KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 1 of 15
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
KITTEN GLO-WASH
SYNONYMS
Manufacturer's Code: 17210 car washing liquid
PRODUCT USE
Car washing liquid.
SUPPLIER
Company: CRC Industries (Aust) Pty Limited Company: CRC Industries (Aust) Pty Limited
Address: Address:
PO Box 199 9 Gladstone Rd
Castle Hill Castle Hill
NSW, 2154 NSW, 2154
AUS AUS
Telephone: (+61 2) 9634 2088
Company: CRC Industries New Zealand Ltd Fax: 02 9680 4914
Address:
PO Box 58-121 Company: CRC Industries New Zealand Ltd
Greenmount Address:
Auckland, 10 Waiouru Road
NZL East Tamaki
Telephone: +64 9 274 5710 Auckland,
Fax: +64 9 274 9696 NZL
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS.
According to the Criteria of NOHSC, and the ADG Code.
POISONS SCHEDULE
None
RISK
SAFETY
Do not breathe gas/fumes/vapour/spray.
Avoid contact with skin.
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 2 of 15
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
(C10-16)alkylbenzenesulfonic acid, sodium salt 68081-81-2 1-10
diethanolamine cocoate 8051-30-7 1-10
sodium sulfate 7757-82-6 0.1-1
diethanolamine 111-42-2 0.1-0.6
lauroylsarcosine, sodium salt 137-16-6 0.1-1
glycerol 56-81-5 0.1-1
EDTA tetrasodium salt 64-02-8 <0.1
brown dye <0.1
1,2-benzisothiazolin-3-one, sodium salt 58249-25-5 <0.01
water 7732-18-5 >60
Section 4 - FIRST AID MEASURES
SWALLOWED
鈥? Immediately give a glass of water.
鈥? First aid is not generally required. If in doubt, contact a Poisons
Information Centre or a doctor.
EYE
If this product comes in contact with eyes:
鈥? Wash out immediately with water.
鈥? If irritation continues, seek medical attention.
鈥? Removal of contact lenses after an eye injury should only be undertaken by
skilled personnel.
SKIN
If skin contact occurs:
鈥? Immediately remove all contaminated clothing, including footwear
鈥? Flush skin and hair with running water (and soap if available).
鈥? Seek medical attention in event of irritation.
INHALED
鈥? If fumes or combustion products are inhaled remove from contaminated area.
鈥? Other measures are usually unnecessary.
NOTES TO PHYSICIAN
Treat symptomatically.
Section 5 - FIRE FIGHTING MEASURES
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 3 of 15
Section 5 - FIRE FIGHTING MEASURES ...
EXTINGUISHING MEDIA
The product contains a substantial proportion of water, therefore there are no
restrictions on the type of extinguishing media which may be used. Choice of
extinguishing media should take into account surrounding areas.
Though the material is non-combustible, evaporation of water from the mixture,
caused by the heat of nearby fire, may produce floating layers of combustible
substances.
In such an event consider:
鈥? foam
鈥? dry chemical powder
鈥? carbon dioxide
FIRE FIGHTING
鈥? Alert Fire Brigade and tell them location and nature of hazard.
鈥? Wear breathing apparatus plus protective gloves for fire only.
鈥? Prevent, by any means available, spillage from entering drains or water
courses.
鈥? Use fire fighting procedures suitable for surrounding area.
鈥? DO NOT approach containers suspected to be hot.
鈥? Cool fire exposed containers with water spray from a protected location.
鈥? If safe to do so, remove containers from path of fire.
鈥? Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
The emulsion is not combustible under normal conditions. However, it will break
down under fire conditions and the hydrocarbon component will burn.
鈥? Non combustible.
鈥? Not considered to be a significant fire risk.
鈥? Expansion or decomposition on heating may lead to violent rupture of
containers.
鈥? Decomposes on heating and may produce toxic fumes of carbon monoxide (CO).
鈥? May emit acrid smoke.
Decomposition may produce toxic fumes of.
carbon dioxide (CO2).
hydrogen bromide.
nitrogen oxides (NOx).
phosphorus oxides (POx).
sulfur oxides (SOx).
metal oxides.
other pyrolysis products typical of burning organic material.
May emit poisonous fumes.
May emit corrosive fumes.
FIRE INCOMPATIBILITY
None known.
