MATERIAL SAFETY DATA SHEET DIXIE CHEMICAL COMPANY, INC.
P.O. Box 130410
Houston, TX 77219-0410
(713) 863-1947
FAX: (713) 863-8316
SECTION 1 ?CHEMICAL IDENTIFICATION
Trade Name: Dimethylaniline Date of Issue: August 13, 2004
Synonyms: DMA; Revised Date: July 26, 2006
N,N-Dimethylaniline;
N,N-dimethylbenzeneamine;
Dimethylphenylamine;
Dimethylaminobenzene
Formula: C8H11N
Chemical Family: Amine
Chemical Use: Chemical intermediate
Telephone Number: Information (281) 474-3271
Emergency Number: Chemtrec (800) 424-9300 Domestic
(703) 527-3887 International
HMIS Hazard Rating
Health: 3* 4 = Extreme
Fire: 2 3 = High
Reactivity: 0 2 = Moderate
*-Chronic effect indicator. See Section 11. 1 = Slight
PPE rating to be supplied by user 0 = Least
depending on use conditions.
SECTION 2 ?HAZARDS IDENTIFICATION
Inhalation: May cause irritation to the nose, throat, and respiratory tract. May depress the
central nervous system and decrease the ability of the blood to carry oxygen.
Reacts with blood hemoglobin to form methemoglobin, which does not participate
in oxygen transport. Sufficient concentrations of methemoglobin in the blood can
result in suffocation in the presence of oxygen. Methemoglobinemia causes a blue
coloration of the lips, nail beds, and eyelids (cyanosis). Exposure may cause
headache, dizziness, weakness, fast labored breathing, increased pulse, lack of
energy, loss of coordination, cardiac arrest, convulsions, coma, and possibly death.
Skin Contact: May cause irritation. May be rapidly absorbed through the skin resulting in central
nervous system depression and hypoxia (cyanosis).
Eye Contact: May cause irritation. May be rapidly absorbed through the mucous membranes
resulting in central nervous system depression and hypoxia (cyanosis).
Ingestion: Will cause central nervous system depression and hypoxia (cyanosis).
Dimethylaniline (DMA), Page 2 of 8
SECTION 3 ?COMPOSITION
Components Percentage TLV (ppm) CAS #
N,N-Dimethylaniline >99 2 121-69-7
N-Methylaniline 0.45 0.5 100-61-8
Aniline 0.05 2 62-53-3
SECTION 4 ?FIRST AID MEASURES
Inhalation: Remove victim to fresh air. Get medical attention. If breathing is difficult, give
oxygen. If not breathing, administer artificial respiration.
Skin Contact: Immediately remove contaminated clothing and shoes. Wipe excess material from
skin and flush with water for at least 15 minutes. Use soap if available or follow by
washing with soap and water. Get medical attention.
Eye Contact: Immediately flush with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower lids. Get medical attention.
Ingestion: IMMEDIATELY INDUCE VOMITING IF VICTIM IS CONSCIOUS.
GET MEDICAL ATTENTION.
Note to Physician: Blood methemoglobin if exposure or degree of cyanosis is in
doubt. Avoid aspirin or aspirin-like precuts from complaints of headache. Advise
patient to avoid alcohol for 2 to 3 days. Symptoms from skin may be delayed.
Methemoglobinemia may require treatment with methylene blue. Exchange
transfusion may be required in severe or unresponsive cases.
SECTION 5 ?FIREFIGHTING MEASURES
Extinguishing Media: Use water, foam, dry chemical, or carbon dioxide (CO2). Use water in flooding
quantities to fight fire.
Special Firefighting Firefighters should wear NIOSH approved self-contained breathing apparatus.
Procedures/Precautions: Responders should wear protective clothing to prevent skin contact. Move
containers from fire area. If unable to move, cool sealed containers with water.
Unusual Fire and Toxic vapors such as oxides of carbon and nitrogen. Possibly nitriles, aromatic
Explosion Information: amines, aldehydes, acids, cyanide, and phenols.
Environmental Note: Prevent entry into waterways or sewers.
SECTION 6 ?ACCIDENTAL RELEASE MEASURES
Protective Measures: Evacuate area of unprotected personnel. Eliminate sources of ignition. Stay
upwind and out of low areas. Wear personal protective equipment (See section 8) when responding to
spills.
Dimethylaniline (DMA), Page 3 of 8
Spill Management: Stop source of leak if safe to do so. Dike and contain spill. Use water spray
(fog) to reduce vapors. If vapor cloud forms, blanket area with water fog and foam. Use vacuum truck
or pump to storage/salvage vessels. Clean up residue with an absorbent such as clay, sand or other
suitable material and dispose of properly. Spray area with water to remove trace residue. Contain run-
off from residue flush and dispose of properly. Prevent entry into waterways, sewer, or confined areas.
Remove contaminated trace residues from soil and dispose of in same manner as material. For small
spills, clean up residue with an absorbent such as clay, sand or other suitable material. Place in non-
leaking container and dispose of material properly.
