SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 26/MAY/2005
Date Updated: 13/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name TARTRAZINE, FOR MICROSCOPY
Product Number 86310
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
TARTRAZINE 1934-21-0 217-699-5 None
Formula C16H9N4Na3O9S2
Molecular Weight 534.37 AMU
Synonyms Acid Leather Yellow T * Acid Yellow 23 * Acid
Yellow T * Acilan Yellow GG * A.F. Yellow No. 4
* Airedale Yellow T * Aizen tartrazine * Amacid
Yellow T * Atul Tartrazine * Bucacid tartrazine
* Calcocid Yellow MCG * Calcocid Yellow XX *
Canacert tartrazine *
3-Carboxy-5-hydroxy-1-p-sulfophenyl-4-p-sulfophen
ylazopyrazole trisodium salt * Certicol
Tartrazol Yellow S * Cilefa Yellow T * C.I. 640
* C.I. 19140 * C.I. Acid Yellow 23 * C.I. Acid
Yellow 23, trisodium salt * C.I. Food Yellow 4 *
Curon Fast Yellow 5G * D and C Yellow No. 5 *
Dolkwal tartrazine * Dye FD and C Yellow No. 5 *
E 102 * Edicol Supra Tartrazine N * Egg Yellow A
* Erio Tartrazine * Eurocert tartrazine * FD and
C Yellow 5 * FD & C Yellow No. 5 tartrazine *
Fenazo Yellow T * Food Yellow 4 * Food Yellow 5
* HD tartrazine * HD Tartrazine Supra * Hexacert
Yellow No. 5 * Hexacol tartrazine * Hidazid
tartrazine * Hispacid Fast Yellow T * Hydrazine
Yellow * Hydroxine Yellow L * Kako tartrazine *
Kayaku Food Colour Yellow No. 4 * Kayaku
tartrazine * Kca Foodcol Tartrazine PF * Kca
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause sensitization by inhalation and skin contact.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Avoid breathing dust. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS: Hygroscopic.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Mechanical exhaust required.
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GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Form: Powder
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions to Avoid: Moisture.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides, Sodium oxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: UQ6400000
ACUTE TOXICITY
LD50
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Intraperitoneal
Rat
>2 GM/KG
LD50
Intravenous
Rat
>2 GM/KG
LD50
Oral
Mouse
12750 mg/kg
SENSITIZATION
Respiratory: May cause allergic respiratory reaction.
Skin: May cause allergic skin reaction.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled. Material may be
irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
CHRONIC EXPOSURE - MUTAGEN
Human
100 MG/L
Cell Type: lymphocyte
Cytogenetic analysis
Rat
1500 MG/KG
Cell Type: S. typhimurium
Body fluid assay
Hamster
2500 MG/L
Cell Type: fibroblast
Cytogenetic analysis
Hamster
2100 MG/L
Cell Type: lung
Cytogenetic analysis
Mammal
5 MG/L
Cell Type: fibroblast
Cytogenetic analysis
ZNEG
Histidine reversion (Ames)
CHRONIC EXPOSURE - TERATOGEN
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Species: Rat
Dose: 18500 MG/KG
Route of Application: Oral
Exposure Time: (7-22D PREG/21D POST)
Result: Specific Developmental Abnormalities: Blood and
lymphatic system (including spleen and marrow). Effects on
Newborn: Growth statistics (e.g., reduced weight gain). Effects
on Newborn: Behavioral.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 1280 MG/KG
Route of Application: Oral
Exposure Time: (7-14D PREG)
Result: Effects on Newborn: Weaning or lactation index (e.g., #
alive at weaning per # alive at day 4).
Species: Rat
Dose: 20 GM/KG
Route of Application: Oral
Exposure Time: (7-14D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 42/43
May cause sensitization by inhalation and skin contact.
S-PHRASES: 22 36/37 45
Do not breathe dust. Wear suitable protective clothing and
gloves. In case of accident or if you feel unwell, seek medical
advice immediately (show the label where possible).
COUNTRY SPECIFIC INFORMATION
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Germany
WGK: 1
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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