MATERIAL SAFETY DATA SHEET
Thionex?3EC
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1. PRODUCT AND COMPANY INDENTIFICATION
THIONEX ?3EC
Product name:
Chemical name of active ingredient(s): Endosulfan:Hexachlorohexahydromethano-
2,4,3-benzodioxathiepin oxide
Registrant:/Manufacturer: Makhteshim-Agan of North America
551 Fifth Avenue, Suite 1100
New York, NY 10176
Phone: 1-212-661-9800
For fire, spill, and/or leak emergencies, contact Phone: 1-800-535-5053
Infotrac:
For medical emergencies and health and Phone: 1-877-250-9291
safety inquiries, contact Prosar:
2. COMPOSITION/INFORMATION ON INGREDIENTS
CHEMICAL CAS# Wt.% PEL/TLV EC No. EC CLASS
NAME
3
Endosulfan 115-29-7 33.7 0.1 mg.m 602-052-00-5 R24/25-36
ACGIH TWA
Aromatic 64742-95- <37 100 ppm 650-001-00-0 None
Hydrocarbons 6 (supplier)
1,2,4- 95-63-6 <19 25 ppm ACGIH None None
trimethylbenzene TWA
Surfactant Blend 0000-00-0 <3.4 None None None
Xylene 1330-20-7 <1.8 100 ppm 601-022-00-9 R11-20/21-38
Cumene 98-82-8 <1.2 50 ppm OSHA 601-024-00-X R10-37
PEL & ACGIH
Ethylbenzene 100-41-4 <0.6 100 ppm OSHA 601-023-00-4 R11-20
PEL
125 ppm
ACGIH TLV
1-butanol 71-36-3 <0.3 100 ppm OSHA 603-004-00-6 R10-20
PEL
50 ppm ACGIH
(ceiling)
3. HAZARDS INDENTIFICATION
EMERGENCY OVERVIEW
IMMEDIATE CONCERNS:
? Amber liquid with an aromatic hydrocarbon odor.
? Moderately combustible. May support combustion if heated above the product's flash
point (see Section 5, "Fire Fighting Measures" below).
? Thermal decomposition and burning may form toxic by-products.
? For large exposures or fire, wear personal protective equipment.
? Highly toxic to fish and aquatic organisms. Keep out of drains and water courses.
? Highly toxic if swallowed, inhaled, or absorbed through the skin.
? Moderately irritating to the eyes and skin.
POTENTIAL HEALTH EFFECTS: Effects from overexposure result from either swallowing,
inhaling, or absorption through the skin. Symptoms of overexposure include convulsions,
tremors, decreased locomotion, and oral discharge.
MEDICAL CONDITIONS AGGRAVATED: None presently known.
4. FIRST AID MEASURES
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MATERIAL SAFETY DATA SHEET
Thionex?3EC
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EYES: Flush with water for at least 15 minutes. If irritation occurs and persists, contact a medical
doctor.
SKIN: Remove contaminated clothing and thoroughly wash with soap and water. If irritation
occurs and persists, contact a medical doctor.
INGESTION: Rinse mouth with water. Dilute by giving 1 or 2 glasses of water. Do not induce
vomiting. Never give anything by mouth to an unconscious person. See a medical doctor
immediately.
INHALATION: Remove to fresh air. If breathing difficulty or discomfort occurs and persists, see a
medical doctor. If breathing has stopped, give artificial respiration and see a medical doctor
immediately.
NOTES TO MEDICAL DOCTOR: This product is highly toxic if swallowed, inhaled, or absorbed
thorough the skin. It is moderately irritating to the eyes and skin. Endosulfan is a central nervous
system stimulant absorbable through oral, inhalation, or dermal routes. It may cause
convulsions. Central nervous system stimulation can be controlled with diazepam (i.v.) or
barbituric acid derivatives. Epinephrine is contraindicated due to cardiac muscle stimulation.
This product contains light aromatic hydrocarbons that can produce a severe pneumonitis or fatal
pulmonary edema if aspirated during vomiting. Consideration should be given to gastric lavage
with an endotracheal tube in place. Treatment is otherwise controlled removal of exposure
followed by symptomatic and supportive care.
5. FIRE FIGHTING MEASURES
FLASH POINT AND METHOD: 40癈 (104癋) (TCC)
EXTINGUISHING MEDIA: Foam, CO2 or dry chemical. Soft stream water fog only if necessary.
Contain all runoff.
FIRE/EXPLOSION HAZARDS: Moderately combustible. When heated above the flash point, this
material releases vapors which, when mixed with air, can burn or be explosive.
FIRE FIGHTING PROCEDURES: Isolate fire area. Evacuate downwind. Wear full protective
clothing and self-contained breathing apparatus. Do not breathe smoke, gases, or vapors
generated.
HAZARDOUS DECOMPOSITION PRODUCTS: Carbon monoxide, carbon dioxide, hydrogen
chloride, and oxides of sulfur.