HAZCHEM
None
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 4 of 15
Section 5 - FIRE FIGHTING MEASURES ...
Personal Protective Equipment
PERSONAL PROTECTION EQUIPMENT
Gas tight chemical resistant suit.
Limit exposure duration to 1 BA set - 30 mins.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
鈥? Clean up all spills immediately.
鈥? Avoid breathing vapours and contact with skin and eyes.
鈥? Control personal contact by using protective equipment.
鈥? Contain and absorb spill with sand, earth, inert material or vermiculite.
鈥? Wipe up.
鈥? Place in a suitable labelled container for waste disposal.
MAJOR SPILLS
Moderate hazard.
鈥? Clear area of personnel and move upwind.
鈥? Alert Fire Brigade and tell them location and nature of hazard.
鈥? Wear breathing apparatus plus protective gloves.
鈥? Prevent, by any means available, spillage from entering drains or water
course.
鈥? Stop leak if safe to do so.
鈥? Contain spill with sand, earth or vermiculite.
鈥? Collect recoverable product into labelled containers for recycling.
鈥? Neutralise/decontaminate residue.
鈥? Collect solid residues and seal in labelled drums for disposal.
鈥? Wash area and prevent runoff into drains.
鈥? After clean up operations, decontaminate and launder all protective clothing
and equipment before storing and re-using.
鈥? If contamination of drains or waterways occurs, advise emergency services.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
鈥? Avoid all personal contact, including inhalation.
鈥? Wear protective clothing when risk of exposure occurs.
鈥? Use in a well-ventilated area.
鈥? Avoid contact with moisture.
鈥? Avoid contact with incompatible materials.
鈥? When handling, DO NOT eat, drink or smoke.
鈥? Keep containers securely sealed when not in use.
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 5 of 15
Section 7 - HANDLING AND STORAGE ...
鈥? Avoid physical damage to containers.
鈥? Always wash hands with soap and water after handling.
鈥? Work clothes should be laundered separately. Launder contaminated clothing
before re-use.
鈥? Use good occupational work practice.
鈥? Observe manufacturer's storing and handling recommendations.
鈥? Atmosphere should be regularly checked against established exposure standards
to ensure safe working conditions are maintained.
DO NOT allow clothing wet with material to stay in contact with skin
SUITABLE CONTAINER
鈥? Polyethylene or polypropylene container.
鈥? Packing as recommended by manufacturer
鈥? Check all containers are clearly labelled and free from leaks.
STORAGE INCOMPATIBILITY
None known
STORAGE REQUIREMENTS
鈥? Store in original containers.
鈥? Keep containers securely sealed.
鈥? Store in a cool, dry, well-ventilated area.
鈥? Store away from incompatible materials and foodstuff containers.
鈥? Protect containers against physical damage and check regularly for leaks.
鈥? Observe manufacturer's storing and handling recommendations.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
ODOUR SAFETY FACTOR (OSF)
OSF=1.7 (DIETHANOLAMINE)
Exposed individuals are NOT reasonably expected to be warned, by smell, that the
Exposure Standard is being exceeded.
Odour Safety Factor (OSF) is determined to fall into either Class C, D or E.
The Odour Safety Factor (OSF) is defined as:
OSF= Exposure Standard (TWA) ppm/ Odour Threshold Value (OTV) ppm
Classification into classes follows:
Class OSF Description
A 550 Over 90% of exposed
individuals are aware by
smell that the Exposure
Standard (TLV-TWA for
example) is being
reached, even when
distracted by working
activities
B 26-550 As "A" for 50-90% of
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 6 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
persons being distracted
C 1-26 As "A" for less than 50%
of persons being
distracted
D 0.18-1 10-50% of persons aware
of being tested perceive
by smell that the
Exposure Standard is
being reached
E <0.18 As "D" for less than 10%
of persons aware of being
tested
EXPOSURE STANDARDS FOR MIXTURE
"Worst Case" computer-aided prediction of vapour components/concentrations:
Composite Exposure Standard for Mixture (TWA) (mg/m鲁): 2 mg/m鲁
If the breathing zone concentration of ANY of the components listed below is
exceeded, "Worst Case" considerations deem the individual to be overexposed.
