SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 28/JUN/2005
Date Updated: 13/MAR/2004
Version 1.2
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name DIBUTYLTIN DICHLORIDE, 96%
Product Number 205494
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
DIBUTYLTIN DICHLORIDE 683-18-1 211-670-0 None
Formula C8H18Cl2Sn
Molecular Weight 303.83 AMU
Synonyms Chlorid di-n-butylcinicity (Czech) * D.B.T.C. *
Dibutyldichlorostannane * Dibutyldichlorotin *
Dibutylstannium dichloride * Dibutyltin chloride
* Dibutyltin dichloride * Di-n-butyltin
dichloride * Di-n-butyl-zinn-dichlorid (German)
* Dichlorodibutylstannane * Dichlorodibutyltin *
Tin, dibutyl-, dichloride
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Causes burns. Toxic if swallowed. Toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Water hydrolyzes material liberating acidic gas which in contact
with metal surfaces can generate flammable and/or explosive
hydrogen gas.
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS: Moisture sensitive.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Use only in a chemical fume hood. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Discard contaminated
shoes. Wash thoroughly after handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.1 mg/m3
Remarks: SKIN
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EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.1MG(SN)/M3
OEL STEL 0.2 mg(Sn)/m3
Remarks: Skin
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: Colorless
Form: Solidified mass or fragments
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 135 掳C 10 mmHg
MP/MP Range 37 掳C
Flash Point 113 掳C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1.37 - 1.4 g/cm3 20 掳C
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: May decompose on exposure to moist air
or water.
Conditions to Avoid: Heat.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Tin/tin oxides, Hydrogen chloride gas.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
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RTECS NUMBER: WH7100000
ACUTE TOXICITY
LD50
Oral
Rat
50 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Gastrointestinal:Hypermotility, diarrhea. Blood: Hemorrhage.
LC50
Inhalation
Rat
> 364 mg/m3
4H
Remarks: Behavioral:Tremor.
LD50
Oral
Mouse
70 mg/kg
LD50
Intravenous
Mouse
180 MG/KG
LD50
Oral
Rabbit
0.05 mg/kg
IRRITATION DATA
Skin
Rabbit
2 mg
24H
Remarks: Severe irritation effect
Eyes
Rabbit
0.05 mg
24H
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes burns.
Skin Absorption: May be harmful if absorbed through the skin.
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Eye Contact: Causes burns.
Inhalation: Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract. May be harmful
if inhaled.
Ingestion: Toxic if swallowed.
CHRONIC EXPOSURE - MUTAGEN
Hamster
100 UG/L
Cell Type: ovary
Mutation in mammalian somatic cells.
Rabbit
10 UG/L
Cell Type: Other cell types
Unscheduled DNA synthesis
Rabbit
100 UG/L
Cell Type: Other cell types
DNA inhibition
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 45 MG/KG
Route of Application: Oral
Exposure Time: (7-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus). Specific Developmental Abnormalities:
Craniofacial (including nose and tongue). Specific Developmental
Abnormalities: Musculoskeletal system.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 20 MG/KG
Route of Application: Oral
Exposure Time: (8D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Embryo or Fetus: Fetotoxicity (except death, e.g.,
stunted fetus). Specific Developmental Abnormalities:
Musculoskeletal system.
Species: Rat
Dose: 150 MG/KG
Route of Application: Oral
Exposure Time: (13-15D PREG)
Result: Maternal Effects: Other effects. Effects on Embryo or
Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Species: Rat
Dose: 20 MG/KG
Route of Application: Oral
Exposure Time: (7-8D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
Effects on Fertility: Litter size (e.g.; # fetuses per litter;
measured before birth). Effects on Embryo or Fetus: Fetotoxicity
(except death, e.g., stunted fetus).
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Species: Rat
Dose: 15200 UG/KG
Route of Application: Oral
Exposure Time: (4-7D PREG)
Result: Effects on Fertility: Post-implantation mortality (e.g.,
dead and/or resorbed implants per total number of implants).
12 - Ecological Information
ELIMINATION
Elimination: 6 %
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Daphnia
Species: Daphnia magna
Value: 1.4 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 24 h
Value: 0.9 mg/l
Test Type: LC50 Fish
Time: 96 h
Value: > 4.8 mg/l
Test Type: EC50 Algae
Species: Scenedesmus subspicatus
Time: 96 h
Value: 0.02 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2928
Class: 6.1
PG: II
Proper Shipping Name: Toxic solid, corrosive, organic,
n.o.s.
IMDG
UN#: 2928
Class: 6.1
PG: II
Subrisk: 8
Proper Shipping Name: TOXIC SOLID, CORROSIVE, ORGANIC,
N.O.S.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
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IATA
UN#: 2928
Class: 6.1
PG: II
Subrisk: 8
Proper Shipping Name: Toxic solid, corrosive, organic,
n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: T N
Toxic. Dangerous for the environment.
R-PHRASES: 34 25 51/53
Causes burns. Toxic if swallowed. Toxic to aquatic organisms,
may cause long-term adverse effects in the aquatic environment.
S-PHRASES: 26 36/37/39 45 61
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. Wear suitable protective
clothing, gloves, and eye/face protection. In case of accident
or if you feel unwell, seek medical advice immediately (show
the label where possible). Avoid release to the environment.
Refer to special instructions/safety data sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
SWITZERLAND
SWISS POISON CLASS: 2
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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