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. Substance undergoes
color change upon exposure to air.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess
heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, acid anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 100-61-8: BY4550000
LD50/LC50:
CAS# 100-61-8: Oral, mouse: LD50 = 300 mg/kg.
Carcinogenicity:
N-Methylaniline -
ACGIH: A3 - Animal Carcinogen (listed as ANILINE).
California: carcinogen - initial date 1/1/90 (listed as ANILINE).
NIOSH: occupational carcinogen (listed as ANILINE)
OSHA: Possible select carcinogen (listed as ANILINE).
IARC: Group 3 carcinogen (listed as ANILINE).
Epidemiology:
No data available.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Neurotoxicity:
No data available.
Mutagenicity:
No data available.
Other Studies:
No data available.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Not available.
Environmental Fate:
Not available.
Physical/Chemical:
Not available.
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Other:
Not available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration of Contaminants:
None listed.
RCRA D-Series Chronic Toxicity Reference Levels: None
listed.
RCRA F-Series: None listed.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Not listed as a material banned from land disposal
according to RCRA.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
Shipping Name: N-METHYLANILINE
Hazard Class: 6.1
UN Number: UN2294
Packing Group: III
IMO
Shipping Name: N-METHYLANILINE
Hazard Class: 6.1
UN Number: 2294
Packing Group: III
IATA
Shipping Name: N-METHYLANILINE
Hazard Class: 6.1
UN Number: 2294
Packing Group: III
RID/ADR
Shipping Name: N-METHYLANILINE
Dangerous Goods Code: 6.1(12C)
UN Number: 2294
Canadian TDG
Shipping Name: N METHYLANILINE
Hazard Class: 6.1
UN Number: UN2294
**** SECTION 15 - REGULATORY INFORMATION ****
US FEDERAL
TSCA
CAS# 100-61-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 100-61-8: flammable.
Section 313
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MATERIAL SAFETY DATA SHEET Page 6 of 7
This material contains N-Methylaniline (listed as ANILINE), 98%,
(CAS# 100-61-8) which is subject to the reporting requirements of
Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 100-61-8 listed as ANILINE is listed as a hazardous air
pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 100-61-8 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
STATE
N-Methylaniline can be found on the following state right to know
lists: California, New Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains N-Methylaniline, listed as `ANILINE',
a chemical known to the state of California to cause cancer.
California No Significant Risk Level:
CAS# 100-61-8: no significant risk level = 100 ug/day (listed
under ANILINE)
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 33 Danger of cumulative effects.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident of if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and/or its container must be
disposed of as hazardous waste.
S 28A After contact with skin, wash immediately with
plenty of water.
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 100-61-8: 1
Canada
CAS# 100-61-8 is listed on Canada's DSL/NDSL List.
This product does not have a WHMIS classification.
CAS# 100-61-8 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 100-61-8:. OEL-ARAB Republic of Egypt:TWA 2 ppm (9 mg/m3);Skin.
OEL-AUSTRALIA:TWA 0.5 ppm (2 mg/m3);Skin. OEL-BELGIUM:TWA 0.5 ppm (2.2
mg/m3);Skin. OEL-DENMARK:TWA 0.5 ppm (2.25 mg/m3);Skin. OEL-FRANCE:TW
A 0.5 ppm (2 mg/m3);Skin. OEL-GERMANY:TWA 0.5 ppm (2 mg/m3);Skin. OEL-
THE NETHERLANDS:TWA 0.5 ppm (2 mg/m3). OEL-SWITZERLAND:TWA 0.5 ppm (2.
2 mg/m3);STEL 1.0 ppm;Skin. OEL-TURKEY:TWA 2 ppm (9 mg/m3);Skin. OEL-U
NITED KINGDOM:TWA 0.5 ppm (2 mg/m3);Skin. OEL IN BULGARIA, COLOMBIA, J
ORDAN, KOREA check ACGIH TLV. OEL IN NEW ZEALAND, SINGAPORE, VIETNAM c
heck ACGI TLV
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MATERIAL SAFETY DATA SHEET Page 7 of 7
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 2/01/1996 Revision #4 Date: 8/06/1998
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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