Component Breathing Zone ppm Breathing Zone mg/m鲁 Mixture Conc: (%)
Component Breathing zone Breathing Zone Mixture Conc
(ppm) (mg/m鲁) (%)
diethanolamine 0.46 2.0000 0.6
Operations which produce a spray/mist or fume/dust, introduce particulates to
the breathing zone.
If the breathing zone concentration of ANY of the components listed below is
exceeded, "Worst Case" considerations deem the individual to be overexposed.
At the "Composite Exposure Standard for Mixture" (TWA) (mg/m鲁): 0.6 mg/m鲁
Component Breathing Zone Concentration
(mg/m鲁) (%)
(C10-16)alkylbenzenesulfonic acid, 33.3333 10.0
sodium sulfate 3.3333 1.0
lauroylsarcosine, sodium salt 3.3333 1.0
glycerol 3.3333 1.0
EDTA tetrasodium salt 0.3333 0.1
1,2-benzisothiazolin-3-one, sodium 0.0000 0.0
INGREDIENT DATA
(C10-16)ALKYLBENZENESULFONIC ACID, SODIUM SALT:
TLV TWA: 10 mg/m鲁 (Value for particulate matter containing no asbestos and <1% crystalline
silica,Inhalable fraction) [ACGIH]
TLV TWA: 3 mg/m鲁 (Value for particulate matter containing no asbestos and <1% crystalline
silica,Respirable fraction) [ACGIH]
Dusts not otherwise classified, as inspirable dust;
ES TWA: 10 mg/m鲁.
Particulate (insoluble or poorly soluble *) Not Otherwise Specified (P.N.O.C)
TLV TWA: 10 mg/m鲁 Inhalable particulate
TLV TWA: 3 mg/m鲁 Respirable particulate
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 7 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
OEL-Sweden, United Kingdom: 10 mg/m鲁 total dust, 5 mg/m鲁 respirable dust
These "dusts" have little adverse effect on the lungs and do not produce toxic
effects or organic disease. Although there is no dust which does not evoke some
cellular response at sufficiently high concentrations, the cellular response
caused by P.N.O.C.s has the following characteristics:
路 the architecture of the air spaces remain intact,
路 scar tissue (collagen) is not synthesised to any degree,
路 tissue reaction is potentially reversible.
Extensive concentrations of P.N.O.C.s may:
路 seriously reduce visibility,
路 cause unpleasant deposits in the eyes, ears and nasal passages,
路 contribute to skin or mucous membrane injury by chemical or mechanical action,
per se, or by the rigorous skin cleansing procedures necessary for their
removal. [ACGIH]
This limit does not apply:
路 to brief exposures to higher concentrations
路 nor does it apply to those substances that may cause physiological impairment
at lower concentrations but for which a TLV has as yet to be determined.
This exposure standard applies to particles which
路 are insoluble or poorly soluble* in water or, preferably, in aqueous lung
fluid (if data is available) and
路 have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise
chemically reactive with lung tissue, and do not emit ionizing radiation, cause
immune sensitization, or cause toxic effects other than by inflammation or by a
mechanism of lung overload)
* Notice of intended change
For each of the following
DIETHANOLAMINE COCOATE:
WATER:
No exposure limits set by NOHSC or ACGIH
For each of the following
SODIUM SULFATE:
LAUROYLSARCOSINE, SODIUM SALT:
EDTA TETRASODIUM SALT:
1,2-BENZISOTHIAZOLIN-3-ONE, SODIUM SALT:
TLV TWA: 10 mg/m鲁 (Value for particulate matter containing no asbestos and <1% crystalline
silica,Inhalable fraction) [ACGIH]
TLV TWA: 3 mg/m鲁 (Value for particulate matter containing no asbestos and <1% crystalline
silica,Respirable fraction) [ACGIH]
Dusts not otherwise classified, as inspirable dust;
ES TWA: 10 mg/m鲁
DIETHANOLAMINE:
TLV TWA: 2 mg/m鲁 Skin [ACGIH]
TLV TWA: 0.46 ppm, 2 mg/m鲁 (skin)
ES TWA: 3 ppm, 15 mg/m鲁
OES TWA: 3 ppm, 13 mg/m鲁
Exposure limits with "skin" notation indicate that vapour and liquid may be
absorbed through intact skin. Absorption by skin may readily exceed vapour
inhalation exposure. Symptoms for skin absorption are the same as for
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 8 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
inhalation. Contact with eyes and mucous membranes may also contribute to
overall exposure and may also invalidate the exposure standard.