6. ACCIDENTAL RELEASE MEASURES
RELEASE NOTES: Isolate and post spill area. Wear protective clothing and personal protective
equipment as prescribed in Section 8, "Exposure Controls/Personal Protection". Keep
unprotected persons and animals out of the area.
Keep material out of lakes, streams, ponds, and sewer drains. Dike to confine spill and absorb
with a non-combustible absorbent such as clay, sand, or soil. Vacuum, shovel, or pump waste
into a drum and label contents for disposal.
To clean and neutralize spill area, tools, and equipment, wash with a suitable solution of caustic
or soda ash, and an appropriate alcohol (i.e. methanol, ethanol, or isopropanol). Follow this by
washing with a strong soap and water solution. Absorb, as above, any excess liquid and add to
the drums of waste already collected. Repeat if necessary. Dispose of drummed waste
according to the method outlined in Section 13, "Disposal Considerations".
7. HANDLING AND STORAGE
GENERAL PROCEDURES: Store in a cool, dry, well ventilated place. Do not use or store near
heat, open flame, or hot surfaces. Keep out of reach of children and animals. Store in original
containers only. Carefully open containers. After partial use, replace lid and close tightly. Do not
contaminate other pesticides, fertilizers, water, food, or feed by storage or disposal.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
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MATERIAL SAFETY DATA SHEET
Thionex?3EC
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ENGINEERING CONTROLS: Use local exhaust at all process locations where vapor or mist may
be emitted. Ventilate all transport vehicles prior to unloading.
PERSONAL PROTECTIVE EQUIPMENT
EYES AND FACE: For splash, mist, or spray exposure, wear chemical protective goggles or a
face shield.
RESPIRATORY: For splash, mist, or spray exposure wear, as a minimum, a properly fitted half-
face or full-face air-purifying respirator which is approved for pesticides (U.S. NIOSH/MSHA, EU
CEN, or comparable certification organization). Respirator use and selection must be based on
airborne concentrations.
PROTECTIVE CLOTHING: Depending upon concentrations encountered, wear coveralls or long-
sleeved uniform and head covering. For larger exposures as in the case of spills, wear full body
cover barrier suit, such as a PVC suit. Leather items 璼uch as shoes, belts and watchbands-that
become contaminated should be removed and destroyed. Launder all work clothing before reuse
(separately from household laundry).
WORK HYGENIC PRACTICES: Clean water should be available for washing in case of eye or
skin contamination. Wash skin prior to eating, drinking, or using tobacco. Shower at the end of
the workday.
GLOVES: Wear chemical protective gloves made of materials such as nitrile or Viton?brand.
Thoroughly wash the outside of gloves with soap and water prior to removal. Inspect regularly for
leaks.
9. PHYSICAL AND CHEMICAL PROPERTIES
ODOR: Aromatic hydrocarbon
APPEARANCE: Amber Liquid
SOLUBILITY IN WATER: Emulsifies
SPECIFIC GRAVITY: 1.06@20癈 (water=1)
MOLECULAR WEIGHT: 406.95(endosulfan)
MOLECULAR FORMULA: C9 H6CI6O2S (endosulfan)
WEIGHT PER VOLUME: 8.82 lb/gal. (1060 g/L)
10. STABILITY AND REACTIVITY
CONDITIONS TO AVOID: Excessive heat and fire.
STABILITY: Stable
POLYMERIZATION: Will not occur
11. TOXICOLOGICAL INFORM ATION
DERMAL LD50: 256 mg/kg (rabbit)
ORAL LD50: 44.9 mg/kg (rat)
INHALATION LC50: 22 mg/L/4 hr. (rat)
ACUTE EFFECTS FROM OVEREXPOSURE: This product is highly toxic if swallowed, inhaled,
or absorbed through the skin. It is moderately irritating to the eyes and skin. Signs of toxicity in
laboratory animals included tremors, clonic convulsions, decreased locomotion,
chromorhinorrhea, and oral discharge. Inhalation of aromatic hydrocarbon vapors may cause
dizziness, disturbances in vision, drowsiness, respiratory irritation, and eye, skin, and mucous
membrane irritation. Vomiting after ingestion of this product may cause aspiration of aromatic
hydrocarbons into the lungs, which may result in fatal pulmonary edema. Exposure to butanol
vapors may produce headaches, drowsiness, and irritation of the nose and throat. Excessive
exposures to butanol liquid or vapors may result in contact dermatitis and irritation of the mucous
membranes.
CHRONIC EFFECTS FROM OVEREXPOSURE: No data available for the formulation. In
chronic studies with laboratory animals, endosulfan showed no evidence of carcinogenicity.
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Thionex?3EC
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Endosulfan caused toxic nephropathy in rat chronic feeding studies. In a two-generation
reproduction study with laboratory animals, endosulfan caused decreased litter weights at the
highest dose. Endosulfan was non-mutagenic in a battery of tests. Chronic exposure to aromatic
hydrocarbons may cause headaches, dizziness, loss of sensation or feelings (such as
numbness), and liver and kidney damage. Inhalation of xylene vapors at high doses has also
resulted in an increased incidence of malformations and decreases in fetal weight in laboratory
animals. Damage from xylene may be potentiated by alcohol. Disturbances in hearing and
balance have been reported in workers exposed to butanol vapors.
