SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 24/MAY/2005
Date Updated: 12/MAR/2004
Version 1.4
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 1,1,2,2-TETRACHLOROETHANE, REAGENT
GRADE, 98%
Product Number 185434
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
1,1,2,2-TETRACHLOROETHANE 79-34-5 201-197-8 602-015-00-3
Formula C2H2Cl4
Molecular Weight 167.85 AMU
Synonyms Acetylene tetrachloride * Bonoform * Cellon *
1,1,2,2-Czterochloroetan (Polish) *
1,1-Dichloro-2,2-dichloroethane * NCI-C03554 *
RCRA waste number U209 * TCE *
1,1,2,2-Tetrachloorethaan (Dutch) *
1,1,2,2-Tetrachloraethan (German) *
Tetrachlorethane * 1,1,2,2-Tetrachloroethane *
1,1,2,2-Tetrachlorethane (French) *
Tetrachloroethane * s-Tetrachloroethane *
sym-Tetrachloroethane *
1,1,2,2-Tetrachloroethane (ACGIH:OSHA) *
1,1,2,2-Tetracloroetano (Italian) *
Tetrachlorure d'acetylene (French) * Westron
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Very toxic by inhalation and in contact with skin Toxic to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
prolonged or repeated exposure. Do not get in eyes, on skin, on
clothing.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS
Country Source Type Value
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Poland NDS 5 MG/M3
Poland NDSCh 35 MG/M3
Poland NDSP -
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 7 mg/m3
1 ppm
Remarks: H
EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 7 mg/m3
1 ppm
Remarks: H
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 7 mg/m3
1 ppm
Remarks: H
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 7 mg/m3
1 ppm
Remarks: H
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: Colorless
Form: Clear liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 144 - 146 掳C
MP/MP Range -43 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 8 mmHg 20 掳C
SG/Density 1.597 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density 5.8 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
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Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Sodium, Strong bases,
Potassium Reacts violently with nitrates and 2,4-dinitrophenyl
disulfide.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: KI8575000
ACUTE TOXICITY
LD50
Oral
Rat
200 mg/kg
LC50
Inhalation
Mouse
4,500 mg/m3
2H
LD50
Intraperitoneal
Mouse
821 MG/KG
LD50
Subcutaneous
Mouse
1108 MG/KG
Remarks: Behavioral:Sleep. Behavioral:Ataxia.
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Headache. Nausea. Vomiting. Tremors.
Incoordination. Fatigue. Dizziness. Anorexia.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be fatal if absorbed through skin. Readily
absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: May be fatal if inhaled. Material may be irritating
to mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Nerves. Liver. Blood.
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CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that has been
reported to be possibly carcinogenic based on its IARC, ACGIH,
NTP, or EPA classification.
Rat
Route of Application: Oral
Exposure Time: 78W
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Liver:Tumors.
Mouse
Route of Application: Oral
Exposure Time: 78W
Result: Tumorigenic:Carcinogenic by RTECS criteria. Liver:Tumors.
Mouse
Route of Application: Oral
Exposure Time: 78W
Result: Tumorigenic:Carcinogenic by RTECS criteria. Liver:Tumors.
IARC CARCINOGEN LIST
Rating: Group 3
CHRONIC EXPOSURE - MUTAGEN
Human
6 MMOL/L
Cell Type: HeLa cell
DNA inhibition
Mouse
200 MG/KG
Oral
Other mutation test systems
Hamster
56 MG/L
Cell Type: ovary
Sister chromatid exchange
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
Test Type: LC50 Fish
Species: Pimephales promelas (Fathead minnow)
Time: 96 h
Value: 20 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
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RID/ADR
UN#: 1702
Class: 6.1
PG: II
Proper Shipping Name: 1,1,2,2-Tetrachloroethane
IMDG
UN#: 1702
Class: 6.1
PG: II
Proper Shipping Name: 1,1,2,2-Tetrachloroethane
Marine Pollutant: Yes
Severe Marine Pollutant: No
IATA
UN#: 1702
Class: 6.1
PG: II
Proper Shipping Name: 1,1,2,2-Tetrachloroethane
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 602-015-00-3
INDICATION OF DANGER: T+ N
Very toxic. Dangerous for the environment.
R-PHRASES: 26/27 51/53
Very toxic by inhalation and in contact with skin Toxic to
aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
S-PHRASES: 38 45 61
In case of insufficient ventilation, wear suitable respiratory
equipment. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
Avoid release to the environment. Refer to special
instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 1*
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
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For R&D use only. Not for drug, household or other uses.
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