Odour Threshold: 2.6 ppm
The TLV-TWA is thought to be protective against the significant risk of
eye damage and skin irritation.
GLYCEROL:
TLV TWA: 10 mg/m鲁 [ACGIH]
TLV TWA: 10 mg/m鲁 (mist)
ES TWA: 10 mg/m鲁 (mist)
OES TWA: 10 mg/m鲁 (mist)
The mist is considered to be a nuisance particulate which appears to have
little adverse effect on the lung and does produce significant organic
disease or toxic effects. OSHA concluded that this limit would protect the
worker form kidney damage and perhaps, testicular effects.
PERSONAL PROTECTION
EYE
鈥? Safety glasses with side shields.
鈥? Chemical goggles.
鈥? Contact lenses pose a special hazard; soft lenses may absorb irritants and all
lenses concentrate them. DO NOT wear contact lenses.
HANDS/FEET
Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber.
NOTE: The material may produce skin sensitisation in predisposed individuals.
Care must be taken, when removing gloves and other protective equipment, to
avoid all possible skin contact.
OTHER
鈥? Overalls.
鈥? P.V.C. apron.
鈥? Barrier cream.
鈥? Skin cleansing cream.
鈥? Eye wash unit.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
"Forsberg Clothing Performance Index".
The effect(s) of the following substance(s) are taken into account in the
computer-generated selection:
Substance
________________________________________
water
glycerol
NATURAL RUBBER C
* CPI - Chemwatch Performance Index
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 9 of 15
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION ...
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent
use. A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of
breathing zone contaminant and the chemical nature of the contaminant.
Protection Factors (defined as the ratio of contaminant outside and inside the
mask) may also be important.
Breathing Zone Maximum Protection Half-face Full-Face
Level ppm (volume) Factor Respirator Respirator
1000 10 AK-AUS P- -
1000 50 - AK-AUS P-
5000 50 Airline * -
5000 100 - AK-2 P-
10000 100 - AK-3 P-
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand
The local concentration of material, quantity and conditions of use determine
the type of personal protective equipment required. For further information
consult site specific CHEMWATCH data (if available), or your Occupational
Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. If risk of
overexposure exists, wear SAA approved respirator. Correct fit is essential to
obtain adequate protection. Provide adequate ventilation in warehouse or closed
storage areas.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Moderately viscous clear brownish liquid; mixes with water.
PHYSICAL PROPERTIES
Liquid.
Mixes with water.
Molecular Weight: Not Applicable Boiling Range (掳C): Not Available
Melting Range (掳C): Not Available Specific Gravity (water=1): Not Available
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 10 of 15
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES ...
Solubility in water (g/L): Miscible pH (as supplied): 7.5-8.5
pH (1% solution): Not Available Vapour Pressure (kPa): Not Available
Volatile Component (%vol): Not Available Evaporation Rate: Not Available
Relative Vapour Density (air=1): Not Available Flash Point (掳C): Not Applicable
Lower Explosive Limit (%): Not Applicable Upper Explosive Limit (%): Not Applicable
Autoignition Temp (掳C): Not Applicable Decomposition Temp (掳C): Not Available
State: Liquid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
鈥? Presence of incompatible materials.
鈥? Product is considered stable.
鈥? Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The material has NOT been classified by EC Directives or other classification
systems as "harmful by ingestion". This is because of the lack of corroborating
animal or human evidence. The material may still be damaging to the health of
the individual, following ingestion, especially where pre-existing organ (e.g
liver, kidney) damage is evident. Present definitions of harmful or toxic
substances are generally based on doses producing mortality rather than those
producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may
produce nausea and vomiting. In an occupational setting however, ingestion of
insignificant quantities is not thought to be cause for concern.
EYE
Although the liquid is not thought to be an irritant (as classified by EC
Directives), direct contact with the eye may produce transient discomfort
characterised by tearing or conjunctival redness (as with windburn).
SKIN
The material is not thought to produce adverse health effects or skin irritation
following contact (as classified by EC Directives using animal models).
Nevertheless, good hygiene practice requires that exposure be kept to a minimum
and that suitable gloves be used in an occupational setting.
