SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 26/MAY/2005
Date Updated: 16/SEP/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name 1,1,2,2-TETRABROMOETHANE, 98%
Product Number 185574
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
1,1,2,2-TETRABROMOETHANE 79-27-6 201-191-5 602-016-00-9
Formula C2H2Br4
Molecular Weight 345.67 AMU
Synonyms Acetylene tetrabromide (ACGIH:OSHA) * Muthmann's
liquid * TBE * 1,1,2,2-Tetrabromaethan (German)
* Tetrabromoacetylene * 1,1,2,2-Tetrabromoetano
(Italian) * s-Tetrabromoethane *
1,1,2,2-Tetrabromoethane *
1,1,2,2-Tetrabroomethaan (Dutch)
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Very toxic by inhalation. Irritating to eyes. Harmful to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS
Country Source Type Value
Poland NDS 4 mg/m3
Poland NDSCh -
Poland NDSP
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 14 mg/m3
1 ppm
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EXPOSURE LIMITS - GERMANY
Source Type Value
TRGS 900 OEL 14 mg/m3
1 ppm
Remarks: 4
EXPOSURE LIMITS - NORWAY
Source Type Value
OEL 14 mg/m3
1 ppm
EXPOSURE LIMITS - SWEDEN
Source Type Value
LLV (Level14 mg/m3
1 ppm
EXPOSURE LIMITS - SWITZERLAND
Source Type Value
OEL OEL 14 mg/m3
1 ppm
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL OEL 7.2 mg/m3
0.5 ppm
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Color: Almost colorless
Form: Clear liquid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 223 - 229 掳C
MP/MP Range -1 - 1 掳C
Flash Point N/A
Flammability N/A
Autoignition Temp 335 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure 0.1 mmHg 20 掳C
SG/Density 2.963 g/cm3
Partition Coefficient Log Kow: 1.98
Viscosity N/A
Vapor Density 11.9 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
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Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: Heat sensitive.
Materials to Avoid: Strong bases, Strong oxidizing agents,
Chemically active metals, Aluminum, Magnesium, Zinc.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Hydrogen bromide gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: KI8225000
ACUTE TOXICITY
LD50
Oral
Rat
1200 mg/kg
LC50
Inhalation
Rat
549 mg/m3
4H
LD50
Skin
Rat
5250 mg/kg
LD50
Oral
Mouse
269 mg/kg
LD50
Intraperitoneal
Mouse
443 MG/KG
LD50
Oral
Rabbit
400 mg/kg
Remarks: Behavioral:General anesthetic. Liver:Fatty liver
degeneration. Blood: Hemorrhage.
LD50
Oral
Guinea pig
400 mg/kg
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IRRITATION DATA
Skin
Rabbit
500 mg
24H
Remarks: Moderate irritation effect
Eyes
Rabbit
100 mg
Remarks: Mild irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Nausea, dizziness, and headache. Anorexia.
Cholestatic jaundice. To the best of our knowledge, the
chemical, physical, and toxicological properties have not been
thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Toxic if inhaled. Material is irritating to mucous
membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
TARGET ORGAN INFORMATION
Nerves. Liver. Kidneys.
CHRONIC EXPOSURE - CARCINOGEN
Mouse
Route of Application: Skin
Exposure Time: 74W
Result: Tumorigenic:Neoplastic by RTECS criteria. Lungs, Thorax,
or Respiration:Tumors. Skin and Appendages: Other: Tumors.
CHRONIC EXPOSURE - MUTAGEN
Hamster
158 MG/L
Cell Type: ovary
Sister chromatid exchange
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2504
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Class: 6.1
PG: III
Proper Shipping Name: Tetrabromoethane
IMDG
UN#: 2504
Class: 6.1
PG: III
Proper Shipping Name: Tetrabromoethane
Marine Pollutant: Yes
Severe Marine Pollutant: No
IATA
UN#: 2504
Class: 6.1
PG: III
Proper Shipping Name: Tetrabromoethane
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 602-016-00-9
INDICATION OF DANGER: T+
Very toxic.
R-PHRASES: 26 36 52/53
Very toxic by inhalation. Irritating to eyes. Harmful to
aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
S-PHRASES: 24 27 45 61
Avoid contact with skin. Take off immediately all contaminated
clothing. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
Avoid release to the environment. Refer to special
instructions/safety data sheets.
SWITZERLAND
SWISS POISON CLASS: 2
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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