CARCINOGENICITY:
IARC: Ethylbenzene = 2B, Xylene = 3
NTP: Not listed
OSHA: Not listed
OTHER-(ACGIH): Not listed
12. ECOLOGICAL INFORMATION
Unless otherwise indicated, the data presented below are based on the active ingredient.
ENVIRONMENTAL DATA: In natural waters, endosulfan is more readily degraded at pH 7 (half-
life=5 weeks) than at pH 5.5 (half-life=5 months). The half-life in soils varies with soil type and
environmental conditions, with 120 days being average under agricultural conditions. The a- and
?isomers degrade at different rates, with the ?isomer being more persistent. Endosulfan has a
slight potential for movement in soils, however, the potential is decreased with increasing organic
matter content of the soil. The bioconcentration factor for endosulfan varies by species and
length of exposure but is generally less than 100.
ECOTOXICOLOGICAL INFORMATION: Endosulfan is considered highly toxic to fish with LC50
values of 1.0 to 10.0 礸/L. Crustaceans and mollusks are less sensitive with LC50 values of 10 to
1600 礸/L. Endosulfan is slightly toxic to birds and oral LD50 values range from 200 to 1000
mg/kg.
13. DISPOSAL CONSIDERATIONS
DISPOSAL METHOD: Open dumping or burning of this material or its packaging is prohibited. If
spilled material cannot be disposed of by use according to label instructions, an acceptable
method of disposal is to incinerate in accordance with local, state and national environmental
laws, rules, standards, and regulations. However, because acceptable methods of disposal may
vary by location and regulatory requirements may change, the appropriate agencies should be
contacted prior to disposal.
EMPTY CONTAINER: Non-returnable containers which held this material should be cleaned,
prior to disposal, by triple rinsing. Containers which held this material may be cleaned by being
triple-rinsed, and recycled, with the rinsate being incinerated. Do not cut or weld metal
containers. Vapors that form may create an explosion hazard.
14. TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION (DOT)
PROPER SHIPPING NAME: RQ, Organochlorine Pesticides, Liquid, Toxic, Flammable
(Endosulfan)
TECHNICAL NAME: Endosulfan
PRIMARY HAZARD CLASS/DIVISION: 6.1
SUBSIDIARY HAZARD CLASS/DIVISION: 3
UN/NA NUMBER: UN 2995
PACKING CROUP: II
REPORTABLE QUANTITY (RQ): Endosulfan (1#)
U.S. SURFACE FREIGHT CLASS: Item 45617 [Fungicides, Herbicides, Insecticides, or
Rodenticides], Class 77.5
MARINE POLLUTANT #1: Endosulfan (Severe Marine Pollutant)
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MATERIAL SAFETY DATA SHEET
Thionex?3EC
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NAERG: 131
15. REGULATORY INFORMATION
UNITED STATES
SARA TITLE III (SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT)
SECTION 302 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355): Endosulfan
SECTION 302.4 REPORTABLE QUANTITY (40 CFR 355): The following is a list of the
ingredients.
Chemical Name RQ
Endosulfan 1 lb.
SECTION 311 HAZARD CATEGORIES (40 CFR 370): Immediate, Delayed, Fire
SECTION 312 THRESHOLD PLANNING QUANTITY (40 CFR 370): The threshold planning
quantity (TPQ) for this product, if treated as a mixture, is 10,000 lbs. This product contains the
following ingredients with a TPQ of less than 10,000 lbs.: endosulfan (10 lbs.)
SECTION 313 REPORTABLE INGREDIENTS (40 CFR 372): This product contains the following
ingredients subject to Section 313 reporting requirements: (1,2,4-trimethylbenzene) (xylene,
mixed isomers) (cumene)
CERCLA (COMPREHENSIVE ENVIRONMENTAL RESPONSE COMPENSATION AND
LIABILITY ACT): Listed-
Chemical Name Wt.% RQ
Endosulfan 33.7 1 lb.
Xylene <1.8 100 lbs.
Cumene <1.2 5000 lbs.
Ethylbenzene <0.6 1000 lbs.
1-butanol <0.3 5000 lbs.
COMMENTS: Australian Hazard Code: 3XE
U.S. EPA Signal Word: DANGER-POISON
16. OTHER INFORMATION
MSDS issue date: 9-27-02
This document has been prepared to meet the requirements of the U.S. OSHA Hazard
Communication Standard, 29 CFR 1910.1200; the EC directive, 91/155/ECC and other regulatory
requirements. The information contained herein is for the concentrate as package, unless
otherwise noted.
The information contained herein is given in good faith and is believed to be correct, but no
warrant, express or implied, is made. Consult Makhteshim-Agan for further information.
Issued 9-27-02
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