Entry into the blood-stream, through, for example, cuts, abrasions or lesions,
may produce systemic injury with harmful effects. Examine the skin prior to the
use of the material and ensure that any external damage is suitably protected.
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 11 of 15
Section 11 - TOXICOLOGICAL INFORMATION ...
INHALED
Not normally a hazard due to non-volatile nature of product.
The material is not thought to produce adverse health effects or irritation of
the respiratory tract (as classified by EC Directives using animal models).
Nevertheless, good hygiene practice requires that exposure be kept to a minimum
and that suitable control measures be used in an occupational setting.
CHRONIC HEALTH EFFECTS
Substance accumulation, in the human body, may occur and may cause some concern following
repeated or long-term occupational exposure. Limited evidence shows that inhalation of the
material is capable of inducing a sensitisation reaction in a significant number of
individuals at a greater frequency than would be expected from the response of a normal
population. Pulmonary sensitisation, resulting in hyperactive airway dysfunction and
pulmonary allergy may be accompanied by fatigue, malaise and aching. Significant symptoms
of exposure may persist for extended periods, even after exposure ceases. Symptoms can be
activated by a variety of nonspecific environmental stimuli such as automobile exhaust,
perfumes and passive smoking. . There exists limited evidence that shows that skin contact
with the material is capable either of inducing a sensitisation reaction in a significant
number of individuals, and/or of producing positive response in experimental animals.
Absorbed sulfonates are quickly distributed through living systems and are readily
excreted. Toxic effects may result from the effects of binding to proteins and the ability
of sulfonates to translocate potassium and nitrate (NO3-) ions from cellular to
interstitial fluids. Airborne sulfonates may be responsible for respiratory allergies and,
in some instances, minor dermal allergies. Prolonged or chronic exposure to alkanolamines
may result in liver, kidney or nervous system injury. Repeated inhalation may aggravate
asthma and inflammatory or fibrotic pulmonary disease. Results of repeated exposure tests
with diethanolamine (DEA) in laboratory animals include anaemia (rats) and effects on the
kidneys (rats and mice) and liver (mice). DEA produces nervous system injury in dogs and
rats. Heart and salivary gland lesions have also been seen in mice treated cutaneously
with DEA and in mice receiving DEA in drinking water. Rats given high doses of DEA
developed anaemia and testicular lesions. Exaggerated doses of DEA produced heart and
nervous system effects in other animals. Changes in other organs were judged to be
secondary due to the poor health of animals subjected to extremely high doses of DEA.
Rats, rabbits and guinea pigs exposed to high vapour concentrations of volatile
monoethanolamine (MEA) (up to 1250 ppm) for periods of up to 5 weeks developed pulmonary,
hepatic and renal lesions. Dogs, rats and guinea pigs exposed to 100 ppm MEA for 30 days,
became apathetic and developed poor appetites. Animal tests also indicate that inhalation
exposure to MEA may result in nervous system injury. All species exposed to airborne MEA
experienced dermal effects, varying from ulceration to hair loss probably resulting from
contact with the cage. An increased incidence of skeletal variations, suggestive of a
slight developmental delay was seen in the foetuses of rats given 1500 mg/kg/day DEA
cutaneously; this also produced significant maternal toxicity. No foetal malformations,
however, were seen in rats nor in rabbits receiving identical treatment. The foetus of
rats given high doses of MEA by gavage, showed an increased rate of embryofoetal death,
growth retardation, and some malformations including hydronephrosis and hydroureter. The
high doses required to produce these effects bring into question the relevance of this
finding to humans. There is some evidence that embryofoetotoxicity and teratogenicity does
not occur in rats when MEA is administered by dermal application to the mother. The
National Toxicology Program (NTP) concluded that there is clear evidence of liver tumours
and some evidence of kidney tumours in mice exposed dermally to DEA over their lifetime.
