MATERIAL SAFETY DATA SHEET PHENYLHYDRAZINE
PRODUCT CODE NUMBER(S): 5870-5
Chemical Name and Synonyms: Phenylhydrazine heavier than air and can spread readily, and collect in low or
confined areas, creating a fire and toxicity hazard.
Chemical Family: Phenyl substituted hydrazine
Extinguishing Media: Carbon dioxide, dry chemical pow-
Chemical Formula: C6H8N2
der, alcohol or polymer foam. Water spray or fog may be
Product Use: Laboratory reagent used to disperse mist and fumes and cool containers, but
Manufacturer's Name and Address: may not be effect ive for extinguishing fire, and should not
be allowed to contact the chemical or get into the containers.
Caledon Laboratories Ltd.
Fight fire from upwind, from a safe distance. Firefighters
40 Armstrong Avenue
must wear protective equipment and clothing sufficient to
Georgetown, Ontario L7G 4R9
prevent inhalation of fumes and contact with skin and eyes.
Telephone No: (905) 877-0101 Closed containers may rupture violently during fire; withdraw
Fax No: (905) 877-6666 immediately in case of rising sound from vent or discolor-
ation of tank.
Emergency Telephone No: CANUTEC (613) 996-6666
Flash Point (Method Used): 88癈
HAZARDOUS INGREDIENTS OF MATERIALS Autoignition Temperature: 174癈
Upper Flammable Limit (% by volume): Not available
Ingredients % TLV Units CAS No.
Lower Flammable Limit (% by volume): Not available
Phenylhydrazine >95 0.1 ppm 100-63-0 Hazardous Combustion Products: COx, NOx
skin contact can contribute to overall exposure
Sensitivity to Impact: None identified
Sensitivity to Static discharge: Mist/air mixtures can
PHYSICAL DATA
probably explode if in contact with an electrostatic spark or
Physical State: Liquid other ignition source.
Odur and Appearance: Colourless, oily liquid, turns yellow
TOXICOLOGICAL PROPERTIES AND HEALTH DATA
to dark red on exposure to air and light; faint aromatic odour
Odour Threshold (ppm): Not available
Toxicological Data:
Vapour Pressure (mm Hg): 0.04 mm Hg @ 20癈
LD50: (oral, rat) 188 mg/kg; (oral, rabbit) 80 mg/kg
Vapour Density (Air = 1): 3.70
LC50: (rat) 2,610 mg/m3
Evaporation Rate: Not available
Boiling Point (degrees C): 243癈
Effects of Acute Exposure to Product:
Melting Point (degrees C): 19.5癈
Toxic by all routes of exposure. Causes hemolytic anemia
pH: 9.1 (0.1M)
(breakdown of red blood cells), causing anemia, weakness,
Specific Gravity: 1.1 @ 20癈
fainting, damage to kidneys, liver, spleen, bone marrow. Can
Coefficient of Water/Oil distribution: LogP (oct) = 1.25 be fatal by inhalation, ingestion, skin exposure.
Inhaled: Highly toxic, corrosive. Causes sore throat, cough-
SHIPPING DESCRIPTION ing, laboured breathing, and systemic symptoms such as
dizziness, weakness, fainting, jaundice (see above). Acute
UN: 2572
exposure to low concentrations of hydrazines may cause
T.D.G. Class: 6.1
bronchial mucous destruction, chemical pneumonitis and
Pkg. Group: II pulmonary edema, with cyanosis, shortness of breath, frothy
sputum, even death.
REACTIVITY DATA In contact with skin: Highly toxic, corrosive. Causes se-
vere irritation, redness, blistering. Severity of effects
Chemical Stability: Stable under normal conditions of use
depends on degree and duration of exposure. Readily ab-
and storage.
sorbed through skin causing hemolytic anemia, damage to
Incompatibility with other substances: Avoid strong oxi- liver, kidneys. Can cause contact dermatitis, and skin sensi-
dizers, lead dioxide. Corrosive to steel, cast iron, nickel. tization.
Reactivity: Avoid excessive heat, ignition sources, incom- In contact with eyes: Highly toxic, corrosive. Causes se-
patible materials, exposure to light and air, generation of vere irritation and potential permanent damage to the eyes.
dust or fumes.
Ingested: Highly toxic, corrosive. Causes gastrointestinal
Hazardous Decomposition Products: COx, NOx irritation, with nausea, vomiting, abdominal pain, and sys-
temic symptoms such as laboured breathing, dizziness,
FIRE AND EXPLOSION DATA bluish skin, weakness, fainting, jaundice.