Disposal: Proper disposal should be evaluated based on regulatory status of this material (refer to
section 13).
SECTION 7 ?HANDLING AND STORAGE
Containers do not have to be grounded and bonded when material is transferred, but it is recommended
as a good practice. Store in a cool, dry place. Keep away from heat, sparks, and flames.
SECTION 8 ?EXPOSURE CONTROLS AND PERSONAL PROTECTION
Respiratory Protection: NIOSH approved respiratory protection for organic vapors.
Ventilation: Utilize local exhaust to control high vapor connections in confined areas.
Protective Gloves: Utilize appropriate impervious chemical gloves.
Eye Protection: Chemical goggles and possibly a face shield. Have eyewash facilities readily
available.
Other Protective Wear additional protective clothing to prevent skin contact. This may include
Equipment: chemical resistant boots and chemical resistant suits.
Work Practices: Use good personal hygiene practices. Wash hands before eating, drinking,
smoking or using toilet facilities. Promptly remove soiled clothing and wash
thoroughly before reuse. Shower after work using plenty of soap and water.
SECTION 9 ?PHYSICAL AND CHEMICAL PROPERTIES
380-382癋 (193.5-194.5oC)
Boiling Point:
63癋 (2.1oC)
Melting Point:
Molecular Weight: 121.18
Volatility/Vol (%): Not Established
1 mm Hg at 86癋 (30oC); 10 mm Hg at 158癋 (70oC)
Vapor Pressure (mm Hg):
Vapor Density (Air = 1): 4.2
0.18%; 1.2 g/L at 68癋 (20oC) (Insoluble)
Solubility in H2O (%):
Appearance/Odor: Pale-yellow oily liquid (turns brown on exposure to air) /
Amine-like odor.
Odor Threshold 0.013 ppm
Viscosity (cps): Not Established
0.96 at 39癋 (4oC)
Specific Gravity (H2O = 1):
Dimethylaniline (DMA), Page 4 of 8
pH: Not Established
Log Octanol / Water Partition Coefficient: 2.31
Evap. Rate (Butyl Acetate = 1): Not Established
145oF (63oC) PMCC, ASTM D93
Flash Point:
Lower Explosive Limit: 1%
Upper Explosive Limit: 7%
698oF (370oC)
Autoignition Temperature
SECTION 10 ?STABILITY AND REACTIVITY
Chemical Stability: Stable at ambient temperatures; may darken slowly with age. Unstable at
elevated temperatures. Oxidizes slowly in air. Forms tarry residues after
prolonged heating and distillation.
Conditions to Avoid: Sources of ignition and incompatibles.
Incompatible Materials: Benzoyl peroxide, diisopropyl peroxydicarbonate , acids, oxidizing
agents, and aldehydes in acidic media.
Decomposition Products: Toxic vapors such as oxides of carbon and nitrogen. Possibly nitriles,
aromatic amines, aldehydes, acids, cyanide, and phenols.
Hazardous Polymerization: Will not occur at ambient temperatures.
SECTION 11 ?TOXICOLOGICAL INFORMATION
N,N-Dimethylaniline TLV: 2 ppm (Skin) STEL: 10 ppm
ACGIH
N-Methylaniline TLV: 0.5 ppm (Skin) STEL: Not Established
Aniline TLV: 2 ppm (Skin) STEL: Not Established
N,N-Dimethylaniline PEL: 5 ppm (Skin) STEL: Not Established
OSHA
N-Methylaniline PEL: 2 ppm (Skin) STEL: Not Established
Aniline PEL: 5 ppm (Skin) STEL: Not Established
N,N-Dimethylaniline IDLH 100 ppm
NIOSH
N-Methylaniline IDLH 100 ppm
Aniline IDLH 100 ppm
Carcinogenicity listed by: NTP: Yes IARC: Yes OSHA: No
Long-term animal experiments have shown to affect the liver, spleen, kidneys, and blood. Teratogenic
effects have also been shown.
Target Organs: Blood, liver, kidneys, cardiovascular system, and central nervous system.
Inhalation: N,N-Dimethylaniline
LCLo: 250 mg/m3 /4 Hours (rat)
Aniline
LCLo: 250 ppm / 4 Hours (rat)
TCLo: 10000 mg/m3: Eye effects, Pulmonary effects (human)
Skin: N,N-Dimethylaniline
Dimethylaniline (DMA), Page 5 of 8
LD50: 1770 mg/kg (adult rabbit)
500 mg / 24 Hours Moderate (adult rabbit)
Aniline
LD50: 1400 mg/kg (adult rabbit)
500 mg / 24 Hours Moderate (adult rabbit)
Eyes: Aniline
102 mg Severe (adult rabbit)
Ingestion: N,N-Dimethylaniline
LDLo: 50 mg/kg (human)
LD50: 1410 mg/kg (rat)
N-Methylaniline
LDLo: 280 mg/kg (adult rabbit)
Aniline
LD50: 250 mg/kg (rat)
SECTION 12 ?ECOLOGICAL INFORMATION
Terrestrial Fate: N,N-Dimethylaniline is expected to have moderate mobility in soil.