Chronic skin painting studies in mice of both sexes produced liver tumours and an
increased incidence of kidney tumours in male mice. The significance of these findings to
humans is unclear as DEA is neither genotoxic, mutagenic nor clastogenic, and did not
induce tumours in rats or transgenic mice similarly treated. Alkanolamines (especially
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 12 of 15
Section 11 - TOXICOLOGICAL INFORMATION ...
those containing a secondary amine moiety) may react with nitrites or other nitrosating
agents to form carcinogenic N-nitrosamines. Alkanolamines are metabolised by biosynthetic
routes to ethanolamine and choline and incorporated into phospholipids. They are excreted
predominantly unchanged with a half-life of approximately one week. In the absence of
sodium nitrite, no conversion to carcinogenic N-nitrosamines was observed. Diethanolamine
competitively inhibits the cellular uptake of choline, in vitro, and hepatic changes in
choline homeostasis, consistent with choline deficiency, are observed in vivo. Many amines
are potent skin and respiratory sensitisers and certain individuals especially those
described as "atopic" (i.e. those predisposed to asthma and other allergic responses) may
show allergic reactions when chronically exposed to alkanolamines. In a study with coconut
diethanolamide, the National Toxicology Program (Technical Report Series 479), showed
clear evidence of carcinogenic activity in male B6C3F1 mice based on increased incidences
of hepatic and renal tubule neoplasms and in female B6C3F1 mice based on increased
incidences of hepatic neoplasms. There was equivocal evidence of carcinogenic activity in
female F344/N rats based on a marginal increase in the incidence of renal tube neoplasms.
These increases were associated with the concentration of free diethanolamine present as a
contaminant in the diethanolamine condensate. Exposure to rats to coconut oil
diethanolamine condensate by dermal application in ethanol for 2 years resulted in
epidermal hyperplasia, sebaceous gland hyperplasia, hyperkeratosis and parakeratosis in
males and females and ulcer in females at the site of application. There were increases in
the incidences of chronic inflammation, epithelial hyperplasia, and epithelial ulcer in
the forestomach of female rats. The severity of nephropathy in dosed female rats were
increased. Exposure of mice to coconut oil diethanolamine condensate by dermal application
for 2 years resulted in increased incidences of eosinophilic foci of the liver in males.
Increased incidences of epidermal hyperplasia, sebaceous gland hyperplasia, and
hyperkeratosis in males and females, ulcer in males, and parakeratosis and inflammation in
females at the site of application and of follicular cell hyperplasia in the thyroid gland
of males and females, were chemical related. Acyl sarcosines and acyl sarcosinates are
reportedly cytotoxic to Chinese hamster cells in culture but are not mutagenic to these
cells, nor to bacterial cells in culture. They are generally of low oral rat toxicity and
nonirritating and nonsensitising to animal and human skin. Several are reportedly
photosensitisers. This family of materials is often used in formulations requiring anionic
surfactants; they may enhance the penetration of other ingredients through the skin and
caution should be exhibited when formulating cosmetic products containing substances which
are systemic toxins but which do not normally penetrate the skin. Because sarcosine can be
nitrosated to form N-nitrososarcosine, a known animal carcinogen, sarcosines
(N-methylglycine derivatives) and their salts (sarcosinates) are not generally compounded
with agents which might promote such reaction.
Kitten Glo-Wash
Not available. Refer to individual constituents.
unless otherwise specified data extracted from RTECS - Register of Toxic Effects
of Chemical Substances
(C10-16)ALKYLBENZENESULFONIC ACID, SODIUM SALT:
TOXICITY IRRITATION
Data for sodium dodecylbenzenesulfonate
Oral (rat) LD50: 438 mg/kg Skin (rabbit): 20 mg/24 hr-SEVERE
Eye (rabbit): 0.25 mg/24hr-SEVERE
Eye (rabbit): 1% - SEVERE
DIETHANOLAMINE COCOATE:
No significant acute toxicological data identified in literature search.
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 13 of 15
Section 11 - TOXICOLOGICAL INFORMATION ...
SODIUM SULFATE:
TOXICITY IRRITATION
Oral (mouse) LD50: 5989 mg/kg Nil reported
Equivocal Tumorigen by RTECS criteria.
Reproductive effector in mice.
