SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 27/MAY/2005
Date Updated: 13/MAR/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 2-METHYL-2-BUTANOL, REAGENTPLUSTM, >=99%
Product Number 240486
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
2-METHYL-2-BUTANOL 75-85-4 200-908-9 603-007-00-2
Formula C5H12O
Molecular Weight 88.15 AMU
Synonyms tert-Amyl alcohol * Amylene hydrate * 2-Butanol,
2-methyl- * Dimethylethylcarbinol * Ethyl
dimethyl carbinol * 2-Methyl butanol-2 *
2-Methyl-2-butanol * 3-Methyl-butanol-(3)
(German) * 3-Methylbutan-3-ol * tert-Pentanol
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Harmful by inhalation.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
Unsuitable: Water may be effective for cooling, but may not
effect extinguishment.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition. Use nonsparking
tools.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Mechanical
exhaust required.
GENERAL HYGIENE MEASURES
Remove and wash contaminated clothing promptly. Wash thoroughly
after handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 360 mg/m3
100 ppm
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EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 360 mg/m3
Remarks: DK
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 180 mg/m3
50 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Color: Colorless
Form: Clear liquid
Property Value At Temperature or Pressure
pH 6 20 掳C Concentration: 118
g/l
BP/BP Range 100 - 103 掳C
MP/MP Range -12 掳C
Flash Point 20 掳C Method: closed cup
Flammability N/A
Autoignition Temp 437 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 1.2 %
Upper: 9 %
Vapor Pressure 12 mmHg 20 掳C
SG/Density 0.808 g/cm3
Partition Coefficient Log Kow: 0.77
Viscosity N/A
Vapor Density 3 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
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RTECS NUMBER: SC0175000
ACUTE TOXICITY
LD50
Oral
Rat
1000 mg/kg
Remarks: Behavioral:Ataxia.
LD50
Subcutaneous
Mouse
2100 MG/KG
LD50
Intravenous
Mouse
610 MG/KG
LD50
Oral
Rabbit
2028 mg/kg
Remarks: Sense Organs and Special Senses (Nose, Eye, Ear, and
Taste):Eye:Corneal damage. Cardiac:Pulse rate. Lungs, Thorax, or
Respiration:Dyspnea.
IRRITATION DATA
Skin
Rabbit
Remarks: No irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Prolonged exposure can cause: Nausea, dizziness, and headache.
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation. Lachrymator.
Inhalation: Harmful if inhaled. Material is irritating to mucous
membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Central nervous system.
12 - Ecological Information
ELIMINATION
Elimination: 40 - 50 %
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Algae
Species: Scenedesmus subspicatus
Time: 72 h
Value: > 500 mg/l
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Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 540 mg/l
Test Type: LC50 Fish
Species: Leuciscus idus
Time: 48 h
Value: 2,430 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1105
Class: 3
PG: II
Proper Shipping Name: PENTANOLS
IMDG
UN#: 1105
Class: 3
PG: II
Proper Shipping Name: PENTANOLS
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1105
Class: 3
PG: II
Proper Shipping Name: PENTANOLS
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 603-007-00-2
INDICATION OF DANGER: F Xn
Highly Flammable. Harmful.
R-PHRASES: 11 20
Highly flammable. Harmful by inhalation.
S-PHRASES: 9 16 24/25
Keep container in a well-ventilated place. Keep away from
sources of ignition - no smoking. Avoid contact with skin and
eyes.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1
SWITZERLAND
SWISS POISON CLASS: 4
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NORWAY
Labelling for organic solvents where the package is 1liter or
more.
YL-tall m3/l: 4500
YL-group: 5
Safety phrases: 38 42 210
In case of insufficient ventilation, wear suitable respiratory
equipment. During fumigation/spraying wear suitable respiratory
equipment. Use compressed air- or fresh air line breathing
apparatus in confined spaces.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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