SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 04/25/2008
Date Updated: 02/04/2006
Version 1.3
Section 1 - Product and Company Information
Product Name N-METHYLANILINE, 99+%
Product Number 236233
Brand ALDRICH
Company Sigma-Aldrich
Address 3050 Spruce Street
SAINT LOUIS MO 63103 US
Technical Phone: 800-325-5832
Fax: 800-325-5052
Emergency Phone: 314-776-6555
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
N-METHYLANILINE 100-61-8 No
Formula C7H9N
Synonyms Anilinomethane * Benzenamine, N-methyl- (9CI) *
(Methylamino)benzene * N-Methylaminobenzene *
Methylaniline * N-Methylaniline (ACGIH) *
N-Methylbenzenamine * Methylphenylamine *
N-Methylphenylamine * Monomethylaniline *
N-Monomethylaniline * Monomethyl aniline (OSHA) *
N-Phenylmethylamine
RTECS Number: BY4550000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic.
Toxic by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Combustible. Readily absorbed through skin.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
EYE EXPOSURE
Assure adequate flushing of the eyes by separating the eyelids
with fingers.
Section 5 - Fire Fighting Measures
FLASH POINT
185 癋 85 癈 Method: closed cup
AUTOIGNITION TEMP
500 癈
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: For small (incipient) fires, use media such as
"alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large
quantities (flooding) of water applied as a mist or spray; solid
streams of water may be ineffective. Cool all affected
containers with flooding quantities of water.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
EXPOSURE HAZARD(S)
Material: Irritant. Harmful liquid. Toxic.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe vapor. Do not get in eyes, on
skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed. Keep away from heat and open
flame. Store in a cool dry place.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
PERSONAL PROTECTIVE EQUIPMENT
Other: Wear appropriate government approved respirator,
chemical-resistant gloves, safety goggles, other protective
clothing.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
EXPOSURE LIMITS, RTECS
Country Source Type Value
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USA ACGIH TWA 0.5 PPM
Remarks: Skin
USA MSHA Standard-air TWA 2 PPM (9 MG/M3) (SKIN)
USA OSHA. PEL 8H TWA 2 PPM (9 MG/M3) (SKIN)
New Zealand OEL
Remarks: check ACGIH TLV
USA NIOSH TWA 0.5 PPM (SK)
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 2 MG/M3
Poland NDSCh -
Poland NDSP -
Section 9 - Physical/Chemical Properties
Appearance Color: Light yellow-green
Form: Clear liquid
Property Value At Temperature or Pressure
Molecular Weight 107.16 AMU
pH 7.6 Concentration: 1 g/l
BP/BP Range 192.0 - 197.0 癈
MP/MP Range - 57.0 癈
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 0.985 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point 185 癋 85 癈 Method: closed cup
Explosion Limits N/A
Flammability N/A
Autoignition Temp 500 癈
Refractive Index 1.571
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Solubility in Water:30 mg/ml H2O
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Materials to Avoid: Strong oxidizing agents Carbon dioxide.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide,
and nitrogen oxides.
Section 11 - Toxicological Information
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ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Multiple Routes: Harmful if swallowed, inhaled, or absorbed
through skin. Vapor or mist is irritating to the eyes, mucous
membranes, and upper respiratory tract.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
Absorption into the body leads to the formation of methemoglobin
which in sufficient concentration causes cyanosis. Onset may be
delayed 2 to 4 hours or longer. Symptoms of exposure may include
burning sensation, coughing, wheezing, laryngitis, shortness of
breath, headache, nausea, and vomiting.
IRRITATION DATA
Skin
Rabbit
4H
Remarks: No irritation effect
Eyes
Rabbit
Remarks: Moderate irritation effect
Section 12 - Ecological Information
ACUTE ECOTOXICITY TESTS
Test Type: EC50 Algae
Time: 96 h
Value: 44 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 0.2 mg/l
Test Type: LC50 Fish
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 100 mg/l
Test Type: LC50 Fish
Time: 48 h
Value: 55 mg/l
ELIMINATION
Elimination: > 90 %
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
This combustible material may be burned in a chemical incinerator
equipped with an afterburner and scrubber. Observe all federal,
state, and local environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: n-Methylaniline
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UN#: 2294
Class: 6.1
Packing Group: Packing Group III
Hazard Label: Toxic Substance
PIH: Not PIH
IATA
Proper Shipping Name: n-Methylaniline
IATA UN Number: 2294
Hazard Class: 6.1
Packing Group: III
Section 15 - Regulatory Information
EU DIRECTIVES CLASSIFICATION
Symbol of Danger: T-N
Indication of Danger: Toxic. Dangerous for the environment.
R: 23/24/25-33-50/53
Risk Statements: Toxic by inhalation, in contact with skin and
if swallowed. Danger of cumulative effects. Very toxic to
aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
S: 28-36/37-45-60-61
Safety Statements: After contact with skin, wash immediately
with plenty of soap-suds. Wear suitable protective clothing and
gloves. In case of accident or if you feel unwell, seek medical
advice immediately (show the label where possible). This
material and its container must be disposed of as hazardous
waste. Avoid release to the environment. Refer to special
instructions/safety data sheets.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Toxic.
Risk Statements: Toxic by inhalation, in contact with skin and
if swallowed. Irritating to eyes, respiratory system and skin.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. In
case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible). Wear suitable
protective clothing, gloves, and eye/face protection.
US Statements: Combustible. Readily absorbed through skin.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
ALDRICH - 236233 www.sigma-aldrich.com Page 5
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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