DIETHANOLAMINE:
TOXICITY IRRITATION
Oral (rat) LD50: 710 mg/kg Skin (rabbit): 50 mg (open)-mild
Dermal (rabbit) LD50: 12200 mg/kg Skin (rabbit): 500 mg/24 hr-mild
Eye (rabbit): 5500 mg - SEVERE
Eye (rabbit):0.75 mg/24 hr SEVERE
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
LAUROYLSARCOSINE, SODIUM SALT:
TOXICITY IRRITATION
Oral (rat) LD50: 5000 mg/kg * Nil reported
* Dow Chemical
GLYCEROL:
TOXICITY IRRITATION
Oral (human) TDLo : 1428 mg/kg Skin (rabbit): 500 mg/24h mild
Oral (rat) LD50 : 12600 mg/kg Eye (rabbit): 126 mg mild
Eye (rabbit): 500 mg/24h mild
EDTA TETRASODIUM SALT:
TOXICITY IRRITATION
Oral (rat) LD50: 2000-3200 mg/kg* Skin (rabbit):500 mg/24h-moderate
Eyes (rabbit): 1.9 mg
Eyes (rabbit):100 mg/24h-moderate
*[BASF]
1,2-BENZISOTHIAZOLIN-3-ONE, SODIUM SALT:
TOXICITY IRRITATION
as CAS RN 2634-33-5 1,2-benzisothiazol-3(2H)-one
Oral (rat) LD50: 1020 mg/kg Nil reported
WATER:
No significant acute toxicological data identified in literature search.
Section 12 - ECOLOGICAL INFORMATION
Octanol/water partition coefficients cannot easily be determined for surfactants
because one part of the molecule is hydrophilic and the other part is
hydrophobic. Consequently they tend to accumulate at the interface and are not
extracted into one or other of the liquid phases. As a result surfactants are
expected to transfer slowly, for example, from water into the flesh of fish.
During this process, readily biodegradable surfactants are expected to be
metabolised rapidly during the process of bioaccumulation. This was emphasised
by the OECD Expert Group stating that chemicals are not to be considered to show
bioaccumulation potential if they are readily biodegradable.
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 14 of 15
Section 12 - ECOLOGICAL INFORMATION ...
Several anionic and nonionic surfactants have been investigated to evaluate
their potential to bioconcentrate in fish. BCF values (BCF - bioconcentration
factor) ranging from 1 to 350 were found. These are absolute maximum values,
resulting from the radiolabelling technique used. In all these studies,
substantial oxidative metabolism was found resulting in the highest
radioactivity in the gall bladder. This indicates liver transformation of the
parent compound and biliary excretion of the metabolised compounds, so that
"real" bioconcentration is overstated. After correction it can be expected that
"real" parent BCF values are one order of magnitude less than those indicated
above, i.e. "real" BCF is <100. Therefore the usual data used for classification
by EU directives to determine whether a substance is "Dangerous to the
"Environment" has little bearing on whether the use of the surfactant is
environmentally acceptable.
DO NOT discharge into sewer or waterways.
Section 13 - DISPOSAL CONSIDERATIONS
鈥? Recycle wherever possible.
鈥? Consult manufacturer for recycling options or consult local or regional waste
management authority for disposal if no suitable treatment or disposal facility
can be identified.
鈥? Dispose of by: Burial in a licenced land-fill or Incineration in a licenced
apparatus (after admixture with suitable combustible material)
鈥? Decontaminate empty containers. Observe all label safeguards until containers
are cleaned and destroyed.
Puncture containers to prevent re-use and bury at an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
Shipping Name:
None
Dangerous Goods Class: None
UN/NA Number: None
ADR Number:
Packing Group: None
Labels Required:
Additional Shipping Information:
International Transport Regulations:
IMO: None
HAZCHEM
None
Section 15 - REGULATORY INFORMATION
continued...
KITTEN GLO-WASH
ChemWatch Material Safety Data Sheet CHEMWATCH 53006
Issue Date: Mon 16-Aug-2004 CD 2004/3 Page 15 of 15
Section 15 - REGULATORY INFORMATION ...
POISONS SCHEDULE
None
REGULATIONS
No data available for (C10-16)alkylbenzenesulfonic acid, sodium salt
as (CAS: 68081-81-2). (CAS: 8051-30-7). (CAS: 7757-82-6). (CAS:
111-42-2). (CAS: 137-16-6). (CAS: 56-81-5). (CAS: 64-02-8). (CAS:
10378-23-1). (CAS: 13235-36-4). (CAS: 58249-25-5). (CAS: 7732-18-5).
Section 16 - OTHER INFORMATION
This document is copyright. Apart from any fair dealing for the purposes of
private study, research, review or criticism, as permitted under the Copyright
Act, no part may be reproduced by any process without written permission from
CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: Mon 16-Aug-2004
Print Date: Tue 31-Aug-2004
|