Aquatic Fate: N,N-Dimethylaniline is expected to adsorb slightly to sediment and suspended solids
in water.
Atmospheric Fate: N,N-Dimethylaniline is expected to exist solely as a vapor in the ambient
atmosphere.
Ecotoxicity: N,N-Dimethylaniline
LC50 Pimephales promelas (fathead minnow) 78.2 mg/l/96 hr (confidence limit: 74.2-
82.4 mg/l),flow-through bioassay measure concentrations, 23.4 oC, dissolved oxygen
7.0 mg/l), hardness 43.5 mg/l calcium carbonate, alkalinity 43.4 mg/l calcium
carbonate, and pH 7.38.
Aniline
LC50 Pimephales promelas (fathead minnow) 33 days old 134 mg/l/96 hr (95%
confidence limit: 122-148 mg/l), sample purity 99+%, temp 26.1 C, pH 7.58 hardness
47 mg of CaCO3/l. /Conditions of bioassay not specified.
SECTION 13 ?DISPOSAL INFORMATION
Place in a city, state, or federally permitted disposal facility. Handle in accordance with all applicable
hazardous waste regulations.
RCRA Waste Number U012 (Aniline)
SECTION 14 ?TRANSPORTATION INFORMATION
Proper Shipping Name: N,N-Dimethylaniline
Primary Hazard Class: 6.1
Secondary Hazard Class: None
Dimethylaniline (DMA), Page 6 of 8
Identification Number: UN 2253
Packing Group: II
Reportable Quantity: 100 pounds
Marine Pollutant: No
Label(s) Required: TOXIC
SECTION 15 ?REGULATORY INFORMATION
All substances are listed on, or are exempt from reporting.
TSCA:
TSCA 12(b) Export Notification: Not Listed
States Listings:
California Proposition 65:Aniline is known by the State of California to cause cancer.
Illinois Right-to-Know
Massachusetts Right-to-Know
Minnesota Right-to-Know
New Jersey Right-to-Know
New York State List of Hazardous Substances
Pennsylvania Right-to-Know
Rhode Island Right-to-Know
SARA Hazard Notification:
Hazard Categories Under Title III: Acute, Chronic, Fire.
Section 302 Extremely Hazardous Substances: 1000 pounds TPQ (Aniline)
Section 313 Toxic Chemicals: Aniline
CERCLA RQ: 100 pounds (N,N-Dimethylaniline).
European Regulations:
EINECS Number: N,N-dimethylaniline: 204-493-5
EC-No. 612-016-00-0
Labeling according to EC directives.
Symbol: T, N
Toxic, Dangerous For The Environment
R-Phrases: R23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
R40 Limited evidence of a carcinogenic effect.
R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.
S-Phrases: S1/2 Keep locked up and out of the reach of children.
S28 After contact with skin, wash immediately with plenty of . . . (to be specified by
Dimethylaniline (DMA), Page 7 of 8
the manufacturer)
S36/37 Wear suitable protective clothing and gloves.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show
the label where possible).
S61 Avoid release to the environment. Refer to special instructions/Safety data
sheets.
German Water Hazard Classification (WGK) Number: 2.
Canadian Regulations:
Listed on the DSL.
WHMIS Ingredient List
This product has been classified in accordance with the hazard criteria of the Controlled Products
Regulations and MSDS contains all the information required by the Controlled Products Regulations.
Japanese Regulations:
ENCS Number: 3-114X
Australian Regulations:
Listed on the AICS.
Korean Regulations:
ECL Number. KE-05-0532
Philippines Regulations:
Listed on the PICCS.
Swiss Regulations:
Listed on the Giftliste 1.
SWISS Number: G-1557
Toxic Category 2.
Taiwan Regulations:
Not Listed
SECTION 16 ?OTHER INFORMATION
PPE Codes (NPCA-HMIS)
A ?Glasses G ?Glasses, Gloves, Vapor Respirator
B ?Glasses, Gloves H ?Goggles, Gloves, Apron, Vapor Respirator
C ?Glasses, Gloves, Apron I ?Glasses, Gloves, Dust/Vapor Respirator
D ?Faceshield, Gloves, Apron J ?Goggles, Gloves, Apron, Dust/Vapor Respirator
E ?Glasses, Gloves, Dustmask K ?Supplied Air, Gloves, Full Protective Suit, Boots
Dimethylaniline (DMA), Page 8 of 8
F ?Glasses, Gloves, Apron, Dust Respirator
Disclaimer
The information contained in the Material Safety Data Sheet is based on technical data that Dixie Chemical
Company believes to be reliable and is provided to our customers at no cost. It is intended for use by persons
having technical skill and at their own discretion and risk. Dixie Chemical Company will assume no liability
in connection with any uses of this information and no warranties, expressed or implied, are made with
regards to this information since conditions of use are outside Dixie Chemical Company's control.
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