Flammability: Combustible liquid and vapour. Can form
explosive mixtures with air at, or above, 88癈. Vapours are
PHENYLHYDRAZINE
MSDS
CODE: 5870-5
Effects of Chronic Exposure to Product: mists or vapours. Wash thoroughly after handling. Empty
containers may contain hazardous residues; treat with ex-
Persons with pre-existing skin disorders, eye problems, or treme caution.
impaired liver or kidney function, may be more susceptible
Storage Requirements: Store in suitable, labelled contain-
to the effects of this substance. ers, in a cool, dry, well-ventilated area, out of direct sunlight,
and away from all ignition sources, and incompatible or
Prolonged or repeated skin contact may cause dermatitis.
comubstible materials. Keep containers tightly closed when
Prolonged or repeated eye contact may cause conjunctivitis.
not in use and when empty. Protect from damage. Inspect
Chronic inhalation and ingestion may cause liver, kidney,
frequently for signs of damamge or leaking.
spleen and bone marrow effects as in "Effects of Acute Ex-
posure . . .". May cause methemoglobinemia, with blood
FIRST AID MEASURES
and central nervous system effects, kidney damage, ane-
mia, reticulocytosis, hematuria, weakness, depression, re-
Specific Measures:
spiratory distress, irregular heart rate, eventual coma and
Eyes: Flush thoroughly with gently running water for at
death.
least fifteen (15) minutes, holding eyelids open while flush-
Carcinogenicity: Carcinogenicity designation A3 (ACGIH),
ing. Take care not to flush contaminated water into
confirmed animal carcinogen, unknown relevance to hu-
unaffected eye. Wear protective gloves during first aid pro-
mans.
cedures to avoid contact with this chemical. GET MEDICAL
Teratogenicity: Has produced behavioral effects in testing
ATTENTION IMMEDIATELY.
with laboratory animals.
Skin: Remove contaminated clothing (including shoes,
Reproductive Effects: Has produced effects in animal
watches, belts, and rings). Flush skin with plenty of running
testing.
water for at least fifteen (15) minutes. Wear protective
Mutagenicity: Has produced effects in laboratory testing gloves during first aid procedures to avoid contact with this
Synergistic Products: None known chemical. GET MEDICAL ATTENTION IMMEDIATELY. De-
contaminate cltohing before reuse, or discard.
PREVENTIVE MEASURES Inhalation: Remove to fresh air. Give oxygen for any
breathing difficulty. If any symptoms of hemolytic anemia
Engineering Controls: Local corrosion-resistant exhaust
are present (dizziness, drowsiness, headache, shortness of
ventilation required.
breath, cyanosis, irregular heartbeat, headache, nausea
Respiratory Protection: Dust mask, fumehood. For any and vomiting), get medical attention, and monitor condition
detectable concentration, or for unknown concentrations, as for several hours. If breathing has stopped give artificial res-
in fire or spill conditions, NIOSH approved positive-pressure, piration and GET MEDICAL ATTENTION IMMEDIATELY.
full face-piece self-contained breathing apparatus, or full
Ingestion: If victim is alert and not convulsing, give 1 to 2
face-piece supplied-air respirator with auxiliary posi-
glasses of water to dilute material. DO NOT INDUCE
tive-pressure self-contained breathing apparatus.
VOMITING. If spontaneous vomiting occurs, have victim
Eye Protection: Chemical safety goggles and/or lean forward with head down to avoid breathing in of
face-shield. vomitus, rinse mouth and administer more water. Get medi-
Skin Protection: Impervious rubber or neoprene gloves. cal attention IMMEDIATELY.
Impervious labcoat, apron, sleeves and boots sufficient to
REFERENCES USED
prevent any contact.
Other Personal Protective Equipment: Safety shower
CCINFO disc: Cheminfo
and eye-wash fountain in work area.
Budavari: The Merck Index, 12th ed., 1997
Leak and Spill Procedure: Evacuate area of spill.
Cleanup personnel must be thoroughly trained in the han- Sax, Lewis: Hawley's Condensed Chemical Dictionary, 11th
dling of hazardous materials, and must wear protective ed., 1987
equipment and clothing sufficient to prevent inhalation of
Suppliers' Material Safety Data Sheets
dusts or fumes and contact with skin and eyes. Eliminate all
ignition sources. Use non-sparking tools and equipment.
ADDITIONAL INFORMATION
Do not touch spilled material. Mix with sand, or other inert
material, transfer carefully into container and arrange re- Date Issued: March 30, 1999
moval by disposal company. Wash site of spillage
Revision: March 2008
thoroughly with copious amounts of water and detergent.
MSDS: 5870-5
Waste Disposal: Follow all federal, provincial and local
Proposed WHMIS Designation: B3; D1A; D2A
regulations for disposal.
Handling Procedures and Equipment: TOXIC, CORRO-
SIVE. Workers using this mateiral must be thoroughly Prepared by: Caledon Laboratories Ltd. (905) 877-0101
trained in its hazards and its safe use, and must wear appro- Caledon Laboratories Ltd. believes the information contained
priate protective equipment and clothing. Follow routine herein is reliable and accurate. Caledon makes no warranty
safe handling procedures and good housekeeping proce- with respect thereto and expressly disclaims all liability for reli-
dures; keep work area free of extraneous, paricularly ance thereon. Such information is solely for your consider-
combustible, materials. Avoid generating mist. If mist is
ation, investigation, and verification.
present, keep away from heat, sparks, and all sources of ig-
nition; avoid the accumulation of static charge, use
anti-sparking tools and ground and bond equipment and
containers. Use the smallest amount possible for the pur-
pose, in designated areas with adequate ventilation. Avoid
all contact with skin, eyes, and clothing and inhalation of
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